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Canadian Guidelines for the Use of Targeted Temperature Management (Therapeutic Hypothermia) After Cardiac Arrest: A joint statement from The Canadian Association of Emergency Physicians (CAEP), the Canadian Critical Care Society (CCCS), Canadian Neurocritical Care Society (CNCCS), and the Canadian Critical Care Trials Group (CCCTG)

First Author:

Howes D

Journal:

Resuscitation

Year:

2016

Group:

,

Howes D, Gray SH, Brooks SC, Boyd JG, Djogovic D, Golan E, Green RS, Jacka MJ, Sinuff T, Chaplin T, Smith OM, Owen J, Szulewski A, Murphy L, Irvine S, Jichici D, Muscedere J. Canadian Guidelines for the Use of Targeted Temperature Management (Therapeutic Hypothermia) After Cardiac Arrest: A joint statement from The Canadian Association of Emergency Physicians (CAEP), the Canadian Critical Care Society (CCCS), Canadian Neurocritical Care Society (CNCCS), and the Canadian Critical Care Trials Group (CCCTG). Resuscitation. 2016 Jan;98:48-63. PMID: 26417702

Duration of Antimicrobial Treatment for Bacteremia in Canadian Critically Ill Patients.

First Author:

Daneman N

Journal:

Crit Care Med.

Year:

2016

Group:

,

Daneman N, Rishu AH, Xiong W, Bagshaw SM, Dodek P, Hall R, Kumar A, Lamontagne F, Lauzier F, Marshall J, Martin CM, McIntyre L, Muscedere J, Reynolds S, Stelfox HT, Cook DJ, Fowler RA; Canadian Critical Care Trials Group. Duration of Antimicrobial Treatment for Bacteremia in Canadian Critically Ill Patients. Crit Care Med.2016 Feb;44(2):256-64. PMID: 26496448

Stress ulcer prophylaxis in critical illness: a Canadian survey.

First Author:

Shears M

Journal:

Can J Anaesth.

Year:

2016

Group:

,

Shears M, Alhazzani W, Marshall JC, Muscedere J, Hall R, English SW, Dodek PM, Lauzier F, Kanji S, Duffett M, Barletta J, Alshahrani M, Arabi Y, Deane A, Cook DJ. Stress ulcer prophylaxis in critical illness: a Canadian survey. Can J Anaesth. 2016 Feb 24. [Epub ahead of print] PMID: 26911559

The influence of corticosteroid treatment on the outcome of influenza A(H1N1pdm09)-related critical illness

First Author:

Delaney JW

Journal:

Crit Care

Year:

2016

Group:

, ,

Delaney JW, Pinto R, Long J, Lamontagne F, Adhikari NK, Kumar A, Marshall JC, Cook DJ, Jouvet P, Ferguson ND, Griesdale D, Burry LD, Burns KE, Hutchison J, Mehta S, Menon K, Fowler RA; Canadian Critical Care Trials Group H1N1 Collaborative. The influence of corticosteroid treatment on the outcome of influenza A(H1N1pdm09)-related critical illness. Crit Care. 2016 Mar 30;20(1):75. PMID: 27036638

CYCLE pilot: a protocol for a pilot randomised study of early cycle ergometry versus routine physiotherapy in mechanically ventilated patients

First Author:

Kho ME

Journal:

BMJ Open

Year:

2016

Group:

,

Kho, ME,  Molloy,AJ, Clarke, F, Herridge, MS, Koo, KKY, Rudkowski, J, Seely, AJE, Pellizzari, JR, Tarride, JE, Mourtzakis, M, Karachi, T, Cook, DJ, the Canadian Critical Care Trials Group. CYCLE pilot: a protocol for a pilot randomised study of early cycle ergometry versus routine physiotherapy in mechanically ventilated patients. BMJ Open. 2016 Apr 8;6(4):e011659. PMID: 27059469

Steroids in fluid and/or vasoactive infusion dependent pediatric shock: study protocol for a randomized controlled trial.

