Trials and Studies Page 7 - Canadian Critical Care Trials Group

National survey on the hemodynamic management of neurologically deceased organ donors

Principal Investigator(s):

Anne-Julie Frenette

Enrolment Complete

Neurodevelopment outcomes after PICU sedation

Principal Investigator(s):

Davinia Withington

Neurologic Physiology after Removal of Therapy study (NeuPaRT)

NeuPaRT

Principal Investigator(s):

Teneille Gofton, Marat Slessarev, Maureen Meade, Sonny Dhanani

Enrolling

NeuPaRT

NEUROlogically-impaired Extubation Timing Trial (NEURO-ETT)

NEURO-ETT

Principal Investigator(s):

Niall Ferguson, Damon Scales

NEURO-ETT

New Consent Model: Launching Integrated Consent in Pediatric Pragmatic Research

Principal Investigator(s):

Saoirse Cameron

Non-Invasive ventilation and dexmedetomidine in critically ill adults Research Program (inDEX)

inDEX

Principal Investigator(s):

Kim Lewis

inDEX

Noninvasive Functional Biomarker for Early Detection and Continuous Monitoring of Microvascular Dysfunction

Principal Investigator(s):

Chris Ellis

Optimal Brain Oxygenation in Neurologic Intensive Care Unit (NeurO2 Trial)

NeurO2

Principal Investigator(s):

Alexis Turgeon, Shane English

NeurO2

Optimizing Transfusion Therapy in Critically-ill Children with Anemia (OpTTICCA): a large confirmatory international multicenter pragmatic parallel open-label non-inferiority SMART randomized controlled trial

OpTTICCA

Principal Investigator(s):

Marisa Tucci (Canada), Geneviève Du Pont-Thibodeau (Canada), Simon Stanworth (UK), Stéphane Leteurtre (Hôpital Jeanne de Flandre, Lille, France), Avishay Sarfatti (Oxford University Hospitals NHS Foundation Trust, Oxford, UK), Samiran Ray (GOSH, London, UK).

In Development

OpTTICCA

Optimizing Transfusion Thresholds in Critically-ill Children with Anaemia (P-OpTTICCA): a pilot trial for a large pragmatic international parallel open-label non-inferiority randomised controlled trial

P-OpTTICCA

Principal Investigator(s):

Jacques Lacroix, Marisa Tucci, Stéphane Leteurtre, Simon Stanworth

Enrolment Complete

P-OpTTICCA

OSCAR-ICU

Principal Investigator(s):

Han Ting Wang

Oscillation for ARDS Treated Early (OSCILLATE)

OSCILLATE

Principal Investigator(s):

Maureen Meade & Niall Ferguson

OSCILLATE

Paediatric intensive care stress ulcer prevention pilot trial (PIC-UP)

PIC-UP

Principal Investigator(s):

Mark Duffett

PIC-UP

Patient and Family-Centred Care of Potential Organ Donors in the ICU setting: Family Recommendations to Improve the Organ Donation Process

Principal Investigator(s):

Aimee Sarti

Enrolment Complete

Patient-centred and family-centred care of critically ill patients who are potential organ donors: a qualitative study protocol of family member perspectives

Principal Investigator(s):

Aimee Sarti

Enrolment Complete

Pediatric Post-Intensive Care Syndrome after critical illness

Principal Investigator(s):

Geneviève DuPont-Thibodeau

Pilot study for linking hemodynamic profiles of donors during withdrawal of life sustaining therapy to transplant outcomes in pediatric donation after cardio-circulatory death

Principal Investigator(s):

Sonny Dhanani

PIT-TBI

Principal Investigator(s):

François Lauzier

Plasma Transfusions in Critically Ill Children

Principal Investigator(s):

Oliver Karam

Enrolment Complete

PLEASe

Principal Investigator(s):

John Boyd

Point Prevalence Study

CanPOINT

Principal Investigator(s):

François Lamontagne, Neill Adhikari

Enrolling

CanPOINT

Pragmatic mixed-methods randomized controlled trial of a followup care intervention for ICU survivors and caregivers (IMPACT-ICU)

IMPACT-ICU

Principal Investigator(s):

Tasha Jawa

IMPACT-ICU

Predicting outcomes in pediatric disorders of consciousness

Principal Investigator(s):

Stefanie Blain-Moraes, Catherine Duclos

In Development

Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT)

PROSPECT

Principal Investigator(s):

Deborah Cook

Enrolment Complete

PROSPECT

Find a Trial or Study

National survey on the hemodynamic management of neurologically deceased organ donors

Neurodevelopment outcomes after PICU sedation

Neurologic Physiology after Removal of Therapy study (NeuPaRT)

NEUROlogically-impaired Extubation Timing Trial (NEURO-ETT)

New Consent Model: Launching Integrated Consent in Pediatric Pragmatic Research

Non-Invasive ventilation and dexmedetomidine in critically ill adults Research Program (inDEX)

Noninvasive Functional Biomarker for Early Detection and Continuous Monitoring of Microvascular Dysfunction

Optimal Brain Oxygenation in Neurologic Intensive Care Unit (NeurO2 Trial)

Optimizing Transfusion Therapy in Critically-ill Children with Anemia (OpTTICCA): a large confirmatory international multicenter pragmatic parallel open-label non-inferiority SMART randomized controlled trial

Optimizing Transfusion Thresholds in Critically-ill Children with Anaemia (P-OpTTICCA): a pilot trial for a large pragmatic international parallel open-label non-inferiority randomised controlled trial

OSCAR-ICU

Oscillation for ARDS Treated Early (OSCILLATE)

Paediatric intensive care stress ulcer prevention pilot trial (PIC-UP)

Patient and Family-Centred Care of Potential Organ Donors in the ICU setting: Family Recommendations to Improve the Organ Donation Process

Patient-centred and family-centred care of critically ill patients who are potential organ donors: a qualitative study protocol of family member perspectives

Pediatric Post-Intensive Care Syndrome after critical illness

Pilot study for linking hemodynamic profiles of donors during withdrawal of life sustaining therapy to transplant outcomes in pediatric donation after cardio-circulatory death

PIT-TBI

Plasma Transfusions in Critically Ill Children

PLEASe

Point Prevalence Study

Pragmatic mixed-methods randomized controlled trial of a followup care intervention for ICU survivors and caregivers (IMPACT-ICU)

Predicting outcomes in pediatric disorders of consciousness

Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT)