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Early Rehabilitation in Critically ill Children: A Two Center Implementation Study

First Author:

Choong K

Journal:

Pediatr Crit Care Med.

Year:

2024

Group:

,

Choong K, Fraser DD, Al-Farsi A, Awlad Thani S, Cameron S, Clark H, Cuello C, Debigaré S, Ewusie J, Kennedy K, Kho ME, Krasevich K, Martin CM, Thabane L, Nanji J, Watts C, Simpson A, Todt A, Wong J, Xie F, Vu M, Cupido C; Canadian Critical Care Trials Group. Early Rehabilitation in Critically ill Children: A Two Center Implementation Study. Pediatr Crit Care Med. 2024 Feb 1;25(2):92-105. doi: 10.1097/PCC.0000000000003343. Epub 2024 Jan 19. PMID: 38240534.

Post-Intensive Care Sequelae in Pediatrics-Results of an Early Rehabilitation Implementation Study

First Author:

Choong K

Journal:

Pediatr Crit Care Med

Year:

2024

Group:

,

Choong K, Fraser DD, Cameron S, Cuello C, Debigaré S, Ewusie J, Kho ME, Krasevich K, Martin CM, Thabane L, Todt A, Cupido C; Canadian Critical Care Trials Group. Post-Intensive Care Sequelae in Pediatrics-Results of an Early Rehabilitation Implementation Study. Pediatr Crit Care Med. 2024 Feb 2. doi: 10.1097/PCC.0000000000003467. Epub ahead of print. PMID: 38305699.

Pediatric critical care capacity in Canada

First Author:

Ganesan SL

Journal:

Paediatrics & Child Health

Year:

2024

Group:

,

Ganesan SL, Garros D, Foster J, Di Genova T, Fontela PS, Murthy S, for the Canadian Pediatric Intensive Care Consortium (CanPICC) of the Canadian Critical Care Trials Group (CCCTG)., Pediatric critical care capacity in Canada, Paediatrics & Child Health, 2024;, pxae024, https://doi.org/10.1093/pch/pxae024

Statistical analysis plan for the SQUEEZE trial: A trial to determine whether septic shock reversal is quicker in pediatric patients randomized to an early goal-directed fluid-sparing strategy vs. usual care (SQUEEZE)

First Author:

Parker MJ

Journal:

Crit Care Resusc

Year:

2024

Group:

, ,

Parker MJ, Foster G, Fox-Robichaud A, Choong K, Mbuagbaw L, Thabane L; With the SQUEEZE Trial Steering Committee and on behalf of the SQUEEZE Trial Investigators, the Canadian Critical Care Trials Group, Pediatric Emergency Research Canada, and the Canadian Critical Care Translational Biology Group. Statistical analysis plan for the SQUEEZE trial: A trial to determine whether septic shock reversal is quicker in pediatric patients randomized to an early goal-directed fluid-sparing strategy vs. usual care (SQUEEZE). Crit Care Resusc. 2024 Jun 22;26(2):123-134. doi: 10.1016/j.ccrj.2024.02.002. PMID: 39072232; PMCID: PMC11282343.

Rapid normalization of vitamin D deficiency in PICU (VITdALIZE-KIDS): study protocol for a phase III, multicenter randomized controlled trial

First Author:

O'Hearn K

Journal:

Trials

Year:

2024

Group:

,

O'Hearn K, Menon K, Albrecht L, Amrein K, Britz-McKibbin P, Cayouette F, Choong K, Foster JR, Fergusson DA, Floh A, Fontela P, Geier P, Gilfoyle E, Guerra GG, Gunz A, Helmeczi E, Khamessan A, Joffe AR, Lee L, McIntyre L, Murthy S, Parsons SJ, Ramsay T, Ryerson L, Tucci M, McNally D; Canadian Critical Care Trials Group. Rapid normalization of vitamin D deficiency in PICU (VITdALIZE-KIDS): study protocol for a phase III, multicenter randomized controlled trial. Trials. 2024 Sep 19;25(1):619. doi: 10.1186/s13063-024-08461-7. PMID: 39300483.

Family member experience with restricted family presence in Canadian PICUs: an interpretive descriptive study

First Author:

Foster JR

Journal:

Eur J Pediatr

Year:

2024

Group:

,

Foster JR, Ryan MJ, Garros D, Walls M, Slumkoski C, Moghadam N, Ajidahun A, Seabrook JA, Lee LA; RFP-PICU research group for the Canadian Critical Care Trials Group. Family member experience with restricted family presence in Canadian PICUs: an interpretive descriptive study. Eur J Pediatr. 2024 Nov 29;184(1):52. doi: 10.1007/s00431-024-05854-3. PMID: 39609280; PMCID: PMC11604798.

Remdesivir for the treatment of patients in hospital with COVID-19 in Canada: a randomized controlled trial

First Author:

Ali K

Journal:

CMAJ

Year:

2022

Group:

,

Ali K, Azher T, Baqi M, Binnie A, Borgia S, Carrier FM, Cavayas YA, Chagnon N, Cheng MP, Conly J, Costiniuk C, Daley P, Daneman N, Douglas J, Downey C, Duan E, Duceppe E, Durand M, English S, Farjou G, Fera E, Fontela P, Fowler R, Fralick M, Geagea A, Grant J, Harrison LB, Havey T, Hoang H, Kelly LE, Keynan Y, Khwaja K, Klein G, Klein M, Kolan C, Kronfli N, Lamontagne F, Lau R, Fralick M, Lee TC, Lee N, Lim R, Longo S, Lostun A, MacIntyre E, Malhamé I, Mangof K, McGuinty M, Mergler S, Munan MP, Murthy S, O'Neil C, Ovakim D, Papenburg J, Parhar K, Parvathy SN, Patel C, Perez-Patrigeon S, Pinto R, Rajakumaran S, Rishu A, Roba-Oshin M, Rushton M, Saleem M, Salvadori M, Scherr K, Schwartz K, Semret M, Silverman M, Singh A, Sligl W, Smith S, Somayaji R, Tan DHS, Tobin S, Todd M, Tran TV, Tremblay A, Tsang J, Turgeon A, Vakil E, Weatherald J, Yansouni C, Zarychanski R; Canadian Treatments for COVID-19 (CATCO); Association of Medical Microbiology and Infectious Disease Canada (AMMI) Clinical Research Network and the Canadian Critical Care Trials Group.  CMAJ. 2022 Jan 19:cmaj.211698. doi: 10.1503/cmaj.211698.

Family presence in Canadian PICUs during the COVID-19 pandemic: a mixed-methods environmental scan of policy and practice

First Author:

Foster JR

Journal:

CMAJ

Year:

2022

Group:

,

Foster JR, Lee LA, Seabrook JA, Ryan M Betts LJ, Burgess SA, Slumkoski C, Walls M, Garros D, and Canadian Critical Care Trials Group. Family presence in Canadian PICUs during the COVID-19 pandemic: a mixed-methods environmental scan of policy and practice. CMAJ Jul-Sep 2022. PMID: 35790228

The experiences of family members of deceased organ donors and suggestions to improve the donation process: a qualitative study

First Author:

Sarti AJ

Journal:

CMAJ

Year:

2022

Group:

,

Sarti AJ, Sutherland S, Meade M, Shemie S, Landriault A, Vanderspank-Wright B, Valiani S, Keenan S, Weiss MJ, Werestiuk K, Kramer AH, Kawchuk J, Beed S, Dhanani S, Pagliarello G, Chassé M, Lotherington K, Gatien M, Parsons K,  Chandler JA, Nickerson P, Cardinal P
CMAJ Aug 2022, 194 (30) E1054-E1061; DOI: 10.1503/cmaj.220508

Antimicrobial treatment duration for uncomplicated bloodstream infections in critically ill children: a multicentre observational study

First Author:

