Publications

Lamontagne F, Day AG, Meade MO, Cook DJ, Guyatt GH, Hylands M, Radermacher P, Chrétien JM, Beaudoin N, Hébert P, D'Aragon F, Meziani F, Asfar P. Pooled analysis of higher versus lower blood pressure targets for vasopressor therapy septic and vasodilatory shock. Intensive Care Med. 2018 Jan;44(1):12-21. PMID: 29260272

A Multicenter Study of Surrogate Decision-Makers Experiences in Being Approached for Consent for Patient Participation in Research.

First Author:

Burns KEA

Journal:

Ann Am Thorac Soc.

Year:

2017

Group:

Burns KEA, Juando Prats C, Maione M, Lanceta M, Zubrinich C Md, Jeffs L PhD, Smith OM; Canadian Critical Care Trials Group. A Multicenter Study of Surrogate Decision-Makers Experiences in Being Approached for Consent for Patient Participation in Research. Ann Am Thorac Soc. 2017 Feb;14(2):238-245. PMID: 27849142

Airway Management Strategies for Brain-injured Patients Meeting Standard Criteria to Consider Extubation. A Prospective Cohort Study.

First Author:

McCredie VA

Journal:

Ann Am Thorac Soc

Year:

2017

Group:

McCredie VA, Ferguson ND, Pinto RL, Adhikari NK, Fowler RA, Chapman MG, Burrell A, Baker AJ, Cook DJ, Meade MO, Scales DC; Canadian Critical Care Trials Group.Airway Management Strategies for Brain-injured Patients Meeting Standard Criteria to Consider Extubation. A Prospective Cohort Study. Ann Am Thorac Soc. 2017 Jan;14(1):85-93. PMID: 27870576

Improved Clinical Performance and Teamwork of Pediatric Interprofessional Resuscitation Teams With a Simulation-Based Educational Intervention.

First Author:

Gilfoyle E

Journal:

Pediatr Crit Care Med

Year:

2017

Group:

Gilfoyle E, Koot DA, Annear JC, Bhanji F, Cheng A, Duff JP, Grant VJ, St George-Hyslop CE, Delaloye NJ, Kotsakis A, McCoy CD, Ramsay CE, Weiss MJ, Gottesman RD; Teams4Kids Investigators and the Canadian Critical Care Trials Group. Improved Clinical Performance and Teamwork of Pediatric Interprofessional Resuscitation Teams With a Simulation-Based Educational Intervention. Pediatr Crit Care Med. 2017 Feb;18(2):e62-e69. PMID: 28157808

Time required to initiate outbreak and pandemic observational research.

First Author:

Rishu AH

Journal:

J Crit Care

Year:

2017

Group:

Rishu AH, Marinoff N, Julien L, Dumitrascu M, Marten N, Eggertson S, Willems S, Ruddell S, Lane D, Light B, Stelfox HT, Jouvet P, Hall R, Reynolds S, Daneman N, Fowler RA; Canadian Critical Care Trials Group. Time required to initiate outbreak and pandemic observational research. J Crit Care. 2017 Mar 1;40:7-10. PMID: 28288355

High-Quality Randomized Controlled Trials in Pediatric Critical Care: A Survey of Barriers and Facilitators.

First Author:

Duffett M

Journal:

Pediatr Crit Care Med.

Year:

2017

Group:

Duffett M, Choong K, Foster J, Meade M, Menon K, Parker M, Cook DJ; Canadian Critical Care Trials Group. High-Quality Randomized Controlled Trials in Pediatric Critical Care: A Survey of Barriers and Facilitators. Pediatr Crit Care Med. 2017 May;18(5):405-413. PMID: 28328786

A Randomized Controlled Trial of Corticosteroids in Pediatric Septic Shock: A Pilot Feasibility Study

First Author:

Menon K

Journal:

Pediatr Crit Care Med.

Year:

2017

Group:

Menon K, McNally D, O'Hearn K, Acharya A, Wong HR, Lawson M, Ramsay T, McIntyre L, Gilfoyle E, Tucci M, Wensley D, Gottesman R, Morrison G, Choong K; Canadian Critical Care Trials Group. A Randomized Controlled Trial of Corticosteroids in Pediatric Septic Shock: A Pilot Feasibility Study. Pediatr Crit Care Med. 2017 Jun;18(6):505-512. PMID: 28406862

Pediatric intensive care stress ulcer prevention (PIC-UP): a protocol for a pilot randomized trial.

First Author:

Duffett M

Journal:

Pilot Feasibility Stud

Year:

2017

Group:

Duffett M, Choong K, Foster J, Gilfoyle E, Lacroix J, Pai N, Thabane L, Cook DJ; Canadian Critical Care Trials Group. Pediatric intensive care stress ulcer prevention (PIC-UP): a protocol for a pilot randomized trial. Pilot Feasibility Stud. 2017 May 19;3:26. PMID: 28533916

Withholding Pantoprazole for Stress Ulcer Prophylaxis in Critically Ill Patients: A Pilot Randomized Clinical Trial and Meta-Analysis.

First Author:

Alhazzani W

Journal:

Crit Care Med.

