Publications

Menon K, O'Hearn K, McNally JD, Acharya A, Wong HR, Lawson M, Ramsay T, McIntyre L, Gilfoyle E, Tucci M, Wensley D, Gottesman R, Morrison G, Choong K. Comparison of Consent Models in a Randomized Trial of Corticosteroids in Pediatric Septic Shock. Pediatr Crit Care Med. 2017 Nov;18(11):1009-1018. PMID: 28817507.

Canadian Guidelines for the Use of Targeted Temperature Management (Therapeutic Hypothermia) After Cardiac Arrest: A joint statement from The Canadian Association of Emergency Physicians (CAEP), the Canadian Critical Care Society (CCCS), Canadian Neurocritical Care Society (CNCCS), and the Canadian Critical Care Trials Group (CCCTG)

First Author:

Howes D

Journal:

Resuscitation

Year:

2016

Group:

Howes D, Gray SH, Brooks SC, Boyd JG, Djogovic D, Golan E, Green RS, Jacka MJ, Sinuff T, Chaplin T, Smith OM, Owen J, Szulewski A, Murphy L, Irvine S, Jichici D, Muscedere J. Canadian Guidelines for the Use of Targeted Temperature Management (Therapeutic Hypothermia) After Cardiac Arrest: A joint statement from The Canadian Association of Emergency Physicians (CAEP), the Canadian Critical Care Society (CCCS), Canadian Neurocritical Care Society (CNCCS), and the Canadian Critical Care Trials Group (CCCTG). Resuscitation. 2016 Jan;98:48-63. PMID: 26417702

Duration of Antimicrobial Treatment for Bacteremia in Canadian Critically Ill Patients.

First Author:

Daneman N

Journal:

Crit Care Med.

Year:

2016

Group:

Daneman N, Rishu AH, Xiong W, Bagshaw SM, Dodek P, Hall R, Kumar A, Lamontagne F, Lauzier F, Marshall J, Martin CM, McIntyre L, Muscedere J, Reynolds S, Stelfox HT, Cook DJ, Fowler RA; Canadian Critical Care Trials Group. Duration of Antimicrobial Treatment for Bacteremia in Canadian Critically Ill Patients. Crit Care Med.2016 Feb;44(2):256-64. PMID: 26496448

Determination of death after circulatory arrest by intensive care physicians: A survey of current practice in the Netherlands.

First Author:

Wind J

Journal:

J Crit Care

Year:

2016

Group:

Wind J, van Mook WN, Dhanani S, van Heurn EW.Determination of death after circulatory arrest by intensive care physicians: A survey of current practice in the Netherlands. J Crit Care. 2016 Feb;31(1):2-6. PMID: 26431638

Enriched Administrative Data Can Be Used To Retrospectively Identify All Known Cases of Primary Subarachnoid Hemorrhage.

First Author:

English SW

Journal:

J Clin Epidemiol.

Year:

2016

Group:

English SW, McIntyre L, Fergusson D, Turgeon A, Sun C, Dos Santos MP, Lum C, Sinclair J, Forster A, van Walraven C. Enriched Administrative Data Can Be Used To Retrospectively Identify All Known Cases of Primary Subarachnoid Hemorrhage. J Clin Epidemiol. 2016 Feb;70:146-54. PMID: 26399902

Enhanced Protein-Energy Provision via the Enteral Route in Critically Ill Patients (PEP uP Protocol): A Review of Evidence.

First Author:

Lee ZY

Journal:

Nutr Clin Pract.

Year:

2016

Group:

Lee ZY, Barakatun-Nisak MY, Airini IN, Heyland DK. Enhanced Protein-Energy Provision via the Enteral Route in Critically Ill Patients (PEP uP Protocol): A Review of Evidence.Nutr Clin Pract. 2016 Feb;31(1):68-79. PMID: 26385874

Nurse Research Experiences and Attitudes Toward the Conduct of Intensive Care Research: A Questionnaire Study

First Author:

Smith OM

Journal:

Crit Care Med.

Year:

2016

Group:

Smith, OM, Dale, C, Mehta, S, Pinto, R, Rose, LN. Nurse Research Experiences and Attitudes Toward the Conduct of Intensive Care Research: A Questionnaire Study. Crit Care Med. 2016 Jan;44(1):153-61. PMID: 26672924

Determinants of Citation Impact in Large Clinical Trials in Critical Care: The Role of Investigator-led Clinical Trials Groups.

First Author:

Marshall JC

Journal:

Crit Care Med.

Year:

2016

Group:

Marshall JC, Kwong W, Kommaraju K, Burns KE. Determinants of Citation Impact in Large Clinical Trials in Critical Care: The Role of Investigator-Led Clinical Trials Groups. Crit Care Med. 2016 Apr;44(4):663-70. PMID: 26571189

Red Blood Cell Transfusion in Patients With Traumatic Brain Injury: A Systematic Review and Meta-Analysis.

First Author:

Boutin A

Journal:

Transfus Med Rev

Year:

2016

Group:

Boutin A, Chassé M, Shemilt M, Lauzier F, Moore L, Zarychanski R, Griesdale D, Desjardins P, Lacroix J, Fergusson D, Turgeon AF. Red Blood Cell Transfusion in Patients With Traumatic Brain Injury: A Systematic Review and Meta-Analysis. Transfus Med Rev. 2016 Jan;30(1):15-24. PMID: 26409622

Higher versus lower blood pressure targets for vasopressor therapy in shock: a multicentre pilot randomized controlled trial.

First Author:

Lamontagne F

Journal:

Intensive Care Med

Year:

2016

Group:

CCCTG, CCCPEDS

Lamontagne F, Meade MO, Hébert PC, Asfar P, Lauzier F, Seely AJ, Day AG, Mehta S, Muscedere J, Bagshaw SM, Ferguson ND, Cook DJ, Kanji S, Turgeon AF, Herridge MS, Subramanian S, Lacroix J, Adhikari NK, Scales DC, Fox-Robichaud A, Skrobik Y, Whitlock RP, Green RS, Koo KK, Tanguay T, Magder S, Heyland DK; Canadian Critical Care Trials Group. Higher versus lower blood pressure targets for vasopressor therapy in shock: a multicentre pilot randomized controlled trial. Intensive Care Med. 2016 Feb 18. [Epub ahead of print] PMID: 26891677

Stress ulcer prophylaxis in critical illness: a Canadian survey.

First Author:

Shears M

Journal:

Can J Anaesth.

Year:

2016

Group:

Shears M, Alhazzani W, Marshall JC, Muscedere J, Hall R, English SW, Dodek PM, Lauzier F, Kanji S, Duffett M, Barletta J, Alshahrani M, Arabi Y, Deane A, Cook DJ. Stress ulcer prophylaxis in critical illness: a Canadian survey. Can J Anaesth. 2016 Feb 24. [Epub ahead of print] PMID: 26911559

The influence of corticosteroid treatment on the outcome of influenza A(H1N1pdm09)-related critical illness

First Author:

Delaney JW

Journal:

Crit Care

Year:

2016

Group:

Delaney JW, Pinto R, Long J, Lamontagne F, Adhikari NK, Kumar A, Marshall JC, Cook DJ, Jouvet P, Ferguson ND, Griesdale D, Burry LD, Burns KE, Hutchison J, Mehta S, Menon K, Fowler RA; Canadian Critical Care Trials Group H1N1 Collaborative. The influence of corticosteroid treatment on the outcome of influenza A(H1N1pdm09)-related critical illness. Crit Care. 2016 Mar 30;20(1):75. PMID: 27036638

CYCLE pilot: a protocol for a pilot randomised study of early cycle ergometry versus routine physiotherapy in mechanically ventilated patients

First Author:

Kho ME

Journal:

BMJ Open

Year:

2016

Group:

Kho, ME, Molloy,AJ, Clarke, F, Herridge, MS, Koo, KKY, Rudkowski, J, Seely, AJE, Pellizzari, JR, Tarride, JE, Mourtzakis, M, Karachi, T, Cook, DJ, the Canadian Critical Care Trials Group. CYCLE pilot: a protocol for a pilot randomised study of early cycle ergometry versus routine physiotherapy in mechanically ventilated patients. BMJ Open. 2016 Apr 8;6(4):e011659. PMID: 27059469

Predicting Performance Status 1 Year After Critical Illness in Patients 80 Years or Older: Development of a Multivariable Clinical Prediction Model.

First Author:

Heyland DK

Journal:

Crit Care Med

Year:

2016

Group:

Heyland DK, Stelfox HT, Garland A, Cook D, Dodek P, Kutsogiannis J, Jiang X, Turgeon AF, Day AG; Canadian Critical Care Trials Group and the Canadian Researchers at the End of Life Network. Predicting Performance Status 1 Year After Critical Illness in Patients 80 Years or Older: Development of a Multivariable Clinical Prediction Model. Crit Care Med. 2016 Sep;44(9):1718-26. PMID: 27075141

Recovery and outcomes after the acute respiratory distress syndrome (ARDS) in patients and their family caregivers.

First Author:

Herridge MS

Journal:

Intensive Care Med.

Year:

2016

Group:

Herridge MS, Moss M, Hough CL, Hopkins RO, Rice TW, Bienvenu OJ, Azoulay E.Recovery and outcomes after the acute respiratory distress syndrome (ARDS) in patients and their family caregivers. Intensive Care Med. 2016 May;42(5):725-38. PMID: 27025938

Steroids in fluid and/or vasoactive infusion dependent pediatric shock: study protocol for a randomized controlled trial.

