Trials and Studies - Canadian Critical Care Trials Group

Steroid Use in Pediatric Fluid and Vasoactive Infusion Dependent Shock (STRIPES)

STRIPES

Principal Investigator(s):

Kusum Menon

STRIPES

Stress Hydrocortisone in Pediatric Septic Shock (SHIPSS)

SHIPSS

Principal Investigator(s):

Kusum Menon, Michael Agus, Jerry Zimmerman, David Wypij

Enrolling

SHIPSS

TAME

Principal Investigator(s):

Jim Kutsogiannis, Sean Bagshaw

TBI international platform trial (BRAINapt)

BRAINapt

Principal Investigator(s):

Alexis Turgeon

BRAINapt

TBI-Prognosis

Principal Investigator(s):

Alexis Turgeon

TBI-QualE

Principal Investigator(s):

Alexis Turgeon

Temperature, Heart and Respiratory Rate Investigation along with Variability Evaluation and Serum Biomarkers Study (THRRIVES)

THRRIVES

Principal Investigator(s):

Andrew Seely, Christopher Bredeson

Enrolment Complete

THRRIVES

Temporal Changes in Thrombin Generation, Protein C Levels and Activated Protein C Generation in Early Septic Shock (PRECISE)

PRECISE

Principal Investigator(s):

Lauralyn McIntyre

PRECISE

The Corticosteroids Early and Extended Domains of the PRACTICAL platform RCT (CORT-E2)

CORT-E2

Principal Investigator(s):

Bram Rochwerg, Lorenzo del Sorbo

In Development

CORT-E2

The dying process in children after withdrawal of life sustaining therapies and organ donation after circulatory death – exploring time to death, auto-resuscitation and impact on families

Principal Investigator(s):

Conall Francoeur

The EXercise and Early Rehabilitation in Critically Ill Children: a Systematic Evaluation (EXERCISE)

EXERCISE

Principal Investigator(s):

Karen Choong

EXERCISE

The frailty, outcomes, recovery and care steps of critically ill patients study (FORECAST)

FORECAST

Principal Investigator(s):

John Muscedere, Sean Bagshaw

Enrolment Complete

FORECAST

The impact of the COVID-19 pandemic on intensive care unit workers: a nationwide survey

Principal Investigator(s):

Sangeeta Mehta

Enrolment Complete

The Larynx, Trachea and Swallowing after prolonged intubation or tracheostomy Study

Principal Investigator(s):

Sangeeta Mehta

The Role of Active Deresuscitation after Resuscitation program (RADAR)

RADAR

Principal Investigator(s):

John Marshall

In Development

RADAR

The safety of discharging children directly home from the pediatric intensive care unit: A Canadian population cohort

Principal Investigator(s):

Nadia Roumeliotis

Therapeutic Plasma Exchange in Septic Shock (Plexsis): A Pilot Study

PLEXSIS

Principal Investigator(s):

Ryan Zarychanski, Emily Rimmer

Enrolling

PLEXSIS

THIRST: Transforming Health Information and Research Synthesis through Technology and Teamwork research program (insightScope)

THIRST

Principal Investigator(s):

Dayre McNally

THIRST

Thresholds for invasive ventilation in hypoxemic respiratory failure

Principal Investigator(s):

Christopher Yarnell

In Development

Timing of Initiation of Renal-Replacement Therapy of Acute Kidney Injury (STARRT-AKI)

STARRT-AKI

Principal Investigator(s):

Sean Bagshaw, Ron Wald

Enrolment Complete

STARRT-AKI

Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shock: A Phase II RCT

Principal Investigator(s):

Lauralyn McIntyre

Understanding and managing the effects of COVID-19 restricted visitation policies on the families and healthcare providers of critically ill patients

Principal Investigator(s):

Kirsten Fiest

Enrolment Complete

Understanding Decision Making in Organ Donation: A National Study

Principal Investigator(s):

Michaël Chassé, Justin Presseau, Kimberly Jordison

Enrolling

Understanding nutrition rehabilitation in survivors of critical illness following hospital discharge

Principal Investigator(s):

Lesley Moisey

Find a Trial or Study

Steroid Use in Pediatric Fluid and Vasoactive Infusion Dependent Shock (STRIPES)

Stress Hydrocortisone in Pediatric Septic Shock (SHIPSS)

TAME

TBI international platform trial (BRAINapt)

TBI-Prognosis

TBI-QualE

Temperature, Heart and Respiratory Rate Investigation along with Variability Evaluation and Serum Biomarkers Study (THRRIVES)

Temporal Changes in Thrombin Generation, Protein C Levels and Activated Protein C Generation in Early Septic Shock (PRECISE)

The Corticosteroids Early and Extended Domains of the PRACTICAL platform RCT (CORT-E2)

The dying process in children after withdrawal of life sustaining therapies and organ donation after circulatory death – exploring time to death, auto-resuscitation and impact on families

The EXercise and Early Rehabilitation in Critically Ill Children: a Systematic Evaluation (EXERCISE)

The frailty, outcomes, recovery and care steps of critically ill patients study (FORECAST)

The impact of the COVID-19 pandemic on intensive care unit workers: a nationwide survey

The Larynx, Trachea and Swallowing after prolonged intubation or tracheostomy Study

The Role of Active Deresuscitation after Resuscitation program (RADAR)

The safety of discharging children directly home from the pediatric intensive care unit: A Canadian population cohort

Therapeutic Plasma Exchange in Septic Shock (Plexsis): A Pilot Study

THIRST: Transforming Health Information and Research Synthesis through Technology and Teamwork research program (insightScope)

Thresholds for invasive ventilation in hypoxemic respiratory failure

Timing of Initiation of Renal-Replacement Therapy of Acute Kidney Injury (STARRT-AKI)

Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shock: A Phase II RCT

Understanding and managing the effects of COVID-19 restricted visitation policies on the families and healthcare providers of critically ill patients

Understanding Decision Making in Organ Donation: A National Study

Understanding nutrition rehabilitation in survivors of critical illness following hospital discharge