| | First Author | Journal | Year ▼ | Title | Titre | |
| Fontela, PS | Pediatr Crit Care Med. | 2022 | Clinical Reasoning Behind Antibiotic Use in PICUs: A Qualitative Study | 35013080 | Fontela PS, Gaudreault J, Dagenais M, Noël KC, Déragon A, Lacroix J, Razack S, Rennick J, Quach C, McNally JD, Carnevale FA; Canadian Critical Care Trials Group. Clinical Reasoning Behind Antibiotic Use in PICUs: A Qualitative Study. Pediatr Crit Care Med. 2022 Jan 11. doi: 10.1097/PCC.0000000000002886 |
| Dhanani S | N Engl J Med | 2021 | Resumption of Cardiac Activity after Withdrawal of Life-Sustaining Measures | 33503343 | Dhanani S, Hornby L, van Beinum A, Scales NB, Hogue M, Baker A, Beed S, Boyd JG, Chandler JA, Chassé M, D'Aragon F, Dezfulian C, Doig CJ, Duska F, Friedrich JO, Gardiner D, Gofton T, Harvey D, Herry C, Isac G, Kramer AH, Kutsogiannis DJ, Maslove DM, Meade M, Mehta S, Munshi L, Norton L, Pagliarello G, Ramsay T, Rusinova K, Scales D, Schmidt M, Seely A, Shahin J, Slessarev M, So D, Talbot H, van Mook WNKA, Waldauf P, Weiss M, Wind JT, Shemie SD; Canadian Critical Care Trials Group and the Canadian Donation and Transplantation Research Program. Resumption of Cardiac Activity after Withdrawal of Life-Sustaining Measures. N Engl J Med. 2021 Jan 28;384(4):345-352. PMID: 33503343 |
| Burns KEA | JAMA | 2021 | Ventilator Weaning and Discontinuation Practices for Critically Ill Patients. | 33755077 | Burns KEA, Rizvi L, Cook DJ, Lebovic G, Dodek P, Villar J, Slutsky AS, Jones A, Kapadia FN, Gattas DJ, Epstein SK, Pelosi P, Kefala K, Meade MO; Canadian Critical Care Trials Group. Ventilator Weaning and Discontinuation Practices for Critically Ill Patients.JAMA. 2021 Mar 23;325(12):1173-1184. PMID: 33755077
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| Fiest, K M | Can J Anesth | 2021 | An environmental scan of visitation policies in Canadian intensive care units during the first wave of the COVID-19 pandemic | | Kirsten M. Fiest, Karla D. Krewulak, Carmen Hiploylee, Sean M. Bagshaw, Karen E. A. Burns, Deborah J. Cook, Robert A. Fowler, Maia S. Kredentser, Daniel J. Niven, Kendiss Olafson, Ken Kuljit, S. Parhar, Scott B. Patten, Alison E. Fox-Robichaud, Oleksa G. Rewa, Bram Rochwerg, Krista L. Spence, Sharon E. Straus, Sean Spence, Andrew West, Henry T. Stelfox, Jeanna Parsons Leigh, for the Canadian Critical Care Trials Group. An environmental scan of visitation policies in Canadian intensive care units during the first wave of the COVID-19 pandemic. Can J Anesth 2021, 8 February. See LINK for full paper.
