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Variation in diurnal sedation in mechanically ventilated patients who are managed with a sedation protocol alone or a sedation protocol and daily interruption.

First Author:

Mehta S

Journal:

Crit Care

Year:

2016

Group:

,

Mehta S, Meade M, Burry L, Mallick R, Katsios C, Fergusson D, Dodek P, Burns K, Herridge M, Devlin JW, Tanios M, Fowler R, Jacka M, Skrobik Y, Olafson K, Cook D; SLEAP Investigators and the Canadian Critical Care Trials Group. Variation in diurnal sedation in mechanically ventilated patients who are managed with a sedation protocol alone or a sedation protocol and daily interruption. Crit Care. 2016 Aug 1;20(1):233. PMID: 27480314

The Development of a Critical Care Resident Research Curriculum: A Needs Assessment.

First Author:

Jain S

Journal:

Can Respir J.

Year:

2016

Group:

,

Jain S, Menon K, Piquette D, Gottesman R, Hutchison J, Gilfoyle E, Group CC. The Development of a Critical Care Resident Research Curriculum: A Needs Assessment. Can Respir J. 2016; Epub 2016 Aug 16. PMID: 27610029

A trial to determine whether septic shock-reversal is quicker in pediatric patients randomized to an early goal-directed fluid-sparing strategy versus usual care (SQUEEZE): study protocol for a pilot randomized controlled trial.

First Author:

Parker MJ

Journal:

Trials

Year:

2016

Group:

, ,

Parker MJ, Thabane L, Fox-Robichaud A, Liaw P, Choong K; Canadian Critical Care Trials Group and the Canadian Critical Care Translational Biology Group.A trial to determine whether septic shock-reversal is quicker in pediatric patients randomized to an early goal-directed fluid-sparing strategy versus usual care (SQUEEZE): study protocol for a pilot randomized controlled trial. Trials. 2016 Nov 22;17(1):556. PMID: 27876084

Aneurysmal SubArachnoid Hemorrhage-Red Blood Cell Transfusion And Outcome (SAHaRA): a pilot randomised controlled trial protocol.

First Author:

English SW

Journal:

BMJ Open

Year:

2016

Group:

English SW, Fergusson D, Chassé M, Turgeon AF, Lauzier F, Griesdale D, Algird A, Kramer A, Tinmouth A, Lum C, Sinclair J, Marshall S, Dowlatshahi D, Boutin A, Pagliarello G, McIntyre LA; Canadian Critical Care Trials Group. Aneurysmal SubArachnoid Hemorrhage-Red Blood Cell Transfusion And Outcome (SAHaRA): a pilot randomised controlled trial protocol. BMJ Open. 2016 Dec 7;6(12):e012623. PMID: 27927658

The Effect of Inadequate Initial Empiric Antimicrobial Treatment on Mortality in Critically Ill Patients with Bloodstream Infections: A Multi-Centre Retrospective Cohort Study.

First Author:

Savage RD

Journal:

PLoS One

Year:

2016

Group:

Savage RD, Fowler RA, Rishu AH, Bagshaw SM, Cook D, Dodek P, Hall R, Kumar A, Lamontagne F, Lauzier F, Marshall J, Martin CM, McIntyre L, Muscedere J, Reynolds S, Stelfox HT, Daneman N. The Effect of Inadequate Initial Empiric Antimicrobial Treatment on Mortality in Critically Ill Patients with Bloodstream Infections: A Multi-Centre Retrospective Cohort Study. PLoS One. 2016 May 6;11(5):e0154944. PMID:27152615

TryCYCLE: A Prospective Study of the Safety and Feasibility of Early In-Bed Cycling in Mechanically Ventilated Patients

First Author:

Kho ME

Journal:

PLoS One

Year:

2016

Group:

,

Kho ME, Molloy AJ, Clarke FJ, Ajami D, McCaughan M, Obrovac K, Murphy C, Camposilvan L, Herridge MS, Koo KK, Rudkowski J, Seely AJ, Zanni JM, Mourtzakis M, Piraino T, Cook DJ; Canadian Critical Care Trials Group.TryCYCLE: A Prospective Study of the Safety and Feasibility of Early In-Bed Cycling in Mechanically Ventilated Patients. PLoS One. 2016 Dec 28;11(12). PMID: 28030555

Re-evaluating the Inhibition of Stress Erosions (REVISE): a protocol for pilot randomized controlled trial.

