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Patient and family engagement in patient care and research in Canadian intensive care units: a national survey

First Author:

Burns KEA

Journal:

Can J Anesth

Year:

2022

Group:

Patient and family engagement in patient care and research in Canadian intensive care units: a national survey. Burns KEA, McDonald E, Debigaré S, Zamir N, Vasquez M, Piche-Ayotte M, Oczkowski S, Canadian Critical Care Trials Group. Can J Anesth/J Can Anesth (2022) 69:1527–1536

Assent in Pediatric Critical Care Research: A Cross-Sectional Stakeholder Survey of Canadian Research Ethics Boards, Research Coordinators, Pediatric Critical Care Researchers, and Nurses

First Author:

O'Hearn K

Journal:

Pediatr Crit Care Med

Year:

2022

Group:

,

O'Hearn K, Cayouette F, Cameron S, Martin DA, Tsampalieros A, Menon K; Canadian Critical Care Trials Group. Assent in Pediatric Critical Care Research: A Cross-Sectional Stakeholder Survey of Canadian Research Ethics Boards, Research Coordinators, Pediatric Critical Care Researchers, and Nurses. Pediatr Crit Care Med. 2022 Oct 13. doi: 10.1097/PCC.0000000000003135. Epub ahead of print. PMID: 36511694.

Derivation and validation of a clinical decision rule to risk-stratify COVID-19 patients discharged from the emergency department: The CCEDRRN COVID discharge score

First Author:

Brooks SC

Journal:

J Am Coll Emerg Physicians Open

Year:

2022

Group:

Brooks SC, Rosychuk RJ, Perry JJ, Morrison LJ, Wiemer H, Fok P, Rowe BH, Daoust R, Vatanpour S, Turner J, Landes M, Ohle R, Hayward J, Scheuermeyer F, Welsford M, Hohl C; Canadian COVID‐19 Rapid Response Network (CCEDRRN) for the Network of Canadian Emergency Researchers (NCER) and the Canadian Critical Care Trials Group (CCCTG). Derivation and validation of a clinical decision rule to risk-stratify COVID-19 patients discharged from the emergency department: The CCEDRRN COVID discharge score. J Am Coll Emerg Physicians Open. 2022 Dec 22;3(6):e12868. doi: 10.1002/emp2.12868. PMID: 36579029; PMCID: PMC9780419.

Impact of restricted visitation policies during COVID-19 on critically ill adults, their families, critical care clinicians, and decision-makers: a qualitative interview study

First Author:

Fiest KM

Journal:

Can J Anaesth

Year:

2022

Group:

Fiest KM, Krewulak KD, Jaworska N, Spence KL, Mizen SJ, Bagshaw SM, Burns KEA, Cook DJ, Fowler RA, Olafson K, Patten SB, Rewa OG, Rochwerg B, Spence S, West A, Stelfox HT, Parsons Leigh J; Canadian Critical Care Trials Group. Impact of restricted visitation policies during COVID-19 on critically ill adults, their families, critical care clinicians, and decision-makers: a qualitative interview study. Can J Anaesth. 2022 Oct;69(10):1248-1259. doi: 10.1007/s12630-022-02301-5. Epub 2022 Aug 17. PMID: 35978160; PMCID: PMC9385091

The CCEDRRN COVID-19 Mortality Score to predict death among nonpalliative patients with COVID-19 presenting to emergency departments: a derivation and validation study

First Author:

Hohl CM

Journal:

CMAJ Open

Year:

2022

Group:

Hohl CM, Rosychuk RJ, Archambault PM, O'Sullivan F, Leeies M, Mercier É, Clark G, Innes GD, Brooks SC, Hayward J, Ho V, Jelic T, Welsford M, Sivilotti MLA, Morrison LJ, Perry JJ; Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN) investigators for the Network of Canadian Emergency Researchers and the Canadian Critical Care Trials Group. The CCEDRRN COVID-19 Mortality Score to predict death among nonpalliative patients with COVID-19 presenting to emergency departments: a derivation and validation study. CMAJ Open. 2022 Feb 8;10(1):E90-E99. doi: 10.9778/cmajo.20210243. PMID: 35135824; PMCID: PMC9259439

