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The influence of corticosteroid treatment on the outcome of influenza A(H1N1pdm09)-related critical illness

First Author:

Delaney JW

Journal:

Crit Care

Year:

2016

Group:

, ,

Delaney JW, Pinto R, Long J, Lamontagne F, Adhikari NK, Kumar A, Marshall JC, Cook DJ, Jouvet P, Ferguson ND, Griesdale D, Burry LD, Burns KE, Hutchison J, Mehta S, Menon K, Fowler RA; Canadian Critical Care Trials Group H1N1 Collaborative. The influence of corticosteroid treatment on the outcome of influenza A(H1N1pdm09)-related critical illness. Crit Care. 2016 Mar 30;20(1):75. PMID: 27036638

CYCLE pilot: a protocol for a pilot randomised study of early cycle ergometry versus routine physiotherapy in mechanically ventilated patients

First Author:

Kho ME

Journal:

BMJ Open

Year:

2016

Group:

,

Kho, ME,  Molloy,AJ, Clarke, F, Herridge, MS, Koo, KKY, Rudkowski, J, Seely, AJE, Pellizzari, JR, Tarride, JE, Mourtzakis, M, Karachi, T, Cook, DJ, the Canadian Critical Care Trials Group. CYCLE pilot: a protocol for a pilot randomised study of early cycle ergometry versus routine physiotherapy in mechanically ventilated patients. BMJ Open. 2016 Apr 8;6(4):e011659. PMID: 27059469

Predicting Performance Status 1 Year After Critical Illness in Patients 80 Years or Older: Development of a Multivariable Clinical Prediction Model.

First Author:

Heyland DK

Journal:

Crit Care Med

Year:

2016

Group:

Heyland DK, Stelfox HT, Garland A, Cook D, Dodek P, Kutsogiannis J, Jiang X, Turgeon AF, Day AG; Canadian Critical Care Trials Group and the Canadian Researchers at the End of Life Network. Predicting Performance Status 1 Year After Critical Illness in Patients 80 Years or Older: Development of a Multivariable Clinical Prediction Model. Crit Care Med. 2016 Sep;44(9):1718-26. PMID: 27075141

Recovery and outcomes after the acute respiratory distress syndrome (ARDS) in patients and their family caregivers.

First Author:

Herridge MS

Journal:

Intensive Care Med.

Year:

2016

Group:

Herridge MS, Moss M, Hough CL, Hopkins RO, Rice TW, Bienvenu OJ, Azoulay E.Recovery and outcomes after the acute respiratory distress syndrome (ARDS) in patients and their family caregivers. Intensive Care Med. 2016 May;42(5):725-38. PMID: 27025938

Steroids in fluid and/or vasoactive infusion dependent pediatric shock: study protocol for a randomized controlled trial.

First Author:

O'Hearn K

Journal:

Trials

Year:

2016

Group:

, ,

O'Hearn K, McNally D, Choong K, Acharya A, Wong HR, Lawson M, Ramsay T, McIntyre L, Gilfoyle E, Tucci M, Wensley D, Gottesman R, Morrison G, Menon K; Canadian Critical Care Trials Group. Steroids in fluid and/or vasoactive infusion dependent pediatric shock: study protocol for a randomized controlled trial. Trials. 2016 May 6;17(1):238. PMID: 27153945

One-Year Outcomes in Caregivers of Critically Ill Patients

First Author:

Cameron JI

Journal:

N Engl J Med

Year:

2016

Group:

,

Cameron JI, Chu LM, Matte A, Tomlinson G, Chan L, Thomas C, Friedrich JO, Mehta S, Lamontagne F, Levasseur M, Ferguson ND, Adhikari NK, Rudkowski JC, Meggison H, Skrobik Y, Flannery J, Bayley M, Batt J, dos Santos C, Abbey SE, Tan A, Lo V, Mathur S, Parotto M, Morris D, Flockhart L, Fan E, Lee CM, Wilcox ME, Ayas N, Choong K, Fowler R, Scales DC, Sinuff T, Cuthbertson BH, Rose L, Robles P, Burns S, Cypel M, Singer L, Chaparro C, Chow CW, Keshavjee S, Brochard L, Hébert P, Slutsky AS, Marshall JC, Cook D, Herridge MS; RECOVER Program Investigators (Phase 1: towards RECOVER); Canadian Critical Care Trials Group. One-Year Outcomes in Caregivers of Critically Ill Patients. N Engl J Med. 2016 May 12;374(19):1831-41. PMID: 27168433

Serum Biomarkers Help Predict Attention Problems in Critically Ill Children With Traumatic Brain Injury.

First Author:

Wilkinson AA

Journal:

Pediatr Crit Care Med.

Year:

2016

Group:

,

Wilkinson AA, Simic N, Frndova H, Taylor MJ, Choong K, Fraser D, Campbell C, Dhanani S, Kuehn S, Beauchamp MH, Farrell C, Anderson V, Guerguerian AM, Dennis M, Schachar R, Hutchison JS; Attention and Traumatic Brain Injury Investigators, the Canadian Critical Care Trials Group, and the Canadian Critical Care Translational Biology Group. Serum Biomarkers Help Predict Attention Problems in Critically Ill Children With Traumatic Brain Injury. Pediatr Crit Care Med. 2016 Jul;17(7):638-48. PMID: 27167007

Multicountry survey of emergency and critical care medicine physicians' fluid resuscitation practices for adult patients with early septic shock.

First Author:

McIntyre L

Journal:

BMJ Open

Year:

2016

Group:

McIntyre L, Rowe BH, Walsh TS, Gray A, Arabi Y, Perner A, Gordon A, Marshall J, Cook D, Fox-Robichaud A, Bagshaw SM, Green R, Schweitzer I, Turgeon A, Zarychanski R, English S, Chassé M, Stiell I, Fergusson D; Canadian Critical Care Trials Group. Multicountry survey of emergency and critical care medicine physicians' fluid resuscitation practices for adult patients with early septic shock. BMJ Open. 2016 Jul 7;6(7). PMID: 27388345

Risk factors for mortality in patients admitted to intensive care units with pneumonia.

First Author:

Li G

Journal:

Respir Res.

Year:

2016

Group:

Li G, Cook DJ, Thabane L, Friedrich JO, Crozier TM, Muscedere J, Granton J, Mehta S, Reynolds SC, Lopes RD, Francois L, Freitag AP, Levine MA; PROTECT Investigators for the Canadian Critical Care Trials Group, and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Risk factors for mortality in patients admitted to intensive care units with pneumonia. Respir Res. 2016 Jul 11;17(1):80. PMID: 27401184

Survey of Sedation and Analgesia Practice Among Canadian Pediatric Critical Care Physicians

First Author:

Garcia Guerra G

Journal:

Pediatr Crit Care Med.

Year:

2016

Group:

, ,

Guerra GG, Joffe AR, Cave D, Duff J, Duncan S, Sheppard C, Tawfik G, Hartling L, Jou H, Vohra S; Sedation Withdrawal and Analgesia Team, and the Canadian Critical Care Trials Group. Survey of Sedation and Analgesia Practice Among Canadian Pediatric Critical Care Physicians. Pediatr Crit Care Med. 2016 Sep;17(9):823-30. PMID: 27467012

Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial-PROSPECT: a pilot trial.

First Author:

Cook DJ

Journal:

Trials

Year:

2016

Group:

Cook DJ, Johnstone J, Marshall JC, Lauzier F, Thabane L, Mehta S, Dodek PM, McIntyre L, Pagliarello J, Henderson W, Taylor RW, Cartin-Ceba R, Golan E, Herridge M, Wood G, Ovakim D, Karachi T, Surette MG, Bowdish DM, Lamarche D, Verschoor CP, Duan EH, Heels-Ansdell D, Arabi Y, Meade M; PROSPECT Investigators and the Canadian Critical Care Trials Group. Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial-PROSPECT: a pilot trial. Trials. 2016 Aug 2;17:377. PMID: 27480757

Variation in diurnal sedation in mechanically ventilated patients who are managed with a sedation protocol alone or a sedation protocol and daily interruption.

First Author:

Mehta S

Journal:

Crit Care

Year:

2016

Group:

,

Mehta S, Meade M, Burry L, Mallick R, Katsios C, Fergusson D, Dodek P, Burns K, Herridge M, Devlin JW, Tanios M, Fowler R, Jacka M, Skrobik Y, Olafson K, Cook D; SLEAP Investigators and the Canadian Critical Care Trials Group. Variation in diurnal sedation in mechanically ventilated patients who are managed with a sedation protocol alone or a sedation protocol and daily interruption. Crit Care. 2016 Aug 1;20(1):233. PMID: 27480314

The Development of a Critical Care Resident Research Curriculum: A Needs Assessment.

First Author:

Jain S

Journal:

Can Respir J.