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| Murthy S | CMAJ | 2021 | Characteristics and outcomes of patients with COVID-19 admitted to hospital and intensive care in the first phase of the pandemic in Canada: a national cohort study | 33688026 | S Murthy, PM Archambault, A Atique, FM Carrier, MP Cheng, C Codan, N Daneman, W Dechert, S Douglas, KM Fiest, R Fowler, G Goco, Y Gu, A Guerguerian, R Hall, JM Hsu, A Joffe, P Jouvet, L Kelly, ME Kho, RJ Kruisselbrink, D Kumar, DJ Kutsogiannis, F Lamontagne, TC Lee, KMenon, H O'Grady, K O'Hearn, DH Ovakim, SG Pharand, T Pitre, R Reel, B Reeve, O Rewa, D Richardson, A Rishu, G Sandhu, S Sarfo-Mensah, E Shadowitz, W Sligl, J Solomon, HT Stelfox, A Swanson, H Tessier-Grenier, JLY Tsang, G Wood, SPRINT-SARI Canada Investigators and the Canadian Critical Care Trials Group. Characteristics and outcomes of patients with COVID-19 admitted to hospital and intensive care in the first phase of the pandemic in Canada: a national cohort study. CMAJ 2021 Mar 8;9(1):E181-E188. PMID: 33688026 |
| Seely AJE | Can J Resp, Crit, Sleep Med | 2021 | Importance of nationally coordinated data collection and quality improvement networks | | Seely, Andrew JE and Robert Fowler. Importance of nationally coordinated data collection and quality improvement networks. Canadian Journal of Respiratory, Critical Care and Sleep Medicine. Published online 17 August, 2021. https://doi.org/10.1080/24745332.2021.1946448
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| Johnstone J | JAMA | 2021 | Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients A Randomized Clinical Trial | | Johnstone J, Meade M, Lauzier F, Marshall J, Duan E, Dionne J, Arabi YM, Heels-Ansdell D, Thabane L, Lamarche D; Surette M, Zytaruk N, Mehta S, Dodek P, McIntyre L, English S, Rochwerg B, Karachi T, Henderson S; Wood G, Ovakim D, Herridge M, Granton J, Wilcox E; Goffi A, Stelfox HT, Niven D, Muscedere J, Lamontagne F, D’Aragon F, St.-Arnaud C, Ball I, Nagpal D, Girard M, Aslanian P, Charbonney E, Williamson D, Sligl W, Friedrich J, Adhikari NK, Marquis F, Archambault P, Khwaja K, Kristof A, Kutsogiannis J, Zarychanski R, Paunovic B, Reeve B, Lellouche F, Hosek P, Tsang J, Binnie A, Trop S, Loubani O, Hall R, Cirone R, Reynolds S, Lysecki P, Golan E, Cartin-Ceba R, Taylor R, Cook D; for the Prevention of Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT) Investigators and the Canadian Critical Care Trials Group. Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients: A Randomized Clinical Trial. JAMA 2021; 326(11):1024-1033. doi:10.1001/jama.2021.13355 [Full Article]
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| O'Hearn K | Canadian Journal of Anesthesia | 2021 | Consent models in Canadian critical care randomized controlled trials: a scoping review | | O’Hearn K, Gibson J, Krewulak K, Porteous R, Saigle V, Sampson M, Tsampalieros A, Barrowman N, Cameron S, and the Canadian Critical Care Trials Group.Consent models in Canadian critical care randomized controlled trials: a scoping review. Can. J Anesthesia; 14 Dec. 2021 Learn more |
| Krewulak K | Ann Am Thorac Soc | 2021 | Impact of Restricted Visitation Policies During the First Wave of the COVID-19 Pandemic on Communication Between Critically Ill Patients, Families and Clinicians: A Qualitative Interview Study | 34914537 | Krewulak KD, Jaworska N, Spence KL, Mizen SJ, Kupsch S, Stelfox HT, Parsons Leigh J, Fiest KM, and Canadian Critical Care Trials Group. Impact of Restricted Visitation Policies During the First Wave of the COVID-19 Pandemic on Communication Between Critically Ill Patients, Families and Clinicians: A Qualitative Interview Study. Dec. 16, 2021 DOI: 10.1513/AnnalsATS.202107-877OC PMID: 34914537 |
