Publications

Parker MJ, Thabane L, Fox-Robichaud A, Liaw P, Choong K; Canadian Critical Care Trials Group and the Canadian Critical Care Translational Biology Group.A trial to determine whether septic shock-reversal is quicker in pediatric patients randomized to an early goal-directed fluid-sparing strategy versus usual care (SQUEEZE): study protocol for a pilot randomized controlled trial. Trials. 2016 Nov 22;17(1):556. PMID: 27876084

English SW, Fergusson D, Chassé M, Turgeon AF, Lauzier F, Griesdale D, Algird A, Kramer A, Tinmouth A, Lum C, Sinclair J, Marshall S, Dowlatshahi D, Boutin A, Pagliarello G, McIntyre LA; Canadian Critical Care Trials Group. Aneurysmal SubArachnoid Hemorrhage-Red Blood Cell Transfusion And Outcome (SAHaRA): a pilot randomised controlled trial protocol. BMJ Open. 2016 Dec 7;6(12):e012623. PMID: 27927658

Savage RD, Fowler RA, Rishu AH, Bagshaw SM, Cook D, Dodek P, Hall R, Kumar A, Lamontagne F, Lauzier F, Marshall J, Martin CM, McIntyre L, Muscedere J, Reynolds S, Stelfox HT, Daneman N. The Effect of Inadequate Initial Empiric Antimicrobial Treatment on Mortality in Critically Ill Patients with Bloodstream Infections: A Multi-Centre Retrospective Cohort Study. PLoS One. 2016 May 6;11(5):e0154944. PMID:27152615

Kho ME, Molloy AJ, Clarke FJ, Ajami D, McCaughan M, Obrovac K, Murphy C, Camposilvan L, Herridge MS, Koo KK, Rudkowski J, Seely AJ, Zanni JM, Mourtzakis M, Piraino T, Cook DJ; Canadian Critical Care Trials Group.TryCYCLE: A Prospective Study of the Safety and Feasibility of Early In-Bed Cycling in Mechanically Ventilated Patients. PLoS One. 2016 Dec 28;11(12). PMID: 28030555

Alhazzani W, Guyatt G, Marshall JC, Hall R, Muscedere J, Lauzier F, Thabane L, Alshahrani M, English SW, Arabi YM, Deane AM, Karachi T, Rochwerg B, Finfer S, Daneman N, Zytaruk N, Heel-Ansdell D, Cook D, Of OB. Re-evaluating the Inhibition of Stress Erosions (REVISE): a protocol for pilot randomized controlled trial. Ann Saudi Med. 2016 Nov-Dec;36(6):427-433. PMID: 27920416

Herridge MS, Chu LM, Matte A, Tomlinson G, Chan L, Thomas C, Friedrich JO, Mehta S, Lamontagne F, Levasseur M, Ferguson ND, Adhikari NK, Rudkowski JC, Meggison H, Skrobik Y, Flannery J, Bayley M, Batt J, Dos Santos C, Abbey SE, Tan A, Lo V, Mathur S, Parotto M, Morris D, Flockhart L, Fan E, Lee CM, Wilcox ME, Ayas N, Choong K, Fowler R, Scales DC, Sinuff T, Cuthbertson BH, Rose L, Robles P, Burns S, Cypel M, Singer L, Chaparro C, Chow CW, Keshavjee S, Brochard L, Hebert P, Slutsky AS, Marshall JC, Cook D, Cameron JI; RECOVER Program Investigators (Phase 1: towards RECOVER) and the Canadian Critical Care Trials Group. The RECOVER Program: Disability Risk Groups & One Year Outcome after ≥ 7 Days of Mechanical Ventilation. Am J Respir Crit Care Med. 2016 Mar 14. [Epub ahead of print] PMID: 26974173

Koo KK, Choong K, Cook DJ, Herridge M, Newman A, Lo V, Guyatt G, Priestap F, Campbell E, Burns KE, Lamontagne F, Meade MO; Canadian Critical Care Trials Group. Early mobilization of critically ill adults: a survey of knowledge, perceptions and practices of Canadian physicians and physiotherapists. CMAJ Open. 2016 Aug 18;4(3):E448-E454. PMID: 27730109