First Author:

O'Hearn K

Journal:

Trials

Year:

2016

Group:

O'Hearn K, McNally D, Choong K, Acharya A, Wong HR, Lawson M, Ramsay T, McIntyre L, Gilfoyle E, Tucci M, Wensley D, Gottesman R, Morrison G, Menon K; Canadian Critical Care Trials Group. Steroids in fluid and/or vasoactive infusion dependent pediatric shock: study protocol for a randomized controlled trial. Trials. 2016 May 6;17(1):238. PMID: 27153945

One-Year Outcomes in Caregivers of Critically Ill Patients

First Author:

Cameron JI

Journal:

N Engl J Med

Year:

2016

Group:

Cameron JI, Chu LM, Matte A, Tomlinson G, Chan L, Thomas C, Friedrich JO, Mehta S, Lamontagne F, Levasseur M, Ferguson ND, Adhikari NK, Rudkowski JC, Meggison H, Skrobik Y, Flannery J, Bayley M, Batt J, dos Santos C, Abbey SE, Tan A, Lo V, Mathur S, Parotto M, Morris D, Flockhart L, Fan E, Lee CM, Wilcox ME, Ayas N, Choong K, Fowler R, Scales DC, Sinuff T, Cuthbertson BH, Rose L, Robles P, Burns S, Cypel M, Singer L, Chaparro C, Chow CW, Keshavjee S, Brochard L, Hébert P, Slutsky AS, Marshall JC, Cook D, Herridge MS; RECOVER Program Investigators (Phase 1: towards RECOVER); Canadian Critical Care Trials Group. One-Year Outcomes in Caregivers of Critically Ill Patients. N Engl J Med. 2016 May 12;374(19):1831-41. PMID: 27168433

Serum Biomarkers Help Predict Attention Problems in Critically Ill Children With Traumatic Brain Injury.

First Author:

Wilkinson AA

Journal:

Pediatr Crit Care Med.

Year:

2016

Group:

CCCTG, CCCTBG

Wilkinson AA, Simic N, Frndova H, Taylor MJ, Choong K, Fraser D, Campbell C, Dhanani S, Kuehn S, Beauchamp MH, Farrell C, Anderson V, Guerguerian AM, Dennis M, Schachar R, Hutchison JS; Attention and Traumatic Brain Injury Investigators, the Canadian Critical Care Trials Group, and the Canadian Critical Care Translational Biology Group. Serum Biomarkers Help Predict Attention Problems in Critically Ill Children With Traumatic Brain Injury. Pediatr Crit Care Med. 2016 Jul;17(7):638-48. PMID: 27167007

Multicountry survey of emergency and critical care medicine physicians' fluid resuscitation practices for adult patients with early septic shock.

First Author:

McIntyre L

Journal:

BMJ Open

Year:

2016

Group:

McIntyre L, Rowe BH, Walsh TS, Gray A, Arabi Y, Perner A, Gordon A, Marshall J, Cook D, Fox-Robichaud A, Bagshaw SM, Green R, Schweitzer I, Turgeon A, Zarychanski R, English S, Chassé M, Stiell I, Fergusson D; Canadian Critical Care Trials Group. Multicountry survey of emergency and critical care medicine physicians' fluid resuscitation practices for adult patients with early septic shock. BMJ Open. 2016 Jul 7;6(7). PMID: 27388345

Risk factors for mortality in patients admitted to intensive care units with pneumonia.

First Author:

Li G

Journal:

Respir Res.

Year:

2016

Group:

Li G, Cook DJ, Thabane L, Friedrich JO, Crozier TM, Muscedere J, Granton J, Mehta S, Reynolds SC, Lopes RD, Francois L, Freitag AP, Levine MA; PROTECT Investigators for the Canadian Critical Care Trials Group, and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Risk factors for mortality in patients admitted to intensive care units with pneumonia. Respir Res. 2016 Jul 11;17(1):80. PMID: 27401184

Survey of Sedation and Analgesia Practice Among Canadian Pediatric Critical Care Physicians

First Author:

Garcia Guerra G

Journal:

Pediatr Crit Care Med.

Year:

2016

Group:

Guerra GG, Joffe AR, Cave D, Duff J, Duncan S, Sheppard C, Tawfik G, Hartling L, Jou H, Vohra S; Sedation Withdrawal and Analgesia Team, and the Canadian Critical Care Trials Group. Survey of Sedation and Analgesia Practice Among Canadian Pediatric Critical Care Physicians. Pediatr Crit Care Med. 2016 Sep;17(9):823-30. PMID: 27467012

Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial-PROSPECT: a pilot trial.

First Author:

Cook DJ

Journal:

Trials

Year:

2016

Group:

Cook DJ, Johnstone J, Marshall JC, Lauzier F, Thabane L, Mehta S, Dodek PM, McIntyre L, Pagliarello J, Henderson W, Taylor RW, Cartin-Ceba R, Golan E, Herridge M, Wood G, Ovakim D, Karachi T, Surette MG, Bowdish DM, Lamarche D, Verschoor CP, Duan EH, Heels-Ansdell D, Arabi Y, Meade M; PROSPECT Investigators and the Canadian Critical Care Trials Group. Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial-PROSPECT: a pilot trial. Trials. 2016 Aug 2;17:377. PMID: 27480757

Variation in diurnal sedation in mechanically ventilated patients who are managed with a sedation protocol alone or a sedation protocol and daily interruption.

First Author:

Mehta S

Journal:

Crit Care

Year:

2016

Group: