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Importance of nationally coordinated data collection and quality improvement networks

First Author:

Seely AJE

Journal:

Can J Resp, Crit, Sleep Med

Year:

2021

Group:

Seely, Andrew JE and Robert Fowler. Importance of nationally coordinated data collection and quality improvement networks. Canadian Journal of Respiratory, Critical Care and Sleep Medicine. Published online 17 August, 2021.

Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients A Randomized Clinical Trial

First Author:

Johnstone J

Journal:

JAMA

Year:

2021

Group:

Johnstone J, Meade M, Lauzier F, Marshall J, Duan E, Dionne J, Arabi YM, Heels-Ansdell D, Thabane L, Lamarche D; Surette M, Zytaruk N, Mehta S, Dodek P, McIntyre L, English S, Rochwerg B, Karachi T, Henderson S; Wood G, Ovakim D, Herridge M, Granton J, Wilcox E; Goffi A, Stelfox HT, Niven D, Muscedere J, Lamontagne F, D’Aragon F, St.-Arnaud C, Ball I, Nagpal D, Girard M, Aslanian P, Charbonney E, Williamson D, Sligl W, Friedrich J, Adhikari NK, Marquis F, Archambault P, Khwaja K, Kristof A, Kutsogiannis J, Zarychanski R, Paunovic B, Reeve B, Lellouche F, Hosek P, Tsang J, Binnie A, Trop S, Loubani O, Hall R, Cirone R, Reynolds S, Lysecki P, Golan E, Cartin-Ceba R, Taylor R, Cook D; for the Prevention of Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT) Investigators and the Canadian Critical Care Trials Group. Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients: A Randomized Clinical Trial. JAMA 2021; 326(11):1024-1033. doi:10.1001/jama.2021.13355

Consent models in Canadian critical care randomized controlled trials: a scoping review

First Author:

O'Hearn, K

Journal:

Can J Anesth

Year:

2021

Group:

, ,

O’Hearn K, Gibson J, Krewulak K, Porteous R, Saigle V, Sampson M, Tsampalieros A, Barrowman N, Cameron S, and the Canadian Critical Care Trials Group.Consent models in Canadian critical care randomized controlled trials: a scoping review. Can. J Anesthesia; 14 Dec. 2021

Impact of Restricted Visitation Policies During the First Wave of the COVID-19 Pandemic on Communication Between Critically Ill Patients, Families and Clinicians: A Qualitative Interview Study

First Author:

Krewulak K

Journal:

Ann Am Thorac Soc

Year:

2021

Group:

Krewulak KD, Jaworska  N, Spence KL, Mizen SJ, Kupsch  S, Stelfox HT, Parsons Leigh J, Fiest KM, and Canadian Critical Care Trials Group. Impact of Restricted Visitation Policies During the First Wave of the COVID-19 Pandemic on Communication Between Critically Ill Patients, Families and Clinicians: A Qualitative Interview Study. Dec. 16, 2021 DOI: 10.1513/AnnalsATS.202107-877OC PMID: 34914537

CCEDRRN COVID-19 Infection Score (CCIS): development and validation in a Canadian cohort of a clinical risk score to predict SARS-CoV-2 infection in patients presenting to the emergency department with suspected COVID-19

First Author:

McRae AD

Journal:

BMJ Open

Year:

2021

Group:

McRae AD, Hohl CM, Rosychuk R, Vatanpour S, Ghaderi G, Archambault PM, Brooks SC, Cheng I, Davis P, Hayward J, Lang E, Ohle R, Rowe B, Welsford M, Yadav K, Morrison LJ, Perry J, Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN) investigators for the Network of Canadian Emergency Researchers and the Canadian Critical Care Trials Group. CCEDRRN COVID-19 Infection Score (CCIS): development and validation in a Canadian cohort of a clinical risk score to predict SARS-CoV-2 infection in patients presenting to the emergency department with suspected COVID-19 PMID: 34857584  PMCID: PMC8640195  DOI: 10.1136/bmjopen-2021-055832 2021 Dec 2;11 (12):e055832

Clinical evaluation and ancillary testing for the diagnosis of death by neurologic criteria: a cross-sectional survey of Canadian intensivists

First Author:

Chassé M

Journal:

Can J Anaesthesia

Year:

2021

Group:

,

Chassé M, Briard JN, Yu M, Carvalho LP, English SW, D’Aragon F, Lauzier F, Turgeon AF, Dhanani S, McIntyre L, Shemie SD, Knoll G, Fergusson DA, Anthony SJ, Weiss MJ on behalf of the Canadian Critical Care Trials Group. Canadian Journal of Anaesthesia (2021).

Music Use for Sedation in Critically ill Children (MUSiCC trial): a pilot randomized controlled trial

First Author:

Garcia Guerra G

Journal:

Journal of Intensive Care

Year:

2021

Group:

,

Garcia Guerra G, Joffe AR, Sheppard C, Hewson K, Dinu IA, Hajihosseini M, deCaen A, Jou H, Hartling L,  Vohra S & the Canadian Critical Care Trials Group. Music Use for Sedation in Critically ill Children (MUSiCC trial): a pilot randomized controlled trial. Journal of Intensive Care volume 9, Article number: 7 (2021) Published: 12 January 2021

CardiO Cycle: a pilot feasibility study of in-bed cycling in critically ill patients post cardiac surgery

First Author:

Newman ANL

Journal:

Pilot and Feasibility Studies

Year:

2021

Group:

,

Newman ANL, Kho ME, Harris JE, Zamir N, McDonald E, Fox-Robichaud A & Solomon P for the Canadian Critical Care Trials Group. CardiO Cycle: a pilot feasibility study of in-bed cycling in critically ill patients post cardiac surgery. Pilot and Feasibility Studies volume 7, Article number: 13 (2021)  Published: 07 January 2021

Utilization and effect of neuromuscular blockade in a randomized trial of high-frequency oscillation

First Author:

Mehta S

Journal:

J Crit Care

Year:

2021

Group:

Mehta S, Zhou Q, Pinto R, Friedrich JO, Lamontagne F, Ferguson ND, Meade MO, Adhikari NKJ; OSCILLATE Investigators and the Canadian Critical Care Trials Group. Utilization and effect of neuromuscular blockade in a randomized trial of high-frequency oscillation. J Crit Care. 2021 Dec;66:86-92. PMID: 34474282

Feasibility of implementing Extubation Advisor, a clinical decision support tool to improve extubation decision-making in the ICU: a mixed-methods observational study

First Author:

Sarti, AJ

Journal:

BMJ Open

Year:

2021

Group:

Sarti AJ, Zheng K, Herry CL, Sutherland S, Scales NB, Watpool I, Porteous R, Hickey M, Anstee C, Fazekas A, Ramsay T, Burns KE, Seely AJ; Canadian Critical Care Trials Group. Feasibility of implementing Extubation Advisor, a clinical decision support tool to improve extubation decision-making in the ICU: a mixed-methods observational study. BMJ Open. 2021 Aug 12;11(8):e045674. PMID: 34385234

Development of the Canadian COVID-19 Emergency Department Rapid Response Network population-based registry: a methodology study

First Author:

Hohl, CM

Journal:

CMAJ Open

Year:

2021

Group:

Hohl CM, Rosychuk RJ, McRae AD, Brooks SC, Archambault P, Fok PT, Davis P, Jelic T, Turner JP, Rowe BH, Mercier É, Cheng I, Taylor J, Daoust R, Ohle R, Andolfatto G, Atzema C, Hayward J, Khangura JK, Landes M, Lang E, Martin I, Mohindra R, Ting DK, Vaillancourt S, Welsford M, Brar B, Dahn T, Wiemer H, Yadav K, Yan JW, Stachura M, McGavin C, Perry JJ, Morrison LJ; Canadian COVID-19 Emergency Department Rapid Response Network investigators and for the Network of Canadian Emergency Researchers and the Canadian Critical Care Trials Group. Development of the Canadian COVID-19 Emergency Department Rapid Response Network population-based registry: a methodology study. CMAJ Open. 2021 Mar 17;9(1):E261-E270. PMID: 33731427

Moral Distress and Other Wellness Measures in Canadian Critical Care Physicians

First Author:

Dodek PM

Journal:

Ann Am Thorac Soc

Year:

2021

Group:

,

Dodek PM, Cheung EO, Burns KEA, Martin CM, Archambault PM, Lauzier F, Sarti AJ, Mehta S, Fox-Robichaud AE, Seely AJE, Parshuram C, Garros D, Withington DE, Cook DJ, Piquette D, Carnevale FA, Boyd JG, Downar J, Kutsogiannis DJ, Chassé M, Fontela P, Fowler RA, Bagshaw S, Dhanani S, Murthy S, Gehrke P, Fujii T. Moral Distress and Other Wellness Measures in Canadian Critical Care Physicians. Ann Am Thorac Soc. 2021 Aug;18(8):1343-1351. PMID: 33356972

Lessening Organ dysfunction with VITamin C (LOVIT): protocol for a randomized controlled trial

First Author:

Masse MH

Journal:

Trials

Year:

2020

Group:

