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TBI international platform trial (BRAINapt)

BRAINapt

Principal Investigator(s):

Alexis Turgeon

BRAINapt

TBI-Prognosis

Principal Investigator(s):

Alexis Turgeon

TBI-QualE

Principal Investigator(s):

Alexis Turgeon

Temperature, Heart and Respiratory Rate Investigation along with Variability Evaluation and Serum Biomarkers Study (THRRIVES)

THRRIVES

Principal Investigator(s):

Andrew Seely, Christopher Bredeson

Enrolment Complete

THRRIVES

Temporal Changes in Thrombin Generation, Protein C Levels and Activated Protein C Generation in Early Septic Shock (PRECISE)

PRECISE

Principal Investigator(s):

Lauralyn McIntyre

PRECISE

The Corticosteroids Early and Extended Domains of the PRACTICAL platform RCT (CORT-E2)

CORT-E2

Principal Investigator(s):

Bram Rochwerg, Lorenzo del Sorbo

In Development

CORT-E2

The dying process in children after withdrawal of life sustaining therapies and organ donation after circulatory death – exploring time to death, auto-resuscitation and impact on families

Principal Investigator(s):

Conall Francoeur

The EXercise and Early Rehabilitation in Critically Ill Children: a Systematic Evaluation (EXERCISE)

EXERCISE

Principal Investigator(s):

Karen Choong

EXERCISE

The frailty, outcomes, recovery and care steps of critically ill patients study (FORECAST)

FORECAST

Principal Investigator(s):

John Muscedere, Sean Bagshaw

Enrolment Complete

FORECAST

The impact of the COVID-19 pandemic on intensive care unit workers: a nationwide survey

Principal Investigator(s):

Sangeeta Mehta

Enrolment Complete

The Larynx, Trachea and Swallowing after prolonged intubation or tracheostomy Study

Principal Investigator(s):

Sangeeta Mehta

The Role of Active Deresuscitation after Resuscitation program (RADAR)

RADAR

Principal Investigator(s):

John Marshall

In Development

RADAR

The safety of discharging children directly home from the pediatric intensive care unit: A Canadian population cohort

Principal Investigator(s):

Nadia Roumeliotis

Therapeutic Plasma Exchange in Septic Shock (Plexsis): A Pilot Study

PLEXSIS

Principal Investigator(s):

Ryan Zarychanski, Emily Rimmer

Enrolling

PLEXSIS

THIRST: Transforming Health Information and Research Synthesis through Technology and Teamwork research program (insightScope)

THIRST

Principal Investigator(s):

Dayre McNally

THIRST

Thresholds for invasive ventilation in hypoxemic respiratory failure

Principal Investigator(s):

Christopher Yarnell

In Development

Timing of Initiation of Renal-Replacement Therapy of Acute Kidney Injury (STARRT-AKI)

STARRT-AKI

Principal Investigator(s):

Sean Bagshaw, Ron Wald

Enrolment Complete

STARRT-AKI

Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shock: A Phase II RCT

Principal Investigator(s):

Lauralyn McIntyre

Understanding and managing the effects of COVID-19 restricted visitation policies on the families and healthcare providers of critically ill patients

Principal Investigator(s):

Kirsten Fiest

Enrolment Complete

Understanding Decision Making in Organ Donation: A National Study

Principal Investigator(s):

Michaël Chassé, Justin Presseau, Kimberly Jordison

Enrolling

Understanding nutrition rehabilitation in survivors of critical illness following hospital discharge

Principal Investigator(s):

Lesley Moisey

Unite-ICU: Engage

Principal Investigator(s):

Dayre McNally

Uric acid elevation in critically ill patients with shock: prevalence and associated organ failure

Principal Investigator(s):

Emmanuel Charbonney