COVID-19 Network of Clinical Trials Networks

A durable infrastructure for Canadian acute care clinical trials and emergency research response

The COVID-19 Network of Clinical Trials Networks is creating capacity and collaboration to embed research into clinical care and support a learning health system.

Led by the Canadian Critical Care Trials Group (CCCTG), the COVID-19 Network of Clinical Trials Networks (Network of Networks) is a pan-Canadian partnership of over 400 inter-professional members - patient partners, clinical and translational scientists, health care professionals, research coordinators and trainees - at healthcare centres across Canada. As a national collaborative, we are already solidifying a dynamic, responsive, nimble and durable clinical trials network in acute care.

With 15 working groups of leading Canadian experts, the Network of Networks is building on 30 years of collaborations and a history of championing scalable, context-responsive research approaches.

About the Network

In January 2021, with support from the Canadian Institutes of Health Research (CIHR), the Canadian Critical Care Trials Group (CCCTG) established the COVID-19 Network of Clinical Trials Networks comprising ambulatory, acute and critical care, rehabilitation, and long-term follow-up networks and trials.

We have championed scalable, context-responsive research approaches, including the parallel evaluation of multiple therapies using adaptive platform clinical trials into which we have incorporated COVID-19 pandemic-relevant treatment arms and enrolled COVID-19 infected patients in Canada and, with international partner trials groups, around the world.

The COVID-19 Network of Clinical Trials Networks is strengthening, mentoring and supporting a growing system of existing and new trials, networks and partnerships to accelerate research on interventions to combat COVID-19 and create a durable infrastructure for Canadian acute care clinical trials and emergency research response.