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Age of Transfused Blood in Critically Ill Adults

First Author:

Lacroix J

Journal:

N Engl J Med

Year:

2015

Group:

, ,

Lacroix, J, Hébert, PC, Fergusson, DA, Tinmouth, A, Cook, DJ, Marshall, JC, Clayton, L, McIntyre, L, Callum, J, Turgeon, AF, Blajchman, MA, Walsh, TS, Stanworth, SJ, Campbell, H, Capellier, G, Tiberghien, P, Bardiaux, L, van de Watering, L, van der Meer, NJ, Sabri, E, Vo, D for the ABLE Investigators and the Canadian Critical Care Trials Group. Age of Transfused Blood in Critically Ill Adults.N Engl J Med. 2015, 372(15):1410-8. PMID: 25776801

Patient safety, resident well-being and continuity of care with different resident duty schedules in the intensive care unit: a randomized trial.

First Author:

Parshuram CS

Journal:

CMAJ

Year:

2015

Group:

,

Parshuram CS, Amaral AC, Ferguson ND, Baker GR, Etchells EE, Flintoft V, Granton J, Lingard L, Kirpalani H, Mehta S, Moldofsky H, Scales DC, Stewart TE, Willan AR, Friedrich JO; Canadian Critical Care Trials Group. Patient safety, resident well-being and continuity of care with different resident duty schedules in the intensive care unit: a randomized trial. CMAJ. 2015 Mar 17;187(5):321-9. PMID: 25667258

Indications and Effects of Plasma Transfusions in Critically Ill Children.

First Author:

Karam O

Journal:

Am J Respir Crit Care Med

Year:

2015

Group:

,

Karam O, Demaret P, Shefler A, Leteurtre S, Spinella P, Stanworth S, Tucci M; Canadian Critical Care Trials Group (CCCTG), Pediatric Acute Lung Injury and Sepsis Investigators (PALISI), BloodNet, and the PlasmaTV investigators. Indications and Effects of Plasma Transfusions in Critically Ill Children. Am J Respir Crit Care Med. 2015 Jun 15;191(12):1395-402. PMID: 25859890

Critical Care capacity in Canada: results of a national cross-sectional study.

First Author:

Fowler RA

Journal:

Crit Care

Year:

2015

Group:

, ,

Fowler RA, Abdelmalik P, Wood G, Foster D, Gibney N, Bandrauk N, Turgeon AF, Lamontagne F, Kumar A, Zarychanski R, Green R, Bagshaw SM, Stelfox HT, Foster R, Dodek P, Shaw S, Granton J, Lawless B, Hill A, Rose L, Adhikari NK, Scales DC, Cook DJ, Marshall JC, Martin C, Jouvet P; Canadian Critical Care Trials Group and The Canadian ICU Capacity Group. Critical Care capacity in Canada: results of a national cross-sectional study. Crit Care. 2015 Apr 1;19(1):133. PMID: 25888116

Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE): study protocol for a pilot randomized controlled trial.

First Author:

Daneman N

Journal:

Trials

Year:

2015

Group:

,

Daneman N, Rishu AH, Xiong W, Bagshaw SM, Cook DJ, Dodek P, Hall R, Kumar A, Lamontagne F, Lauzier F, Marshall JC, Martin CM, McIntyre L, Muscedere J, Reynolds S, Stelfox HT, Fowler RA; Canadian Critical Care Trials Group. Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE): study protocol for a pilot randomized controlled trial. Trials. 2015 Apr 18;16(1):173. PMID: 25903783

Exploration of Withdrawal of Life-Sustaining Therapy in Canadian Intensive Care Units.

First Author:

van Beinum A

Journal:

J Intensive Care Med

Year:

2015

Group:

van Beinum A, Hornby L, Ramsay T, Ward R, Shemie SD, Dhanani S. Exploration of Withdrawal of Life-Sustaining Therapy in Canadian Intensive Care Units. J Intensive Care Med. 2015 Feb 12. [Epub ahead of print] PMID: 25680980

Predicting time to death after withdrawal of life-sustaining therapy.

First Author:

Munshi L

Journal:

Intensive Care Med

Year:

2015

Group:

Munshi L, Dhanani S, Shemie SD, Hornby L, Gore G, Shahin J. Predicting time to death after withdrawal of life-sustaining therapy. Intensive Care Med. 2015 Jun;41(6):1014-28. PMID: 25944573

The Very Elderly Admitted to ICU: A Quality Finish?

First Author:

Heyland DK

Journal:

Crit Care Med

Year:

2015

Group:

Heyland DK, Cook D, Bagshaw SM, Garland A, Stelfox HT, Mehta S, Dodek P, Kutsogiannis J, Burns K, Muscedere J, Turgeon AF, Fowler R, Jiang X, Day AG; Canadian Critical Care Trials Group and the Canadian Researchers at the End of Life Network. The Very Elderly Admitted to ICU: A Quality Finish? Crit Care Med. 2015Jul;43(7):1352-60. PMID: 25901550

Evaluating processes of care and outcomes of children in hospital (EPOCH): study protocol for a randomized controlled trial.

First Author:

Parshuram CS

Journal:

Trials

Year:

2015

Group:

,

Parshuram CS, Dryden-Palmer K, Farrell C, Gottesman R, Gray M, Hutchison JS, Helfaer M, Hunt E, Joffe A, Lacroix J, Nadkarni V, Parkin P, Wensley D, Willan AR; Canadian Critical Care Trials Group .Evaluating processes of care and outcomes of children in hospital (EPOCH): study protocol for a randomized controlled trial. Trials. 2015;16(1):245. PMID: 26033094

Intensive versus conventional glucose control in critically ill patients with traumatic brain injury: long-term follow-up of a subgroup of patients from the NICE-SUGAR study

First Author:

NICE-SUGAR Study Investigators

Journal:

Intensive Care Med

Year:

2015

Group:

,

NICE-SUGAR Study Investigators for the Australian and New Zealand Intensive Care Society Clinical Trials Group and the Canadian Critical Care Trials Group. Intensive versus conventional glucose control in critically ill patients with traumatic brain injury: long-term follow-up of a subgroup of patients from the NICE-SUGAR study. Intensive Care Med. 2015 Jun;41(6):1037-47. PMID: 26088909

Postintubation hypotension in intensive care unit patients: A multicenter cohort study.

First Author:

Green RS

Journal:

J Crit Care

Year:

2015

Group:

Green RS, Turgeon AF, McIntyre LA, Fox-Robichaud AE, Fergusson DA, Doucette S, Butler MB, Erdogan M; Canadian Critical Care Trials Group (CCCTG). Postintubation hypotension in intensive care unit patients: A multicenter cohort study. J Crit Care. 2015 Oct;30(5):1055-60. PMID: 26117220

Comparison of standard and accelerated initiation of renal replacement therapy in acute kidney injury

First Author:

Wald R

Journal:

Kidney Int

Year:

2015

Group:

Wald, R, Adhikari, NKJ, Smith, OM, Weir, MA, Pope, K, Cohen, A, Thorpe, K, McIntyre, L, Lamontagne, F, Soth, M, Herridge, M, Lapinsky, S, Clark, E, Garg, AX, Hiremath, S, Klein, D, Mazer, CD, Richardson, RMA, Wilcox, EM, Friedrich, JO, Burns, KEA and Bagshaw, SM on behalf of the Canadian Critical Care Trials Group. Comparison of standard and accelerated initiation of renal replacement therapy in acute kidney injury. Kidney Int. 2015 Oct;88(4):897-904. PMID: 26154928

The ABLE study: A randomized controlled trial on the efficacy of fresh red cell units to improve the outcome of transfused critically ill adult

First Author:

Lacroix J

Journal:

Transfus Clin Biol

Year:

2015

Group:

,

Lacroix J, Hébert PC, Fergusson D, Tinmouth A, Capellier G, Tiberghien P, Bardiaux L; Canadian Critical Care Trials Group. The ABLE study: A randomized controlled trial on the efficacy of fresh red cell units to improve the outcome of transfused critically ill adults. Transfus Clin Biol. 2015 Aug;22(3):107-11. French. PMID: 26049675

Recall of ICU Stay in Patients Managed With a Sedation Protocol or a Sedation Protocol With Daily Interruption.

First Author:

Burry L

Journal:

Crit Care Med

Year:

2015

Group:

,

Burry L, Cook D, Herridge M, Devlin JW, Fergusson D, Meade M, Steinberg M, Skrobik Y, Olafson K, Burns K, Dodek P, Granton J, Ferguson N, Jacka M, Tanios M, Fowler R, Reynolds S, Keenan S, Mallick R, Mehta S; SLEAP Investigators and the Canadian Critical Care Trials Group. Recall of ICU Stay in Patients Managed With a Sedation Protocol or a Sedation Protocol With Daily Interruption. Crit Care Med. 2015 Oct;43(10):2180-90. PMID: 26181221

Characteristics and Outcomes of Eligible Non-Enrolled Patients in a Mechanical Ventilation Trial of Acute Respiratory Distress Syndrome.

First Author:

Arabi YM

Journal:

Am J Respir Crit Care Med

Year:

2015

Group:

,

Arabi YM, Cook DJ, Zhou Q, Smith O, Hand L, Turgeon AF, Matte A, Mehta S, Graham R, Brierley K, Adhikari NK, Meade MO, Ferguson ND; Canadian Critical Care Trials Group. Characteristics and Outcomes of Eligible Non-Enrolled Patients in a Mechanical Ventilation Trial of Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2015 Jul 20. [Epub ahead of print] PMID: 26192398

Blood pressure targets for vasopressor therapy: a systematic review.

First Author:

D'Aragon F

Journal:

Shock

Year:

2015

Group:

D'Aragon F, Belley-Cote EP, Meade MO, Lauzier F, Adhikari NK, Briel M, Lalu M, Kanji S, Asfar P, Turgeon AF, Fox-Robichaud A, Marshall JC, Lamontagne F; Canadian Critical Care Trials Group. Blood pressure targets for vasopressor therapy: a systematic review. Shock. 2015 Jun;43(6):530-9. PMID: 25895147

Prevention of vitamin D deficiency in children following cardiac surgery: study protocol for a randomized controlled trial.

First Author:

McNally JD

Journal:

Trials

Year:

2015

Group:

, ,

McNally JD, O'Hearn K, Lawson ML, Maharajh G, Geier P, Weiler H, Redpath S, McIntyre L, Fergusson D, Menon K; Canadian Critical Care Trials Groups. Prevention of vitamin D deficiency in children following cardiac surgery: study protocol for a randomized controlled trial. Trials. 2015 Sep 9;16(1):402. PMID: 26353829

Competing Risk Analysis for Evaluation of Dalteparin Versus Unfractionated Heparin for Venous Thromboembolism in Medical-Surgical Critically Ill Patients.

First Author:

Li G

Journal:

Medicine

Year:

2015

Group:

Li G, Cook DJ, Levine MA, Guyatt G, Crowther M, Heels-Ansdell D, Holbrook A, Lamontagne F, Walter SD, Ferguson ND, Finfer S, Arabi YM, Bellomo R, Cooper DJ, Thabane L; PROTECT Investigators for the Canadian Critical Care Trials Group, and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Competing Risk Analysis for Evaluation of Dalteparin Versus Unfractionated Heparin for Venous Thromboembolism in Medical-Surgical Critically Ill Patients. Medicine (Baltimore). 2015 Sep;94(36):e1479. PMID: 26356708

1,25-Dihydroxyvitamin D Levels in Pediatric Intensive Care Units: Risk Factors and Association With Clinical Course.

First Author:

McNally JD

Journal:

J Clin Endocrinol Metab

Year:

2015

Group:

McNally JD, Menon K, Lawson ML, Williams K, Doherty DR.1,25-Dihydroxyvitamin D Levels in Pediatric Intensive Care Units: Risk Factors and Association With Clinical Course. J Clin Endocrinol Metab. 2015 Aug;100(8):2942-5.PMID: 26052726

Rapid normalization of vitamin D levels: a meta-analysis.

First Author:

McNally JD

Journal:

Pediatrics

Year:

2015

Group:

,

McNally JD, Iliriani K, Pojsupap S, Sampson M, O'Hearn K, McIntyre L, Fergusson D, Menon K. Rapid normalization of vitamin D levels: a meta-analysis. Pediatrics. 2015 Jan;135(1):e152-66. PMID: 25511115

Variations in the Operational Process of Withdrawal of Life-Sustaining Therapy.

First Author:

van Beinum A

Journal:

Crit Care Med

Year:

2015

Group:

van Beinum A, Hornby L, Ward R, Ramsay T, Dhanani S. Variations in the Operational Process of Withdrawal of Life-Sustaining Therapy. Crit Care Med. 2015 Oct;43(10):e450-7. PMID: 26121072

Enteral glutamine supplementation in critically ill patients: a systematic review and meta-analysis.

First Author:

van Zanten AR

Journal:

Crit Care

Year:

2015

Group:

van Zanten AR, Dhaliwal R, Garrel D, Heyland DK. Enteral glutamine supplementation in critically ill patients: a systematic review and meta-analysis. Crit Care. 2015 Aug 18;19:294. PMID: 26283217

Recovery after critical illness in patients aged 80 years or older: a multi-center prospective observational cohort study.

First Author:

Heyland DK

Journal:

Intensive Care Med.

Year:

2015

Group:

Heyland DK, Garland A, Bagshaw SM, Cook D, Rockwood K, Stelfox HT, Dodek P, Fowler RA, Turgeon AF, Burns K, Muscedere J, Kutsogiannis J, Albert M, Mehta S, Jiang X, Day AG. Recovery after critical illness in patients aged 80 years or older: a multi-center prospective observational cohort study. Intensive Care Med. 2015 Nov;41(11):1911-20. PMID: 26306719

Whole-blood neutrophil gelatinase-associated lipocalin to predict adverse events in acute kidney injury: A prospective observational cohort study.

First Author:

Rewa O

Journal:

J Crit Care

Year:

2015

Group:

Rewa O, Wald R, Adhikari NK, Hladunewich M, Lapinsky S, Muscedere J, Bagshaw SM, Smith OM, Lebovic G, Kuint R, Klein DJ. Whole-blood neutrophil gelatinase-associated lipocalin to predict adverse events in acute kidney injury: A prospective observational cohort study. J Crit Care. 2015 Dec;30(6):1359-64. PMID: 26421697