Resumption of Cardiac Activity after Withdrawal of Life-Sustaining Measures

First Author:

Dhanani S

Journal:

N Engl J Med

Year:

2021

Group:

,

Dhanani S, Hornby L, van Beinum A, Scales NB, Hogue M, Baker A, Beed S, Boyd JG, Chandler JA, Chassé M, D'Aragon F, Dezfulian C, Doig CJ, Duska F, Friedrich JO, Gardiner D, Gofton T, Harvey D, Herry C, Isac G, Kramer AH, Kutsogiannis DJ, Maslove DM, Meade M, Mehta S, Munshi L, Norton L, Pagliarello G, Ramsay T, Rusinova K, Scales D, Schmidt M, Seely A, Shahin J, Slessarev M, So D, Talbot H, van Mook WNKA, Waldauf P, Weiss M, Wind JT, Shemie SD; Canadian Critical Care Trials Group and the Canadian Donation and Transplantation Research Program.  Resumption of Cardiac Activity after Withdrawal of Life-Sustaining Measures. N Engl J Med. 2021 Jan 28;384(4):345-352. PMID: 33503343

Ventilator Weaning and Discontinuation Practices for Critically Ill Patients

First Author:

Burns KEA

Journal:

JAMA

Year:

2021

Group:

Burns KEA, Rizvi L, Cook DJ, Lebovic G, Dodek P, Villar J, Slutsky AS, Jones A, Kapadia FN, Gattas DJ, Epstein SK, Pelosi P, Kefala K, Meade MO; Canadian Critical Care Trials Group. Ventilator Weaning and Discontinuation Practices for Critically Ill Patients.JAMA. 2021 Mar 23;325(12):1173-1184. PMID: 33755077

An environmental scan of visitation policies in Canadian intensive care units during the first wave of the COVID-19 pandemic

First Author:

Fiest KM

Journal:

Can J Anesth

Year:

2021

Group:

Kirsten M. Fiest, Karla D. Krewulak, Carmen Hiploylee, Sean M. Bagshaw, Karen E. A. Burns, Deborah J. Cook, Robert A. Fowler, Maia S. Kredentser, Daniel J. Niven, Kendiss Olafson, Ken Kuljit, S. Parhar, Scott B. Patten, Alison E. Fox-Robichaud, Oleksa G. Rewa, Bram Rochwerg, Krista L. Spence, Sharon E. Straus, Sean Spence, Andrew West, Henry T. Stelfox, Jeanna Parsons Leigh, for the Canadian Critical Care Trials Group. An environmental scan of visitation policies in Canadian intensive care units during the first wave of the COVID-19 pandemic. Can J Anesth 2021, 8 February.

Characteristics and outcomes of patients with COVID-19 admitted to hospital and intensive care in the first phase of the pandemic in Canada: a national cohort study

First Author:

Murthy, S

Journal:

CMAJ

Year:

2021

Group:

,

S Murthy, PM Archambault, A Atique, FM Carrier, MP Cheng, C Codan, N Daneman, W Dechert, S Douglas, KM Fiest, R Fowler, G Goco, Y Gu, A Guerguerian, R Hall, JM Hsu, A Joffe, P Jouvet, L Kelly, ME Kho, RJ Kruisselbrink, D Kumar, DJ Kutsogiannis, F Lamontagne, TC Lee, KMenon, H O'Grady, K O'Hearn, DH Ovakim, SG Pharand, T Pitre, R Reel, B Reeve, O Rewa, D Richardson, A Rishu, G Sandhu, S Sarfo-Mensah, E Shadowitz, W Sligl, J Solomon, HT Stelfox, A Swanson, H Tessier-Grenier, JLY Tsang, G Wood, SPRINT-SARI Canada Investigators and the Canadian Critical Care Trials Group. Characteristics and outcomes of patients with COVID-19 admitted to hospital and intensive care in the first phase of the pandemic in Canada: a national cohort study. CMAJ 2021 Mar 8;9(1):E181-E188. PMID: 33688026

Importance of nationally coordinated data collection and quality improvement networks

First Author:

Seely AJE

Journal:

Can J Resp, Crit, Sleep Med

Year:

2021

Group:

Seely, Andrew JE and Robert Fowler. Importance of nationally coordinated data collection and quality improvement networks. Canadian Journal of Respiratory, Critical Care and Sleep Medicine. Published online 17 August, 2021.

Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients A Randomized Clinical Trial

First Author:

Johnstone J

Journal:

JAMA

Year:

2021

Group:

Johnstone J, Meade M, Lauzier F, Marshall J, Duan E, Dionne J, Arabi YM, Heels-Ansdell D, Thabane L, Lamarche D; Surette M, Zytaruk N, Mehta S, Dodek P, McIntyre L, English S, Rochwerg B, Karachi T, Henderson S; Wood G, Ovakim D, Herridge M, Granton J, Wilcox E; Goffi A, Stelfox HT, Niven D, Muscedere J, Lamontagne F, D’Aragon F, St.-Arnaud C, Ball I, Nagpal D, Girard M, Aslanian P, Charbonney E, Williamson D, Sligl W, Friedrich J, Adhikari NK, Marquis F, Archambault P, Khwaja K, Kristof A, Kutsogiannis J, Zarychanski R, Paunovic B, Reeve B, Lellouche F, Hosek P, Tsang J, Binnie A, Trop S, Loubani O, Hall R, Cirone R, Reynolds S, Lysecki P, Golan E, Cartin-Ceba R, Taylor R, Cook D; for the Prevention of Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT) Investigators and the Canadian Critical Care Trials Group. Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients: A Randomized Clinical Trial. JAMA 2021; 326(11):1024-1033. doi:10.1001/jama.2021.13355

Consent models in Canadian critical care randomized controlled trials: a scoping review

First Author:

O'Hearn, K

Journal:

Can J Anesth

Year:

2021

Group:

, ,

O’Hearn K, Gibson J, Krewulak K, Porteous R, Saigle V, Sampson M, Tsampalieros A, Barrowman N, Cameron S, and the Canadian Critical Care Trials Group.Consent models in Canadian critical care randomized controlled trials: a scoping review. Can. J Anesthesia; 14 Dec. 2021

Impact of Restricted Visitation Policies During the First Wave of the COVID-19 Pandemic on Communication Between Critically Ill Patients, Families and Clinicians: A Qualitative Interview Study

First Author:

Krewulak K

Journal:

Ann Am Thorac Soc

Year:

2021

Group:

Krewulak KD, Jaworska  N, Spence KL, Mizen SJ, Kupsch  S, Stelfox HT, Parsons Leigh J, Fiest KM, and Canadian Critical Care Trials Group. Impact of Restricted Visitation Policies During the First Wave of the COVID-19 Pandemic on Communication Between Critically Ill Patients, Families and Clinicians: A Qualitative Interview Study. Dec. 16, 2021 DOI: 10.1513/AnnalsATS.202107-877OC PMID: 34914537

CCEDRRN COVID-19 Infection Score (CCIS): development and validation in a Canadian cohort of a clinical risk score to predict SARS-CoV-2 infection in patients presenting to the emergency department with suspected COVID-19

First Author:

McRae AD

Journal:

BMJ Open

Year:

2021

Group:

McRae AD, Hohl CM, Rosychuk R, Vatanpour S, Ghaderi G, Archambault PM, Brooks SC, Cheng I, Davis P, Hayward J, Lang E, Ohle R, Rowe B, Welsford M, Yadav K, Morrison LJ, Perry J, Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN) investigators for the Network of Canadian Emergency Researchers and the Canadian Critical Care Trials Group. CCEDRRN COVID-19 Infection Score (CCIS): development and validation in a Canadian cohort of a clinical risk score to predict SARS-CoV-2 infection in patients presenting to the emergency department with suspected COVID-19 PMID: 34857584  PMCID: PMC8640195  DOI: 10.1136/bmjopen-2021-055832 2021 Dec 2;11 (12):e055832

