Publications

Choong K, Fraser DD, Al-Farsi A, Awlad Thani S, Cameron S, Clark H, Cuello C, Debigaré S, Ewusie J, Kennedy K, Kho ME, Krasevich K, Martin CM, Thabane L, Nanji J, Watts C, Simpson A, Todt A, Wong J, Xie F, Vu M, Cupido C; Canadian Critical Care Trials Group. Early Rehabilitation in Critically ill Children: A Two Center Implementation Study. Pediatr Crit Care Med. 2024 Feb 1;25(2):92-105. doi: 10.1097/PCC.0000000000003343. Epub 2024 Jan 19. PMID: 38240534.

Choong K, Fraser DD, Cameron S, Cuello C, Debigaré S, Ewusie J, Kho ME, Krasevich K, Martin CM, Thabane L, Todt A, Cupido C; Canadian Critical Care Trials Group. Post-Intensive Care Sequelae in Pediatrics-Results of an Early Rehabilitation Implementation Study. Pediatr Crit Care Med. 2024 Feb 2. doi: 10.1097/PCC.0000000000003467. Epub ahead of print. PMID: 38305699.

Vanstone MG, Krewulak K, Taneja S, Swinton M, Fiest K, Burns KEA, Debigare S, Dionne JC, Guyatt G, Marshall JC, Muscedere JG, Deane AM, Finfer S, Myburgh JA, Gouskos A, Rochwerg B, Ball I, Mele T, Niven DJ, English SW, Verhovsek M, Cook DJ; Canadian Critical Care Trials Group. Patient-important upper gastrointestinal bleeding in the ICU: A mixed-methods study of patient and family perspectives. J Crit Care. 2024 Mar 5;81:154761. doi: 10.1016/j.jcrc.2024.154761. Epub ahead of print. PMID: 38447306.

Cook D, Deane A, Dionne JC, Lauzier F, Marshall JC, Arabi YM, Wilcox ME, Ostermann M, Al-Fares A, Heels-Ansdell D, Zytaruk N, Thabane L, Finfer S; REVISE Investigators and the Canadian Critical Care Trials Group. Adjudication of a primary trial outcome: Results of a calibration exercise and protocol for a large international trial. Contemp Clin Trials Commun. 2024 Mar 5;39:101284. doi: 10.1016/j.conctc.2024.101284. PMID: 38559746; PMCID: PMC10979133.

Muscedere J, Bagshaw SM, Kho M, Mehta S, Cook DJ, Boyd JG, Sibley S, Wang HT, Archambault PM, Albert M, Rewa OG, Ball I, Norman PA, Day AG, Hunt M, Loubani O, Mele T, Sarti AJ, Shahin J; Canadian Critical Care Trials Group. Frailty, Outcomes, Recovery and Care Steps of Critically Ill Patients (FORECAST): a prospective, multi-centre, cohort study. Intensive Care Med. 2024 May 15. doi: 10.1007/s00134-024-07404-9. Epub ahead of print. PMID: 38748266.

Cani E, Tsang JLY, Binnie A, Dos Santos CC, Fowler R, Lamontagne F, Mehta S, Liaw PC; Canadian Critical Care Translational Biology Group (CCCTBG), and the Canadian Critical Care Trials Group (CCCTG). Barriers to participation in biosampling-based translational research: A cross-sectional survey of Canadian critical care researchers. PLoS One. 2024 May 17;19(5):e0303304. doi: 10.1371/journal.pone.0303304. PMID: 38758919; PMCID: PMC11101101.

Turgeon AF, Fergusson DA, Clayton L, Patton MP, Neveu X, Walsh TS, Docherty A, Malbouisson LM, Pili-Floury S, English SW, Zarychanski R, Moore L, Bonaventure PL, Laroche V, Verret M, Scales DC, Adhikari NKJ, Greenbaum J, Kramer A, Rey VG, Ball I, Khwaja K, Wise M, Harvey D, Lamontagne F, Chabanne R, Algird A, Krueper S, Pottecher J, Zeiler F, Rhodes J, Rigamonti A, Burns KEA, Marshall J, Griesdale DE, Sisconetto LS, Kutsogiannis DJ, Roger C, Green R, Boyd JG, Wright J, Charbonney E, Nair P, Astles T, Sy E, Hébert PC, Chassé M, Gomez A, Ramsay T, Taljaard M, Fox-Robichaud A, Tinmouth A, St-Onge M, Costerousse O, Lauzier F; HEMOTION Trial Investigators on behalf of the Canadian Critical Care Trials Group, the Canadian Perioperative Anesthesia Clinical Trials Group, and the Canadian Traumatic Brain Injury Research Consortium. Liberal or Restrictive Transfusion Strategy in Patients with Traumatic Brain Injury. N Engl J Med. 2024 Jun 13. doi: 10.1056/NEJMoa2404360. Epub ahead of print. PMID: 38869931. New England Journal of Medicine/NEJM

Ting DK, Rosychuk RJ, Hau JP, Righolt CH, Kwong JC, Skowronski DM, Hohl CM; Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN) investigators for the Network of Canadian Emergency Researchers and the Canadian Critical Care Trials Group. Leveraging a clinical emergency department dataset to estimate two-dose COVID-19 vaccine effectiveness and duration of protection in Canada. Vaccine. 2024 Jun 14:S0264-410X(24)00699-6. doi: 10.1016/j.vaccine.2024.06.025. Epub ahead of print. PMID: 38879407.

Cook D, Taneja S, Krewulak K, Zytaruk N, Menon K, Fowler R, Lamontagne F, Kho ME, Rochwerg B, Masse MH, Lauzier F, O'Hearn K, Adhikari NKJ, Burns KEA, Bosma KJ, English S, McNally D, Turgeon AF, Brochard L, Parker M, Clayton L, Rishu A, Tuttle A, Daneman N, Fergusson D, McIntyre L, Kelly L, Orr S, Austin P, Mulligan S, Fiest K; Canadian Critical Care Trials Group and Canadian Clinical Research Network. Barriers, Solutions, and Opportunities for Adapting Critical Care Clinical Trials in the COVID-19 Pandemic. JAMA Netw Open. 2024 Jul 1;7(7):e2420458. doi: 10.1001/jamanetworkopen.2024.20458. PMID: 38995645; PMCID: PMC11245722.

Andersen CR, Presseau J, Shea B, Marti ML, McCoy M, Fernie G, McIntyre L, Delaney A, Chassé M, Saigle V, Marshall S, Fergusson DA, Graham I, Brehaut J, Turgeon AF, Lauzier F, Tugwell P, Zha X, Talbot P, Muscedere J, Marshall JC, Thavorn K, Griesdale D; Canadian Critical Care Trials Group; English SW. What to Measure in Aneurysmal Subarachnoid Haemorrhage Research-An International Delphi Survey. Transl Stroke Res. 2024 Jul 13. doi: 10.1007/s12975-024-01271-8. Epub ahead of print. PMID: 38997598.

Ganesan SL, Garros D, Foster J, Di Genova T, Fontela PS, Murthy S, for the Canadian Pediatric Intensive Care Consortium (CanPICC) of the Canadian Critical Care Trials Group (CCCTG)., Pediatric critical care capacity in Canada, Paediatrics & Child Health, 2024;, pxae024, https://doi.org/10.1093/pch/pxae024

Lin K, Xu K, Daoust R, Taylor J, Rosychuk RJ, Hau JP, Davis P, Clark G, McRae AD, Hohl CM; Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN) investigators for the Network of Canadian Emergency Researchers, the Canadian Critical Care Trials Group. Prognostic association between d-dimer thresholds and 30-day pulmonary embolism diagnosis among emergency department patients with suspected SARS-CoV-2 infection: a Canadian COVID-19 Emergency Department Rapid Response Network study. CJEM. 2023 Jan 10. doi: 10.1007/s43678-022-00440-8. Epub ahead of print. PMID: 36624252.

McIntyre LA, Fergusson DA, McArdle T, Fox-Robichaud A, English SW, Martin C, Marshall J, Cook DJ, Graham ID, Hawken S, McCartney C, Menon K, Saginur R, Seely A, Stiell I, Thavorn K, Weijer C, Iyengar A, Muscedere J, Forster AJ, Taljaard M; Canadian Critical Care Trials Group. FLUID trial: a hospital-wide open-label cluster cross-over pragmatic comparative effectiveness randomised pilot trial comparing normal saline to Ringer's lactate. BMJ Open. 2023 Feb 3;13(2):e067142. doi: 10.1136/bmjopen-2022-067142. PMID: 36737087; PMCID: PMC9900065.

Bosma KJ, Martin CM, Burns KEA, Mancebo Cortes J, Suárez Montero JC, Skrobik Y, Thorpe KE, Amaral ACK, Arabi Y, Basmaji J, Beduneau G, Beloncle F, Carteaux G, Charbonney E, Demoule A, Dres M, Fanelli V, Geagea A, Goligher E, Lellouche F, Maraffi T, Mercat A, Rodriguez PO, Shahin J, Sibley S, Spadaro S, Vaporidi K, Wilcox ME, Brochard L; Canadian Critical Care Trials Group and; REVA Network. Study protocol for a randomized controlled trial of Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation: the PROMIZING study. Trials. 2023 Mar 27;24(1):232. doi: 10.1186/s13063-023-07163-w. PMID: 36973743

Johnstone J, Muscedere J, Dionne J, Duan E, Rochwerg B, Centofanti J, Oczkowski S, Lauzier F, Marshall J, Heels-Ansdell D, Daneman N, Mehta S, Arabi Y, Zytaruk N, Dodek P, Adhikari NK, Karachi T, Charbonney E, Stelfox HT, Kristof AS, Ball I, Hand L, Fowler R, Zarychanski R, Arnaud CS, Takaoka A, Kutsogiannis J, Khwaja K, Sligl W, Loubani O, Tsang J, Lamarche D, Bowdish D, Surette M, Cook D; Prevention of Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT) Investigators and the Canadian Critical Care Trials Group. Definitions, rates and associated mortality of ICU-acquired pneumonia: A multicenter cohort study. J Crit Care. 2023 Mar 2:154284. doi: 10.1016/j.jcrc.2023.154284. Epub ahead of print. PMID: 36870801

Hohl CM, Hau JP, Vaillancourt S, Grant J, Brooks SC, Morrison LJ, Perry JJ, Rosychuk RJ; CCEDRRN investigators for the Network of Canadian Emergency Researchers and the Canadian Critical Care Trials Group. Sensitivity and Diagnostic Yield of the First SARS-CoV-2 Nucleic Acid Amplification Test Performed for Patients Presenting to the Hospital. JAMA Netw Open. 2022 Oct 3;5(10):e2236288. doi: 10.1001/jamanetworkopen.2022.36288. PMID: 36223119; PMCID: PMC9557877

Li Y, Fiest K, Burns KEA, O'Hearn K, Maratta C, Menon K, Rochwerg B, Murthy S, Fowler R, Mehta S; Canadian Critical Care Trials Group. Addressing health care inequities in Canadian critical care through inclusive science: a pilot tool for standardized data collection. Can J Anaesth. 2023 May 10. English. doi: 10.1007/s12630-023-02450-1. Epub ahead of print. PMID: 37165123.

Sarti AJ, Sutherland S, Meade M, Hornby L, Wilson LC, Landriault A, Vanderspank-Wright B, Valiani S, Keenan S, Weiss MJ, Werestiuk K, Beed S, Kramer AH, Kawchuk J, Cardinal P, Dhanani S, Lotherington K, Pagliarello G, Chassé M, Gatien M, Parsons K, Chandler JA, Nickerson P, Shemie SD; Canadian Critical Care Trials Group (CCCTG). Death determination by neurologic criteria-what do families understand? Can J Anaesth. 2023 Apr;70(4):637-650. doi: 10.1007/s12630-023-02416-3. Epub 2023 May 2. Erratum in: Can J Anaesth. 2023 May 30;: PMID: 37131029; PMCID: PMC10203015.

Full article: https://pubmed.ncbi.nlm.nih.gov/37131029/

Correction: https://pubmed.ncbi.nlm.nih.gov/37253861/

Martin SM, Tucci M, Spinella PC, Ducruet T, Fergusson DA, Freed DH,
Lacroix J, Poirier N, Ben Sivarajan V, Steiner ME, Willems A, Guerra GG, on behalf of the ABC-PICU
Investigators, the Canadian Critical Care Trials Group, the Pediatric Acute Lung Injury and Sepsis
Investigators (PALISI) Network, the BloodNet Pediatric Critical Care Blood Research Network, and the
Groupe Francophone de Réanimation et Urgences Pédiatriques, Effect of red blood cell storage time in
pediatric cardiac surgical patients: a subgroup analysis of a randomized controlled trial, JTCVS Open
(2023), doi: https://doi.org/10.1016/j.xjon.2023.04.022.

Burns KEA, Heels-Ansdell D, Thabane L, Kahn SR, Lauzier F, Mehta S, Ostermann M, Bhuptani P, Crowther MA, Finfer S, Cook DJ; PROTECT Investigators, the Canadian Critical Care Trials Group, and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Sex differences in thromboprophylaxis of the critically ill: a secondary analysis of a randomized trial. Can J Anaesth. 2023 Jun 13. English. doi: 10.1007/s12630-023-02457-8. Epub ahead of print. PMID: 37310606.