Trials and Studies Page 5 - Canadian Critical Care Trials Group

Genetics of Mortality in Critical Care (GenOMICC)

GenOMICC

Principal Investigator(s):

David Maslove (Canadian study lead), Kenneth Baillie (PI)

Enrolment Complete

GenOMICC

Health-related quality-of-life and health-utility in critical care: validation of EQ-5D-5L patient and proxy tools & study of health-related quality-of-life in critically ill patient populations (QUICC EQ-5D)

QUICC EQ-5D

Principal Investigator(s):

Vincent Lau

Enrolling

QUICC EQ-5D

HEMOglobin transfusion threshold in Traumatic brain Injury OptimizatioN (HEMOTION Trial)

HEMOTION

Principal Investigator(s):

Alexis Turgeon, François Lauzier, Dean Fergusson

Enrolment Complete

HEMOTION

Heparin Anticoagulation to improve Outcomes in septic shock (HALO)

HALO

Principal Investigator(s):

Ryan Zarychanski, Dean Ferguson, and Anand Kumar

HALO

HNFO With or Without Helmet NIV for Oxygenation Support in Acute Respiratory Failure Trial (HONOUR)

HONOUR

Principal Investigator(s):

Damon Scales, Niall Ferguson

Enrolling

HONOUR

ICU Community Modeling and Artificial Intelligence to Improve Research Efficiency (ICU-Comma)

ICU-Comma

Principal Investigator(s):

Vincent Lau

Enrolment Complete

ICU-Comma

Identifying clinical subphenotypes in sepsis survivors with different epigenetic signatures and one-year outcomes

Principal Investigator(s):

Sabri Soussi

Enrolment Complete

Impact of permissive hypotension on end-organ damage in the elderly (OVATION/65)

OVATION/65

Principal Investigator(s):

François Lamontagne, Neill Adhikari, Elizabeth Wilcox

Enrolment Complete

OVATION/65

Implementation and impact of restricted family presence in the PICU during the COVID-19 pandemic

Principal Investigator(s):

Jennifer Foster

Enrolment Complete

Improvement of ventilatory support during pediatric non-invasive ventilation

Principal Investigator(s):

Guillaume Emeriaud

Improving Neurological Death Diagnosis Research Program

Principal Investigator(s):

Michaël Chassé

Improving Neurological Diagnostic Evaluation: A Canadian multicenter diagnostic test study

Principal Investigator(s):

Michaël Chassé, Jai Jai Shiva Shankar

Enrolment Complete

Improving Safety of Sedation Practice and Critical Illness Prognostication (SEVA)

SEVA

Principal Investigator(s):

Andrew J.E. Seely

Enrolment Complete

SEVA

INCOGNITO-AKI Program

INCOGNITO-AKI

Principal Investigator(s):

Gord Boyd

INCOGNITO-AKI

Increasing family engagement in critical care: The NGAGE Randomized Controlled Trial

NGAGE

Principal Investigator(s):

Michael Goldfarb

In Development

NGAGE

INDex CTP

INDex

Principal Investigator(s):

Michaël Chassé

Enrolment Complete

INDex

Inhalational anesthesia in the ICU: asthma, epilepsy, sedation

Principal Investigator(s):

Davinia Withington

inhaled Nitric Oxide for Cardiac Arrest in Pediatrics and Adults (iNOCAPA): A Pilot randomized controlled trial and translational biology study

iNOCAPA

Principal Investigator(s):

Jamie Hutchison, John Granton

Enrolling

iNOCAPA

Innovative methods to expand Canadian rehabilitation research infrastructure (CAN Measure)

CAN Measure

Principal Investigator(s):

Michelle Kho and Gord Boyd

CAN Measure

Inspiratory Muscle training in Patients Receiving Ongoing mechanical Ventilation (IMPROV)

IMPROV

Principal Investigator(s):

Georgiana Roman Sarita, Ewan Goligher, Dr. Dmitry Rozenberg

In Development

IMPROV

Intensive Care Unit Resident Scheduling Trial (InCURS)

InCURS

Principal Investigator(s):

Christopher Parshuram, Dominique Piquette

Enrolling

InCURS

Intra-abdominal hypertension

Principal Investigator(s):

Ian Ball

Enrolment Complete

Iron Therapy at Pediatric Intensive Care Discharge (IronKids)

IronKids

Principal Investigator(s):

Geneviève Du Pont-Thibodeau

In Development

IronKids

IV Acetaminophen After Cardiac Surgery Pilot Trial (IVACS)

IVACS

Principal Investigator(s):

Sheldon Magder

In Development

IVACS

Find a Trial or Study

Genetics of Mortality in Critical Care (GenOMICC)

Health-related quality-of-life and health-utility in critical care: validation of EQ-5D-5L patient and proxy tools & study of health-related quality-of-life in critically ill patient populations (QUICC EQ-5D)

HEMOglobin transfusion threshold in Traumatic brain Injury OptimizatioN (HEMOTION Trial)

Heparin Anticoagulation to improve Outcomes in septic shock (HALO)

HNFO With or Without Helmet NIV for Oxygenation Support in Acute Respiratory Failure Trial (HONOUR)

ICU Community Modeling and Artificial Intelligence to Improve Research Efficiency (ICU-Comma)

Identifying clinical subphenotypes in sepsis survivors with different epigenetic signatures and one-year outcomes

Impact of permissive hypotension on end-organ damage in the elderly (OVATION/65)

Implementation and impact of restricted family presence in the PICU during the COVID-19 pandemic

Improvement of ventilatory support during pediatric non-invasive ventilation

Improving Neurological Death Diagnosis Research Program

Improving Neurological Diagnostic Evaluation: A Canadian multicenter diagnostic test study

Improving Safety of Sedation Practice and Critical Illness Prognostication (SEVA)

INCOGNITO-AKI Program

Increasing family engagement in critical care: The NGAGE Randomized Controlled Trial

INDex CTP

Inhalational anesthesia in the ICU: asthma, epilepsy, sedation

inhaled Nitric Oxide for Cardiac Arrest in Pediatrics and Adults (iNOCAPA): A Pilot randomized controlled trial and translational biology study

Innovative methods to expand Canadian rehabilitation research infrastructure (CAN Measure)

Inspiratory Muscle training in Patients Receiving Ongoing mechanical Ventilation (IMPROV)

Intensive Care Unit Resident Scheduling Trial (InCURS)

Intra-abdominal hypertension

Iron Therapy at Pediatric Intensive Care Discharge (IronKids)

IV Acetaminophen After Cardiac Surgery Pilot Trial (IVACS)