First Author:

O'Hearn K

Journal:

Trials

Year:

2016

Group:

, ,

O'Hearn K, McNally D, Choong K, Acharya A, Wong HR, Lawson M, Ramsay T, McIntyre L, Gilfoyle E, Tucci M, Wensley D, Gottesman R, Morrison G, Menon K; Canadian Critical Care Trials Group. Steroids in fluid and/or vasoactive infusion dependent pediatric shock: study protocol for a randomized controlled trial. Trials. 2016 May 6;17(1):238. PMID: 27153945

One-Year Outcomes in Caregivers of Critically Ill Patients

First Author:

Cameron JI

Journal:

N Engl J Med

Year:

2016

Group:

,

Cameron JI, Chu LM, Matte A, Tomlinson G, Chan L, Thomas C, Friedrich JO, Mehta S, Lamontagne F, Levasseur M, Ferguson ND, Adhikari NK, Rudkowski JC, Meggison H, Skrobik Y, Flannery J, Bayley M, Batt J, dos Santos C, Abbey SE, Tan A, Lo V, Mathur S, Parotto M, Morris D, Flockhart L, Fan E, Lee CM, Wilcox ME, Ayas N, Choong K, Fowler R, Scales DC, Sinuff T, Cuthbertson BH, Rose L, Robles P, Burns S, Cypel M, Singer L, Chaparro C, Chow CW, Keshavjee S, Brochard L, Hébert P, Slutsky AS, Marshall JC, Cook D, Herridge MS; RECOVER Program Investigators (Phase 1: towards RECOVER); Canadian Critical Care Trials Group. One-Year Outcomes in Caregivers of Critically Ill Patients. N Engl J Med. 2016 May 12;374(19):1831-41. PMID: 27168433

Survey of Sedation and Analgesia Practice Among Canadian Pediatric Critical Care Physicians

First Author:

Garcia Guerra G

Journal:

Pediatr Crit Care Med.

Year:

2016

Group:

, ,

Guerra GG, Joffe AR, Cave D, Duff J, Duncan S, Sheppard C, Tawfik G, Hartling L, Jou H, Vohra S; Sedation Withdrawal and Analgesia Team, and the Canadian Critical Care Trials Group. Survey of Sedation and Analgesia Practice Among Canadian Pediatric Critical Care Physicians. Pediatr Crit Care Med. 2016 Sep;17(9):823-30. PMID: 27467012

Variation in diurnal sedation in mechanically ventilated patients who are managed with a sedation protocol alone or a sedation protocol and daily interruption.

First Author:

Mehta S

Journal:

Crit Care

Year:

2016

Group:

,

Mehta S, Meade M, Burry L, Mallick R, Katsios C, Fergusson D, Dodek P, Burns K, Herridge M, Devlin JW, Tanios M, Fowler R, Jacka M, Skrobik Y, Olafson K, Cook D; SLEAP Investigators and the Canadian Critical Care Trials Group. Variation in diurnal sedation in mechanically ventilated patients who are managed with a sedation protocol alone or a sedation protocol and daily interruption. Crit Care. 2016 Aug 1;20(1):233. PMID: 27480314

TryCYCLE: A Prospective Study of the Safety and Feasibility of Early In-Bed Cycling in Mechanically Ventilated Patients

First Author:

Kho ME

Journal:

PLoS One

Year:

2016

Group:

,

Kho ME, Molloy AJ, Clarke FJ, Ajami D, McCaughan M, Obrovac K, Murphy C, Camposilvan L, Herridge MS, Koo KK, Rudkowski J, Seely AJ, Zanni JM, Mourtzakis M, Piraino T, Cook DJ; Canadian Critical Care Trials Group.TryCYCLE: A Prospective Study of the Safety and Feasibility of Early In-Bed Cycling in Mechanically Ventilated Patients. PLoS One. 2016 Dec 28;11(12). PMID: 28030555

Re-evaluating the Inhibition of Stress Erosions (REVISE): a protocol for pilot randomized controlled trial.

First Author:

Alhazzani W

Journal:

Ann Saudi Med.

Year:

2016

Group:

,

Alhazzani W, Guyatt G, Marshall JC, Hall R, Muscedere J, Lauzier F, Thabane L, Alshahrani M, English SW, Arabi YM, Deane AM, Karachi T, Rochwerg B, Finfer S, Daneman N, Zytaruk N, Heel-Ansdell D, Cook D, Of OB. Re-evaluating the Inhibition of Stress Erosions (REVISE): a protocol for pilot randomized controlled trial. Ann Saudi Med. 2016 Nov-Dec;36(6):427-433. PMID: 27920416

Prevalence, Risk Factors, and Outcomes of Delirium in Mechanically Ventilated Adults.