Year:

2017

Group:

Alhazzani W, Guyatt G, Alshahrani M, Deane AM, Marshall JC, Hall R, Muscedere J, English SW, Lauzier F, Thabane L, Arabi YM, Karachi T, Rochwerg B, Finfer S, Daneman N, Alshamsi F, Zytaruk N, Heel-Ansdell D, Cook D; Canadian Critical Care Trials Group.Withholding Pantoprazole for Stress Ulcer Prophylaxis in Critically Ill Patients: A Pilot Randomized Clinical Trial and Meta-Analysis. Crit Care Med. 2017 Jul;45(7):1121-1129. PMID: 28459708

Prognostication in critically ill patients with severe traumatic brain injury: the TBI-Prognosis multicentre feasibility study.

First Author:

Turgeon AF

Journal:

BMJ Open.

Year:

2017

Group:

Turgeon AF, Lauzier F, Zarychanski R, Fergusson DA, Léger C, McIntyre LA, Bernard F, Rigamonti A, Burns K, Griesdale DE, Green R, Scales DC, Meade MO, Savard M, Shemilt M, Paquet J, Gariépy JL, Lavoie A, Reddy K, Jichici D, Pagliarello G, Zygun D, Moore L; TBI-Prognosis Study Team and the Canadian Critical Care Trials Group. Prognostication in critically ill patients with severe traumatic brain injury: the TBI-Prognosis multicentre feasibility study. BMJ Open. 2017 Apr 17;7(4):e013779. PMID: 28416497

Determinants of Antibiotic Tailoring in Pediatric Intensive Care: A National Survey.

First Author:

Fontela PS

Journal:

Pediatr Crit Care Med.

Year:

2017

Group:

Fontela PS, Quach C, Karim ME, Willson DF, Gilfoyle E, McNally JD, Gonzales M, Papenburg J, Reynolds S, Lacroix J; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network; on behalf of the Canadian Critical Care Trials Group. Determinants of Antibiotic Tailoring in Pediatric Intensive Care: A National Survey. Pediatr Crit Care Med. 2017 Sep;18(9):e395-e405. PMID: 28661973

Low brain tissue oxygenation contributes to the development of delirium in critically ill patients: A prospective observational study.

First Author:

Wood MD

Journal:

J Crit Care

Year:

2017

Group:

Wood MD, Maslove DM, Muscedere JG, Day AG, Gordon Boyd J. Cerebral Oxygenation and Neurological Outcomes Following Critical Illness (CONFOCAL) Research Group; Canadian Critical Care Trials Group. Low brain tissue oxygenation contributes to the development of delirium in critically ill patients: A prospective observational study. J Crit Care. 2017 Jun 15;41:289-295. PMID: 28668768

Errors During Resuscitation: The Impact of Perceived Authority on Delivery of Care.

First Author:

Delaloye NJ

Journal:

J Patient Saf.

Year:

2017

Group:

Delaloye NJ, Tobler K, OʼNeill T, Kotsakis A, Cooper J, Bank I, Gilfoyle E; Teams4Kids Investigators and the Canadian Critical Care Trials Group. Errors During Resuscitation: The Impact of Perceived Authority on Delivery of Care. J Patient Saf. 2017 Jun 30. doi: 10.1097/PTS.0000000000000359. [Epub ahead of print] PMID: 28671912

Incidence of delirium after cardiac surgery: protocol for the DELIRIUM-CS Canada cross-sectional cohort study.

First Author:

DELIRIUM-CS Investigators

Journal:

CMAJ Open

Year:

2017

Group:

DELIRIUM-CS Investigators*; Canadian Cardiovascular Critical Care Society Investigator Group and the Canadian Critical Care Trials Group. Incidence of delirium after cardiac surgery: protocol for the DELIRIUM-CS Canada cross-sectional cohort study. CMAJ Open. 2017 Jul 13;5(3):E565-E569. PMID: 28743102

Fluids in Sepsis and Septic Shock (FISSH): protocol for a pilot randomised controlled trial.

First Author:

Rochwerg B

Journal:

BMJ Open

Year:

2017

Group:

Rochwerg B, Millen T, Austin P, Zeller M, D'Aragon F, Jaeschke R, Masse MH, Mehta S, Lamontagne F, Meade M, Guyatt G, Cook DJ; Canadian Critical Care Trials Group. Fluids in Sepsis and Septic Shock (FISSH): protocol for a pilot randomised controlled trial. BMJ Open. 2017 Jul 20;7(7):e017602. PMID: 28729329

Brain biomarkers and pre-injury cognition are associated with long-term cognitive outcome in children with traumatic brain injury.

First Author:

Wilkinson AA

Journal:

BMC Pediatr

Year:

2017

Group:

CCCTG, CCCTBG, CCCPEDS

Wilkinson AA, Dennis M, Simic N, Taylor MJ, Morgan BR, Frndova H, Choong K, Campbell C, Fraser D, Anderson V, Guerguerian AM, Schachar R, Hutchison J; Canadian Critical Care Trials Group (CCCTG); Canadian Critical Care Translational Biology Group (CCCTBG). Brain biomarkers and pre-injury cognition are associated with long-term cognitive outcome in children with traumatic brain injury. BMC Pediatr. 2017 Jul 24;17(1):173. PMID: 28738850

Safety and Feasibility of a Protocolized Approach to In-Bed Cycling Exercise in the Intensive Care Unit: Quality Improvement Project.