First Author:

Alhazzani W

Journal:

Ann Saudi Med.

Year:

2016

Group:

,

Alhazzani W, Guyatt G, Marshall JC, Hall R, Muscedere J, Lauzier F, Thabane L, Alshahrani M, English SW, Arabi YM, Deane AM, Karachi T, Rochwerg B, Finfer S, Daneman N, Zytaruk N, Heel-Ansdell D, Cook D, Of OB. Re-evaluating the Inhibition of Stress Erosions (REVISE): a protocol for pilot randomized controlled trial. Ann Saudi Med. 2016 Nov-Dec;36(6):427-433. PMID: 27920416

The RECOVER Program: Disability Risk Groups & One Year Outcome after ≥ 7 Days of Mechanical Ventilation.

First Author:

Herridge MS

Journal:

Am J Respir Crit Care Med

Year:

2016

Group:

Herridge MS, Chu LM, Matte A, Tomlinson G, Chan L, Thomas C, Friedrich JO, Mehta S, Lamontagne F, Levasseur M, Ferguson ND, Adhikari NK, Rudkowski JC, Meggison H, Skrobik Y, Flannery J, Bayley M, Batt J, Dos Santos C, Abbey SE, Tan A, Lo V, Mathur S, Parotto M, Morris D, Flockhart L, Fan E, Lee CM, Wilcox ME, Ayas N, Choong K, Fowler R, Scales DC, Sinuff T, Cuthbertson BH, Rose L, Robles P, Burns S, Cypel M, Singer L, Chaparro C, Chow CW, Keshavjee S, Brochard L, Hebert P, Slutsky AS, Marshall JC, Cook D, Cameron JI; RECOVER Program Investigators (Phase 1: towards RECOVER) and the Canadian Critical Care Trials Group. The RECOVER Program: Disability Risk Groups & One Year Outcome after ≥ 7 Days of Mechanical Ventilation. Am J Respir Crit Care Med. 2016 Mar 14. [Epub ahead of print] PMID: 26974173

Early mobilization of critically ill adults: a survey of knowledge, perceptions and practices of Canadian physicians and physiotherapists.

First Author:

Koo KK

Journal:

CMAJ Open

Year:

2016

Group:

Koo KK, Choong K, Cook DJ, Herridge M, Newman A, Lo V, Guyatt G, Priestap F, Campbell E, Burns KE, Lamontagne F, Meade MO; Canadian Critical Care Trials Group. Early mobilization of critically ill adults: a survey of knowledge, perceptions and practices of Canadian physicians and physiotherapists. CMAJ Open. 2016 Aug 18;4(3):E448-E454. PMID: 27730109

Pandemic influenza 2009: Impact of vaccination coverage on critical illness in children, a Canada and France observational study

First Author:

Fléchelles, O

Journal:

World J Clin Pediatr

Year:

2016

Group:

Fléchelles, O, Brissaud, O, Fowler, R, Ducruet, T, Jouvet, P. The Pediatric Canadian Critical Care Trials Group H1N1 Collaborative and Groupe Francophone de Réanimation et Urgences Pédiatriques. Pandemic influenza 2009: Impact of vaccination coverage on critical illness in children, a Canada and France observational study. World J Clin Pediatr 2016 November 8; 5(4): 374-382

Prevalence, risk factors and outcomes associated with physical restraint use in mechanically ventilated adults

First Author:

Rose, L

Journal:

J Crit Care

Year:

2016

Group:

Rose L, Burry L, Mallick R, Luk E, Cook DJ, Fergusson ND, Meade M, Herridge M, Dodek PE, Burns KE, Granton J, Ferguson ND, Devlin J, Steinberg M, Keenan S, Reynolds S, Tanios M, Fowler R, Jacka M, Olafson K, Skrobik Y, Mehta S for the SLEAP investigators and Canadian Critical Care Trials Group. Prevalence, risk factors and outcomes associated with physical restraint use in mechanically ventilated adults. J Crit Care. 2016 Feb;31(1):31-5.

Prevalence, Risk Factors, and Outcomes of Delirium in Mechanically Ventilated Adults.

