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Nicole  Zytaruk
Senior Research Associate / Nurse
McMaster University / St Joseph's Healthcare Hamilton
Research Focus:
Prevention of ICU-acquired complications

Nicole Zytaruk

Research Coordinators Group (CCCRCG)

Nicole Zytaruk is a Senior Research Associate and Project Manager based at St. Joseph’s Healthcare Hamilton with McMaster University.  For the past 26 years she has been overseeing research projects in Critical Care Research within the CLARITY - Clinical Advancements through Research and Information Technology group.  Her research interests include prevention of ICU-acquired complications such as stress ulcer gastric bleeding, deep venous thrombosis and pneumonia along with improving and personalizing end-of-life care.  Currently she is serving on the CCCTG Board of Governors as the Scientific Meeting Director.  Also, having served previously as the Chair for the Canadian Critical Care Research Coordinators Group, she has assisted in the creation and dissemination of many tools, study aids and standardized operating plans for other Research Coordinators in Critical Care.  Most recently, Nicole has managed 4 large international randomized control trials overseen by Health Canada with Clinical Trial Applications.  Her publications total 51 peer-review articles and 96 abstracts.

Recent work

  1. Cook DJ, Meade M, Guyatt G, Walter SD, Heels-Ansdell D, Warkentin T, Zytaruk N, Crowther MA, Geerts W, Cooper DJ, Vallance S, Qushmaq I, Rocha M, Berwanger O, Vlahakis N (Writing Committee) for the PROTECT (Prophylaxis for ThromboEmbolism in Critical Care Trial) Investigators for the Canadian Critical Care Trials Group & the Australian and New Zealand Intensive Care Society Clinical Trials Group.  A Randomized Trial of Dalteparin versus Unfractionated Heparin in Critically Ill Patients. N Engl J Med 2011;364(14):1305-1314.
  2. Johnstone J, Meade M, Lauzier F, Marshall J, Duan E, Dionne J, Arabi Y, Heels-Ansdell D, Thabane L, Lamarche D, Surette M, Zytaruk N, Mehta S, Dodek P, McIntyre L, English S, Rochwerg B, Karachi T, Henderson W, Wood G, Ovakim D, Herridge M, Granton J, Wilcox ME, Goffi A, Stelfox HT, Niven D, Muscedere J, Lamontagne F, D’Aragon F, St.-Arnaud C, Ball I, Nagpal D, Girard M, Aslanian P, Charbonney  E, Williamson D, Sligl W, Friedrich J, Adhikari NK, Marquis F, Archambault P, Khwaja K, Kristof A, Kutsogiannis J, Zarychanski R, Paunovic B, Reeve B, Lellouche F, Hosek P, Tsang J, Binnie A, Trop S, Loubani O, Hall R, Cirone R, Reynolds S, Lysecki P, Golan E, Cartin-Ceba R, Taylor R, Cook D, For The PROSPECT Investigators and The Canadian Critical Care Trials Group. Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients: A Randomized Clinical Trial. 2021;326(11):1024-1033. doi:10.1001/jama.2021.13355
  3. Principles Guiding Non-Pandemic Critical Care Research during a Pandemic, Cook D, Kho M, Duan E, Alhazzani W, Takaoka A, Clarke F, Zytaruk N, Vanstone M. Crit Care Med 2020;48(10)1403-1410.   CCMED DOI: 10.1097/CCM.0000000000004538
  4. Stressors for Canadian Research Coordinators in Critical Care: The MOTIVAE Survey, McDonald E, Zytaruk N, Heels-Ansdell D, Smith O, Borges D, Hand L, Clarke F, Nassar A, Bennardo M, Cook D for the Canadian Critical Care Research Coordinators’ Group Am J Crit Care (2020) 29 (1): 41-48.
  5. Vanstone M, Toledo F, Clarke F, Boyle A, Giacomini M, Swinton M, Saunders L, Shears M, Zytaruk N, Woods A, Rose T, Hand-Breckenridge T, Heels-Ansdell D, Anderson-White S, Sheppard R, Cook DJ. Narrative Medicine and Death in the ICU: Word Clouds as a Visual Legac BMJ Supportive & Palliative Care 2016;0:1–8. doi:10.1136/bmjspcare-2016-001179.