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Intensity of care and withdrawal of life-sustaining therapies in severe traumatic brain injury patients: a post-hoc analysis of a multicentre retrospective cohort study.

First Author:

Gerges PRA

Journal:

Can J Anaesth

Year:

2018

Group:

Gerges PRA, Moore L, Léger C, Lauzier F, Shemilt M, Zarychanski R, Scales DC, Burns KEA, Bernard F, Zygun D, Neveu X, Turgeon AF; Canadian Critical Care Trials Group. Intensity of care and withdrawal of life-sustaining therapies in severe traumatic brain injury patients: a post-hoc analysis of a multicentre retrospective cohort study. Can J Anaesth. 2018 Sep;65(9):996-1003. PMID: 29949093

Random serum free cortisol and total cortisol measurements in pediatric septic shock.

First Author:

Menon K

Journal:

J Pediatr Endocrinol Metab

Year:

2018

Group:

,

Menon K, McNally D, Acharya A, O'Hearn K, Choong K, Wong HR, McIntyre L, Lawson M; Canadian Critical Care Trials Group. Random serum free cortisol and total cortisol measurements in pediatric septic shock. J Pediatr Endocrinol Metab. 2018 Jul 26;31(7):757-762. doi: 10.1515/jpem-2018-0027. PMID: 29953408

Anemia prevalence and incidence and red blood cell transfusion practices in aneurysmal subarachnoid hemorrhage: results of a multicenter cohort study.

First Author:

English SW

Journal:

Crit Care.

Year:

2018

Group:

English SW, Chassé M, Turgeon AF, Lauzier F, Griesdale D, Garland A, Fergusson D, Zarychanski R, van Walraven C, Montroy K, Ziegler J, Dupont-Chouinard R, Carignan R, Dhaliwal A, Mallick R, Sinclair J, Boutin A, Pagliarello G, Tinmouth A, McIntyre L; Canadian Critical Care Trials Group. Anemia prevalence and incidence and red blood cell transfusion practices in aneurysmal subarachnoid hemorrhage: results of a multicenter cohort study. Crit Care. 2018 Jul 4;22(1):169. PMID: 29973245

Hamilton-DONATE: a city-wide pilot observational study of the ICU management of deceased organ donors.

First Author:

D'Aragon F

Journal:

Can J Anaesth

Year:

2018

Group:

D'Aragon F, Cook D, Dhanani S, Ribic C, Burns KEA, Akhtar A, Hand L, Arseneau E, Cupido C, Whittigham H, Healey A, Frenette AJ, Lamontagne F, Meade MO; Canadian Critical Care Trials Group and the Canadian National Transplant Research Program. Hamilton-DONATE: a city-wide pilot observational study of the ICU management of deceased organ donors. Can J Anaesth. 2018 Oct;65(10):1110-1119. PMID: 29987806

The age of blood in pediatric intensive care units (ABC PICU): study protocol for a randomized controlled trial.

First Author:

Tucci M

Journal:

Trials.

Year:

2018

Group:

,

Tucci M, Lacroix J, Fergusson D, Doctor A, Hébert P, Berg RA, Caro J, Josephson CD, Leteurtre S, Menon K, Schechtman K, Steiner ME, Turgeon AF, Clayton L, Bockelmann T, Spinella PC; Canadian Critical Care Trials Group; Pediatric Critical Care Blood Research Network (BloodNet); Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. The age of blood in pediatric intensive care units (ABC PICU): study protocol for a randomized controlled trial. Trials. 2018 Jul 28;19(1):404. PMID: 30055634

The Canadian Traumatic Brain Injury Research Consortium: Epitomizing Collaborative Research in Canada.

First Author:

Hutchison JS

Journal:

J Neurotrauma.

Year:

2018

Group:

,

Hutchison JS, Emery C, Gagnon I, Léger C, Riopelle R, Wellington C, Wilson E, Turgeon AF. The Canadian Traumatic Brain Injury Research Consortium: Epitomizing Collaborative Research in Canada. J Neurotrauma. 2018 Aug 15;35(16):1858-1863. PMID: 30074867

Robotic technology provides objective and quantifiable metrics of neurocognitive functioning in survivors of critical illness:A feasibility study.

First Author:

Wood MD

Journal:

J Crit Care

Year:

2018

Group:

Wood MD, Maslove DM, Muscedere J, Scott SH, Boyd JG; Canadian Critical Care Trials Group. Robotic technology provides objective and quantifiable metrics of neurocognitive functioning in survivors of critical illness:A feasibility study. J Crit Care. 2018 Sep 12;48:228-236. PMID: 30243203

Microbial dysbiosis and mortality during mechanical ventilation: a prospective observational study.

First Author:

Lamarche D

Journal:

Respir Res.

Year:

2018

Group:

, ,

Lamarche D, Johnstone J, Zytaruk N, Clarke F, Hand L, Loukov D, Szamosi JC, Rossi L, Schenck LP, Verschoor CP, McDonald E, Meade MO, Marshall JC, Bowdish DME, Karachi T, Heels-Ansdell D, Cook DJ, Surette MG; PROSPECT Investigators; Canadian Critical Care Trials Group; Canadian Critical Care Translational Biology Group. Microbial dysbiosis and mortality during mechanical ventilation: a prospective observational study. Respir Res. 2018 Dec 7;19(1):245. PMID: 30526610

FLUID trial: a protocol for a hospital-wide open-label cluster crossover pragmatic comparative effectiveness randomised pilot trial.

First Author:

McIntyre L

Journal:

BMJ Open

Year:

2018

Group:

McIntyre L, Taljaard M, McArdle T, Fox-Robichaud A, English SW, Martin C, Marshall J, Menon K, Muscedere J, Cook DJ, Weijer C, Saginur R, Maybee A, Iyengar A, Forster A, Graham ID, Hawken S, McCartney C, Seely AJ, Stiell IG, Thavorn K, Fergusson DA. FLUID trial: a protocol for a hospital-wide open-label cluster crossover pragmatic comparative effectiveness randomised pilot trial. BMJ Open. 2018 Aug 23;8(8):e022780. PMID: 30139908

International Practice Variation in Weaning Critically Ill Adults from Invasive Mechanical Ventilation.

First Author:

Burns KEA

Journal:

Ann Am Thorac Soc.

Year:

2018

Group:

Burns KEA, Raptis S, Nisenbaum R, Rizvi L, Jones A, Bakshi J, Tan W, Meret A, Cook DJ, Lellouche F, Epstein SK, Gattas D, Kapadia FN, Villar J, Brochard L, Lessard MR, Meade MO. International Practice Variation in Weaning Critically Ill Adults from Invasive Mechanical Ventilation. Ann Am Thorac Soc. 2018 Apr;15(4):494-502. PMID: 29509509

Pooled analysis of higher versus lower blood pressure targets for vasopressor therapy septic and vasodilatory shock.

First Author:

Lamontagne F

Journal:

Intensive Care Med.

Year:

2018

Group:

Lamontagne F, Day AG, Meade MO, Cook DJ, Guyatt GH, Hylands M, Radermacher P, Chrétien JM, Beaudoin N, Hébert P, D'Aragon F, Meziani F, Asfar P. Pooled analysis of higher versus lower blood pressure targets for vasopressor therapy septic and vasodilatory shock. Intensive Care Med. 2018 Jan;44(1):12-21. PMID: 29260272

A Multicenter Study of Surrogate Decision-Makers Experiences in Being Approached for Consent for Patient Participation in Research.

First Author:

Burns KEA

Journal:

Ann Am Thorac Soc.

Year:

2017

Group:

,

Burns KEA, Juando Prats C, Maione M, Lanceta M, Zubrinich C Md, Jeffs L PhD, Smith OM; Canadian Critical Care Trials Group. A Multicenter Study of Surrogate Decision-Makers Experiences in Being Approached for Consent for Patient Participation in Research. Ann Am Thorac Soc. 2017 Feb;14(2):238-245. PMID: 27849142

Airway Management Strategies for Brain-injured Patients Meeting Standard Criteria to Consider Extubation. A Prospective Cohort Study.

First Author:

McCredie VA

Journal:

Ann Am Thorac Soc

Year:

2017

Group:

,

McCredie VA, Ferguson ND, Pinto RL, Adhikari NK, Fowler RA, Chapman MG, Burrell A, Baker AJ, Cook DJ, Meade MO, Scales DC; Canadian Critical Care Trials Group.Airway Management Strategies for Brain-injured Patients Meeting Standard Criteria to Consider Extubation. A Prospective Cohort Study. Ann Am Thorac Soc. 2017 Jan;14(1):85-93. PMID: 27870576

Improved Clinical Performance and Teamwork of Pediatric Interprofessional Resuscitation Teams With a Simulation-Based Educational Intervention.

First Author:

Gilfoyle E

Journal:

Pediatr Crit Care Med

Year:

2017

Group:

,

Gilfoyle E, Koot DA, Annear JC, Bhanji F, Cheng A, Duff JP, Grant VJ, St George-Hyslop CE, Delaloye NJ, Kotsakis A, McCoy CD, Ramsay CE, Weiss MJ, Gottesman RD; Teams4Kids Investigators and the Canadian Critical Care Trials Group. Improved Clinical Performance and Teamwork of Pediatric Interprofessional Resuscitation Teams With a Simulation-Based Educational Intervention. Pediatr Crit Care Med. 2017 Feb;18(2):e62-e69. PMID: 28157808

Time required to initiate outbreak and pandemic observational research.

First Author:

Rishu AH

Journal:

J Crit Care

Year:

2017

Group:

,

Rishu AH, Marinoff N, Julien L, Dumitrascu M, Marten N, Eggertson S, Willems S, Ruddell S, Lane D, Light B, Stelfox HT, Jouvet P, Hall R, Reynolds S, Daneman N, Fowler RA; Canadian Critical Care Trials Group. Time required to initiate outbreak and pandemic observational research. J Crit Care. 2017 Mar 1;40:7-10. PMID: 28288355

High-Quality Randomized Controlled Trials in Pediatric Critical Care: A Survey of Barriers and Facilitators.

First Author:

Duffett M

Journal:

Pediatr Crit Care Med.

Year:

2017

Group:

,

Duffett M, Choong K, Foster J, Meade M, Menon K, Parker M, Cook DJ; Canadian Critical Care Trials Group. High-Quality Randomized Controlled Trials in Pediatric Critical Care: A Survey of Barriers and Facilitators. Pediatr Crit Care Med. 2017 May;18(5):405-413. PMID: 28328786

A Randomized Controlled Trial of Corticosteroids in Pediatric Septic Shock: A Pilot Feasibility Study

First Author:

Menon K

Journal:

Pediatr Crit Care Med.

Year:

2017

Group:

,

Menon K, McNally D, O'Hearn K, Acharya A, Wong HR, Lawson M, Ramsay T, McIntyre L, Gilfoyle E, Tucci M, Wensley D, Gottesman R, Morrison G, Choong K; Canadian Critical Care Trials Group. A Randomized Controlled Trial of Corticosteroids in Pediatric Septic Shock: A Pilot Feasibility Study. Pediatr Crit Care Med. 2017 Jun;18(6):505-512. PMID: 28406862

Pediatric intensive care stress ulcer prevention (PIC-UP): a protocol for a pilot randomized trial.

First Author:

Duffett M

Journal:

Pilot Feasibility Stud

Year:

2017

Group:

,

Duffett M, Choong K, Foster J, Gilfoyle E, Lacroix J, Pai N, Thabane L, Cook DJ; Canadian Critical Care Trials Group. Pediatric intensive care stress ulcer prevention (PIC-UP): a protocol for a pilot randomized trial. Pilot Feasibility Stud. 2017 May 19;3:26. PMID: 28533916

Withholding Pantoprazole for Stress Ulcer Prophylaxis in Critically Ill Patients: A Pilot Randomized Clinical Trial and Meta-Analysis.

