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Frequency of Screening and SBT Technique Trial - North American Weaning Collaboration (FAST-NAWC): a protocol for a multicenter, factorial randomized trial.

First Author:

Burns KEA

Journal:

Trials

Year:

2019

Group:

Burns KEA, Rizvi L, Cook DJ, Seely AJE, Rochwerg B, Lamontagne F, Devlin JW, Dodek P, Mayette M, Tanios M, Gouskos A, Kay P, Mitchell S, Kiedrowski KC, Hill NS; Canadian Critical Care Trials Group. Frequency of Screening and SBT Technique Trial - North American Weaning Collaboration (FAST-NAWC): a protocol for a multicenter, factorial randomized trial Trials. 2019 Oct 11;20(1):587. PMID: 31604480

Effect of Fresh vs Standard-issue Red Blood Cell Transfusions on Multiple Organ Dysfunction Syndrome in Critically Ill Pediatric Patients: A Randomized Clinical Trial.

First Author:

Spinella PC

Journal:

JAMA

Year:

2019

Group:

,

Spinella PC, Tucci M, Fergusson DA, Lacroix J, Hébert PC, Leteurtre S, Schechtman KB, Doctor A, Berg RA, Bockelmann T, Caro JJ, Chiusolo F, Clayton L, Cholette JM, Guerra GG, Josephson CD, Menon K, Muszynski JA, Nellis ME, Sarpal A, Schafer S, Steiner ME, Turgeon AF; ABC-PICU Investigators, the Canadian Critical Care Trials Group, the Pediatric Acute Lung Injury and Sepsis Investigators Network, the BloodNet Pediatric Critical Care Blood Research Network, and the Groupe Francophone de Réanimation et Urgences P. Effect of Fresh vs Standard-issue Red Blood Cell Transfusions on Multiple Organ Dysfunction Syndrome in Critically Ill Pediatric Patients: A Randomized Clinical Trial. JAMA. 2019 Dec 10;322(22):2179-2190. PMID: 31821429

Exploring the experiences and perspectives of substitute decision-makers involved in decisions about deceased organ donation: a qualitative study protocol.

First Author:

Crawshaw J

Journal:

BMJ Open

Year:

2019

Group:

Crawshaw J, Presseau J, van Allen Z, Pinheiro Carvalho L, Jordison K, English S, Fergusson DA, Lauzier F, Turgeon AF, Sarti AJ, Martin C, D'Aragon F, Li AH, Knoll G, Ball I, Brehaut J, Burns KEA, Fortin MC, Weiss M, Meade M, Marsolais P, Shemie S, Zaabat S, Dhanani S, Kitto SC, Chassé M; Canadian Donation and Transplantation Research Program and the Canadian Critical Care Trials Group. Exploring the experiences and perspectives of substitute decision-makers involved in decisions about deceased organ donation: a qualitative study protocol. BMJ Open. 2019 Dec 23;9(12):e034594. PMID: 31874899

Cellular Immunotherapy for Septic Shock (CISS): A Phase I Clinical Trial.

First Author:

McIntyre LA

Journal:

Am J Respir Crit Care Med.

Year:

2018

Group:

, ,

McIntyre LA, Stewart DJ, Mei SHJ, Courtman D, Watpool I, Granton J, Marshall J, Dos Santos C, Walley KR, Winston BW, Schlosser K, Fergusson DA; Canadian Critical Care Trials Group and the Canadian Critical Care Translational Biology Group. Cellular Immunotherapy for Septic Shock (CISS): A Phase I Clinical Trial. Am J Respir Crit Care Med. 2018 Feb 1;197(3):337-347. PMID: 28960096

The Young Investigator Retreat of the Canadian Critical Care Trials Group: mentorship and self-discovery.

First Author:

Ball IM

Journal:

Can J Anaesth.

Year:

2018

Group:

, ,

Ball IM, Burry L, Dodek P, Hutchison JS, Leigh JP, McCredie V, Murthy S, Rochwerg B, Cook D; Canadian Critical Care Trials Group and the Canadian Critical Care Translational Biology Group. The Young Investigator Retreat of the Canadian Critical Care Trials Group: mentorship and self-discovery. Can J Anaesth. 2018 Mar;65(3):239-245. PMID: 29150787

Chloride and Other Electrolyte Concentrations in Commonly Available 5% Albumin Products.