,

Masse MH, Ménard J, Sprague S, Battista MC, Cook DJ, Guyatt GH, Heyland DK, Kanji S, Pinto R, Day AG, Cohen D, Annane D, McGuinness S, Parke R, Carr A, Arabi Y, Vijayaraghavan BKT, D'Aragon F, Carbonneau É, Maslove D, Hunt M, Rochwerg B, Millen T, Chassé M, Lebrasseur M, Archambault P, Deblois E, Drouin C, Lellouche F, Lizotte P, Watpool I, Porteous R, Clarke F, Marinoff N, Belley-Côté É, Bolduc B, Walker S, Iazzetta J, Adhikari NKJ, Lamontagne F; Canadian Critical Care Trials Group. Lessening Organ dysfunction with VITamin C (LOVIT): protocol for a randomized controlled  trial. Trials. 2020 Jan 8;21(1):42. PMID: 31915072

A pilot randomized controlled trial of 7 versus 14 days of antibiotic treatment for bloodstream infection on non-intensive care versus intensive care wards

First Author:

Daneman N

Journal:

Trials

Year:

2020

Group:

Daneman N, Rishu AH, Pinto R, Arabi Y, Belley-Cote EP, Cirone R, Downing M, Cook DJ, Hall R, McGuinness S, McIntyre L, Muscedere J, Parke R, Reynolds S, Rogers BA, Shehabi Y, Shin P, Whitlock R, Fowler RA; Canadian Critical Care Trials Group. A pilot randomized controlled trial of 7 versus 14 days of antibiotic treatment for bloodstream infection on non-intensive care versus intensive care wards. Trials. 2020 Jan 15;21(1):92. PMID: 31941546

Motivators and Stressors for Canadian Research Coordinators in Critical Care: The MOTIVATE Survey

First Author:

McDonald E

Journal:

Am J Crit Care

Year:

2020

Group:

,

McDonald E, Zytaruk N, Heels-Ansdell D, Smith O, Borges D, Hand L, Clarke F, Nassar A, Bennardo M, Cook D; Canadian Critical Care Research Coordinators’ Group. Motivators and Stressors for Canadian Research Coordinators in Critical Care: The MOTIVATE Survey.Am J Crit Care. 2020 Jan 1;29(1):41-48. PMID: 31968081

Effect of Reduced Exposure to Vasopressors on 90-Day Mortality in Older Critically Ill Patients With Vasodilatory Hypotension: A Randomized Clinical Trial

First Author:

Lamontagne F

Journal:

JAMA

Year:

2020

Group:

Effect of Reduced Exposure to Vasopressors on 90-Day Mortality in Older Critically Ill Patients With Vasodilatory Hypotension: A Randomized Clinical Trial. Lamontagne F, Richards-Belle A, Thomas K, Harrison DA, Sadique MZ, Grieve RD, Camsooksai J, Darnell R, Gordon AC, Henry D, Hudson N, Mason AJ, Saull M, Whitman C, Young JD, Rowan KM, Mouncey PR; 65 trial investigators. JAMA. 2020 Feb 12. doi: 10.1001/jama.2020.0930. PMID: 32049269

Music Use for Sedation in Critically ill Children (MUSiCC trial): study protocol for a pilot randomized controlled trial

First Author:

Garcia Guerra G

Journal:

Pilot Feasibility Stud.

Year:

2020

Group:

,

Garcia Guerra G, Joffe A, Sheppard C, Hewson K, Dinu IA, de Caen A, Jou H, Hartling L, Vohra S; Canadian Critical Care Trials Group. Music Use for Sedation in Critically ill Children (MUSiCC trial): study protocol for a pilot randomized controlled trial. Pilot Feasibility Stud. 2020 Feb 25;6:31. doi: 10.1186/s40814-020-0563-x. eCollection 2020.. PMID: 32128249

Timing of Initiation of Renal-Replacement Therapy in Acute Kidney Injury

First Author:

STARRT-AKI Investigators

Journal:

N Engl J Med.

Year:

2020

Group:

STARRT-AKI Investigators; Canadian Critical Care Trials Group; Australian and New Zealand Intensive Care Society Clinical Trials Group; United Kingdom Critical Care Research Group; Canadian Nephrology Trials Network; Irish Critical Care Trials Group, Bagshaw SM, Wald R, Adhikari NKJ, Bellomo R, da Costa BR, Dreyfuss D, Du B, Gallagher MP, Gaudry S, Hoste EA, Lamontagne F, Joannidis M, Landoni G, Liu KD, McAuley DF, McGuinness SP, Neyra JA, Nichol AD, Ostermann M, Palevsky PM, Pettilä V, Quenot JP, Qiu H, Rochwerg B, Schneider AG, Smith OM, Thomé F, Thorpe KE, Vaara S, Weir M, Wang AY, Young P, Zarbock A.Timing of Initiation of Renal-Replacement Therapy in Acute Kidney Injury. N Engl J Med. 2020 Jul 16;383(3):240-251.

Data initiatives supporting critical care research and quality improvement in Canada: an environmental scan and narrative review

First Author:

Chornenki JN

Journal:

Can J Anaesth.