First Author:

Kimawi I

Journal:

Phys Ther

Year:

2017

Group:

Kimawi I, Lamberjack B, Nelliot A, Toonstra AL, Zanni J, Huang M, Mantheiy E, Kho ME, Needham DM.Safety and Feasibility of a Protocolized Approach to In-Bed Cycling Exercise in the Intensive Care Unit: Quality Improvement Project. Phys Ther. 2017 Jun 1;97(6):593-602. PMID: 28379571

Early Exercise in Critically Ill Youth and Children, a Preliminary Evaluation: The wEECYCLE Pilot Trial.

First Author:

Choong K

Journal:

Pediatr Crit Care Med

Year:

2017

Group:

Choong K, Awladthani S, Khawaji A, Clark H, Borhan A, Cheng J, Laskey S, Neu C, Sarti A, Thabane L, Timmons BW, Zheng K, Al-Harbi S; Canadian Critical Care Trials Group. Early Exercise in Critically Ill Youth and Children, a Preliminary Evaluation: The wEECYCLE Pilot Trial. Pediatr Crit Care Med. 2017 Nov;18(11):e546-e554. PMID: 28922268

Canada-DONATE study protocol: a prospective national observational study of the medical management of deceased organ donors.

First Author:

D'Aragon F

Journal:

BMJ Open

Year:

2017

Group:

D'Aragon F, Dhanani S, Lamontagne F, Cook DJ, Burns K, Akhtar A, Chassé M, Frenette AJ, Keenan S, Lize JF, Kutsogiannis DJ, Kramer A, Hand LE, Arseneau E, Masse MH, Ribic C, Ball I, Baker A, Boyd G, Rochwerg B, Healey A, Hanna S, Guyatt GH, Meade MO; Canadian Critical Care Trials Group and the Canadian National Transplant Research Program. Canada-DONATE study protocol: a prospective national observational study of the medical management of deceased organ donors. BMJ Open. 2017 Sep 28;7(9). PMID: 28963316

Performance Monitoring in Children Following Traumatic Brain Injury Compared to Typically Developing Children.

First Author:

Wilkinson AA

Journal:

Child Neurol Open.

Year:

2017

Group:

Wilkinson AA, Dennis M, Taylor MJ, Guerguerian AM, Boutis K, Choong K, Campbell C, Fraser D, Hutchison J, Schachar R; Canadian Critical Care Trials Group (CCCTG). Performance Monitoring in Children Following Traumatic Brain Injury Compared to Typically Developing Children. Child Neurol Open. 2017 Oct 12;4. eCollection 2017 Jan-Dec. PMID: 29051909

2009-2010 Influenza A(H1N1)-related critical illness among Aboriginal and non-Aboriginal Canadians.

First Author:

Jung JJ

Journal:

PLoS One.

Year:

2017

Group:

CCCTG, CCCRCG, CCCPEDS

Jung JJ, Pinto R, Zarychanski R, Cook DJ, Jouvet P, Marshall JC, Kumar A, Long J, Rodin R, Fowler RA; Canadian Critical Care Trials Group H1N1 Collaborative. 2009-2010 Influenza A(H1N1)-related critical illness among Aboriginal and non-Aboriginal Canadians. PLoS One. 2017 Oct 19;12(10):e0184013. eCollection 2017. PMID: 29049285

Vasopressor Use for Severe Hypotension-A Multicentre Prospective Observational Study.

First Author:

Lamontagne F

Journal:

PLoS One

Year:

2017

Group:

Lamontagne F, Cook DJ, Meade MO, Seely A, Day AG, Charbonney E, Serri K, Skrobik Y, Hebert P, St-Arnaud C, Quiroz-Martinez H, Mayette M, Heyland DK. Vasopressor Use for Severe Hypotension-A Multicentre Prospective Observational Study. PLoS One. 2017 Jan 20;12(1):e0167840. PMID: 28107357

Study protocol for a phase II dose evaluation randomized controlled trial of cholecalciferol in critically ill children with vitamin D deficiency (VITdAL-PICU study).

First Author:

McNally D

Journal:

Pilot Feasibility Stud

Year:

2017

Group:

CCCTG, CCCRCG, CCCPEDS

McNally D, Amrein K, O'Hearn K, Fergusson D, Geier P, Henderson M, Khamessan A, Lawson ML, McIntyre L, Redpath S, Weiler HA, Menon K; Canadian Critical Care Trials Group.. Study protocol for a phase II dose evaluation randomized controlled trial of cholecalciferol in critically ill children with vitamin D deficiency (VITdAL-PICU study). Pilot Feasibility Stud. 2017 Dec 8;3:70. PMID: 29234503

Management of Acute Respiratory Distress Syndrome and Refractory Hypoxemia. A Multicenter Observational Study.

First Author:

Duan EH

Journal:

Ann Am Thorac Soc.

Year:

2017

Group: