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Indigenous-focused Guidance Circle
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As part of the Winnipeg program, CCCTG also hosted its first Indigenous-focused Guidance Circle. Developed and coordinated by Paula Sevestre, Indigenous Engagement and Liaison Manager, this event facilitated open discussions on intensive care, bringing together those who have experienced, or have had a loved one experience the ICU, along with CCCTG members including physicians, care team members, and research coordinators.
Learn more
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The artwork above was created for the CCCTG by Whitney Gould, a Mi'kmaq youth artist from the We'koqma'q First Nation.
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Upcoming Scientific Meetings
CCCTG or CCCTBG membership required
Fall 2024: Virtual, October 2 (Please note change of date. Registration opens next week!)
Winter 2025: Lake Louise, AB - January 20-22
Spring 2025: Magog-Orford, QC - May 26-28
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Focus on Equity, Diversity and Inclusion
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NEW EDI publication
The Diversity of Research Participants in Randomized Controlled Trials and Observational Studies Conducted by the Canadian Critical Care Trials Group. Ann Am Thorac Soc. 2024 Jun 18. doi:10.1513/AnnalsATS.202312-1074OC.
To access the CCCTG’s EDI resources and learn more about the CCCTG’s work to provide informed, authentic leadership for equity, diversity, and inclusion, visit www.ccctg.ca/edi.
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CYCLE, HEMOTION and REVISE trials at Critical Care Reviews 2024
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Three CCCTG trials were among the 11 major trial result presentations at the Critical Care Reviews Meeting 2024. Held annually in Titanic Belfast, Northern Ireland, the Critical Care Reviews Meeting hosts major trial results and reviews the best trials of the year with their chief investigators. The CCCTG is proud of the CYCLE, HEMOTION and REVISE teams on the landmark work that they presented in Belfast.
Learn More
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Early Rehabilitation in Critically ill Children: A Two Center Implementation Study. Pediatr Crit Care Med. 2024 Feb 1;25(2):92-105. doi:10.1097/PCC.0000000000003343. Epub 2024 Jan 19. PMID: 38240534.
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Post-Intensive Care Sequelae in Pediatrics-Results of an Early Rehabilitation Implementation Study. Pediatr Crit Care Med. 2024 Feb 2. doi:10.1097/PCC.0000000000003467. Epub ahead of print. PMID: 38305699.
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Efficacy and Safety of Umbilical Cord-Derived Mesenchymal Stromal Cell Therapy in Preclinical Models of Sepsis: A Systematic Review and Meta-analysis. Stem Cells Transl Med. 2024 Feb 21:szae003. doi:10.1093/stcltm/szae003. Epub ahead of print. PMID: 38381583.
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Patient-important upper gastrointestinal bleeding in the ICU: A mixed-methods study of patient and family perspectives. J Crit Care.2024 Mar 5;81:154761. doi: 10.1016/j.jcrc.2024.154761. Epub ahead of print.PMID: 38447306.
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Administrative data ICD-10 diagnostic codes identifies most lab-confirmed SARS-CoV-2 admissions but misses many discharged from the Emergency Department. Sci Rep. 2024 Mar 12;14(1):6008. doi: 10.1038/s41598-023-49501-7.PMID: 38472258.
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Adjudication of a primary trial outcome: Results of a calibration exercise and protocol for a large international trial. Contemp Clin Trials Commun. 2024 Mar 5;39:101284. doi: 10.1016/j.conctc.2024.101284. PMID:38559746; PMCID: PMC10979133.
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Frailty, Outcomes, Recovery and Care Steps of Critically Ill Patients (FORECAST): a prospective, multi-centre, cohort study. Intensive Care Med. 2024 May 15. doi:10.1007/s00134-024-07404-9. Epub ahead of print. PMID: 38748266.
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Barriers to participation in biosampling-based translational research: A cross-sectional survey of Canadian critical care researchers. PLoS One. 2024 May 17;19(5):e0303304. doi:10.1371/journal.pone.0303304. PMID: 38758919;PMCID: PMC11101101.
