Trials and Studies - Canadian Critical Care Trials Group

A Canadian Critical Care Knowledge Translation Network (aC3KTion Net)

aC3KTion Net

Principal Investigator(s):

John Muscedere

Enrolment Complete

aC3KTion Net

PREcision meDIcine for CriTical care (PREDICT)-Power Blade: Early Sepsis Severity RNA-based Marks at the point-of-need

PREDICT

Principal Investigator(s):

Claudia Dos Santos

In Development

PREDICT

A multicentre evaluation of altered heart rate and respiratory rate variability to predict extubation failure (WAVE)

WAVE

Principal Investigator(s):

Andrew Seely

Enrolment Complete

WAVE

A National Survey of Neurocritical Care Medicine: Organizational Structure, Standards and Monitoring for Neurocritically Ill Patients within Canada

Principal Investigator(s):

Victoria McCredie, Alexis Turgeon

A point-of-care neurophysiological index of recovery from coma in the intensive care unit

Principal Investigator(s):

Stefanie Blain-Moraes, Catherine Duclos, Adrian Owen

A randomized controlled trial of family-partnered delirium prevention, detection, and management in critically ill adults: The ACTIVATE study

ACTIVATE

Principal Investigator(s):

Kirsten Fiest

Enrolling

ACTIVATE

A randomized trial of a complex respiratory intervention in acute traumatic spinal cord injury

Principal Investigator(s):

Jim Kutsogiannis

A Randomized Trial of Supplemental Parenteral Nutrition in Under and Over Weight Critically (TOP UP)

TOP UP

Principal Investigator(s):

Daren Heyland

TOP UP

A risk prediction tool to predict outcome in critically ill patients at time of tracheostomy insertion

Principal Investigator(s):

Jason Shahin

A Screening and Support Program for Bereaved Family Members in the ICU (ICU BEREAVE)

ICU BEREAVE

Principal Investigator(s):

James Downar

Enrolment Complete

ICU BEREAVE

A Survey of International Organ Donation Organizations on Pediatric Deceased Donation Practices

Principal Investigator(s):

Matthew Weiss

Enrolment Complete

A Trial to Determine Whether Septic Shock Reversal is Quicker in Pediatric Patients Randomized to an Early Goal Directed Fluid Sparing Strategy vs. Usual Care (SQUEEZE Trial)

SQUEEZE

Principal Investigator(s):

Melissa J Parker

Enrolment Complete

SQUEEZE

Access to Research in Community/Rural Hospitals Project (ARCH)

ARCH

Principal Investigator(s):

Jennifer Tsang

ARCH

Acute-on-chronic liver failure in Canadian Intensive Care Units: A period prevalence study

Principal Investigator(s):

Constantine Karvellas

Advancing Brain Outcomes in paediatric critically ill patients sedated with Volatile AnEsthestic Agents (ABOVE Trial)

ABOVE

Principal Investigator(s):

Angela Jerath, Nicole McKinnon, Rishi Ganesan, Marat Slessarev, Brian Cuthbertson

Enrolling

ABOVE

Age of Blood Evaluation Study: a Multicenter Randomized Clinical Trial (ABLE)

ABLE

Principal Investigator(s):

Jacques Lacroix, Paul Hébert, Dean Fergusson and Alan Tinmouth

Enrolment Complete

ABLE

Age of Blood in Children PICU (ABC PICU)

ABC PICU

Principal Investigator(s):

Marisa Tucci

Enrolment Complete

ABC PICU

Agitation, confusion, and aggression in critically ill traumatic brain injury (ACACIA Pilot)

ACACIA

Principal Investigator(s):

David Williamson

Enrolment Complete

ACACIA

ALbumin To Enhance Recovery from severe Acute Kidney Injury (ALTER-AKI)

ALTER-AKI

Principal Investigator(s):

Edward Clark

Enrolling

ALTER-AKI

Anemia in PICU Survivors

Principal Investigator(s):

Geneviève Du Pont-Thibodeau

In Development

Aneurysmal SubArachnoid Hemorrhage-Red Blood Cell Transfusion and Outcome Study (SAHaRA)

SAHaRA

Principal Investigator(s):

Shane English

Enrolling

SAHaRA

Anti-Thrombotic Therapy to Ameliorate Clinical Complications in Community Acquired Pneumonia (ATTACC-CAP )

ATTACC-CAP

Principal Investigator(s):

Ryan Zarychanski, Patrick Lawler, Alexis Turgeon, Sylvain Lother

In Development

ATTACC-CAP

Anti-Xa Guided Dosing of Low Molecular Weight Heparin for Prevention of Venous Thromboembolism Following Traumatic Injury: A Pilot Randomized Trial

Principal Investigator(s):

Alexandre Tran

In Development

Anticoagulation in COVID pneumonia (ATTACC)

ATTACC

Principal Investigator(s):

Ryan Zarychanski, Alexis Turgeon, Patrick Lawler, Ewan Goligher

Enrolment Complete

ATTACC

Find a Trial or Study

A Canadian Critical Care Knowledge Translation Network (aC3KTion Net)

PREcision meDIcine for CriTical care (PREDICT)-Power Blade: Early Sepsis Severity RNA-based Marks at the point-of-need

A multicentre evaluation of altered heart rate and respiratory rate variability to predict extubation failure (WAVE)

A National Survey of Neurocritical Care Medicine: Organizational Structure, Standards and Monitoring for Neurocritically Ill Patients within Canada

A point-of-care neurophysiological index of recovery from coma in the intensive care unit

A randomized controlled trial of family-partnered delirium prevention, detection, and management in critically ill adults: The ACTIVATE study

A randomized trial of a complex respiratory intervention in acute traumatic spinal cord injury

A Randomized Trial of Supplemental Parenteral Nutrition in Under and Over Weight Critically (TOP UP)

A risk prediction tool to predict outcome in critically ill patients at time of tracheostomy insertion

A Screening and Support Program for Bereaved Family Members in the ICU (ICU BEREAVE)

A Survey of International Organ Donation Organizations on Pediatric Deceased Donation Practices

A Trial to Determine Whether Septic Shock Reversal is Quicker in Pediatric Patients Randomized to an Early Goal Directed Fluid Sparing Strategy vs. Usual Care (SQUEEZE Trial)

Access to Research in Community/Rural Hospitals Project (ARCH)

Acute-on-chronic liver failure in Canadian Intensive Care Units: A period prevalence study

Advancing Brain Outcomes in paediatric critically ill patients sedated with Volatile AnEsthestic Agents (ABOVE Trial)

Age of Blood Evaluation Study: a Multicenter Randomized Clinical Trial (ABLE)

Age of Blood in Children PICU (ABC PICU)

Agitation, confusion, and aggression in critically ill traumatic brain injury (ACACIA Pilot)

ALbumin To Enhance Recovery from severe Acute Kidney Injury (ALTER-AKI)

Anemia in PICU Survivors

Aneurysmal SubArachnoid Hemorrhage-Red Blood Cell Transfusion and Outcome Study (SAHaRA)

Anti-Thrombotic Therapy to Ameliorate Clinical Complications in Community Acquired Pneumonia (ATTACC-CAP )

Anti-Xa Guided Dosing of Low Molecular Weight Heparin for Prevention of Venous Thromboembolism Following Traumatic Injury: A Pilot Randomized Trial

Anticoagulation in COVID pneumonia (ATTACC)