Pong S

Journal:

BMC Pediatr

Year:

2022

Group:

,

Pong S, Fowler RA, Murthy S, Pernica JM, Gilfoyle E, Fontela P, Rishu AH, Mitsakakis N, Hutchison JS, Science M, Seto W, Jouvet P, Daneman N; Canadian Critical Care Trials Group. Antimicrobial treatment duration for uncomplicated bloodstream infections in critically ill children: a multicentre observational study. BMC Pediatr. 2022 Apr 5;22(1):179. PMID: 35382774

ABCDEF Bundle Practices for Critically Ill Children: An International Survey of 161 PICUs in 18 Countries

First Author:

Ista E

Journal:

Crit Care Med

Year:

2022

Group:

,

Ista E, Redivo J, Kananur P, Choong K, Colleti J Jr, Needham DM, Awojoodu R, Kudchadkar SR; International PARK-PICU Investigators. ABCDEF Bundle Practices for Critically Ill Children: An International Survey of 161 PICUs in 18 Countries. Crit Care Med. 2022 Jan 1;50(1):114-125. PMID: 34259659

ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

First Author:

ISARIC Clinical Characterization Group

Journal:

Sci Data

Year:

2022

Group:

,

ISARIC Clinical Characterization Group, Garcia-Gallo E, Merson L, Kennon K, Kelly S, Citarella BW, Fryer DV, Shrapnel S, Lee J, Duque S, Fuentes YV, Balan V, Smith S, Wei J, Gonçalves BP, Russell CD, Sigfrid L, Dagens A, Olliaro PL, Baruch J, Kartsonaki C, Dunning J, Rojek A, Rashan A, Beane A, Murthy S, Reyes LF. ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19. Sci Data. 2022 Jul 30;9(1):454. PMID: 35908040

Assent in Pediatric Critical Care Research: A Cross-Sectional Stakeholder Survey of Canadian Research Ethics Boards, Research Coordinators, Pediatric Critical Care Researchers, and Nurses

First Author:

O'Hearn K

Journal:

Pediatr Crit Care Med

Year:

2022

Group:

,

O'Hearn K, Cayouette F, Cameron S, Martin DA, Tsampalieros A, Menon K; Canadian Critical Care Trials Group. Assent in Pediatric Critical Care Research: A Cross-Sectional Stakeholder Survey of Canadian Research Ethics Boards, Research Coordinators, Pediatric Critical Care Researchers, and Nurses. Pediatr Crit Care Med. 2022 Oct 13. doi: 10.1097/PCC.0000000000003135. Epub ahead of print. PMID: 36511694.

Resumption of Cardiac Activity after Withdrawal of Life-Sustaining Measures

First Author:

Dhanani S

Journal:

N Engl J Med

Year:

2021

Group:

,

Dhanani S, Hornby L, van Beinum A, Scales NB, Hogue M, Baker A, Beed S, Boyd JG, Chandler JA, Chassé M, D'Aragon F, Dezfulian C, Doig CJ, Duska F, Friedrich JO, Gardiner D, Gofton T, Harvey D, Herry C, Isac G, Kramer AH, Kutsogiannis DJ, Maslove DM, Meade M, Mehta S, Munshi L, Norton L, Pagliarello G, Ramsay T, Rusinova K, Scales D, Schmidt M, Seely A, Shahin J, Slessarev M, So D, Talbot H, van Mook WNKA, Waldauf P, Weiss M, Wind JT, Shemie SD; Canadian Critical Care Trials Group and the Canadian Donation and Transplantation Research Program.  Resumption of Cardiac Activity after Withdrawal of Life-Sustaining Measures. N Engl J Med. 2021 Jan 28;384(4):345-352. PMID: 33503343 

Characteristics and outcomes of patients with COVID-19 admitted to hospital and intensive care in the first phase of the pandemic in Canada: a national cohort study

First Author:

Murthy, S

Journal:

CMAJ

Year:

2021

Group:

