Publications

Lauzier F, Muscedere J, Deland E, Kutsogiannis DJ, Jacka M, Heels-Ansdell D, Crowther M, Cartin-Ceba R, Cox MJ, Zytaruk N, Foster D, Sinuff T, Clarke F, Thompson P, Hanna S, Cook D; Co-operative Network of Critical Care Knowledge Translation for Thromboprophylaxis (CONECCKT-T) Investigators; Canadian Critical Care Trials Group. Thromboprophylaxis patterns and determinants in critically ill patients: a multicenter audit. Crit Care. 2014;18(2):R82. PMID:24766968

Cook D, Duffett M2, Lauzier F3, Ye C4, Dodek P5, Paunovic B6, Fowler R7, Kho ME8, Foster D9, Stelfox T10, Sinuff T7, Zytaruk N4, Clarke F4, Wood G11, Cox M12, Kutsiogiannis J13, Jacka M13, Roussos M14, Kumar H15, Guyatt G16; CONECCKT-T (Co-operative Network of Critical Care Knowledge Translation for Thromboprophylaxis) Investigators; Canadian Critical Care Trials Group.Barriers and facilitators of thromboprophylaxis for medical-surgical intensive care unit patients: a multicenter survey. J Crit Care. 2014;29(3):471. PMID: 24629574

Cook D, McDonald E, Smith O, Zytaruk N, Heels-Ansdell D, Watpool I, McArdle T, Matte A, Clarke F, Vallance S, Finfer S, Galt P, Crozier T, Fowler R, Arabi Y, Woolfe C, Orford N, Hall R, Adhikari N, Ferland MC, Marshall JD, Meade M for the PROTECT Investigators, CCCTG and ANZICS-CTG. Coenrolment of Critically Ill Patients into Multiple Studies: Patterns, Predictors and Consequences. Crit Care 2013;17:R1-R8.

Smith OM, McDonald E, Zytaruk N, Foster D, Matte A, Clarke F, Meade L, O’Callaghan N, Vallance S, Galt P, Rajbhandari D, Rocha M, Mehta S, Ferguson ND, Hall R, Fowler R, Burns K, Qushmaq I, Ostermann M, Heels-Ansdell, Cook DJ for the PROTECT Research Coordinators, PROTECT Investigators, Canadian Critical Care Trials Group, and the Australian, New Zealand Intensive Care Society Clinical Trials Group. Rates and determinants of informed consent: A case study of an international thromboprophylaxis trial. J Crit Care 2013;28: 28-39. PMID: 23089679

Smith OM, Wald R, Adhikari NK, Pope K, Weir MA, Bagshaw SM; Canadian Critical Care Trials Group. Standard versus accelerated initiation of renal replacement therapy in acute kidney injury (STARRT-AKI): study protocol for a randomized controlled trial. Trials. 2013;14:320. PMID: 24093950

Ferguson ND, Cook DJ, Guyatt GH, Mehta S, Hand L, Austin P, Zhou Q, Matte A, Walter SD, Lamontagne F, Granton JT, Arabi YM, Arroliga AC, Stewart TE, Slutsky AS, Meade MO; OSCILLATE Trial Investigators; Canadian Critical Care Trials Group.High-frequency oscillation in early acute respiratory distress syndrome.N Engl J Med. 2013 Feb 28;368(9):795-805. PMID: 23339639

Arnold DM, Lauzier F, Rabbat C, Zytaruk N, Barlow Cash B, Clarke F, Heels-Ansdell D, Guyatt G, Walter SD, Davies A, Cook DJ; PROTECT Investigators, on behalf of the Canadian Critical Care Trials Group and the Australian and New Zealand Intensive Care Society Clinical Trials Group.Adjudication of bleeding outcomes in an international thromboprophylaxis trial in critical illness.Thromb Res. 2013 Mar;131(3):204-9. PMID: 23317632

Lauzier F, Arnold DM, Rabbat C, Heels-Ansdell D, Zarychanski R, Dodek P, Ashley BJ, Albert M, Khwaja K, Ostermann M, Skrobik Y, Fowler R, McIntyre L, Nates JL, Karachi T, Lopes RD, Zytaruk N, Finfer S, Crowther M, Cook D. Risk factors and impact of major bleeding in critically ill patients receiving heparin thromboprophylaxis. Intensive Care Med. 2013;39(12):2135-43. PMID: 23942857

Smith OM, McDonald E, Zytaruk N, Foster D, Matte A, Clarke F, Fleury S, Krause K, McArdle T, Skrobik Y, Cook DJ.Enhancing the informed consent process for critical care research: strategies from a thromboprophylaxis trial. Intensive Crit Care Nurs. 2013;29(6):300-9. PMID: 23871290

Lutz K, Wilton K, Zytaruk N, Julien L, Hall R, Harvey J, Skrobik Y, Vlahakis N, Meade L, Matte A, Meade M, Burns KB, Albert M, Barlow Cash B, Vallance S, Klinger J, Heels-Ansdell D, Cook D, for the PROTECT Investigators in collaboration with the Canadian Critical Care Trials Group and ANZICS-CTG. Research Ethics Board Approval. For An International Thromboprophylaxis Trial. J Crit Care. 2012;27(3):225-31. PMID:22305662

Mehta S, Burry L, Cook D, Fergusson D, Steinberg M, Granton J, Herridge M, Ferguson N, Devlin J, Tanios M, Dodek P, Fowler R, Burns K, Jacka M, Olafson K, Skrobik Y, Hebert P, Sabri E, and Meade M, for the SLEAP Investigators and the Canadian Critical Care Trials Group. Daily sedation interruption in mechanically ventilated critically ill patients cared for with a sedation protocol: a randomized controlled trial. JAMA. 2012;308(19):1985-92. PMID: 23180503

L Rose, R Maunder, J Hunter, A Day, M Steinberg, M Herridge, J Devlin, P Dodek, L Burry, S Mehta, for the Canadian Critical Care Trials Group. Sleep, cognitive and psychological morbidity following sedation protocol and daily sedative interruption vs sedation protocol alone in critically ill, mechanically ventilated adults (SLEAP-SCP). Crit Care Med 2012; 40 (12 Suppl.): Abstract 1104

NICE-SUGAR Study Investigators, Finfer S, Liu B, Chittock DR, Norton R, Myburgh JA, McArthur C, Mitchell I, Foster D, Dhingra V, Henderson WR, Ronco JJ, Bellomo R, Cook D, McDonald E, Dodek P, Hébert PC, Heyland DK, Robinson BG.Hypoglycemia and risk of death in critically ill patients.N Engl J Med. 2012 Sep 20;367(12):1108-18. PMID: 22992074

Griesdale DE, Chau A, Isac G, Ayas N, Foster D, Irwin C, Choi P; for the Canadian Critical Care Trials Group. Video-laryngoscopy versus direct laryngoscopy in critically ill patients: a pilot randomized trial. Can J Anaesth. 2012 Aug 30

Katsios C, Griffith L, Spinella P, Lacroix J, Crowther M, Hebert P, Meade M, Geerts W, Rabbat C, Cook D for the Canadian Critical Care Trials Group. Red blood cell transfusion and increased length of storage are not associated with deep vein thrombosis in medical-surgical critically ill patients: a prospective observational cohort study. Crit Care 2011; 15:R263. PMID: 22044745

Ethier C, Burry L, Martinez-Motta C, Tirgari S, Jiang D, McDonald E, Granton J, Cook D, Mehta S, for the Canadian Critical Care Trials Group. Recall of ICU stay in patients managed with a Sedation Protocol or a Sedation Protocol with Daily Sedative Interruption: A Pilot Study. J of Crit Care 2011;26:127-132. Epub Oct 1, 2010. PMID: 20889289

Crowther MA, Cook DJ, Albert M, Williamson D, Meade M, Granton J, Skrobik Y, Langevin S, Mehta S, Hebert PC, Guyatt GH, Geerts W, Rabbat C, Douketis J, Zytaruk N, Sheppard J, Greinacher A, Warkentin TE for the Canadian Critical Care Trials Group. The 4Ts scoring system for heparin induced thrombocytopenia in medical-surgical ICU patients. J Crit Care 2010; 25(2):287-293. doi:10.1016/j.jcrc.2009.12.006 PMID: 20149589

Cook D, Sinuff T, Zytaruk N, Rabbat C, Lee A, O'Donnell M, Thabane L, Linkins L, Treleaven D, Patel R, Meade M, Crowther M, Marshall JC, Douketis J; DIRECT Investigators and Canadian Critical Care Trials Group. Event adjudication and data monitoring in an intensive care unit observational study of thromboprophylaxis.J Crit Care. 2009;24(2):168-75. PMID: 19327956

Douketis J, Cook D, Meade M, Guyatt G, Geerts W, Skrobik Y, Albert M, Granton J, Hebert PC, Pagliarello G, Marshall JC, Fowler R, Freitag A, Rabbat C, Anderson D, Zytaruk N, Heels-Ansdell D, Crowther MA for the Canadian Critical Care Trials Group. Renal Insufficiency with the Low-molecular-weight Heparin Dalteparin: An Assessment of Safety and Pharmacodynamics. The DIRECT (Dalteparin’s Influence on REnally Compromised anti-Ten-A) Study. Arch Intern Med 2008;168(16):1805-1812. PMID: 18779469

Mehta S, Burry L, Martinez-Motta C, Stewart TE, Hallett D, McDonald E, Clarke F, MacDonald R, Granton J, Matte A, Wong C, Suri A, Cook D for the Canadian Critical Care Trials Group.  A randomized trial of daily awakening in critically ill patients managed with a sedation protocol – A pilot study. Crit Care Med 2008;36(7):2092-2099. PMID: 18552687

Cook DJ, Blythe D, Rischbieth A, Hebert PC, Zytaruk N, Menon K, Erikson S, Fowler R, Heels-Ansdell D, Meade MO for the Canadian Critical Care Trials Group. Enrolment of ICU Patients into Clinical Studies: A Tri-national Survey. Crit Care Med 2008; 36(7):2100-2105. PMID: 18552686

Cook D, Douketis J, Meade M, Guyatt G, Zytaruk N, Granton J, Skrobik Y, Albert M, Fowler R, Hebert P, Pagliarello G, Friedrich J, Freitag A, Karachi T, Rabbat C, Heels-Ansdell D, Geerts W, Crowther M; Canadian Critical Care Trials Group.Venous thromboembolism and bleeding in critically ill patients with severe renal insufficiency receiving dalteparin thromboprophylaxis: prevalence, incidence and risk factors.Crit Care. 2008;12(2):R32. PMID: 18315876

Cook DJ, Rocker G, Marshall J, Griffith L, McDonald E, Guyatt GH for the Level of Care Study Investigators and the Canadian Critical Care Trials Group. Levels of Care in the Intensive Care Unit: A Research Program. Am J Crit Care 2006 May;15(3):269-79. PMID: 16632769

Cheung AM, Tansey CM, Tomlinson G, Diaz-Granados N, Matte-Martyn A, Mehta S, Mazer D, Guest CB, Stewart TE, Al-Saidi F, Cooper AB, Cook DJ, Slutsky AS, Herridge MS for The Canadian Critical Care Trials Group. Two-year health care utilization, costs and outcomes in survivors of the acute respiratory distress syndrome. Am J Resp Crit Care Med 2006; 174:538-544. PMID: 16763220