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Screening and Prevention of Venous Thromboembolism in Critically Ill Patients: A Decision Analysis and Economic Evaluation

First Author:

Sud S

Journal:

Am J Respir Crit Care Med

Year:

2011

Group:

Sud S, Mittmann N, Cook DJ, Geerts W, Chan B, Dodek P, Gould MK, Guyatt G, Arabi Y, Fowler RA; On Behalf of the E-PROTECT Investigators and for the Canadian Critical Care Trials Group. Screening and Prevention of Venous Thromboembolism in Critically Ill Patients: A Decision Analysis and Economic Evaluation. Am J Respir Crit Care Med. 2011 Aug 25. [Epub ahead of print] PMID: 21868500

The age of blood evaluation (ABLE) randomized controlled trial: Study design

First Author:

Lacroix J

Journal:

Transfusion Medicine Reviews

Year:

2011

Group:

Lacroix J, Hébert PC, Fergusson D, Tinmouth A, Blajchman MA, Callum J, Cook D, Marshall J, McIntyre L, Turgeon A, for the ABLE study group, and for the Canadian Critical Care Trials Group. The age of blood evaluation (ABLE) randomized controlled trial: Study design. Transfusion Medicine Reviews 2011;25:197-205. PMID: 21550205

Functional disability 5 years after acute respiratory distress syndrome

First Author:

Herridge MS

Journal:

N Engl J Med

Year:

2011

Group:

Herridge MS, Tansey CM, Matté A, Tomlinson G, Diaz-Granados N, Cooper A, Guest CB, Mazer CD, Mehta S, Stewart TE, Kudlow P, Cook D, Slutsky AS, Cheung AM; for the Canadian Critical Care Trials Group. Functional disability 5 years after acute respiratory distress syndrome. N Engl J Med. 2011 Apr 7;364(14):1293-304. PMID: 21470008

A Canadian Critical Care Trials Group project in collaboration with the international forum for acute care trialists - Collaborative H1N1 Adjuvant Treatment pilot trial (CHAT): study protocol and design of a randomized controlled trial

First Author:

Burns KEA

Journal:

Trials

Year:

2011

Group:

Burns KEA, Chant C, Smith O, Cuthbertson B, Fowler R, Cook DJ, Kruger P, Webb S, Alhashemi J, Dominguez-Cherit G, Zala C, Rubenfeld GD, Marshall JC for the Canadian Critical Care Trials Group. A Canadian Critical Care Trials Group project in collaboration with the international forum for acute care trialists - Collaborative H1N1 Adjuvant Treatment pilot trial (CHAT): study protocol and design of a randomized controlled trial. Trials. 2011 Mar 9;12:70. PMID: 21388549

Persistent organ dysfunction plus death: a novel, composite outcome measure for critical care trials

First Author:

Heyland DK

Journal:

Crit Care

Year:

2011

Group:

Heyland DK, Muscedere J, Drover J, Jiang X, Day AG for the Canadian Critical Care Trials Group. Persistent organ dysfunction plus death: a novel, composite outcome measure for critical care trials. Crit Care. 2011;15(2):R98. Epub 2011 Mar 18. PMID: 21418560

Clinical practice guidelines for noninvasive positive pressure ventilation (NPPV) and noninvasive continuous positive airway pressure (nCPAP) in the acute care setting

First Author:

Keenan SP

Journal:

Can Med Assoc J

Year:

2011

Group:

Keenan SP, Sinuff T, Burns K, Muscedere J, Kutsogiannis J, Sangeeta M, Dodek P, Cook DJ, Ayas N, Adhikari N, Hand L, Scales D, Pagnotta R, Lazosky L, Rocker G, Dial S, Laupland K, Sanders K for the Canadian Critical Care Trials Group and Canadian Critical Care Society. Noninvasive Ventilation Guidelines Group. Clinical practice guidelines for noninvasive positive pressure ventilation (NPPV) and noninvasive continuous positive airway pressure (nCPAP) in the acute care setting. Can Med Assoc J 2011 Feb 22;183(3):E195-214. Epub 2011 Feb 14. PMID: 21324867

Recall of ICU stay in patients managed with a Sedation Protocol or a Sedation Protocol with Daily Sedative Interruption: A Pilot Study

First Author:

Ethier C

Journal:

J of Crit Care

Year:

2011

Group:

,

Ethier C, Burry L, Martinez-Motta C, Tirgari S, Jiang D, McDonald E, Granton J, Cook D, Mehta S, for the Canadian Critical Care Trials Group. Recall of ICU stay in patients managed with a Sedation Protocol or a Sedation Protocol with Daily Sedative Interruption: A Pilot Study. J of Crit Care 2011;26:127-132. Epub Oct 1, 2010. PMID: 20889289

Impact of Candida species on clinical outcomes in patients with suspected ventilator-associated pneumonia.

First Author:

Delisle MS

Journal:

Can Respir J

Year:

2011

Group:

Delisle MS, Williamson DR, Albert M, Perreault MM, Jiang X, Day AG, Heyland DK. Impact of Candida species on clinical outcomes in patients with suspected ventilator-associated pneumonia. Can Respir J. 2011;18(3):131-6. PMID: 21766075

The relationship between Candida species cultured from the respiratory tract and systemic inflammation in critically ill patients with ventilator-associated pneumonia.

First Author:

Williamson DR

Journal:

Can J Anaesth.

Year:

2011

Group:

Williamson DR, Albert M, Perreault MM, Delisle MS, Muscedere J, Rotstein C, Jiang X, Heyland DK. The relationship between Candida species cultured from the respiratory tract and systemic inflammation in critically ill patients with ventilator-associated pneumonia. Can J Anaesth. 2011;58(3):275-84. PMID: 2128730

Severe traumatic brain injury in children elevates glial fibrillary acidic protein in cerebrospinal fluid and serum

First Author:

Fraser DD

Journal:

Pediatr Crit Care Med

Year:

2011

Group:

Fraser DD, Close TE, Rose KL, Ward R, Mehl M, Farrell C, Lacroix J, Creery D, Kesselman M, Stanimirovic D, Hutchison JS, for the Canadian Critical Care Translational Biology Group. Severe traumatic brain injury in children elevates glial fibrillary acidic protein in cerebrospinal fluid and serum. Pediatr Crit Care Med 2011;12:319-24. PMID: 20625342

Potential pediatric intensive care unit demand/capacity mismatch due to novel pH1N1 in Canada.

First Author:

Stiff D

Journal:

Pediatr Crit Care Med

Year:

2011

Group:

Stiff D1, Kumar A, Kissoon N, Fowler R, Jouvet P, Skippen P, Smetanin P, Kesselman M, Veroukis S. Potential pediatric intensive care unit demand/capacity mismatch due to novel pH1N1 in Canada. Pediatr Crit Care Med. 2011 Mar;12(2):e51-7. PMID: 20473239

A comparison of early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury: a systematic review and meta-analysis.

First Author:

Karvellas CJ

Journal:

Crit Care

Year:

2011

Group:

Karvellas CJ, Farhat MR, Sajjad I, Mogensen SS, Leung AA, Wald R, Bagshaw SM. A comparison of early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury: a systematic review and meta-analysis. Crit Care. 2011;15(1):R72. PMID: 21352532

Antibiotic treatment duration for bloodstream infections in critically ill patients: a national survey of Canadian infectious diseases and critical care specialists.

First Author:

Daneman N

Journal:

Int J Antimicrob Agents

Year:

2011

Group:

Daneman N, Shore K, Pinto R, Fowler R.. Antibiotic treatment duration for bloodstream infections in critically ill patients: a national survey of Canadian infectious diseases and critical care specialists.Int J Antimicrob Agents. 2011 Dec;38(6):480-5. PMID: 21982833

Duration of antibiotic therapy for bacteremia: a systematic review and meta-analysis.

First Author:

Havey TC

Journal:

Crit Care

Year:

2011

Group:

Havey TC, Fowler RA, Daneman N.Duration of antibiotic therapy for bacteremia: a systematic review and meta-analysis. Crit Care. 2011;15(6):R267. PMID: 22085732

Association between length of storage of transfused red blood cells and multiple organ dysfunction syndrome in pediatric intensive care patients

First Author:

Gauvin F

Journal:

Transfusion

Year:

2010

Group:

,

Gauvin F, Spinella PC, Lacroix J, Choker G, Ducruet T, Karam O, Hébert PC, Hutchison JS, Hume HA, Tucci M, on behalf of the Canadian Critical Care Trials Group and the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.  Association between length of storage of transfused red blood cells and multiple organ dysfunction syndrome in pediatric intensive care patients. Transfusion. 2010 Sep;50(9):1902-13 PMID: 20456697

Red blood cell transfusion threshold in post-surgical pediatric intensive care patients: a randomized clinical trial

First Author:

Rouette J

Journal:

Annals of Surgery

Year:

2010

Group:

,

Rouette J, Trottier H, Ducruet T, Beaunoyer M, Lacroix J, Tucci M for the Canadian Critical Care Trials Group and PALISI.  Red blood cell transfusion threshold in post-surgical pediatric intensive care patients: a randomized clinical trial.  Annals of Surgery 2010; 251:421-7. PMID: 20118780

Comparison of two red-cell transfusion strategies after pediatric cardiac surgery: a subgroup analysis

First Author:

Willems A

Journal:

Crit Care Med

Year:

2010

Group:

