Publications

Lin K, Xu K, Daoust R, Taylor J, Rosychuk RJ, Hau JP, Davis P, Clark G, McRae AD, Hohl CM; Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN) investigators for the Network of Canadian Emergency Researchers, the Canadian Critical Care Trials Group. Prognostic association between d-dimer thresholds and 30-day pulmonary embolism diagnosis among emergency department patients with suspected SARS-CoV-2 infection: a Canadian COVID-19 Emergency Department Rapid Response Network study. CJEM. 2023 Jan 10. doi: 10.1007/s43678-022-00440-8. Epub ahead of print. PMID: 36624252.

McIntyre LA, Fergusson DA, McArdle T, Fox-Robichaud A, English SW, Martin C, Marshall J, Cook DJ, Graham ID, Hawken S, McCartney C, Menon K, Saginur R, Seely A, Stiell I, Thavorn K, Weijer C, Iyengar A, Muscedere J, Forster AJ, Taljaard M; Canadian Critical Care Trials Group. FLUID trial: a hospital-wide open-label cluster cross-over pragmatic comparative effectiveness randomised pilot trial comparing normal saline to Ringer's lactate. BMJ Open. 2023 Feb 3;13(2):e067142. doi: 10.1136/bmjopen-2022-067142. PMID: 36737087; PMCID: PMC9900065.

Fontela PS, Gaudreault J, Dagenais M, Noël KC, Déragon A, Lacroix J, Razack S, Rennick J, Quach C, McNally JD, Carnevale FA; Canadian Critical Care Trials Group. Clinical Reasoning Behind Antibiotic Use in PICUs: A Qualitative Study. Pediatr Crit Care Med. 2022 Jan 11. doi: 10.1097/PCC.0000000000002886 

Ali K, Azher T, Baqi M, Binnie A, Borgia S, Carrier FM, Cavayas YA, Chagnon N, Cheng MP, Conly J, Costiniuk C, Daley P, Daneman N, Douglas J, Downey C, Duan E, Duceppe E, Durand M, English S, Farjou G, Fera E, Fontela P, Fowler R, Fralick M, Geagea A, Grant J, Harrison LB, Havey T, Hoang H, Kelly LE, Keynan Y, Khwaja K, Klein G, Klein M, Kolan C, Kronfli N, Lamontagne F, Lau R, Fralick M, Lee TC, Lee N, Lim R, Longo S, Lostun A, MacIntyre E, Malhamé I, Mangof K, McGuinty M, Mergler S, Munan MP, Murthy S, O'Neil C, Ovakim D, Papenburg J, Parhar K, Parvathy SN, Patel C, Perez-Patrigeon S, Pinto R, Rajakumaran S, Rishu A, Roba-Oshin M, Rushton M, Saleem M, Salvadori M, Scherr K, Schwartz K, Semret M, Silverman M, Singh A, Sligl W, Smith S, Somayaji R, Tan DHS, Tobin S, Todd M, Tran TV, Tremblay A, Tsang J, Turgeon A, Vakil E, Weatherald J, Yansouni C, Zarychanski R; Canadian Treatments for COVID-19 (CATCO); Association of Medical Microbiology and Infectious Disease Canada (AMMI) Clinical Research Network and the Canadian Critical Care Trials Group.  CMAJ. 2022 Jan 19:cmaj.211698. doi: 10.1503/cmaj.211698.