First Author:

Mehta S

Journal:

Crit Care Med

Year:

2015

Group:

,

Mehta S, Cook D, Devlin JW, Skrobik Y, Meade M, Fergusson D, Herridge M, Steinberg M, Granton J, Ferguson N, Tanios M, Dodek P, Fowler R, Burns K, Jacka M, Olafson K, Mallick R, Reynolds S, Keenan S, Burry L; for the SLEAP Investigators and the Canadian Critical Care Trials Group. Prevalence, Risk Factors, and Outcomes of Delirium in Mechanically Ventilated Adults.Crit Care Med. 2015, 43(3):557-66. PMID: 25493968

Clinician perspectives on protocols designed to minimize sedation.

First Author:

Rose L

Journal:

J Crit Care

Year:

2015

Group:

,

Rose L, Fitzgerald E, Cook D, Kim S, Steinberg M, Devlin JW, Ashley BJ, Dodek P, Smith O, Poretta K, Lee Y, Burns K, Harvey J, Skrobik Y, Fergusson D, Meade M, Kraguljac A, Burry L, Mehta S; SLEAP Investigators and the Canadian Critical Care Trials Group.Clinician perspectives on protocols designed to minimize sedation.J Crit Care. 30(2):348-52. PMID: 25466317

Coenrollment in a Randomized Trial of High-Frequency Oscillation: Prevalence, Patterns, Predictors, and Outcomes.

First Author:

Cook DJ

Journal:

Crit Care Med

Year:

2015

Group:

,

Cook DJ, Ferguson ND, Hand L, Austin P, Zhou Q, Adhikari NK, Danesh V, Arabi Y, Matte AL, Clarke FE, Mehta S, Smith O, Wise MP, Friedrich JO, Keenan SP, Hanna S, Meade MO; for the OSCILLation for ARDS Treated Early Investigators and the Canadian Critical Care Trials Group.Coenrollment in a Randomized Trial of High-Frequency Oscillation: Prevalence, Patterns, Predictors, and Outcomes. Crit Care Med. 2015 Feb;43(2):328-38 PMID: 25393702

Age of Transfused Blood in Critically Ill Adults

First Author:

Lacroix J

Journal:

N Engl J Med

Year:

2015

Group:

, ,

Lacroix, J, Hébert, PC, Fergusson, DA, Tinmouth, A, Cook, DJ, Marshall, JC, Clayton, L, McIntyre, L, Callum, J, Turgeon, AF, Blajchman, MA, Walsh, TS, Stanworth, SJ, Campbell, H, Capellier, G, Tiberghien, P, Bardiaux, L, van de Watering, L, van der Meer, NJ, Sabri, E, Vo, D for the ABLE Investigators and the Canadian Critical Care Trials Group. Age of Transfused Blood in Critically Ill Adults.N Engl J Med. 2015, 372(15):1410-8. PMID: 25776801

Critical Care capacity in Canada: results of a national cross-sectional study.

First Author:

Fowler RA

Journal:

Crit Care

Year:

2015

Group:

, ,

Fowler RA, Abdelmalik P, Wood G, Foster D, Gibney N, Bandrauk N, Turgeon AF, Lamontagne F, Kumar A, Zarychanski R, Green R, Bagshaw SM, Stelfox HT, Foster R, Dodek P, Shaw S, Granton J, Lawless B, Hill A, Rose L, Adhikari NK, Scales DC, Cook DJ, Marshall JC, Martin C, Jouvet P; Canadian Critical Care Trials Group and The Canadian ICU Capacity Group. Critical Care capacity in Canada: results of a national cross-sectional study. Crit Care. 2015 Apr 1;19(1):133. PMID: 25888116

Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE): study protocol for a pilot randomized controlled trial.

First Author:

Daneman N

Journal:

Trials

Year:

2015

Group:

,

Daneman N, Rishu AH, Xiong W, Bagshaw SM, Cook DJ, Dodek P, Hall R, Kumar A, Lamontagne F, Lauzier F, Marshall JC, Martin CM, McIntyre L, Muscedere J, Reynolds S, Stelfox HT, Fowler RA; Canadian Critical Care Trials Group. Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE): study protocol for a pilot randomized controlled trial. Trials. 2015 Apr 18;16(1):173. PMID: 25903783

Intensive versus conventional glucose control in critically ill patients with traumatic brain injury: long-term follow-up of a subgroup of patients from the NICE-SUGAR study

First Author:

NICE-SUGAR Study Investigators

Journal:

Intensive Care Med

Year:

2015

Group:

,

NICE-SUGAR Study Investigators for the Australian and New Zealand Intensive Care Society Clinical Trials Group and the Canadian Critical Care Trials Group. Intensive versus conventional glucose control in critically ill patients with traumatic brain injury: long-term follow-up of a subgroup of patients from the NICE-SUGAR study. Intensive Care Med. 2015 Jun;41(6):1037-47. PMID: 26088909

Recall of ICU Stay in Patients Managed With a Sedation Protocol or a Sedation Protocol With Daily Interruption.