| McRae AD | BMJ Open | 2021 | CCEDRRN COVID-19 Infection Score (CCIS): development and validation in a Canadian cohort of a clinical risk score to predict SARS-CoV-2 infection in patients presenting to the emergency department with suspected COVID-19 | 34857584 | McRae AD, Hohl CM, Rosychuk R, Vatanpour S, Ghaderi G, Archambault PM, Brooks SC, Cheng I, Davis P, Hayward J, Lang E, Ohle R, Rowe B, Welsford M, Yadav K, Morrison LJ, Perry J, Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN) investigators for the Network of Canadian Emergency Researchers and the Canadian Critical Care Trials Group. CCEDRRN COVID-19 Infection Score (CCIS): development and validation in a Canadian cohort of a clinical risk score to predict SARS-CoV-2 infection in patients presenting to the emergency department with suspected COVID-19 PMID: 34857584 PMCID: PMC8640195 DOI: 10.1136/bmjopen-2021-055832
2021 Dec 2;11 (12):e055832 |
| Chassé M | Can J Anaesthesia | 2021 | Clinical evaluation and ancillary testing for the diagnosis of death by neurologic criteria: a cross-sectional survey of Canadian intensivists | | Chassé M, Briard JN, Yu M, Carvalho LP, English SW, D’Aragon F, Lauzier F, Turgeon AF, Dhanani S, McIntyre L, Shemie SD, Knoll G, Fergusson DA, Anthony SJ, Weiss MJ on behalf of the Canadian Critical Care Trials Group. Canadian Journal of Anaesthesia (2021). Learn More |
| Garcia Guerra G | Journal of Intensive Care | 2021 | Music Use for Sedation in Critically ill Children (MUSiCC trial): a pilot randomized controlled trial | 18359415 | Garcia Guerra G, Joffe AR, Sheppard C, Hewson K, Dinu IA, Hajihosseini M, deCaen A, Jou H, Hartling L, Vohra S & the Canadian Critical Care Trials Group. Music Use for Sedation in Critically ill Children (MUSiCC trial): a pilot randomized controlled trial. Journal of Intensive Care volume 9, Article number: 7 (2021) Published: 12 January 2021 Learn More |
| Newman ANL | Pilot and Feasibility Studies | 2021 | CardiO Cycle: a pilot feasibility study of in-bed cycling in critically ill patients post cardiac surgery | | Newman ANL, Kho ME, Harris JE, Zamir N, McDonald E, Fox-Robichaud A & Solomon P for the Canadian Critical Care Trials Group. CardiO Cycle: a pilot feasibility study of in-bed cycling in critically ill patients post cardiac surgery. Pilot and Feasibility Studies volume 7, Article number: 13 (2021) Published: 07 January 2021 Learn More |
| Mehta, S | Can J Anaesth | 2021 | The impact of the COVID-19 pandemic on intensive care unit workers: a nationwide survey. | 34940952 | Mehta S, Yarnell C, Shah S, Dodek P, Parsons-Leigh J, Maunder R, Kayitesi J, Eta-Ndu C, Priestap F, LeBlanc D, Chen J, Honarmand K; Canadian Critical Care Trials Group. The impact of the COVID-19 pandemic on intensive care unit workers: a nationwide survey.Can J Anaesth. 2021 Dec 23:1-13. PMID: 34940952 |
| Mehta, S | J Crit Care | 2021 | Utilization and effect of neuromuscular blockade in a randomized trial of high-frequency oscillation | 34474282 | Mehta S, Zhou Q, Pinto R, Friedrich JO, Lamontagne F, Ferguson ND, Meade MO, Adhikari NKJ; OSCILLATE Investigators and the Canadian Critical Care Trials Group. Utilization and effect of neuromuscular blockade in a randomized trial of high-frequency oscillation. J Crit Care. 2021 Dec;66:86-92. PMID: 34474282 |