,

Willems A, Harrington K, Lacroix J, Biarent D, Joffe ARI, Wensley D, Ducruet T, Hébert PC, Tucci M, on behalf of the TRIPICU investigators, for the Canadian Critical Care Trials Group and the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.  Comparison of two red-cell transfusion strategies after pediatric cardiac surgery: a subgroup analysis. Crit Care Med 2010;38(2):649-56. PMID: 19789443

Impact of hypotension and low cerebral perfusion pressure on outcomes in children treated with hypothermia therapy following severe traumatic brain injury: A post hoc analysis of the hypothermia pediatric head injury trial

First Author:

Hutchison JS

Journal:

Dev Neurosci

Year:

2010

Group:

,

Hutchison JS, Frndova H, Lo TY, Guerguerian AM for the Hypothermia Pediatric Head Injury Trial Investigators and for the Canadian Critical Care Trials Group. Impact of hypotension and low cerebral perfusion pressure on outcomes in children treated with hypothermia therapy following severe traumatic brain injury: A post hoc analysis of the hypothermia pediatric head injury trial. Dev Neurosci 2010;32:406-412. PMID: 21252486

Extracorporeal lung support for patients who had severe respiratory failure secondary to influenza A (H1N1) 2009 infection in Canada

First Author:

Freed DH

Journal:

Can J Anaesth

Year:

2010

Group:

,

Freed DH, Henzler D, White CW, Fowler R, Zarychanski R, Hutchison J, Arora RC, Manji RA, Legare JF, Drews T, Veroukis S, Kesselman M, Guerguerian AM, Kumar A; for the Canadian Critical Care Trials Group. Extracorporeal lung support for patients who had severe respiratory failure secondary to influenza A (H1N1) 2009 infection in Canada. Can J Anaesth 2010;57(3):240-7. PMID: 20082167

Critical illness in children with influenza A/pH1N1 2009 infection in Canada

First Author:

Jouvet P

Journal:

Pediatr Crit Care Med

Year:

2010

Group:

,

Jouvet P, Hutchison J, Pinto R, Menon K, Rodin R, Choong K, Kesselman M, Veroukis S, André Dugas M, Santschi M, Guerguerian AM, Withington D, Alsaati B, Joffe AR, Drews T, Skippen P, Rolland E, Kumar A, Fowler RA, for the Canadian Critical Care Trials Group H1N1 Collaborative. Critical illness in children with influenza A/pH1N1 2009 infection in Canada. Pediatr Crit Care Med. 2010 Sep;11(5):603-9. PMID: 20308929

The 4Ts scoring system for heparin induced thrombocytopenia in medical-surgical ICU patients

First Author:

Crowther MA

Journal:

J Crit Care

Year:

2010

Group:

,

Crowther MA, Cook DJ, Albert M, Williamson D, Meade M, Granton J, Skrobik Y, Langevin S, Mehta S, Hebert PC, Guyatt GH, Geerts W, Rabbat C, Douketis J, Zytaruk N, Sheppard J, Greinacher A, Warkentin TE for the Canadian Critical Care Trials Group. The 4Ts scoring system for heparin induced thrombocytopenia in medical-surgical ICU patients. J Crit Care 2010; 25(2):287-293. doi:10.1016/j.jcrc.2009.12.006 PMID: 20149589

Elevated plasma matrix metalloproteinases and their tissue inhibitors in patients with severe sepsis

First Author:

Yazdan-Ashoori P

Journal:

Journal of Critical Care

Year:

2010

Group:

Yazdan-Ashoori P, Liaw P, Toltl L, Webb B, Kilmer G, Carter D, Fraser DD (2011) Elevated plasma matrix metalloproteinases and their tissue inhibitors in patients with severe sepsis. Journal of Critical Care. Mar 23.

A prospective multicenter study of adrenal function in critically ill children.

First Author:

Menon K

Journal:

Am J Respir Crit Care Med.

Year:

2010

Group:

,

Menon K, Ward RE, Lawson ML, Gaboury I, Hutchison JS, Hébert PC; Canadian Critical Care Trials Group. A prospective multicenter study of adrenal function in critically ill children. Am J Respir Crit Care Med. 2010 Jul 15;182(2):246-51. PMID: 20299532

Vasopressin in Pediatric Vasodilatory Shock - A Multi-center Randomized Controlled Trial

First Author:

Choong K

Journal:

Am J Respir Crit Care Med

Year:

2009

Group:

,

Choong K, Bohn D, Fraser DD, Gaboury I, Hutchison JS, Joffe AR, Litalien C, Menon K, McNamara P, Ward RB with the Canadian Critical Care Trials Group. Vasopressin in Pediatric Vasodilatory Shock - A Multi-center Randomized Controlled Trial. Am J Respir Crit Care Med 2009;180(7)632-9. PMID: 19608718