Year:

2020

Chornenki JN, Liaw P, Bagshaw S, Burns K, Dodek P, English S, Fan E, Ferrari N, Fowler R, Fox-Robichaud A, Garland A, Green R, Hebert P, Kho M, Martin C, Maslove D, McDonald E, Menon K, Murthy S, Muscedere J, Scales D, Stelfox HT, Wang HT, Weiss M; Canadian Critical Care Trials Group (CCCTG) and Canadian Critical Care Translational Biology Group (CCCTBG). Data initiatives supporting critical care research and quality improvement in Canada: an environmental scan and narrative review. Can J Anaesth. 2020 Apr;67(4):475-484.

Survey of Canadian critical care physicians' knowledge and attitudes towards legislative aspects of the deceased organ donation system

First Author:

Weiss MJ

Journal:

Can J Anaesth.

Year:

2020

Group:

,

Weiss MJ, English SW, D'Aragon F, Lauzier F, Turgeon AF, Dhanani S, McIntyre L, Carvalho LP, Yu M, Shemie SD, Knoll G, Fergusson DA, Anthony SJ, Haj-Moustafa A, Hartell D, Mohr J, Chassé M; Canadian Critical Care Trials Group.Survey of Canadian critical care physicians' knowledge and attitudes towards legislative aspects of the deceased organ donation system. Can J Anaesth. 2020 Oct;67(10):1349-1358.

Adapting two American Decision Aids for Mild Traumatic Brain Injury to the Canadian Context Using the Nominal Group Technique

First Author:

Ghandour EK

Journal:

Patient

Year:

2020

Group:

Ghandour EK, Lelaidier Hould L, Fortier FA, Gélinas V, Melnick ER, Hess EP, Lang ES, Gravel J, Perry JJ, Le Sage N, Truchon C, LeBlanc A, Dubrovsky AS, Gagnon MP, Ouellet MC, Gagnon I, McKenna S, Légaré F, Sauvé L, van de Belt TH, Kavanagh É, Paquette L, Verrette AC, Plante P, Riopelle RJ, Archambault PM; Canadian Critical Care Trials Group, the Canadian Traumatic Brain Injury Research Consortium and the Network of Canadian Emergency Researchers. Adapting two American Decision Aids for Mild Traumatic Brain Injury to the Canadian Context Using the Nominal Group Technique. Patient. 2020 Oct 20. doi: 10.1007/s40271-020-00459-y.

International Survey on Determinants of Antibiotic Duration and Discontinuation in Pediatric Critically Ill Patients

First Author:

Noel KC

Journal:

Pediatr. Crit Care Med

Year:

2020

Group:

,

KC Noël, J Papenburg, J Lacroix, C Quach, S O'Donnell, M Gonzales, DF Willson, E Gilfoyle, JD McNally, S Reynolds, Y Kazzaz, A Kawaguchi, M Sato, L Kongkiattikul, S Leteurtre, F Dubos, Y Karaca, F Chiusolo, J Piva, N Dendukuri, PS Fontela, Canadian Critical Care Trials Group (CCCTG) and the Pediatric Lung Injury and Sepsis Investigators (PALISI) Network. International Survey on Determinants of Antibiotic Duration and Discontinuation in Pediatric Critically Ill Patients. Pediatr. Crit Care Med. 2020; Sep;21(9):e696-e706 PMID: 32639469

Agitation, confusion, and aggression in critically ill traumatic brain injury-a pilot cohort study (ACACIA-PILOT)

First Author:

Williamson, DR

Journal:

Pilot and Feasibility Studies

Year:

2020

Group:

Williamson DR, Cherifa SI, Frenette AJ, Mitjans MS, Charbonney E, Cataford G, Williams V, Palacios JL, Burry L, Mehta S, Arbour C & F. Bernard for the Canadian Critical Care Trials Group. Agitation, confusion, and aggression in critically ill traumatic brain injury-a pilot cohort study (ACACIA-PILOT). Pilot and Feasibility Studies volume 6, Article number: 193 (2020)

Prevention of post-cardiac surgery vitamin D deficiency in children with congenital heart disease: a pilot feasibility dose evaluation randomized controlled trial

First Author:

McNally, JD

Journal:

Pilot and Feasibility Studies

Year:

2020

Group:

,

McNally JD, O’Hearn K, Fergusson DA, Lougheed J, Doherty DR, Maharajh G, Weiler H, Jones G, Khamessan A, Redpath S, Geier P, McIntyre L, Lawson ML, Girolamo T & Kusum Menon on behalf of the Canadian Critical Care Trials Group. Prevention of post-cardiac surgery vitamin D deficiency in children with congenital heart disease: a pilot feasibility dose evaluation randomized controlled trial. Pilot and Feasibility Studies volume 6, Article number: 159 (2020)