Fléchelles, O, Brissaud, O, Fowler, R, Ducruet, T, Jouvet, P. The Pediatric Canadian Critical Care Trials Group H1N1 Collaborative and Groupe Francophone de Réanimation et Urgences Pédiatriques. Pandemic influenza 2009: Impact of vaccination coverage on critical illness in children, a Canada and France observational study. World J Clin Pediatr 2016 November 8; 5(4): 374-382

Rose L, Burry L, Mallick R, Luk E, Cook DJ, Fergusson ND, Meade M, Herridge M, Dodek PE, Burns KE, Granton J, Ferguson ND, Devlin J, Steinberg M, Keenan S, Reynolds S, Tanios M, Fowler R, Jacka M, Olafson K, Skrobik Y, Mehta S for the SLEAP investigators and Canadian Critical Care Trials Group. Prevalence, risk factors and outcomes associated with physical restraint use in mechanically ventilated adults. J Crit Care. 2016 Feb;31(1):31-5.

Mehta S, Cook D, Devlin JW, Skrobik Y, Meade M, Fergusson D, Herridge M, Steinberg M, Granton J, Ferguson N, Tanios M, Dodek P, Fowler R, Burns K, Jacka M, Olafson K, Mallick R, Reynolds S, Keenan S, Burry L; for the SLEAP Investigators and the Canadian Critical Care Trials Group. Prevalence, Risk Factors, and Outcomes of Delirium in Mechanically Ventilated Adults.Crit Care Med. 2015, 43(3):557-66. PMID: 25493968

Lim W, Meade M, Lauzier F, Zarychanski R, Mehta S, Lamontagne F, Dodek P, McIntyre L, Hall R, Heels-Ansdell D, Fowler R, Pai M, Guyatt G, Crowther MA, Warkentin TE, Devereaux PJ, Walter SD, Muscedere J, Herridge M, Turgeon AF, Geerts W, Finfer S, Jacka M, Berwanger O, Ostermann M, Qushmaq I, Friedrich JO, Cook DJ; for the PROphylaxis for ThromboEmbolism in Critical Care Trial Investigators, the Canadian Critical Care Trials Group, and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Failure of Anticoagulant Thromboprophylaxis: Risk Factors in Medical-Surgical Critically Ill Patients.Crit Care Med. 2015; 43(2):401-10. PMID: 25474533

Downar J, You JJ, Bagshaw SM, Golan E, Lamontagne F, Burns K, Sridhar SK, Seely A, Meade MO, Fox-Robichaud A, Cook D, Turgeon AF, Dodek P, Xiong W, Fowler R; on behalf of the Canadian Critical Care Trials Group.Nonbeneficial Treatment Canada: Definitions, Causes, and Potential Solutions From the Perspective of Healthcare Practitioners.Crit Care Med. 2015 43(2):270-81. PMID: 25377017

Rose L, Fitzgerald E, Cook D, Kim S, Steinberg M, Devlin JW, Ashley BJ, Dodek P, Smith O, Poretta K, Lee Y, Burns K, Harvey J, Skrobik Y, Fergusson D, Meade M, Kraguljac A, Burry L, Mehta S; SLEAP Investigators and the Canadian Critical Care Trials Group.Clinician perspectives on protocols designed to minimize sedation.J Crit Care. 30(2):348-52. PMID: 25466317

Cook DJ, Ferguson ND, Hand L, Austin P, Zhou Q, Adhikari NK, Danesh V, Arabi Y, Matte AL, Clarke FE, Mehta S, Smith O, Wise MP, Friedrich JO, Keenan SP, Hanna S, Meade MO; for the OSCILLation for ARDS Treated Early Investigators and the Canadian Critical Care Trials Group.Coenrollment in a Randomized Trial of High-Frequency Oscillation: Prevalence, Patterns, Predictors, and Outcomes. Crit Care Med. 2015 Feb;43(2):328-38 PMID: 25393702

Choong K, Al-Harbi S, Siu K, Wong K, Cheng J, Baird B, Pogorzelski D, Timmons B, Gorter JW, Thabane L, Khetani M; on behalf of the Canadian Critical Care Trials Group.Functional Recovery Following Critical Illness in Children: The "Wee-Cover" Pilot Study. Pediatr Crit Care Med. 2015 May;16(4):310-8. PMID: 25651047