First Author:

Alhazzani W

Journal:

Crit Care Med.

Year:

2017

Group:

,

Alhazzani W, Guyatt G, Alshahrani M, Deane AM, Marshall JC, Hall R, Muscedere J, English SW, Lauzier F, Thabane L, Arabi YM, Karachi T, Rochwerg B, Finfer S, Daneman N, Alshamsi F, Zytaruk N, Heel-Ansdell D, Cook D; Canadian Critical Care Trials Group.Withholding Pantoprazole for Stress Ulcer Prophylaxis in Critically Ill Patients: A Pilot Randomized Clinical Trial and Meta-Analysis. Crit Care Med. 2017 Jul;45(7):1121-1129. PMID: 28459708

Prognostication in critically ill patients with severe traumatic brain injury: the TBI-Prognosis multicentre feasibility study.

First Author:

Turgeon AF

Journal:

BMJ Open.

Year:

2017

Group:

Turgeon AF, Lauzier F, Zarychanski R, Fergusson DA, Léger C, McIntyre LA, Bernard F, Rigamonti A, Burns K, Griesdale DE, Green R, Scales DC, Meade MO, Savard M, Shemilt M, Paquet J, Gariépy JL, Lavoie A, Reddy K, Jichici D, Pagliarello G, Zygun D, Moore L; TBI-Prognosis Study Team and the Canadian Critical Care Trials Group. Prognostication in critically ill patients with severe traumatic brain injury: the TBI-Prognosis multicentre feasibility study. BMJ Open. 2017 Apr 17;7(4):e013779. PMID: 28416497

Determinants of Antibiotic Tailoring in Pediatric Intensive Care: A National Survey.

First Author:

Fontela PS

Journal:

Pediatr Crit Care Med.

Year:

2017

Group:

,

Fontela PS, Quach C, Karim ME, Willson DF, Gilfoyle E, McNally JD, Gonzales M, Papenburg J, Reynolds S, Lacroix J; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network; on behalf of the Canadian Critical Care Trials Group. Determinants of Antibiotic Tailoring in Pediatric Intensive Care: A National Survey. Pediatr Crit Care Med. 2017 Sep;18(9):e395-e405. PMID: 28661973

Low brain tissue oxygenation contributes to the development of delirium in critically ill patients: A prospective observational study.

First Author:

Wood MD

Journal:

J Crit Care

Year:

2017

Group:

Wood MD, Maslove DM, Muscedere JG, Day AG, Gordon Boyd J. Cerebral Oxygenation and Neurological Outcomes Following Critical Illness (CONFOCAL) Research Group; Canadian Critical Care Trials Group. Low brain tissue oxygenation contributes to the development of delirium in critically ill patients: A prospective observational study. J Crit Care. 2017 Jun 15;41:289-295. PMID: 28668768

Errors During Resuscitation: The Impact of Perceived Authority on Delivery of Care.

First Author:

Delaloye NJ

Journal:

J Patient Saf.

Year:

2017

Group:

Delaloye NJ, Tobler K, O ľNeill T, Kotsakis A, Cooper J, Bank I, Gilfoyle E; Teams4Kids Investigators and the Canadian Critical Care Trials Group. Errors During Resuscitation: The Impact of Perceived Authority on Delivery of Care. J Patient Saf. 2017 Jun 30. doi: 10.1097/PTS.0000000000000359. [Epub ahead of print] PMID: 28671912

Incidence of delirium after cardiac surgery: protocol for the DELIRIUM-CS Canada cross-sectional cohort study.

First Author:

DELIRIUM-CS Investigators

Journal:

CMAJ Open

Year:

2017

Group:

DELIRIUM-CS Investigators*; Canadian Cardiovascular Critical Care Society Investigator Group and the Canadian Critical Care Trials Group. Incidence of delirium after cardiac surgery: protocol for the DELIRIUM-CS Canada cross-sectional cohort study. CMAJ Open. 2017 Jul 13;5(3):E565-E569. PMID: 28743102