First Author:

Mehta S

Journal:

Crit Care Med

Year:

2015

Group:

,

Mehta S, Cook D, Devlin JW, Skrobik Y, Meade M, Fergusson D, Herridge M, Steinberg M, Granton J, Ferguson N, Tanios M, Dodek P, Fowler R, Burns K, Jacka M, Olafson K, Mallick R, Reynolds S, Keenan S, Burry L; for the SLEAP Investigators and the Canadian Critical Care Trials Group. Prevalence, Risk Factors, and Outcomes of Delirium in Mechanically Ventilated Adults.Crit Care Med. 2015, 43(3):557-66. PMID: 25493968

Failure of Anticoagulant Thromboprophylaxis: Risk Factors in Medical-Surgical Critically Ill Patients.

First Author:

Lim W

Journal:

Crit Care Med

Year:

2015

Group:

Lim W, Meade M, Lauzier F, Zarychanski R, Mehta S, Lamontagne F, Dodek P, McIntyre L, Hall R, Heels-Ansdell D, Fowler R, Pai M, Guyatt G, Crowther MA, Warkentin TE, Devereaux PJ, Walter SD, Muscedere J, Herridge M, Turgeon AF, Geerts W, Finfer S, Jacka M, Berwanger O, Ostermann M, Qushmaq I, Friedrich JO, Cook DJ; for the PROphylaxis for ThromboEmbolism in Critical Care Trial Investigators, the Canadian Critical Care Trials Group, and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Failure of Anticoagulant Thromboprophylaxis: Risk Factors in Medical-Surgical Critically Ill Patients.Crit Care Med. 2015; 43(2):401-10. PMID: 25474533

Nonbeneficial Treatment Canada: Definitions, Causes, and Potential Solutions From the Perspective of Healthcare Practitioners.

First Author:

Downar J

Journal:

Crit Care Med

Year:

2015

Group:

Downar J, You JJ, Bagshaw SM, Golan E, Lamontagne F, Burns K, Sridhar SK, Seely A, Meade MO, Fox-Robichaud A, Cook D, Turgeon AF, Dodek P, Xiong W, Fowler R; on behalf of the Canadian Critical Care Trials Group.Nonbeneficial Treatment Canada: Definitions, Causes, and Potential Solutions From the Perspective of Healthcare Practitioners.Crit Care Med. 2015 43(2):270-81. PMID: 25377017

Clinician perspectives on protocols designed to minimize sedation.

First Author:

Rose L

Journal:

J Crit Care

Year:

2015

Group:

,

Rose L, Fitzgerald E, Cook D, Kim S, Steinberg M, Devlin JW, Ashley BJ, Dodek P, Smith O, Poretta K, Lee Y, Burns K, Harvey J, Skrobik Y, Fergusson D, Meade M, Kraguljac A, Burry L, Mehta S; SLEAP Investigators and the Canadian Critical Care Trials Group.Clinician perspectives on protocols designed to minimize sedation.J Crit Care. 30(2):348-52. PMID: 25466317

Coenrollment in a Randomized Trial of High-Frequency Oscillation: Prevalence, Patterns, Predictors, and Outcomes.

First Author:

Cook DJ

Journal:

Crit Care Med

Year:

2015

Group:

,

Cook DJ, Ferguson ND, Hand L, Austin P, Zhou Q, Adhikari NK, Danesh V, Arabi Y, Matte AL, Clarke FE, Mehta S, Smith O, Wise MP, Friedrich JO, Keenan SP, Hanna S, Meade MO; for the OSCILLation for ARDS Treated Early Investigators and the Canadian Critical Care Trials Group.Coenrollment in a Randomized Trial of High-Frequency Oscillation: Prevalence, Patterns, Predictors, and Outcomes. Crit Care Med. 2015 Feb;43(2):328-38 PMID: 25393702

Functional Recovery Following Critical Illness in Children: The "Wee-Cover" Pilot Study.

First Author:

Choong K

Journal:

Pediatr Crit Care Med

Year:

2015

Group:

,

Choong K, Al-Harbi S, Siu K, Wong K, Cheng J, Baird B, Pogorzelski D, Timmons B, Gorter JW, Thabane L, Khetani M; on behalf of the Canadian Critical Care Trials Group.Functional Recovery Following Critical Illness in Children: The "Wee-Cover" Pilot Study. Pediatr Crit Care Med. 2015 May;16(4):310-8. PMID: 25651047

Admission of the very elderly to the intensive care unit: Family members' perspectives on clinical decision-making from a multicenter cohort study.

First Author:

Heyland DK

Journal:

Palliat Med.

Year:

2015

Group:

Heyland DK, Dodek P, Mehta S, Cook D, Garland A, Stelfox HT, Bagshaw SM, Kutsogiannis DJ, Burns K, Muscedere J, Turgeon AF, Fowler R, Jiang X, Day AG; on behalf of the Canadian Critical Care Trials Group and the Canadian Researchers at the End of Life Network (CARENET).Admission of the very elderly to the intensive care unit: Family members' perspectives on clinical decision-making from a multicenter cohort study. Palliat Med. 2015 Apr;29(4):324-35. PMID: 25645668

Is There a Role for Physician Involvement in Introducing Research to Surrogate Decision Makers in the Intensive Care Unit? (The Approach Trial: A Mixed Methods Study)

First Author:

Burns KEA

Journal:

Intensive Care Med

Year:

2015

Group:

Burns KEA, Rizvi L, Smith O, Lee Y, Lee J, Wang M, Brown M, Parker M, Premji A, Leung D, Hammond Mobilio M, Gotlib-Conn L, Nisenbaum R, Santos M, Li Y,  Mehta S.  Is There a Role for Physician Involvement in Introducing Research to Surrogate Decision Makers in the Intensive Care Unit? (The Approach Trial: A Mixed Methods Study) Intensive Care Med 2015;41:58-67. PMID: 25491659

A Scoping Review of Patient Discharge from Intensive Care: Opportunities and Tools to Improve Care

First Author:

Stelfox H

Journal:

Chest

Year:

2015

Group:

Stelfox H, Lane D, Boyd J, Taylor S, Perrier L, Straus S, Zygun D, Zuege D. A Scoping Review of Patient Discharge from Intensive Care: Opportunities and Tools to Improve Care. Chest. 2015;147(2):317-27. PMID: 25210942

Stakeholder Views regarding Patient Discharge from Intensive Care: Suboptimal Quality and Opportunities for Improvement.

First Author:

Li P

Journal:

Can Respir J.

Year:

2015

Group:

Li P, Boyd JM, Ghali WA, Stelfox HT. Stakeholder Views regarding Patient Discharge from Intensive Care: Suboptimal Quality and Opportunities for Improvement. Can Respir J. 2015, 22(2):115-4. PMID: 25522304

Implementation and Evaluation of a Wiki Involving Multiple Stakeholders Including Patients in the Promotion of Best Practices in Trauma Care:The WikiTrauma Interrupted Time Series Protocol.

First Author:

Archambault P

Journal:

JMIR Res Protoc

Year:

2015

Group:

Archambault PM, Turgeon AF, Witteman HO, Lauzier F, Moore L, Lamontagne F, Horsley T, Gagnon M-P, Droit A, Weiss M, Tremblay S, Lachaine J, Le Sage N, Émond M, Berthelot S, Plaisance A, Lapointe J, Razek T, van de Belt TH, Brand K, Bérubé M, Clément J, Grajales FJ, Eysenbach G, Kuziemsky  G, Friedman D, Lang E, Muscedere J, Rizoli S, Roberts DJ, Scales DC, Sinuff T, Stelfox HT, Gagnon I, Chabot C, Grenier R, Légaré F, Canadian Critical Care Trials Group. Implementation and Evaluation of a Wiki Involving Multiple Stakeholders Including Patients in the Promotion of Best Practices in Trauma Care:The WikiTrauma Interrupted Time Series Protocol. JMIR Res Protoc 2015,4(1): e21p.2.

The efficacy and safety of heparin in patients with sepsis: A systematic review and meta-analysis.

First Author:

Zarychanski R

Journal:

Crit Care Med

Year:

2015

Group:

Zarychanski R, Abou-Setta AM, Kanji S, Turgeon AF, Kumar A, Houston DS, Rimmer E, Houston BL, McIntyre L, Fox-Robichaud AE, Hébert P, Cook DJ, Fergusson DA, for the Canadian Critical Care Trials Group.  The efficacy and safety of heparin in patients with sepsis: A systematic review and meta-analysis.  Critical Care Medicine. 2015;43(3):511-8.  PMID:25493972

Changing support needs of survivors of complex critical illness and their family caregivers across the care continuum: A qualitative pilot study of Towards RECOVER

First Author:

Czerwonka AI

Journal:

J Crit Care

Year:

2015

Group:

Czerwonka AI, Herridge MS, Chan L, Chu LM, Matte A, Cameron JI. Changing support needs of survivors of complex critical illness and their family caregivers across the care continuum: A qualitative pilot study of Towards RECOVER. J Crit Care. 2015;30(2):242-9. PMID: 25466314