Year:

2016

Group:

,

Jain S, Menon K, Piquette D, Gottesman R, Hutchison J, Gilfoyle E, Group CC. The Development of a Critical Care Resident Research Curriculum: A Needs Assessment. Can Respir J. 2016; Epub 2016 Aug 16. PMID: 27610029

A trial to determine whether septic shock-reversal is quicker in pediatric patients randomized to an early goal-directed fluid-sparing strategy versus usual care (SQUEEZE): study protocol for a pilot randomized controlled trial.

First Author:

Parker MJ

Journal:

Trials

Year:

2016

Group:

, ,

Parker MJ, Thabane L, Fox-Robichaud A, Liaw P, Choong K; Canadian Critical Care Trials Group and the Canadian Critical Care Translational Biology Group.A trial to determine whether septic shock-reversal is quicker in pediatric patients randomized to an early goal-directed fluid-sparing strategy versus usual care (SQUEEZE): study protocol for a pilot randomized controlled trial. Trials. 2016 Nov 22;17(1):556. PMID: 27876084

Aneurysmal SubArachnoid Hemorrhage-Red Blood Cell Transfusion And Outcome (SAHaRA): a pilot randomised controlled trial protocol.

First Author:

English SW

Journal:

BMJ Open

Year:

2016

Group:

English SW, Fergusson D, Chassé M, Turgeon AF, Lauzier F, Griesdale D, Algird A, Kramer A, Tinmouth A, Lum C, Sinclair J, Marshall S, Dowlatshahi D, Boutin A, Pagliarello G, McIntyre LA; Canadian Critical Care Trials Group. Aneurysmal SubArachnoid Hemorrhage-Red Blood Cell Transfusion And Outcome (SAHaRA): a pilot randomised controlled trial protocol. BMJ Open. 2016 Dec 7;6(12):e012623. PMID: 27927658

The Effect of Inadequate Initial Empiric Antimicrobial Treatment on Mortality in Critically Ill Patients with Bloodstream Infections: A Multi-Centre Retrospective Cohort Study.

First Author:

Savage RD

Journal:

PLoS One

Year:

2016

Group:

Savage RD, Fowler RA, Rishu AH, Bagshaw SM, Cook D, Dodek P, Hall R, Kumar A, Lamontagne F, Lauzier F, Marshall J, Martin CM, McIntyre L, Muscedere J, Reynolds S, Stelfox HT, Daneman N. The Effect of Inadequate Initial Empiric Antimicrobial Treatment on Mortality in Critically Ill Patients with Bloodstream Infections: A Multi-Centre Retrospective Cohort Study. PLoS One. 2016 May 6;11(5):e0154944. PMID:27152615

TryCYCLE: A Prospective Study of the Safety and Feasibility of Early In-Bed Cycling in Mechanically Ventilated Patients

First Author:

Kho ME

Journal:

PLoS One

Year:

2016

Group:

,

Kho ME, Molloy AJ, Clarke FJ, Ajami D, McCaughan M, Obrovac K, Murphy C, Camposilvan L, Herridge MS, Koo KK, Rudkowski J, Seely AJ, Zanni JM, Mourtzakis M, Piraino T, Cook DJ; Canadian Critical Care Trials Group.TryCYCLE: A Prospective Study of the Safety and Feasibility of Early In-Bed Cycling in Mechanically Ventilated Patients. PLoS One. 2016 Dec 28;11(12). PMID: 28030555

Re-evaluating the Inhibition of Stress Erosions (REVISE): a protocol for pilot randomized controlled trial.

First Author:

Alhazzani W

Journal:

Ann Saudi Med.

Year:

2016

Group:

,

Alhazzani W, Guyatt G, Marshall JC, Hall R, Muscedere J, Lauzier F, Thabane L, Alshahrani M, English SW, Arabi YM, Deane AM, Karachi T, Rochwerg B, Finfer S, Daneman N, Zytaruk N, Heel-Ansdell D, Cook D, Of OB. Re-evaluating the Inhibition of Stress Erosions (REVISE): a protocol for pilot randomized controlled trial. Ann Saudi Med. 2016 Nov-Dec;36(6):427-433. PMID: 27920416

The RECOVER Program: Disability Risk Groups & One Year Outcome after ≥ 7 Days of Mechanical Ventilation.

