Publications

O'Hearn K, McNally D, Choong K, Acharya A, Wong HR, Lawson M, Ramsay T, McIntyre L, Gilfoyle E, Tucci M, Wensley D, Gottesman R, Morrison G, Menon K; Canadian Critical Care Trials Group. Steroids in fluid and/or vasoactive infusion dependent pediatric shock: study protocol for a randomized controlled trial. Trials. 2016 May 6;17(1):238. PMID: 27153945

Cameron JI, Chu LM, Matte A, Tomlinson G, Chan L, Thomas C, Friedrich JO, Mehta S, Lamontagne F, Levasseur M, Ferguson ND, Adhikari NK, Rudkowski JC, Meggison H, Skrobik Y, Flannery J, Bayley M, Batt J, dos Santos C, Abbey SE, Tan A, Lo V, Mathur S, Parotto M, Morris D, Flockhart L, Fan E, Lee CM, Wilcox ME, Ayas N, Choong K, Fowler R, Scales DC, Sinuff T, Cuthbertson BH, Rose L, Robles P, Burns S, Cypel M, Singer L, Chaparro C, Chow CW, Keshavjee S, Brochard L, Hébert P, Slutsky AS, Marshall JC, Cook D, Herridge MS; RECOVER Program Investigators (Phase 1: towards RECOVER); Canadian Critical Care Trials Group. One-Year Outcomes in Caregivers of Critically Ill Patients. N Engl J Med. 2016 May 12;374(19):1831-41. PMID: 27168433 

Wilkinson AA, Simic N, Frndova H, Taylor MJ, Choong K, Fraser D, Campbell C, Dhanani S, Kuehn S, Beauchamp MH, Farrell C, Anderson V, Guerguerian AM, Dennis M, Schachar R, Hutchison JS; Attention and Traumatic Brain Injury Investigators, the Canadian Critical Care Trials Group, and the Canadian Critical Care Translational Biology Group. Serum Biomarkers Help Predict Attention Problems in Critically Ill Children With Traumatic Brain Injury. Pediatr Crit Care Med. 2016 Jul;17(7):638-48. PMID: 27167007

McIntyre L, Rowe BH, Walsh TS, Gray A, Arabi Y, Perner A, Gordon A, Marshall J, Cook D, Fox-Robichaud A, Bagshaw SM, Green R, Schweitzer I, Turgeon A, Zarychanski R, English S, Chassé M, Stiell I, Fergusson D; Canadian Critical Care Trials Group. Multicountry survey of emergency and critical care medicine physicians' fluid resuscitation practices for adult patients with early septic shock. BMJ Open. 2016 Jul 7;6(7). PMID: 27388345

Li G, Cook DJ, Thabane L, Friedrich JO, Crozier TM, Muscedere J, Granton J, Mehta S, Reynolds SC, Lopes RD, Francois L, Freitag AP, Levine MA; PROTECT Investigators for the Canadian Critical Care Trials Group, and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Risk factors for mortality in patients admitted to intensive care units with pneumonia. Respir Res. 2016 Jul 11;17(1):80. PMID: 27401184

Guerra GG, Joffe AR, Cave D, Duff J, Duncan S, Sheppard C, Tawfik G, Hartling L, Jou H, Vohra S; Sedation Withdrawal and Analgesia Team, and the Canadian Critical Care Trials Group. Survey of Sedation and Analgesia Practice Among Canadian Pediatric Critical Care Physicians. Pediatr Crit Care Med. 2016 Sep;17(9):823-30. PMID: 27467012

Cook DJ, Johnstone J, Marshall JC, Lauzier F, Thabane L, Mehta S, Dodek PM, McIntyre L, Pagliarello J, Henderson W, Taylor RW, Cartin-Ceba R, Golan E, Herridge M, Wood G, Ovakim D, Karachi T, Surette MG, Bowdish DM, Lamarche D, Verschoor CP, Duan EH, Heels-Ansdell D, Arabi Y, Meade M; PROSPECT Investigators and the Canadian Critical Care Trials Group. Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial-PROSPECT: a pilot trial. Trials. 2016 Aug 2;17:377. PMID: 27480757

Mehta S, Meade M, Burry L, Mallick R, Katsios C, Fergusson D, Dodek P, Burns K, Herridge M, Devlin JW, Tanios M, Fowler R, Jacka M, Skrobik Y, Olafson K, Cook D; SLEAP Investigators and the Canadian Critical Care Trials Group. Variation in diurnal sedation in mechanically ventilated patients who are managed with a sedation protocol alone or a sedation protocol and daily interruption. Crit Care. 2016 Aug 1;20(1):233. PMID: 27480314