| Mehta, S | Crit Care Med | 2021 | Diversity of Authors of Publications From the Canadian Critical Care Trials Group | 34473658 | Mehta S, Ahluwalia N, Heybati K, Burns KEA, Owais S, Cook DJ; Canadian Critical Care Trials Group. Diversity of Authors of Publications From the Canadian Critical Care Trials Group. Crit Care Med. 2021 Aug 13. PMID: 34473658 |
| Sarti, AJ | BMJ Open | 2021 | Feasibility of implementing Extubation Advisor, a clinical decision support tool to improve extubation decision-making in the ICU: a mixed-methods observational study | 34385234 | Sarti AJ, Zheng K, Herry CL, Sutherland S, Scales NB, Watpool I, Porteous R, Hickey M, Anstee C, Fazekas A, Ramsay T, Burns KE, Seely AJ; Canadian Critical Care Trials Group. Feasibility of implementing Extubation Advisor, a clinical decision support tool to improve extubation decision-making in the ICU: a mixed-methods observational study. BMJ Open. 2021 Aug 12;11(8):e045674. PMID: 34385234 |
| Hohl, CM | CMAJ Open | 2021 | Development of the Canadian COVID-19 Emergency Department Rapid Response Network population-based registry: a methodology study | 33731427 | Hohl CM, Rosychuk RJ, McRae AD, Brooks SC, Archambault P, Fok PT, Davis P, Jelic T, Turner JP, Rowe BH, Mercier É, Cheng I, Taylor J, Daoust R, Ohle R, Andolfatto G, Atzema C, Hayward J, Khangura JK, Landes M, Lang E, Martin I, Mohindra R, Ting DK, Vaillancourt S, Welsford M, Brar B, Dahn T, Wiemer H, Yadav K, Yan JW, Stachura M, McGavin C, Perry JJ, Morrison LJ; Canadian COVID-19 Emergency Department Rapid Response Network investigators and for the Network of Canadian Emergency Researchers and the Canadian Critical Care Trials Group. Development of the Canadian COVID-19 Emergency Department Rapid Response Network population-based registry: a methodology study. CMAJ Open. 2021 Mar 17;9(1):E261-E270. PMID: 33731427 |
| McGinn, R | Crit Care Med | 2021 | Surrogate Humane Endpoints in Small Animal Models of Acute Lung Injury: A Modified Delphi Consensus Study of Researchers and Laboratory Animal Veterinarians | 33332817 | McGinn R, Fergusson DA, Stewart DJ, Kristof AS, Barron CC, Thebaud B, McIntyre L, Stacey D, Liepmann M, Dodelet-Devillers A, Zhang H, Renlund R, Lilley E, Downey GP, Brown EG, Côté L, Dos Santos CC, Fox-Robichaud AE, Hussain SNA, Laffey JG, Liu M, MacNeil J, Orlando H, Qureshi ST, Turner PV, Winston BW, Lalu MM; Canadian Critical Care Translational Biology Group.. Surrogate Humane Endpoints in Small Animal Models of Acute Lung Injury: A Modified Delphi Consensus Study of Researchers and Laboratory Animal Veterinarians. Crit Care Med. 2021 Feb 1;49(2):311-323. PMID: 33332817 |
| Mendelson AA | J Clin Monit Comput | 2021 | Dynamic tracking of microvascular hemoglobin content for continuous perfusion monitoring in the intensive care unit: pilot feasibility study | 33104968 | Mendelson AA, Rajaram A, Bainbridge D, Lawrence KS, Bentall T, Sharpe M, Diop M, Ellis CG; Canadian Critical Care Translational Biology Group. Dynamic tracking of microvascular hemoglobin content for continuous perfusion monitoring in the intensive care unit: pilot feasibility study. J Clin Monit Comput. 2021 Dec;35(6):1453-1465. PMID: 33104968 |
| Masse MH | Trials | 2020 | Lessening Organ dysfunction with VITamin C (LOVIT): protocol for a randomized controlled trial. | 31915072 | Masse MH, Ménard J, Sprague S, Battista MC, Cook DJ, Guyatt GH, Heyland DK, Kanji S, Pinto R, Day AG, Cohen D, Annane D, McGuinness S, Parke R, Carr A, Arabi Y, Vijayaraghavan BKT, D'Aragon F, Carbonneau É, Maslove D, Hunt M, Rochwerg B, Millen T, Chassé M, Lebrasseur M, Archambault P, Deblois E, Drouin C, Lellouche F, Lizotte P, Watpool I, Porteous R, Clarke F, Marinoff N, Belley-Côté É, Bolduc B, Walker S, Iazzetta J, Adhikari NKJ, Lamontagne F; Canadian Critical Care Trials Group. Lessening Organ dysfunction with VITamin C (LOVIT): protocol for a randomized controlled trial. Trials. 2020 Jan 8;21(1):42. PMID: 31915072 |
