Trials and Studies - Canadian Critical Care Trials Group

New Consent Model: Launching Integrated Consent in Pediatric Pragmatic Research

Principal Investigator(s):

Saoirse Cameron

Non-Invasive ventilation and dexmedetomidine in critically ill adults Research Program (inDEX)

inDEX

Principal Investigator(s):

Kim Lewis

inDEX

Noninvasive Functional Biomarker for Early Detection and Continuous Monitoring of Microvascular Dysfunction

Principal Investigator(s):

Chris Ellis

Optimal Brain Oxygenation in Neurologic Intensive Care Unit (NeurO2 Trial)

NeurO2

Principal Investigator(s):

Alexis Turgeon, Shane English

NeurO2

Optimizing Transfusion Therapy in Critically-ill Children with Anemia (OpTTICCA): a large confirmatory international multicenter pragmatic parallel open-label non-inferiority SMART randomized controlled trial

OpTTICCA

Principal Investigator(s):

Marisa Tucci (Canada), Geneviève Du Pont-Thibodeau (Canada), Simon Stanworth (UK), Stéphane Leteurtre (Hôpital Jeanne de Flandre, Lille, France), Avishay Sarfatti (Oxford University Hospitals NHS Foundation Trust, Oxford, UK), Samiran Ray (GOSH, London, UK).

In Development

OpTTICCA

Optimizing Transfusion Thresholds in Critically-ill Children with Anaemia (P-OpTTICCA): a pilot trial for a large pragmatic international parallel open-label non-inferiority randomised controlled trial

P-OpTTICCA

Principal Investigator(s):

Jacques Lacroix, Marisa Tucci, Stéphane Leteurtre, Simon Stanworth

Enrolment Complete

P-OpTTICCA

OSCAR-ICU

Principal Investigator(s):

Han Ting Wang

Oscillation for ARDS Treated Early (OSCILLATE)

OSCILLATE

Principal Investigator(s):

Maureen Meade & Niall Ferguson

OSCILLATE

Paediatric intensive care stress ulcer prevention pilot trial (PIC-UP)

PIC-UP

Principal Investigator(s):

Mark Duffett

PIC-UP

Patient and Family-Centred Care of Potential Organ Donors in the ICU setting: Family Recommendations to Improve the Organ Donation Process

Principal Investigator(s):

Aimee Sarti

Enrolment Complete

Patient-centred and family-centred care of critically ill patients who are potential organ donors: a qualitative study protocol of family member perspectives

Principal Investigator(s):

Aimee Sarti

Enrolment Complete

Pediatric Post-Intensive Care Syndrome after critical illness

Principal Investigator(s):

Geneviève DuPont-Thibodeau

Pilot study for linking hemodynamic profiles of donors during withdrawal of life sustaining therapy to transplant outcomes in pediatric donation after cardio-circulatory death

Principal Investigator(s):

Sonny Dhanani

PIT-TBI

Principal Investigator(s):

François Lauzier

Plasma Transfusions in Critically Ill Children

Principal Investigator(s):

Oliver Karam

Enrolment Complete

PLEASe

Principal Investigator(s):

John Boyd

Predicting outcomes in pediatric disorders of consciousness

Principal Investigator(s):

Stefanie Blain-Moraes, Catherine Duclos

In Development

Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT)

PROSPECT

Principal Investigator(s):

Deborah Cook

Enrolment Complete

PROSPECT

Prognostic value of elevated troponins in critical illness (PRO-TROPICS)

PRO-TROPICS

Principal Investigator(s):

Emilie Belley-Côté

PRO-TROPICS

Program to Evaluate Deceased Organ Donation Programs with a Focus on Opt-Out Legislation in Nova Scotia (LEADDR)

LEADDR

Principal Investigator(s):

Matthew Weiss

LEADDR

Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation: The PROMIZING Study

PROMIZING

Principal Investigator(s):

Karen Bosma, Laurent Brochard

Enrolling

PROMIZING

Prospective cohort study on the evolution of procalcitonin and other infection markers in children with severe bacterial infections treated with antimicrobials

ATB PICU

Principal Investigator(s):

Patricia Fontela

Enrolling

ATB PICU

Proteomics in Pediatric Traumatic Brain Injury

Principal Investigator(s):

Jamie Hutchison

QBIct

Principal Investigator(s):

Anne-Marie Guerguerian

Find a Trial or Study

New Consent Model: Launching Integrated Consent in Pediatric Pragmatic Research

Non-Invasive ventilation and dexmedetomidine in critically ill adults Research Program (inDEX)

Noninvasive Functional Biomarker for Early Detection and Continuous Monitoring of Microvascular Dysfunction

Optimal Brain Oxygenation in Neurologic Intensive Care Unit (NeurO2 Trial)

Optimizing Transfusion Therapy in Critically-ill Children with Anemia (OpTTICCA): a large confirmatory international multicenter pragmatic parallel open-label non-inferiority SMART randomized controlled trial

Optimizing Transfusion Thresholds in Critically-ill Children with Anaemia (P-OpTTICCA): a pilot trial for a large pragmatic international parallel open-label non-inferiority randomised controlled trial

OSCAR-ICU

Oscillation for ARDS Treated Early (OSCILLATE)

Paediatric intensive care stress ulcer prevention pilot trial (PIC-UP)

Patient and Family-Centred Care of Potential Organ Donors in the ICU setting: Family Recommendations to Improve the Organ Donation Process

Patient-centred and family-centred care of critically ill patients who are potential organ donors: a qualitative study protocol of family member perspectives

Pediatric Post-Intensive Care Syndrome after critical illness

Pilot study for linking hemodynamic profiles of donors during withdrawal of life sustaining therapy to transplant outcomes in pediatric donation after cardio-circulatory death

PIT-TBI

Plasma Transfusions in Critically Ill Children

PLEASe

Predicting outcomes in pediatric disorders of consciousness

Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT)

Prognostic value of elevated troponins in critical illness (PRO-TROPICS)

Program to Evaluate Deceased Organ Donation Programs with a Focus on Opt-Out Legislation in Nova Scotia (LEADDR)

Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation: The PROMIZING Study

Prospective cohort study on the evolution of procalcitonin and other infection markers in children with severe bacterial infections treated with antimicrobials

Proteomics in Pediatric Traumatic Brain Injury

QBIct