First Author:

Lai AT

Journal:

Crit Care Med

Year:

2018

Group:

Lai AT, Zeller MP, Millen T, Kavsak P, Szczeklik W, Elahie A, Alhazzani W, D'Aragon F, Jaeschke R, Lamontagne F, Karachi T, Cook D, Meade M, Rochwerg B; Canadian Critical Care Trials Group. Chloride and Other Electrolyte Concentrations in Commonly Available 5% Albumin Products. Crit Care Med. 2018 Apr;46(4):e326-e329. PMID: 29293151

Prospective cohort study on noise levels in a pediatric cardiac intensive care unit.

First Author:

Garcia Guerra G

Journal:

J Crit Care

Year:

2018

Group:

, ,

Garcia Guerra G, Joffe AR, Sheppard C, Pugh J, Moez EK, Dinu IA, Jou H, Hartling L, Vohra S; Sedation Withdrawal and Analgesia Team (SWAT); Canadian Critical Care Trials Group (CCCTG). Prospective cohort study on noise levels in a pediatric cardiac intensive care unit.  J Crit Care. 2018 Apr;44:318-322. PMID: 29274594

Effect of a Pediatric Early Warning System on All-Cause Mortality in Hospitalized Pediatric Patients: The EPOCH Randomized Clinical Trial.

First Author:

Parshuram CS

Journal:

JAMA

Year:

2018

Group:

,

Parshuram CS, Dryden-Palmer K, Farrell C, Gottesman R, Gray M, Hutchison JS, Helfaer M, Hunt EA, Joffe AR, Lacroix J, Moga MA, Nadkarni V, Ninis N, Parkin PC, Wensley D, Willan AR, Tomlinson GA; Canadian Critical Care Trials Group and the EPOCH Investigators. Effect of a Pediatric Early Warning System on All-Cause Mortality in Hospitalized Pediatric Patients: The EPOCH Randomized Clinical Trial. JAMA. 2018 Mar 13;319(10):1002-1012. PMID: 29486493

Assessing frailty in the intensive care unit: A reliability and validity study

First Author:

Shears, M

Journal:

J Crit Care

Year:

2018

Group:

Shears M, Takaoka A, Rochwerg B, Bagshaw SM, Johnstone J, Holding A, Tharmalingam S, Millen T, Clarke F, Rockwood K, Li G, Thabane L, Muscedere J, Stelfox HT, Cook DJ; Canadian Critical Care Trials Group. Assessing frailty in the intensive care unit: A reliability and validity study. J Crit Care. 2018 Feb 8;45:197-203. PMID: 29574340

Efficacy and safety of stress ulcer prophylaxis in critically ill patients: a network meta-analysis of randomized trials.

First Author:

Alhazzani W

Journal:

Intensive Care Med.

Year:

2018

Group:

Alhazzani W, Alshamsi F, Belley-Cote E, Heels-Ansdell D, Brignardello-Petersen R, Alquraini M, Perner A, Møller MH, Krag M, Almenawer S, Rochwerg B, Dionne J, Jaeschke R, Alshahrani M, Deane A, Perri D, Thebane L, Al-Omari A, Finfer S, Cook D, Guyatt G. Efficacy and safety of stress ulcer prophylaxis in critically ill patients: a network meta-analysis of randomized trials. Intensive Care Med. 2018 Jan;44(1):1-11. PMID: 29199388

Age of transfused blood in critically ill adult trauma patients: a prespecified nested analysis of the Age of Blood Evaluation randomized trial.

First Author:

Green RS

Journal:

Transfusion

Year:

2018

Group:

,

Green RS, Erdogan M, Lacroix J, Hébert PC, Tinmouth AT, Sabri E, Zhang T, Fergusson DA, Turgeon AF; ABLE Investigators and the Canadian Critical Care Trials Group. Age of transfused blood in critically ill adult trauma patients: a prespecified nested analysis of the Age of Blood Evaluation randomized trial. Transfusion. 2018 Aug;58(8):1846-1854. PMID: 29672869

Intensity of care and withdrawal of life-sustaining therapies in severe traumatic brain injury patients: a post-hoc analysis of a multicentre retrospective cohort study.

First Author:

Gerges PRA

Journal:

Can J Anaesth

Year:

2018

Group:

Gerges PRA, Moore L, Léger C, Lauzier F, Shemilt M, Zarychanski R, Scales DC, Burns KEA, Bernard F, Zygun D, Neveu X, Turgeon AF; Canadian Critical Care Trials Group. Intensity of care and withdrawal of life-sustaining therapies in severe traumatic brain injury patients: a post-hoc analysis of a multicentre retrospective cohort study. Can J Anaesth. 2018 Sep;65(9):996-1003. PMID: 29949093

Random serum free cortisol and total cortisol measurements in pediatric septic shock.

First Author:

Menon K

Journal:

J Pediatr Endocrinol Metab

Year:

2018

Group:

,

Menon K, McNally D, Acharya A, O'Hearn K, Choong K, Wong HR, McIntyre L, Lawson M; Canadian Critical Care Trials Group. Random serum free cortisol and total cortisol measurements in pediatric septic shock. J Pediatr Endocrinol Metab. 2018 Jul 26;31(7):757-762. doi: 10.1515/jpem-2018-0027. PMID: 29953408

Anemia prevalence and incidence and red blood cell transfusion practices in aneurysmal subarachnoid hemorrhage: results of a multicenter cohort study.

First Author:

English SW

Journal:

Crit Care.

Year:

2018

Group:

English SW, Chassé M, Turgeon AF, Lauzier F, Griesdale D, Garland A, Fergusson D, Zarychanski R, van Walraven C, Montroy K, Ziegler J, Dupont-Chouinard R, Carignan R, Dhaliwal A, Mallick R, Sinclair J, Boutin A, Pagliarello G, Tinmouth A, McIntyre L; Canadian Critical Care Trials Group. Anemia prevalence and incidence and red blood cell transfusion practices in aneurysmal subarachnoid hemorrhage: results of a multicenter cohort study. Crit Care. 2018 Jul 4;22(1):169. PMID: 29973245

Hamilton-DONATE: a city-wide pilot observational study of the ICU management of deceased organ donors.

First Author:

D'Aragon F

Journal:

Can J Anaesth

Year:

2018

Group:

D'Aragon F, Cook D, Dhanani S, Ribic C, Burns KEA, Akhtar A, Hand L, Arseneau E, Cupido C, Whittigham H, Healey A, Frenette AJ, Lamontagne F, Meade MO; Canadian Critical Care Trials Group and the Canadian National Transplant Research Program. Hamilton-DONATE: a city-wide pilot observational study of the ICU management of deceased organ donors. Can J Anaesth. 2018 Oct;65(10):1110-1119. PMID: 29987806

The age of blood in pediatric intensive care units (ABC PICU): study protocol for a randomized controlled trial.

First Author:

Tucci M

Journal:

Trials.

Year:

2018

Group:

,

Tucci M, Lacroix J, Fergusson D, Doctor A, Hébert P, Berg RA, Caro J, Josephson CD, Leteurtre S, Menon K, Schechtman K, Steiner ME, Turgeon AF, Clayton L, Bockelmann T, Spinella PC; Canadian Critical Care Trials Group; Pediatric Critical Care Blood Research Network (BloodNet); Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. The age of blood in pediatric intensive care units (ABC PICU): study protocol for a randomized controlled trial. Trials. 2018 Jul 28;19(1):404. PMID: 30055634

The Canadian Traumatic Brain Injury Research Consortium: Epitomizing Collaborative Research in Canada.

First Author:

Hutchison JS

Journal:

J Neurotrauma.

Year:

2018

Group:

,

Hutchison JS, Emery C, Gagnon I, Léger C, Riopelle R, Wellington C, Wilson E, Turgeon AF. The Canadian Traumatic Brain Injury Research Consortium: Epitomizing Collaborative Research in Canada. J Neurotrauma. 2018 Aug 15;35(16):1858-1863. PMID: 30074867

Robotic technology provides objective and quantifiable metrics of neurocognitive functioning in survivors of critical illness:A feasibility study.

First Author:

Wood MD

Journal:

J Crit Care

Year:

2018

Group:

Wood MD, Maslove DM, Muscedere J, Scott SH, Boyd JG; Canadian Critical Care Trials Group. Robotic technology provides objective and quantifiable metrics of neurocognitive functioning in survivors of critical illness:A feasibility study. J Crit Care. 2018 Sep 12;48:228-236. PMID: 30243203

Microbial dysbiosis and mortality during mechanical ventilation: a prospective observational study.

First Author:

Lamarche D

Journal:

Respir Res.

Year:

2018

Group:

, ,

Lamarche D, Johnstone J, Zytaruk N, Clarke F, Hand L, Loukov D, Szamosi JC, Rossi L, Schenck LP, Verschoor CP, McDonald E, Meade MO, Marshall JC, Bowdish DME, Karachi T, Heels-Ansdell D, Cook DJ, Surette MG; PROSPECT Investigators; Canadian Critical Care Trials Group; Canadian Critical Care Translational Biology Group. Microbial dysbiosis and mortality during mechanical ventilation: a prospective observational study. Respir Res. 2018 Dec 7;19(1):245. PMID: 30526610

FLUID trial: a protocol for a hospital-wide open-label cluster crossover pragmatic comparative effectiveness randomised pilot trial.

First Author:

McIntyre L

Journal:

BMJ Open

Year:

2018

Group:

McIntyre L, Taljaard M, McArdle T, Fox-Robichaud A, English SW, Martin C, Marshall J, Menon K, Muscedere J, Cook DJ, Weijer C, Saginur R, Maybee A, Iyengar A, Forster A, Graham ID, Hawken S, McCartney C, Seely AJ, Stiell IG, Thavorn K, Fergusson DA. FLUID trial: a protocol for a hospital-wide open-label cluster crossover pragmatic comparative effectiveness randomised pilot trial. BMJ Open. 2018 Aug 23;8(8):e022780. PMID: 30139908

International Practice Variation in Weaning Critically Ill Adults from Invasive Mechanical Ventilation.

First Author:

Burns KEA

Journal:

Ann Am Thorac Soc.

Year:

2018

Group:

Burns KEA, Raptis S, Nisenbaum R, Rizvi L, Jones A, Bakshi J, Tan W, Meret A, Cook DJ, Lellouche F, Epstein SK, Gattas D, Kapadia FN, Villar J, Brochard L, Lessard MR, Meade MO. International Practice Variation in Weaning Critically Ill Adults from Invasive Mechanical Ventilation. Ann Am Thorac Soc. 2018 Apr;15(4):494-502. PMID: 29509509

Pooled analysis of higher versus lower blood pressure targets for vasopressor therapy septic and vasodilatory shock.

First Author:

Lamontagne F

Journal:

Intensive Care Med.

Year:

2018

Group:

Lamontagne F, Day AG, Meade MO, Cook DJ, Guyatt GH, Hylands M, Radermacher P, Chrétien JM, Beaudoin N, Hébert P, D'Aragon F, Meziani F, Asfar P. Pooled analysis of higher versus lower blood pressure targets for vasopressor therapy septic and vasodilatory shock. Intensive Care Med. 2018 Jan;44(1):12-21. PMID: 29260272

A Multicenter Study of Surrogate Decision-Makers Experiences in Being Approached for Consent for Patient Participation in Research.

First Author:

Burns KEA

Journal:

Ann Am Thorac Soc.

Year:

2017

Group:

,

Burns KEA, Juando Prats C, Maione M, Lanceta M, Zubrinich C Md, Jeffs L PhD, Smith OM; Canadian Critical Care Trials Group. A Multicenter Study of Surrogate Decision-Makers Experiences in Being Approached for Consent for Patient Participation in Research. Ann Am Thorac Soc. 2017 Feb;14(2):238-245. PMID: 27849142

Airway Management Strategies for Brain-injured Patients Meeting Standard Criteria to Consider Extubation. A Prospective Cohort Study.

First Author:

McCredie VA

Journal:

Ann Am Thorac Soc

Year:

2017

Group:

,

McCredie VA, Ferguson ND, Pinto RL, Adhikari NK, Fowler RA, Chapman MG, Burrell A, Baker AJ, Cook DJ, Meade MO, Scales DC; Canadian Critical Care Trials Group.Airway Management Strategies for Brain-injured Patients Meeting Standard Criteria to Consider Extubation. A Prospective Cohort Study. Ann Am Thorac Soc. 2017 Jan;14(1):85-93. PMID: 27870576