Mehta S, Ahluwalia N, Heybati K, Burns KEA, Owais S, Cook DJ, Canadian Critical Care Trials Group. Diversity of Authors of Publications From the Canadian Critical Care Trials Group. Crit Care Med. 2022 Apr 1;50(4):535-542PMID: 34473658

Mehta S, Yarnell C, Shah S, Dodek P, Parsons-Leigh J, Maunder R, Kayitesi J, Eta-Ndu C, Priestap F, LeBlanc D, Chen J, Honarmand K; Canadian Critical Care Trials Group. The impact of the COVID-19 pandemic on intensive care unit workers: a nationwide survey.Can J Anaesth. 2021 Dec 23:1-13. PMID: 34940952

Fiest KM, Krewulak KD, Hernández LC, Jaworska N, Makuk K, Schalm E, Bagshaw SM, Bernet X, Burns KEA, Couillard P, Doig CJ, Fowler R, Kho ME, Kupsch S, Lauzier F, Niven DJ, Oggy T, Rewa OG, Rochwerg B, Spence S, West A, Stelfox HT, Parsons Leigh J, Canadian Critical Care Trials Group. Evidence-informed consensus statements to guide COVID-19 patient visitation policies: results from a national stakeholder meeting. Can J Anaesth 2022; Jul;69(7):868-879. PMID: 35359262 Read the full article

Takaoka A, Zytaruk N, Davis M, Matte A, Johnstone J, Lauzier F, Marshall J, Adhikari N, Clarke FJ, Rochwerg B, Lamontagne F,  Hand L, Watpool I, Porteous RK, Masse M, D'Aragon F, Niven D, Heels-Ansdell D, Duan E, Dionne J, English S, St-Arnaud C, Millen T, Cook DJ, PROSPECT Investigators and the Canadian Critical Care Trials Group. Monitoring and auditing protocol adherence, data integrity and ethical conduct of a randomized clinical trial: A case study. J Crit Care 2022 Jun 17;71:154094. PMID: 35724443

Hohl CM, Rosychuk RJ, Hau JP, Hayward  J, Landes M, Yan JW, Ting DK, Welsford M, Archambault PM, Mercier E, Chandra K, Davis P, Vaillancourt S, Leeies M, Small S, Morrison LJ, Canadian COVID-19 Rapid Response Network (CCEDRRN) investigators for the Network of Canadian Emergency Researchers, for the Canadian Critical Care Trials Group. Treatments, resource utilization, and outcomes of COVID-19 patients presenting to emergency departments across pandemic waves: an observational study by the Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN). CJEM 2022 Jun;24(4):397-407. PMID: 35362857

Foster JR, Lee LA, Seabrook JA, Ryan M Betts LJ, Burgess SA, Slumkoski C, Walls M, Garros D, and Canadian Critical Care Trials Group. Family presence in Canadian PICUs during the COVID-19 pandemic: a mixed-methods environmental scan of policy and practice. CMAJ Jul-Sep 2022. PMID: 35790228

F. Lamontagne, M.-H. Masse, J. Menard, S. Sprague, R. Pinto, D.K. Heyland, D.J Cook, M.-C. Battista, A.G. Day, G.H. Guyatt, S. Kanji, R. Parke, S.P. McGuinness, B.-K. Tirupakuzhi Vijayaraghavan, D. Annane, D. Cohen, Y.M. Arabi, B. Bolduc, N. Marinoff, B. Rochwerg, T. Millen, M.O. Meade, L. Hand, I. Watpool, R. Porteous, P.J. Young, F. D’Aragon, E.P. Belley-Cote, E. Carbonneau, F. Clarke, D.M. Maslove, M. Hunt, M. Chassé, M. Lebrasseur, F. Lauzier, S. Mehta, H. Quiroz-Martinez, O.G. Rewa, E. Charbonney, A.J.E. Seely, D.J. Kutsogiannis, R. LeBlanc, A. Mekontso-Dessap, T.S. Mele, A.F. Turgeon, G. Wood, S.S. Kohli, J. Shahin, P. Twardowski, and N.K.J. Adhikari, for the LOVIT Investigators and the Canadian Critical Care Trials Group. Intravenous Vitamin C in Adults with Sepsis in the Intensive Care Unit. NEJM. June 15, 2022
DOI: 10.1056/NEJMoa2200644

Sarti AJ, Sutherland S, Meade M, Shemie S, Landriault A, Vanderspank-Wright B, Valiani S, Keenan S, Weiss MJ, Werestiuk K, Kramer AH, Kawchuk J, Beed S, Dhanani S, Pagliarello G, Chassé M, Lotherington K, Gatien M, Parsons K,  Chandler JA, Nickerson P, Cardinal P
CMAJ Aug 2022, 194 (30) E1054-E1061; DOI: 10.1503/cmaj.220508

Davis P, Rosychuk R, Hau JP, Cheng I, McRae AD, Daoust R, Lang E, Turner J, Khangura J, Fok PT, Stachura M, Brar B, Hohl CM; CCEDRRN investigators, and for the Network of Canadian Emergency Researchers and the Canadian Critical Care Trials Group.BMJ Open. 2022 Aug 10;12(8):e057852. doi: 10.1136/bmjopen-2021-057852.PMID: 35948378

Pong S, Fowler RA, Murthy S, Pernica JM, Gilfoyle E, Fontela P, Rishu AH, Mitsakakis N, Hutchison JS, Science M, Seto W, Jouvet P, Daneman N; Canadian Critical Care Trials Group. Antimicrobial treatment duration for uncomplicated bloodstream infections in critically ill children: a multicentre observational study. BMC Pediatr. 2022 Apr 5;22(1):179. PMID: 35382774

Ista E, Redivo J, Kananur P, Choong K, Colleti J Jr, Needham DM, Awojoodu R, Kudchadkar SR; International PARK-PICU Investigators. ABCDEF Bundle Practices for Critically Ill Children: An International Survey of 161 PICUs in 18 Countries. Crit Care Med. 2022 Jan 1;50(1):114-125. PMID: 34259659

ISARIC Clinical Characterization Group, Garcia-Gallo E, Merson L, Kennon K, Kelly S, Citarella BW, Fryer DV, Shrapnel S, Lee J, Duque S, Fuentes YV, Balan V, Smith S, Wei J, Gonçalves BP, Russell CD, Sigfrid L, Dagens A, Olliaro PL, Baruch J, Kartsonaki C, Dunning J, Rojek A, Rashan A, Beane A, Murthy S, Reyes LF. ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19. Sci Data. 2022 Jul 30;9(1):454. PMID: 35908040

Turgeon AF, Fergusson DA, Clayton L, Patton M-P, Zarychanski R, English S, Docherty A, Walsh T, Griesdale D, Kramer AH, Scales D, Burns KEA, Boyd JG, Marshall JC, Kutsogiannis DJ, Ball I, Hébert PC, Lamontagne F, Costerousse O, St-Onge M, Lessard Bonaventure P, Moore L, Neveu X, Rigamonti A, Khwaja K, Green RS, Laroche V, Fox-Robichaud A, Lauzier F for the HEMOTION Trial Team, the Canadian Critical Care Trials Group, the Canadian Perioperative Anesthesia Clinical Trials Group and the Canadian Traumatic Brain Injury Research Consortium. Haemoglobin transfusion threshold in traumatic brain injury optimisation (HEMOTION): a multicentre, randomised, clinical trial protocol.  BMJ Open
2022;12:e067117. doi:10.1136/bmjopen-2022-067117

Lau VI, Fowler R, Pinto R, Tremblay A, Borgia S, Carrier FM, Cheng MP, Conly J, Costiniuk CT, Daley P, Duan E, Durand M, Fontela PS, Farjou G, Fralick M, Geagea A, Grant J, Keynan Y, Khwaja K, Lee N, Lee TC, Lim R, O’Neil CR, Papenburg J, Semret M, Silverman M, Sligl W, Somayaji R, Tan DHS, Tsang JLY, Weatherald J, Yansouni CP, Zarychanski R and Murthy S for the E-CATCO authors, AMMI Clinical Research Network and Canadian Critical Care Trials Group. Cost-effectiveness of remdesivir plus usual care versus usual care alone for hospitalized patients with COVID-19: an economic evaluation as part of the Canadian Treatments for COVID-19 (CATCO) randomized clinical trial. September 06, 2022 10 (3) E807-E817; DOI: https://doi.org/10.9778/cmajo.20220077