,

S Murthy, PM Archambault, A Atique, FM Carrier, MP Cheng, C Codan, N Daneman, W Dechert, S Douglas, KM Fiest, R Fowler, G Goco, Y Gu, A Guerguerian, R Hall, JM Hsu, A Joffe, P Jouvet, L Kelly, ME Kho, RJ Kruisselbrink, D Kumar, DJ Kutsogiannis, F Lamontagne, TC Lee, KMenon, H O'Grady, K O'Hearn, DH Ovakim, SG Pharand, T Pitre, R Reel, B Reeve, O Rewa, D Richardson, A Rishu, G Sandhu, S Sarfo-Mensah, E Shadowitz, W Sligl, J Solomon, HT Stelfox, A Swanson, H Tessier-Grenier, JLY Tsang, G Wood, SPRINT-SARI Canada Investigators and the Canadian Critical Care Trials Group. Characteristics and outcomes of patients with COVID-19 admitted to hospital and intensive care in the first phase of the pandemic in Canada: a national cohort study. CMAJ 2021 Mar 8;9(1):E181-E188. PMID: 33688026

Consent models in Canadian critical care randomized controlled trials: a scoping review

First Author:

O'Hearn, K

Journal:

Can J Anaesth

Year:

2021

Group:

, ,

O'Hearn K, Gibson J, Krewulak K, Porteous R, Saigle V, Sampson M, Tsampalieros A, Barrowman N, Cameron S; Canadian Critical Care Trials Group. Consent models in Canadian critical care randomized controlled trials: a scoping review. Can J Anaesth. 2022 Apr;69(4):513-526. English. doi: 10.1007/s12630-021-02176-y. Epub 2021 Dec 14. PMID: 34907503.

Clinical evaluation and ancillary testing for the diagnosis of death by neurologic criteria: a cross-sectional survey of Canadian intensivists

First Author:

Chassé M

Journal:

Can J Anaesth

Year:

2021

Group:

,

Chassé M, Neves Briard J, Yu M, P Carvalho L, W English S, D'Aragon F, Lauzier F, F Turgeon A, Dhanani S, McIntyre L, D Shemie S, Knoll G, Fergusson DA, Anthony SJ, Weiss MJ; Canadian Critical Care Trials Group. Clinical evaluation and ancillary testing for the diagnosis of death by neurologic criteria: a cross-sectional survey of Canadian intensivists. Can J Anaesth. 2022 Mar;69(3):353-363. English. doi: 10.1007/s12630-021-02166-0. Epub 2021 Dec 20. PMID: 34931292.

Music Use for Sedation in Critically ill Children (MUSiCC trial): a pilot randomized controlled trial

First Author:

Garcia Guerra G

Journal:

J Intensive Care

Year:

2021

Group:

,

Garcia Guerra G, Joffe AR, Sheppard C, Hewson K, Dinu IA, Hajihosseini M, deCaen A, Jou H, Hartling L, Vohra S; Canadian Critical Care Trials Group. Music Use for Sedation in Critically ill Children (MUSiCC trial): a pilot randomized controlled trial. J Intensive Care. 2021 Jan 12;9(1):7. doi: 10.1186/s40560-020-00523-7. PMID: 33431051; PMCID: PMC7802123.

Moral Distress and Other Wellness Measures in Canadian Critical Care Physicians

First Author:

Dodek PM

Journal:

Ann Am Thorac Soc

Year:

2021

Group:

,

Dodek PM, Cheung EO, Burns KEA, Martin CM, Archambault PM, Lauzier F, Sarti AJ, Mehta S, Fox-Robichaud AE, Seely AJE, Parshuram C, Garros D, Withington DE, Cook DJ, Piquette D, Carnevale FA, Boyd JG, Downar J, Kutsogiannis DJ, Chassé M, Fontela P, Fowler RA, Bagshaw S, Dhanani S, Murthy S, Gehrke P, Fujii T. Moral Distress and Other Wellness Measures in Canadian Critical Care Physicians. Ann Am Thorac Soc. 2021 Aug;18(8):1343-1351. PMID: 33356972

Music Use for Sedation in Critically ill Children (MUSiCC trial): study protocol for a pilot randomized controlled trial

First Author:

Garcia Guerra G

Journal:

Pilot Feasibility Stud.

Year:

2020

Group:

,

Garcia Guerra G, Joffe A, Sheppard C, Hewson K, Dinu IA, de Caen A, Jou H, Hartling L, Vohra S; Canadian Critical Care Trials Group. Music Use for Sedation in Critically ill Children (MUSiCC trial): study protocol for a pilot randomized controlled trial. Pilot Feasibility Stud. 2020 Feb 25;6:31. doi: 10.1186/s40814-020-0563-x. eCollection 2020.. PMID: 32128249

Data initiatives supporting critical care research and quality improvement in Canada: an environmental scan and narrative review

First Author:

Chornenki JN

Journal:

Can J Anaesth.

Year:

2020

Chornenki JN, Liaw P, Bagshaw S, Burns K, Dodek P, English S, Fan E, Ferrari N, Fowler R, Fox-Robichaud A, Garland A, Green R, Hebert P, Kho M, Martin C, Maslove D, McDonald E, Menon K, Murthy S, Muscedere J, Scales D, Stelfox HT, Wang HT, Weiss M; Canadian Critical Care Trials Group (CCCTG) and Canadian Critical Care Translational Biology Group (CCCTBG). Data initiatives supporting critical care research and quality improvement in Canada: an environmental scan and narrative review. Can J Anaesth. 2020 Apr;67(4):475-484.

Survey of Canadian critical care physicians' knowledge and attitudes towards legislative aspects of the deceased organ donation system

First Author:

Weiss MJ

Journal:

Can J Anaesth.

Year:

2020

Group:

,

Weiss MJ, English SW, D'Aragon F, Lauzier F, Turgeon AF, Dhanani S, McIntyre L, Carvalho LP, Yu M, Shemie SD, Knoll G, Fergusson DA, Anthony SJ, Haj-Moustafa A, Hartell D, Mohr J, Chassé M; Canadian Critical Care Trials Group.Survey of Canadian critical care physicians' knowledge and attitudes towards legislative aspects of the deceased organ donation system. Can J Anaesth. 2020 Oct;67(10):1349-1358.

International Survey on Determinants of Antibiotic Duration and Discontinuation in Pediatric Critically Ill Patients

First Author:

Noel KC

Journal:

Pediatr. Crit Care Med

Year:

2020

Group:

,

KC Noël, J Papenburg, J Lacroix, C Quach, S O'Donnell, M Gonzales, DF Willson, E Gilfoyle, JD McNally, S Reynolds, Y Kazzaz, A Kawaguchi, M Sato, L Kongkiattikul, S Leteurtre, F Dubos, Y Karaca, F Chiusolo, J Piva, N Dendukuri, PS Fontela, Canadian Critical Care Trials Group (CCCTG) and the Pediatric Lung Injury and Sepsis Investigators (PALISI) Network. International Survey on Determinants of Antibiotic Duration and Discontinuation in Pediatric Critically Ill Patients. Pediatr. Crit Care Med. 2020; Sep;21(9):e696-e706 PMID: 32639469

Survey of Canadian intensivists on physician non-referral and family override of deceased organ donation.

First Author:

Weiss MJ

Journal:

Can J Anaesth.

Year:

2020

Group:

,

Weiss MJ, English SW, D'Aragon F, Lauzier F, Turgeon AF, Dhanani S, McIntyre L, Shemie SD, Knoll G, Fergusson DA, Anthony SJ, Haj-Moustafa A, Hartell D, Mohr J, Chassé M; Canadian Critical Care Trials Group. Survey of Canadian intensivists on physician non-referral and family override of deceased organ donation. Can J Anaesth. 2019, 67(3):313-323. PMID: 31768789