Jain S, Menon K, Piquette D, Gottesman R, Hutchison J, Gilfoyle E, Group CC. The Development of a Critical Care Resident Research Curriculum: A Needs Assessment. Can Respir J. 2016; Epub 2016 Aug 16. PMID: 27610029

Parker MJ, Thabane L, Fox-Robichaud A, Liaw P, Choong K; Canadian Critical Care Trials Group and the Canadian Critical Care Translational Biology Group.A trial to determine whether septic shock-reversal is quicker in pediatric patients randomized to an early goal-directed fluid-sparing strategy versus usual care (SQUEEZE): study protocol for a pilot randomized controlled trial. Trials. 2016 Nov 22;17(1):556. PMID: 27876084

English SW, Fergusson D, Chassé M, Turgeon AF, Lauzier F, Griesdale D, Algird A, Kramer A, Tinmouth A, Lum C, Sinclair J, Marshall S, Dowlatshahi D, Boutin A, Pagliarello G, McIntyre LA; Canadian Critical Care Trials Group. Aneurysmal SubArachnoid Hemorrhage-Red Blood Cell Transfusion And Outcome (SAHaRA): a pilot randomised controlled trial protocol. BMJ Open. 2016 Dec 7;6(12):e012623. PMID: 27927658

Savage RD, Fowler RA, Rishu AH, Bagshaw SM, Cook D, Dodek P, Hall R, Kumar A, Lamontagne F, Lauzier F, Marshall J, Martin CM, McIntyre L, Muscedere J, Reynolds S, Stelfox HT, Daneman N. The Effect of Inadequate Initial Empiric Antimicrobial Treatment on Mortality in Critically Ill Patients with Bloodstream Infections: A Multi-Centre Retrospective Cohort Study. PLoS One. 2016 May 6;11(5):e0154944. PMID:27152615

Kho ME, Molloy AJ, Clarke FJ, Ajami D, McCaughan M, Obrovac K, Murphy C, Camposilvan L, Herridge MS, Koo KK, Rudkowski J, Seely AJ, Zanni JM, Mourtzakis M, Piraino T, Cook DJ; Canadian Critical Care Trials Group.TryCYCLE: A Prospective Study of the Safety and Feasibility of Early In-Bed Cycling in Mechanically Ventilated Patients. PLoS One. 2016 Dec 28;11(12). PMID: 28030555

Alhazzani W, Guyatt G, Marshall JC, Hall R, Muscedere J, Lauzier F, Thabane L, Alshahrani M, English SW, Arabi YM, Deane AM, Karachi T, Rochwerg B, Finfer S, Daneman N, Zytaruk N, Heel-Ansdell D, Cook D, Of OB. Re-evaluating the Inhibition of Stress Erosions (REVISE): a protocol for pilot randomized controlled trial. Ann Saudi Med. 2016 Nov-Dec;36(6):427-433. PMID: 27920416

Herridge MS, Chu LM, Matte A, Tomlinson G, Chan L, Thomas C, Friedrich JO, Mehta S, Lamontagne F, Levasseur M, Ferguson ND, Adhikari NK, Rudkowski JC, Meggison H, Skrobik Y, Flannery J, Bayley M, Batt J, Dos Santos C, Abbey SE, Tan A, Lo V, Mathur S, Parotto M, Morris D, Flockhart L, Fan E, Lee CM, Wilcox ME, Ayas N, Choong K, Fowler R, Scales DC, Sinuff T, Cuthbertson BH, Rose L, Robles P, Burns S, Cypel M, Singer L, Chaparro C, Chow CW, Keshavjee S, Brochard L, Hebert P, Slutsky AS, Marshall JC, Cook D, Cameron JI; RECOVER Program Investigators (Phase 1: towards RECOVER) and the Canadian Critical Care Trials Group. The RECOVER Program: Disability Risk Groups & One Year Outcome after ≥ 7 Days of Mechanical Ventilation. Am J Respir Crit Care Med. 2016 Mar 14. [Epub ahead of print] PMID: 26974173

Koo KK, Choong K, Cook DJ, Herridge M, Newman A, Lo V, Guyatt G, Priestap F, Campbell E, Burns KE, Lamontagne F, Meade MO; Canadian Critical Care Trials Group. Early mobilization of critically ill adults: a survey of knowledge, perceptions and practices of Canadian physicians and physiotherapists. CMAJ Open. 2016 Aug 18;4(3):E448-E454. PMID: 27730109