First Author:

Burry L

Journal:

Crit Care Med

Year:

2015

Group:

,

Burry L, Cook D, Herridge M, Devlin JW, Fergusson D, Meade M, Steinberg M, Skrobik Y, Olafson K, Burns K, Dodek P, Granton J, Ferguson N, Jacka M, Tanios M, Fowler R, Reynolds S, Keenan S, Mallick R, Mehta S; SLEAP Investigators and the Canadian Critical Care Trials Group. Recall of ICU Stay in Patients Managed With a Sedation Protocol or a Sedation Protocol With Daily Interruption. Crit Care Med. 2015 Oct;43(10):2180-90. PMID: 26181221

Characteristics and Outcomes of Eligible Non-Enrolled Patients in a Mechanical Ventilation Trial of Acute Respiratory Distress Syndrome.

First Author:

Arabi YM

Journal:

Am J Respir Crit Care Med

Year:

2015

Group:

,

Arabi YM, Cook DJ, Zhou Q, Smith O, Hand L, Turgeon AF, Matte A, Mehta S, Graham R, Brierley K, Adhikari NK, Meade MO, Ferguson ND; Canadian Critical Care Trials Group. Characteristics and Outcomes of Eligible Non-Enrolled Patients in a Mechanical Ventilation Trial of Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2015 Jul 20. [Epub ahead of print] PMID: 26192398

Prevention of vitamin D deficiency in children following cardiac surgery: study protocol for a randomized controlled trial.

First Author:

McNally JD

Journal:

Trials

Year:

2015

Group:

, ,

McNally JD, O'Hearn K, Lawson ML, Maharajh G, Geier P, Weiler H, Redpath S, McIntyre L, Fergusson D, Menon K; Canadian Critical Care Trials Groups. Prevention of vitamin D deficiency in children following cardiac surgery: study protocol for a randomized controlled trial. Trials. 2015 Sep 9;16(1):402. PMID: 26353829

Rapid normalization of vitamin D levels: a meta-analysis.

First Author:

McNally JD

Journal:

Pediatrics

Year:

2015

Group:

,

McNally JD, Iliriani K, Pojsupap S, Sampson M, O'Hearn K, McIntyre L, Fergusson D, Menon K. Rapid normalization of vitamin D levels: a meta-analysis. Pediatrics. 2015 Jan;135(1):e152-66. PMID: 25511115

Non-leg venous thrombi during critical illness: a nested prospective cohort study.

First Author:

Lamontagne F

Journal:

JAMA Intern Med.

Year:

2014

Group:

,

Lamontagne F, Heels-Ansdell D, McIntyre L, Dodek P, Meade M, Skrobik Y, McDonald E, Vallance S, Zytaruk N, Cook D, for the PROTECT Investigators, on behalf of the CCCTG and the ANZICS-CTG.  Non-leg venous thrombi during critical illness: a nested prospective cohort study.  JAMA Intern Med. 2014;174(5):689-96. PMID:24638843

Heparin-induced thrombocytopenia in the critically ill: interpreting the 4Ts test in a randomized trial.

First Author:

Crowther M

Journal:

J Crit Care

Year:

2014

Group:

,

Crowther M, Cook D, Guyatt G, Zytaruk N, McDonald E, Williamson D, Albert M, Dodek P, Finfer S, Vallance S, Heels-Ansdell D, McIntyre L, Mehta S, Lamontagne F, Muscedere J, Jacka M, Lesur O, Kutsiogiannis J, Friedrich J1, Klinger JR, Qushmaq I, Burry L, Khwaja K, Sheppard JA, Warkentin TE; PROTECT collaborators; Canadian Critical Care Trials Group; Australian and New Zealand Intensive Care Society Clinical Trials Group.Heparin-induced thrombocytopenia in the critically ill: interpreting the 4Ts test in a randomized trial. J Crit Care. 2014 Jun;29(3):470.e7-15. PMID:24726205