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Calcineurin Inhibitor inNEuRoloGically deceased donors to decrease kidney delayed graft function study:study protocol of the CINERGY Pilot randomised controlled trial. BMJ Open. 2024 Jun 13;14(6):e086777. doi:10.1136/bmjopen-2024-086777. PMID: 38871657.
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Liberal or Restrictive Transfusion Strategy in Patients with Traumatic Brain Injury. N Engl J Med. 2024 Jun 13. doi:10.1056/NEJMoa2404360. Epub ahead of print. PMID: 38869931.
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Leveraging a clinical emergency department dataset to estimate two-dose COVID-19 vaccine effectiveness and duration of protection in Canada. Vaccine. 2024 Jun 14:S0264-410X(24)00699-6. doi:10.1016/j.vaccine.2024.06.025. Epub ahead of print. PMID:38879407.
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The response of Canada's clinical health research ecosystem to the COVID-19 pandemic. CMAJ. 2024 Jun 16;196(23):E779-E788. doi:10.1503/cmaj.230760. PMID: 38885975.
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The Diversity of Research Participants in Randomized Controlled Trials and Observational Studies Conducted by the Canadian Critical Care Trials Group. Ann Am Thorac Soc. 2024 Jun 18. doi: 10.1513/AnnalsATS.202312-1074OC. Online ahead of print.
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Microvascular Autoregulation in Skeletal Muscle Using Near-Infrared Spectroscopy and Derivation of Optimal Mean Arterial Pressure in the ICU: Pilot Study and Comparison With Cerebral Near-Infrared Spectroscopy. Crit Care Explor. 2024 Jun 21;6(7):e1111. doi: 10.1097/CCE.0000000000001111. PMID: 38904977.
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What to Measure in Aneurysmal Subarachnoid Haemorrhage Research-An International Delphi Survey. Transl Stroke Res. 2024 Jul 13. doi: 10.1007/s12975-024-01271-8. Epub ahead of print. PMID: 38997598.
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Statistical analysis plan for the SQUEEZE trial: A trial to determine whether septic shock reversal is quicker in pediatric patients randomized to an early goal-directed fluid-sparing strategy vs. usual care (SQUEEZE). Crit Care Resusc. 2024 Jun 22;26(2):123-134. doi: 10.1016/j.ccrj.2024.02.002. PMID: 39072232; PMCID: PMC11282343.
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At the CCCTG 2024 Annual General Meeting, Dr. Karen Burns was presented the Deborah J. Cook Mentorship Award in honour of her tremendous mentorship within the critical care research community and beyond.
Read the announcement
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This section highlights news from members of the CCCTG and the Network of Networks, as well as other related happenings from across the acute and critical care research communities. If we can help disseminate your news or opportunities, please contact us.
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Dr. Sabira Valiani was awarded the Saskatchewan Health Research Foundation Capacity Establishment Grant for her work on Connect-ICU: Improving communication and patient and family-centred care in the ICU with the use of communication technology.
Read the announcement
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CIHR has launched the Fall 2024 Reviewer in Training program for early career researchers. The Reviewer in training program (RiT) offers early career researchers the opportunity to learn about the peer review process at CIHR while gaining valuable experience participating in high-quality reviews. Early career researchers (ECR) can participate in the RiT program in one of two roles: Mentee and ECR Reviewer. Applications will be accepted until August 6th.
See the call for applications to apply.
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Join CanTreatCOVID on October 3 in Toronto for the 2024 Adaptive Platform Trials Scientific Meeting, a unique opportunity to connect with researchers, professionals, trainees, and community members to explore the latest advancements and best practices in adaptive platform trials.
For information and to register, visit the APT Meeting website or contact info@cantreatcovid.org.
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Webinar: Considerations for Effective Integration of Gender and Sex in Research and Clinical Trials
On August 7, join IMPaCT and CANSTAT to explore best practice guidelines for researchers to build more equitable, reflective, and inclusive research and clinical trials with Dr. Natalie Rosen.
Details and Registration: www.impactrials.ca/events/august-webinar
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