Fléchelles, O, Brissaud, O, Fowler, R, Ducruet, T, Jouvet, P. The Pediatric Canadian Critical Care Trials Group H1N1 Collaborative and Groupe Francophone de Réanimation et Urgences Pédiatriques. Pandemic influenza 2009: Impact of vaccination coverage on critical illness in children, a Canada and France observational study. World J Clin Pediatr 2016 November 8; 5(4): 374-382

Rose L, Burry L, Mallick R, Luk E, Cook DJ, Fergusson ND, Meade M, Herridge M, Dodek PE, Burns KE, Granton J, Ferguson ND, Devlin J, Steinberg M, Keenan S, Reynolds S, Tanios M, Fowler R, Jacka M, Olafson K, Skrobik Y, Mehta S for the SLEAP investigators and Canadian Critical Care Trials Group. Prevalence, risk factors and outcomes associated with physical restraint use in mechanically ventilated adults. J Crit Care. 2016 Feb;31(1):31-5.

Mehta S, Cook D, Devlin JW, Skrobik Y, Meade M, Fergusson D, Herridge M, Steinberg M, Granton J, Ferguson N, Tanios M, Dodek P, Fowler R, Burns K, Jacka M, Olafson K, Mallick R, Reynolds S, Keenan S, Burry L; for the SLEAP Investigators and the Canadian Critical Care Trials Group. Prevalence, Risk Factors, and Outcomes of Delirium in Mechanically Ventilated Adults.Crit Care Med. 2015, 43(3):557-66. PMID: 25493968

Lim W, Meade M, Lauzier F, Zarychanski R, Mehta S, Lamontagne F, Dodek P, McIntyre L, Hall R, Heels-Ansdell D, Fowler R, Pai M, Guyatt G, Crowther MA, Warkentin TE, Devereaux PJ, Walter SD, Muscedere J, Herridge M, Turgeon AF, Geerts W, Finfer S, Jacka M, Berwanger O, Ostermann M, Qushmaq I, Friedrich JO, Cook DJ; for the PROphylaxis for ThromboEmbolism in Critical Care Trial Investigators, the Canadian Critical Care Trials Group, and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Failure of Anticoagulant Thromboprophylaxis: Risk Factors in Medical-Surgical Critically Ill Patients.Crit Care Med. 2015; 43(2):401-10. PMID: 25474533

Downar J, You JJ, Bagshaw SM, Golan E, Lamontagne F, Burns K, Sridhar SK, Seely A, Meade MO, Fox-Robichaud A, Cook D, Turgeon AF, Dodek P, Xiong W, Fowler R; on behalf of the Canadian Critical Care Trials Group.Nonbeneficial Treatment Canada: Definitions, Causes, and Potential Solutions From the Perspective of Healthcare Practitioners.Crit Care Med. 2015 43(2):270-81. PMID: 25377017

Rose L, Fitzgerald E, Cook D, Kim S, Steinberg M, Devlin JW, Ashley BJ, Dodek P, Smith O, Poretta K, Lee Y, Burns K, Harvey J, Skrobik Y, Fergusson D, Meade M, Kraguljac A, Burry L, Mehta S; SLEAP Investigators and the Canadian Critical Care Trials Group.Clinician perspectives on protocols designed to minimize sedation.J Crit Care. 30(2):348-52. PMID: 25466317

Cook DJ, Ferguson ND, Hand L, Austin P, Zhou Q, Adhikari NK, Danesh V, Arabi Y, Matte AL, Clarke FE, Mehta S, Smith O, Wise MP, Friedrich JO, Keenan SP, Hanna S, Meade MO; for the OSCILLation for ARDS Treated Early Investigators and the Canadian Critical Care Trials Group.Coenrollment in a Randomized Trial of High-Frequency Oscillation: Prevalence, Patterns, Predictors, and Outcomes. Crit Care Med. 2015 Feb;43(2):328-38 PMID: 25393702

Choong K, Al-Harbi S, Siu K, Wong K, Cheng J, Baird B, Pogorzelski D, Timmons B, Gorter JW, Thabane L, Khetani M; on behalf of the Canadian Critical Care Trials Group.Functional Recovery Following Critical Illness in Children: The "Wee-Cover" Pilot Study. Pediatr Crit Care Med. 2015 May;16(4):310-8. PMID: 25651047