Clinical evaluation and ancillary testing for the diagnosis of death by neurologic criteria: a cross-sectional survey of Canadian intensivists

First Author:

Chassé M

Journal:

Can J Anaesthesia

Year:

2021

Group:

,

Chassé M, Briard JN, Yu M, Carvalho LP, English SW, D’Aragon F, Lauzier F, Turgeon AF, Dhanani S, McIntyre L, Shemie SD, Knoll G, Fergusson DA, Anthony SJ, Weiss MJ on behalf of the Canadian Critical Care Trials Group. Canadian Journal of Anaesthesia (2021).

Music Use for Sedation in Critically ill Children (MUSiCC trial): a pilot randomized controlled trial

First Author:

Garcia Guerra G

Journal:

Journal of Intensive Care

Year:

2021

Group:

,

Garcia Guerra G, Joffe AR, Sheppard C, Hewson K, Dinu IA, Hajihosseini M, deCaen A, Jou H, Hartling L,  Vohra S & the Canadian Critical Care Trials Group. Music Use for Sedation in Critically ill Children (MUSiCC trial): a pilot randomized controlled trial. Journal of Intensive Care volume 9, Article number: 7 (2021) Published: 12 January 2021

CardiO Cycle: a pilot feasibility study of in-bed cycling in critically ill patients post cardiac surgery

First Author:

Newman ANL

Journal:

Pilot and Feasibility Studies

Year:

2021

Group:

,

Newman ANL, Kho ME, Harris JE, Zamir N, McDonald E, Fox-Robichaud A & Solomon P for the Canadian Critical Care Trials Group. CardiO Cycle: a pilot feasibility study of in-bed cycling in critically ill patients post cardiac surgery. Pilot and Feasibility Studies volume 7, Article number: 13 (2021)  Published: 07 January 2021

Utilization and effect of neuromuscular blockade in a randomized trial of high-frequency oscillation

First Author:

Mehta S

Journal:

J Crit Care

Year:

2021

Group:

Mehta S, Zhou Q, Pinto R, Friedrich JO, Lamontagne F, Ferguson ND, Meade MO, Adhikari NKJ; OSCILLATE Investigators and the Canadian Critical Care Trials Group. Utilization and effect of neuromuscular blockade in a randomized trial of high-frequency oscillation. J Crit Care. 2021 Dec;66:86-92. PMID: 34474282

Feasibility of implementing Extubation Advisor, a clinical decision support tool to improve extubation decision-making in the ICU: a mixed-methods observational study

First Author:

Sarti, AJ

Journal:

BMJ Open

Year:

2021

Group:

Sarti AJ, Zheng K, Herry CL, Sutherland S, Scales NB, Watpool I, Porteous R, Hickey M, Anstee C, Fazekas A, Ramsay T, Burns KE, Seely AJ; Canadian Critical Care Trials Group. Feasibility of implementing Extubation Advisor, a clinical decision support tool to improve extubation decision-making in the ICU: a mixed-methods observational study. BMJ Open. 2021 Aug 12;11(8):e045674. PMID: 34385234

Development of the Canadian COVID-19 Emergency Department Rapid Response Network population-based registry: a methodology study

First Author:

Hohl, CM

Journal:

CMAJ Open

Year:

2021

Group:

Hohl CM, Rosychuk RJ, McRae AD, Brooks SC, Archambault P, Fok PT, Davis P, Jelic T, Turner JP, Rowe BH, Mercier É, Cheng I, Taylor J, Daoust R, Ohle R, Andolfatto G, Atzema C, Hayward J, Khangura JK, Landes M, Lang E, Martin I, Mohindra R, Ting DK, Vaillancourt S, Welsford M, Brar B, Dahn T, Wiemer H, Yadav K, Yan JW, Stachura M, McGavin C, Perry JJ, Morrison LJ; Canadian COVID-19 Emergency Department Rapid Response Network investigators and for the Network of Canadian Emergency Researchers and the Canadian Critical Care Trials Group. Development of the Canadian COVID-19 Emergency Department Rapid Response Network population-based registry: a methodology study. CMAJ Open. 2021 Mar 17;9(1):E261-E270. PMID: 33731427

Surrogate Humane Endpoints in Small Animal Models of Acute Lung Injury: A Modified Delphi Consensus Study of Researchers and Laboratory Animal Veterinarians

First Author:

McGinn, R

Journal:

Crit Care Med

Year:

2021

Group:

McGinn R, Fergusson DA, Stewart DJ, Kristof AS, Barron CC, Thebaud B, McIntyre L, Stacey D, Liepmann M, Dodelet-Devillers A, Zhang H, Renlund R, Lilley E, Downey GP, Brown EG, Côté L, Dos Santos CC, Fox-Robichaud AE, Hussain SNA, Laffey JG, Liu M, MacNeil J, Orlando H, Qureshi ST, Turner PV, Winston BW, Lalu MM; Canadian Critical Care Translational Biology Group.. Surrogate Humane Endpoints in Small Animal Models of Acute Lung Injury: A Modified Delphi Consensus Study of Researchers and Laboratory Animal Veterinarians. Crit Care Med. 2021 Feb 1;49(2):311-323. PMID: 33332817

Dynamic tracking of microvascular hemoglobin content for continuous perfusion monitoring in the intensive care unit: pilot feasibility study

First Author:

Mendelson AA

Journal:

J Clin Monit Comput

Year:

2021

Group:

Mendelson AA, Rajaram A, Bainbridge D, Lawrence KS, Bentall T, Sharpe M, Diop M, Ellis CG; Canadian Critical Care Translational Biology Group. Dynamic tracking of microvascular hemoglobin content for continuous perfusion monitoring in the intensive care unit: pilot feasibility study. J Clin Monit Comput. 2021 Dec;35(6):1453-1465. PMID: 33104968

Moral Distress and Other Wellness Measures in Canadian Critical Care Physicians

First Author:

Dodek PM

Journal:

Ann Am Thorac Soc

Year:

2021

Group:

,

Dodek PM, Cheung EO, Burns KEA, Martin CM, Archambault PM, Lauzier F, Sarti AJ, Mehta S, Fox-Robichaud AE, Seely AJE, Parshuram C, Garros D, Withington DE, Cook DJ, Piquette D, Carnevale FA, Boyd JG, Downar J, Kutsogiannis DJ, Chassé M, Fontela P, Fowler RA, Bagshaw S, Dhanani S, Murthy S, Gehrke P, Fujii T. Moral Distress and Other Wellness Measures in Canadian Critical Care Physicians. Ann Am Thorac Soc. 2021 Aug;18(8):1343-1351. PMID: 33356972

Lessening Organ dysfunction with VITamin C (LOVIT): protocol for a randomized controlled trial

First Author:

Masse MH

Journal:

Trials

Year:

2020

Group:

,

Masse MH, Ménard J, Sprague S, Battista MC, Cook DJ, Guyatt GH, Heyland DK, Kanji S, Pinto R, Day AG, Cohen D, Annane D, McGuinness S, Parke R, Carr A, Arabi Y, Vijayaraghavan BKT, D'Aragon F, Carbonneau É, Maslove D, Hunt M, Rochwerg B, Millen T, Chassé M, Lebrasseur M, Archambault P, Deblois E, Drouin C, Lellouche F, Lizotte P, Watpool I, Porteous R, Clarke F, Marinoff N, Belley-Côté É, Bolduc B, Walker S, Iazzetta J, Adhikari NKJ, Lamontagne F; Canadian Critical Care Trials Group. Lessening Organ dysfunction with VITamin C (LOVIT): protocol for a randomized controlled  trial. Trials. 2020 Jan 8;21(1):42. PMID: 31915072