Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT)
Principal Investigator(s):
Status:
Enrolment Complete
Please see publication: Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients: A Randomized Clinical Trial
Among critically ill patients requiring mechanical ventilation, administration of the probiotic L rhamnosus GG compared with placebo, resulted in no significant difference in the development of ventilator-associated pneumonia. These findings do not support the use of L rhamnosus GG in critically ill patients.
Source: JAMA
Diagram: Probiotics in ICU Research Program (click to expand)
Coordinators:
Co-investigators:
Maureen Meade, Timothy Kirachi, John Marshall, Jan Friedrich, Peter Dodek, Geeta Mehta, François Lauzier, Lauralyn McIntyre, Joe Pagliarello, Bill Henderson, Margaret Herridge