Patient and family engagement in patient care and research in Canadian intensive care units: a national survey. Burns KEA, McDonald E, Debigaré S, Zamir N, Vasquez M, Piche-Ayotte M, Oczkowski S, Canadian Critical Care Trials Group. Can J Anesth/J Can Anesth (2022) 69:1527–1536

O'Hearn K, Cayouette F, Cameron S, Martin DA, Tsampalieros A, Menon K; Canadian Critical Care Trials Group. Assent in Pediatric Critical Care Research: A Cross-Sectional Stakeholder Survey of Canadian Research Ethics Boards, Research Coordinators, Pediatric Critical Care Researchers, and Nurses. Pediatr Crit Care Med. 2022 Oct 13. doi: 10.1097/PCC.0000000000003135. Epub ahead of print. PMID: 36511694.

Brooks SC, Rosychuk RJ, Perry JJ, Morrison LJ, Wiemer H, Fok P, Rowe BH, Daoust R, Vatanpour S, Turner J, Landes M, Ohle R, Hayward J, Scheuermeyer F, Welsford M, Hohl C; Canadian COVID‐19 Rapid Response Network (CCEDRRN) for the Network of Canadian Emergency Researchers (NCER) and the Canadian Critical Care Trials Group (CCCTG). Derivation and validation of a clinical decision rule to risk-stratify COVID-19 patients discharged from the emergency department: The CCEDRRN COVID discharge score. J Am Coll Emerg Physicians Open. 2022 Dec 22;3(6):e12868. doi: 10.1002/emp2.12868. PMID: 36579029; PMCID: PMC9780419.

Dhanani S, Hornby L, van Beinum A, Scales NB, Hogue M, Baker A, Beed S, Boyd JG, Chandler JA, Chassé M, D'Aragon F, Dezfulian C, Doig CJ, Duska F, Friedrich JO, Gardiner D, Gofton T, Harvey D, Herry C, Isac G, Kramer AH, Kutsogiannis DJ, Maslove DM, Meade M, Mehta S, Munshi L, Norton L, Pagliarello G, Ramsay T, Rusinova K, Scales D, Schmidt M, Seely A, Shahin J, Slessarev M, So D, Talbot H, van Mook WNKA, Waldauf P, Weiss M, Wind JT, Shemie SD; Canadian Critical Care Trials Group and the Canadian Donation and Transplantation Research Program.  Resumption of Cardiac Activity after Withdrawal of Life-Sustaining Measures. N Engl J Med. 2021 Jan 28;384(4):345-352. PMID: 33503343

Burns KEA, Rizvi L, Cook DJ, Lebovic G, Dodek P, Villar J, Slutsky AS, Jones A, Kapadia FN, Gattas DJ, Epstein SK, Pelosi P, Kefala K, Meade MO; Canadian Critical Care Trials Group. Ventilator Weaning and Discontinuation Practices for Critically Ill Patients.JAMA. 2021 Mar 23;325(12):1173-1184. PMID: 33755077

Kirsten M. Fiest, Karla D. Krewulak, Carmen Hiploylee, Sean M. Bagshaw, Karen E. A. Burns, Deborah J. Cook, Robert A. Fowler, Maia S. Kredentser, Daniel J. Niven, Kendiss Olafson, Ken Kuljit, S. Parhar, Scott B. Patten, Alison E. Fox-Robichaud, Oleksa G. Rewa, Bram Rochwerg, Krista L. Spence, Sharon E. Straus, Sean Spence, Andrew West, Henry T. Stelfox, Jeanna Parsons Leigh, for the Canadian Critical Care Trials Group. An environmental scan of visitation policies in Canadian intensive care units during the first wave of the COVID-19 pandemic. Can J Anesth 2021, 8 February.