Heyland DK, Dodek P, Mehta S, Cook D, Garland A, Stelfox HT, Bagshaw SM, Kutsogiannis DJ, Burns K, Muscedere J, Turgeon AF, Fowler R, Jiang X, Day AG; on behalf of the Canadian Critical Care Trials Group and the Canadian Researchers at the End of Life Network (CARENET).Admission of the very elderly to the intensive care unit: Family members' perspectives on clinical decision-making from a multicenter cohort study. Palliat Med. 2015 Apr;29(4):324-35. PMID: 25645668

Burns KEA, Rizvi L, Smith O, Lee Y, Lee J, Wang M, Brown M, Parker M, Premji A, Leung D, Hammond Mobilio M, Gotlib-Conn L, Nisenbaum R, Santos M, Li Y,  Mehta S.  Is There a Role for Physician Involvement in Introducing Research to Surrogate Decision Makers in the Intensive Care Unit? (The Approach Trial: A Mixed Methods Study) Intensive Care Med 2015;41:58-67. PMID: 25491659

Stelfox H, Lane D, Boyd J, Taylor S, Perrier L, Straus S, Zygun D, Zuege D. A Scoping Review of Patient Discharge from Intensive Care: Opportunities and Tools to Improve Care. Chest. 2015;147(2):317-27. PMID: 25210942

Li P, Boyd JM, Ghali WA, Stelfox HT. Stakeholder Views regarding Patient Discharge from Intensive Care: Suboptimal Quality and Opportunities for Improvement. Can Respir J. 2015, 22(2):115-4. PMID: 25522304

Archambault PM, Turgeon AF, Witteman HO, Lauzier F, Moore L, Lamontagne F, Horsley T, Gagnon M-P, Droit A, Weiss M, Tremblay S, Lachaine J, Le Sage N, Émond M, Berthelot S, Plaisance A, Lapointe J, Razek T, van de Belt TH, Brand K, Bérubé M, Clément J, Grajales FJ, Eysenbach G, Kuziemsky  G, Friedman D, Lang E, Muscedere J, Rizoli S, Roberts DJ, Scales DC, Sinuff T, Stelfox HT, Gagnon I, Chabot C, Grenier R, Légaré F, Canadian Critical Care Trials Group. Implementation and Evaluation of a Wiki Involving Multiple Stakeholders Including Patients in the Promotion of Best Practices in Trauma Care:The WikiTrauma Interrupted Time Series Protocol. JMIR Res Protoc 2015,4(1): e21p.2.

Zarychanski R, Abou-Setta AM, Kanji S, Turgeon AF, Kumar A, Houston DS, Rimmer E, Houston BL, McIntyre L, Fox-Robichaud AE, Hébert P, Cook DJ, Fergusson DA, for the Canadian Critical Care Trials Group.  The efficacy and safety of heparin in patients with sepsis: A systematic review and meta-analysis.  Critical Care Medicine. 2015;43(3):511-8.  PMID:25493972

Czerwonka AI, Herridge MS, Chan L, Chu LM, Matte A, Cameron JI. Changing support needs of survivors of complex critical illness and their family caregivers across the care continuum: A qualitative pilot study of Towards RECOVER. J Crit Care. 2015;30(2):242-9. PMID: 25466314

Lacroix, J, Hébert, PC, Fergusson, DA, Tinmouth, A, Cook, DJ, Marshall, JC, Clayton, L, McIntyre, L, Callum, J, Turgeon, AF, Blajchman, MA, Walsh, TS, Stanworth, SJ, Campbell, H, Capellier, G, Tiberghien, P, Bardiaux, L, van de Watering, L, van der Meer, NJ, Sabri, E, Vo, D for the ABLE Investigators and the Canadian Critical Care Trials Group. Age of Transfused Blood in Critically Ill Adults.N Engl J Med. 2015, 372(15):1410-8. PMID: 25776801

Parshuram CS, Amaral AC, Ferguson ND, Baker GR, Etchells EE, Flintoft V, Granton J, Lingard L, Kirpalani H, Mehta S, Moldofsky H, Scales DC, Stewart TE, Willan AR, Friedrich JO; Canadian Critical Care Trials Group. Patient safety, resident well-being and continuity of care with different resident duty schedules in the intensive care unit: a randomized trial. CMAJ. 2015 Mar 17;187(5):321-9. PMID: 25667258