| Daneman N | Trials | 2020 | A pilot randomized controlled trial of 7 versus 14 days of antibiotic treatment for bloodstream infection on non-intensive care versus intensive care wards. | 31941546 | Daneman N, Rishu AH, Pinto R, Arabi Y, Belley-Cote EP, Cirone R, Downing M, Cook DJ, Hall R, McGuinness S, McIntyre L, Muscedere J, Parke R, Reynolds S, Rogers BA, Shehabi Y, Shin P, Whitlock R, Fowler RA; Canadian Critical Care Trials Group. A pilot randomized controlled trial of 7 versus 14 days of antibiotic treatment for bloodstream infection on non-intensive care versus intensive care wards. Trials. 2020 Jan 15;21(1):92. PMID: 31941546 |
| McDonald E | Am J Crit Care | 2020 | Motivators and Stressors for Canadian Research Coordinators in Critical Care: The MOTIVATE Survey. | 31968081 |
McDonald E, Zytaruk N, Heels-Ansdell D, Smith O, Borges D, Hand L, Clarke F, Nassar A, Bennardo M, Cook D; Canadian Critical Care Research Coordinators’ Group. Motivators and Stressors for Canadian Research Coordinators in Critical Care: The MOTIVATE Survey.Am J Crit Care. 2020 Jan 1;29(1):41-48. PMID: 31968081 |
| Lamontagne F | JAMA | 2020 | Effect of Reduced Exposure to Vasopressors on 90-Day Mortality in Older Critically Ill Patients With Vasodilatory Hypotension: A Randomized Clinical Trial. | 32049269 | Effect of Reduced Exposure to Vasopressors on 90-Day Mortality in Older Critically Ill Patients With Vasodilatory Hypotension: A Randomized Clinical Trial. Lamontagne F1,2, Richards-Belle A3, Thomas K3, Harrison DA3, Sadique MZ4, Grieve RD4, Camsooksai J5, Darnell R3, Gordon AC6,7, Henry D8, Hudson N3, Mason AJ4, Saull M3, Whitman C8, Young JD9, Rowan KM3, Mouncey PR3; 65 trial investigators. JAMA. 2020 Feb 12. doi: 10.1001/jama.2020.0930. [Epub ahead of print]. PMID: 32049269 |
| Garcia Guerra G | Pilot Feasibility Stud. | 2020 | Music Use for Sedation in Critically ill Children (MUSiCC trial): study protocol for a pilot randomized controlled trial. | 32128249 |
Garcia Guerra G, Joffe A, Sheppard C, Hewson K, Dinu IA, de Caen A, Jou H, Hartling L, Vohra S; Canadian Critical Care Trials Group. Music Use for Sedation in Critically ill Children (MUSiCC trial): study protocol for a pilot randomized controlled trial. Pilot Feasibility Stud. 2020 Feb 25;6:31. doi: 10.1186/s40814-020-0563-x. eCollection 2020.. PMID: 32128249 |
| STARRT-AKI Investigators | N Engl J Med. | 2020 | Timing of Initiation of Renal-Replacement Therapy in Acute Kidney Injury | 32668114 | STARRT-AKI Investigators; Canadian Critical Care Trials Group; Australian and New Zealand Intensive Care Society Clinical Trials Group; United Kingdom Critical Care Research Group; Canadian Nephrology Trials Network; Irish Critical Care Trials Group, Bagshaw SM, Wald R, Adhikari NKJ, Bellomo R, da Costa BR, Dreyfuss D, Du B, Gallagher MP, Gaudry S, Hoste EA, Lamontagne F, Joannidis M, Landoni G, Liu KD, McAuley DF, McGuinness SP, Neyra JA, Nichol AD, Ostermann M, Palevsky PM, Pettilä V, Quenot JP, Qiu H, Rochwerg B, Schneider AG, Smith OM, Thomé F, Thorpe KE, Vaara S, Weir M, Wang AY, Young P, Zarbock A.Timing of Initiation of Renal-Replacement Therapy in Acute Kidney Injury. N Engl J Med. 2020 Jul 16;383(3):240-251. |
| Chornenki JN | Can J Anaesth. | 2020 | Data initiatives supporting critical care research and quality improvement in Canada: an environmental scan and narrative review. | 31970619 | Chornenki JN, Liaw P, Bagshaw S, Burns K, Dodek P, English S, Fan E, Ferrari N, Fowler R, Fox-Robichaud A, Garland A, Green R, Hebert P, Kho M, Martin C, Maslove D, McDonald E, Menon K, Murthy S, Muscedere J, Scales D, Stelfox HT, Wang HT, Weiss M; Canadian Critical Care Trials Group (CCCTG) and Canadian Critical Care Translational Biology Group (CCCTBG). Data initiatives supporting critical care research and quality improvement in Canada: an environmental scan and narrative review. Can J Anaesth. 2020 Apr;67(4):475-484. |
| Weiss MJ | Can J Anaesth. | 2020 | Survey of Canadian critical care physicians' knowledge and attitudes towards legislative aspects of the deceased organ donation system. | 32696225 | Weiss MJ, English SW, D'Aragon F, Lauzier F, Turgeon AF, Dhanani S, McIntyre L, Carvalho LP, Yu M, Shemie SD, Knoll G, Fergusson DA, Anthony SJ, Haj-Moustafa A, Hartell D, Mohr J, Chassé M; Canadian Critical Care Trials Group.Survey of Canadian critical care physicians' knowledge and attitudes towards legislative aspects of the deceased organ donation system. Can J Anaesth. 2020 Oct;67(10):1349-1358. |
| Ghandour EK | Patient | 2020 | Adapting two American Decision Aids for Mild Traumatic Brain Injury to the Canadian Context Using the Nominal Group Technique. | 33078377 | Ghandour EK, Lelaidier Hould L, Fortier FA, Gélinas V, Melnick ER, Hess EP, Lang ES, Gravel J, Perry JJ, Le Sage N, Truchon C, LeBlanc A, Dubrovsky AS, Gagnon MP, Ouellet MC, Gagnon I, McKenna S, Légaré F, Sauvé L, van de Belt TH, Kavanagh É, Paquette L, Verrette AC, Plante P, Riopelle RJ, Archambault PM; Canadian Critical Care Trials Group, the Canadian Traumatic Brain Injury Research Consortium and the Network of Canadian Emergency Researchers. Adapting two American Decision Aids for Mild Traumatic Brain Injury to the Canadian Context Using the Nominal Group Technique. Patient. 2020 Oct 20. doi: 10.1007/s40271-020-00459-y. Online ahead of print. |
| Noel KC | Pediatr. Crit Care Med | 2020 | International Survey on Determinants of Antibiotic Duration and Discontinuation in Pediatric Critically Ill Patients | 32639469 | KC Noël, J Papenburg, J Lacroix, C Quach, S O'Donnell, M Gonzales, DF Willson, E Gilfoyle, JD McNally, S Reynolds, Y Kazzaz, A Kawaguchi, M Sato, L Kongkiattikul, S Leteurtre, F Dubos, Y Karaca, F Chiusolo, J Piva, N Dendukuri, PS Fontela, Canadian Critical Care Trials Group (CCCTG) and the Pediatric Lung Injury and Sepsis Investigators (PALISI) Network. International Survey on Determinants of Antibiotic Duration and Discontinuation in Pediatric Critically Ill Patients. Pediatr. Crit Care Med. 2020; Sep;21(9):e696-e706 PMID: 32639469 |
| Williamson, DR | Pilot and Feasibility Studies | 2020 | Agitation, confusion, and aggression in critically ill traumatic brain injury-a pilot cohort study (ACACIA-PILOT) | | Williamson DR, Cherifa SI, Frenette AJ, Mitjans MS, Charbonney E, Cataford G, Williams V, Palacios JL, Burry L, Mehta S, Arbour C & F. Bernard for the Canadian Critical Care Trials Group. Agitation, confusion, and aggression in critically ill traumatic brain injury-a pilot cohort study (ACACIA-PILOT). Pilot and Feasibility Studies volume 6, Article number: 193 (2020) Learn More |