First Author:

Herridge MS

Journal:

Am J Respir Crit Care Med

Year:

2016

Group:

Herridge MS, Chu LM, Matte A, Tomlinson G, Chan L, Thomas C, Friedrich JO, Mehta S, Lamontagne F, Levasseur M, Ferguson ND, Adhikari NK, Rudkowski JC, Meggison H, Skrobik Y, Flannery J, Bayley M, Batt J, Dos Santos C, Abbey SE, Tan A, Lo V, Mathur S, Parotto M, Morris D, Flockhart L, Fan E, Lee CM, Wilcox ME, Ayas N, Choong K, Fowler R, Scales DC, Sinuff T, Cuthbertson BH, Rose L, Robles P, Burns S, Cypel M, Singer L, Chaparro C, Chow CW, Keshavjee S, Brochard L, Hebert P, Slutsky AS, Marshall JC, Cook D, Cameron JI; RECOVER Program Investigators (Phase 1: towards RECOVER) and the Canadian Critical Care Trials Group. The RECOVER Program: Disability Risk Groups & One Year Outcome after ≥ 7 Days of Mechanical Ventilation. Am J Respir Crit Care Med. 2016 Mar 14. [Epub ahead of print] PMID: 26974173

Early mobilization of critically ill adults: a survey of knowledge, perceptions and practices of Canadian physicians and physiotherapists.

First Author:

Koo KK

Journal:

CMAJ Open

Year:

2016

Group:

Koo KK, Choong K, Cook DJ, Herridge M, Newman A, Lo V, Guyatt G, Priestap F, Campbell E, Burns KE, Lamontagne F, Meade MO; Canadian Critical Care Trials Group. Early mobilization of critically ill adults: a survey of knowledge, perceptions and practices of Canadian physicians and physiotherapists. CMAJ Open. 2016 Aug 18;4(3):E448-E454. PMID: 27730109

Pandemic influenza 2009: Impact of vaccination coverage on critical illness in children, a Canada and France observational study

First Author:

Fléchelles, O

Journal:

World J Clin Pediatr

Year:

2016

Group:

Fléchelles, O, Brissaud, O, Fowler, R, Ducruet, T, Jouvet, P. The Pediatric Canadian Critical Care Trials Group H1N1 Collaborative and Groupe Francophone de Réanimation et Urgences Pédiatriques. Pandemic influenza 2009: Impact of vaccination coverage on critical illness in children, a Canada and France observational study. World J Clin Pediatr 2016 November 8; 5(4): 374-382

Prevalence, risk factors and outcomes associated with physical restraint use in mechanically ventilated adults

First Author:

Rose, L

Journal:

J Crit Care

Year:

2016

Group:

Rose L, Burry L, Mallick R, Luk E, Cook DJ, Fergusson ND, Meade M, Herridge M, Dodek PE, Burns KE, Granton J, Ferguson ND, Devlin J, Steinberg M, Keenan S, Reynolds S, Tanios M, Fowler R, Jacka M, Olafson K, Skrobik Y, Mehta S for the SLEAP investigators and Canadian Critical Care Trials Group. Prevalence, risk factors and outcomes associated with physical restraint use in mechanically ventilated adults. J Crit Care. 2016 Feb;31(1):31-5.

Prevalence, Risk Factors, and Outcomes of Delirium in Mechanically Ventilated Adults.

First Author:

Mehta S

Journal:

Crit Care Med

Year:

2015

Group:

,

Mehta S, Cook D, Devlin JW, Skrobik Y, Meade M, Fergusson D, Herridge M, Steinberg M, Granton J, Ferguson N, Tanios M, Dodek P, Fowler R, Burns K, Jacka M, Olafson K, Mallick R, Reynolds S, Keenan S, Burry L; for the SLEAP Investigators and the Canadian Critical Care Trials Group. Prevalence, Risk Factors, and Outcomes of Delirium in Mechanically Ventilated Adults.Crit Care Med. 2015, 43(3):557-66. PMID: 25493968

Failure of Anticoagulant Thromboprophylaxis: Risk Factors in Medical-Surgical Critically Ill Patients.

First Author:

Lim W

Journal:

Crit Care Med

Year:

2015

Group:

Lim W, Meade M, Lauzier F, Zarychanski R, Mehta S, Lamontagne F, Dodek P, McIntyre L, Hall R, Heels-Ansdell D, Fowler R, Pai M, Guyatt G, Crowther MA, Warkentin TE, Devereaux PJ, Walter SD, Muscedere J, Herridge M, Turgeon AF, Geerts W, Finfer S, Jacka M, Berwanger O, Ostermann M, Qushmaq I, Friedrich JO, Cook DJ; for the PROphylaxis for ThromboEmbolism in Critical Care Trial Investigators, the Canadian Critical Care Trials Group, and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Failure of Anticoagulant Thromboprophylaxis: Risk Factors in Medical-Surgical Critically Ill Patients.Crit Care Med. 2015; 43(2):401-10. PMID: 25474533