| McNally, JD | Pilot and Feasibility Studies | 2020 | Prevention of post-cardiac surgery vitamin D deficiency in children with congenital heart disease: a pilot feasibility dose evaluation randomized controlled trial | | McNally JD, O’Hearn K, Fergusson DA, Lougheed J, Doherty DR, Maharajh G, Weiler H, Jones G, Khamessan A, Redpath S, Geier P, McIntyre L, Lawson ML, Girolamo T & Kusum Menon on behalf of the Canadian Critical Care Trials Group. Prevention of post-cardiac surgery vitamin D deficiency in children with congenital heart disease: a pilot feasibility dose evaluation randomized controlled trial. Pilot and Feasibility Studies volume 6, Article number: 159 (2020) Learn More
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| D’Aragon F | Can J Anesthesia | 2020 | Variability in deceased donor care in Canada: a report of the Canada-DONATE cohort study | | D’Aragon F, Lamontagne F, Cook D, Dhanani S, Keenan S, Chassé M, English S, Burns KEA, Frenette AJ, Ball I, Boyd JG, Masse M, Breau R, Akhtar A, Kramer A, Rochwerg B, Lauzier F, Kutsogiannis DJ, Ibrahim Q, Hand L, Zhou Q, Meade MO on behalf of the Canadian Critical Care Trials Group and the Canadian Donation and Transplant Research Program. Variability in deceased donor care in Canada: a report of the Canada-DONATE cohort study. Canadian Journal of Anesthesia volume 67, pages 992–1004 (2020) Learn More |
| Kho ME | BMJ Open Resp Res | 2019 | Multicentre pilot randomised clinical trial of early in-bed cycle ergometry with ventilated patients | | Kho ME, Molloy AJ, Clarke FJ, et al. Multicentre pilot randomised clinical trial of early in-bed cycle ergometry with ventilated patients. BMJ Open Resp Res 2019;6:e000383. doi:10.1136/bmjresp-2018-000383. |
| Schlosser K | Crit Care Med | 2019 | Effects of Mesenchymal Stem Cell Treatment on Systemic Cytokine Levels in a Phase 1 Dose Escalation Safety Trial of Septic Shock Patients. | 30720538 | Schlosser K, Wang JP, Dos Santos C, Walley KR, Marshall J, Fergusson DA, Winston BW, Granton J, Watpool I, Stewart DJ, McIntyre LA, Mei SHJ; Canadian Critical Care Trials Group and the Canadian Critical Care Translational Biology Group.Effects of Mesenchymal Stem Cell Treatment on Systemic Cytokine Levels in a Phase 1 Dose Escalation Safety Trial of Septic Shock Patients. Crit Care Med. 2019 Feb 1. doi: 10.1097/CCM.0000000000003657. [Epub ahead of print] PMID: 30720538 |
| Weiss MJ | Pediatr Transplant | 2019 | Development of a multinational registry of pediatric deceased organ donation activity. | 30724003 | Weiss MJ, Domínguez-Gil B, Lahaie N, Nakagawa TA, Scales A, Hornby L, Green M, Gelbart B, Hawkins K, Dhanani S, Dipchand AI, Shemie SD; Canadian Critical Care Trials Group. Development of a multinational registry of pediatric deceased organ donation activity. Pediatr Transplant. 2019 Feb 5:e13345. doi: 10.1111/petr.13345. [Epub ahead of print] PMID: 30724003
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| Bagshaw SM | Clin J Am Soc Nephrol | 2019 | Selection and Receipt of Kidney Replacement in Critically Ill Older Patients with AKI. | 30898872 | Bagshaw SM, Adhikari NKJ, Burns KEA, Friedrich JO, Bouchard J, Lamontagne F, McIntrye LA, Cailhier JF, Dodek P, Stelfox HT, Herridge M, Lapinsky S, Muscedere J, Barton J, Griesdale D, Soth M, Ambosta A, Lebovic G, Wald R; Canadian Critical Care Trials Group.Selection and Receipt of Kidney Replacement in Critically Ill Older Patients with AKI. Clin J Am Soc Nephrol. 2019 Apr 5;14(4):496-505. PMID: 30898872 |
| Ruel-Laliberté J | Can J Anaesth. | 2019 | Effect of age of transfused red blood cells on neurologic outcome following traumatic brain injury (ABLE-tbi Study): a nested study of the Age of Blood Evaluation (ABLE) trial. | 30809776 | Ruel-Laliberté J, Lessard Bonaventure P, Fergusson D, Lacroix J, Zarychanski R, Lauzier F, Tinmouth A, Hébert PC, Green R, Griesdale D, Fowler R, Kramer A, McIntyre LA, Zygun D, Walsh T, Stanworth S, Capellier G, Pili-Floury S, Samain E, Clayton L, Marshall J, Pagliarello G, Sabri E, Neveu X, Léger C, Turgeon AF; Canadian Critical Care Trials Group.Effect of age of transfused red blood cells on neurologic outcome following traumatic brain injury (ABLE-tbi Study): a nested study of the Age of Blood Evaluation (ABLE) trial. Can J Anaesth. 2019 Feb 26. doi: 10.1007/s12630-019-01326-7. [Epub ahead of print] PMID: 30809776 |
| Burns KEA | Crit Care Med. | 2019 | Frequency of Screening for Weaning From Mechanical Ventilation: Two Contemporaneous Proof-of-Principle Randomized Controlled Trials. | 30920411 | Burns KEA, Wong JTY, Dodek P, Cook DJ, Lamontagne F, Cohen A, Mehta S, Kho ME, Hebert PC, Aslanian P, Friedrich JO, Brochard L, Rizvi L, Hand L, Meade MO, Amaral AC, Seely AJ; Canadian Critical Care Trials Group. Frequency of Screening for Weaning From Mechanical Ventilation: Two Contemporaneous Proof-of-Principle Randomized Controlled Trials. Crit Care Med. 2019 Jun;47(6):817-825. PMID: 30920411 |
| Lessard Bonaventure P | Can J Anaesth. | 2019 | Red blood cell transfusion in critically ill patients with traumatic brain injury: an international survey of physicians' attitudes. | 31012052 | Lessard Bonaventure P, Lauzier F, Zarychanski R, Boutin A, Shemilt M, Saxena M, Zolfagari P, Griesdale D, Menon DK, Stanworth S, English S, Chassé M, Fergusson DA, Moore L, Kramer A, Robitaille A, Myburgh J, Cooper J, Hutchinson P, Turgeon AF; Canadian Critical Care Trials Group and the Canadian Traumatic Brain Injury Research Consortium. Red blood cell transfusion in critically ill patients with traumatic brain injury: an international survey of physicians' attitudes. Can J Anaesth. 2019 Sep;66(9):1038-1048. PMID: 31012052 |
| Hamilton M | Chest | 2019 | Determinants of Depressive Symptoms at One Year after Intensive Care Unit Discharge in Survivors of ≥7 Days of Mechanical Ventilation: Results from the RECOVER Program - a Secondary Analysis of a Prospective Multi-Centre Cohort Study. | 31102611 | Hamilton M, Tomlinson G, Chu L, Robles P, Matte A, Burns S, Thomas C, Lamontagne F, Adhikari NK, Ferguson N, Friedrich JO, Rudkowski JC, Skrobik Y, Meggison H, Cameron J, Herridge M; RECOVER Program Investigators and the Canadian Critical Care Trials Group. Determinants of Depressive Symptoms at One Year after Intensive Care Unit Discharge in Survivors of ≥7 Days of Mechanical Ventilation: Results from the RECOVER Program - a Secondary Analysis of a Prospective Multi-Centre Cohort Study. Chest. 2019 May 15. pii: S0012-3692(19)31046-3. doi: 10.1016/j.chest.2019.04.104. [Epub ahead of print]. PMID: 31102611 |
| Tlayjeh H | Respir Care | 2019 | Body Mass Index and Mortality in Subjects With ARDS: Post-hoc Analysis of the OSCILLATE Trial. | 31138733 | Tlayjeh H, Arabi YM, Ferguson ND, Zhou Q, Lamontagne F, Arroliga A, Danesh V, Dominguez-Cherit G, Jimenez E, Mullaly A, Staub B, Meade MO; Canadian Critical Care Trials Group.Body Mass Index and Mortality in Subjects With ARDS: Post-hoc Analysis of the OSCILLATE Trial. Respir Care. 2019 May 28. pii: respcare.06675. doi: 10.4187/respcare.06675. [Epub ahead of print]. PMID: 31138733 |
| Garcia Guerra G | J Crit Care | 2019 | Efficacy of music on sedation, analgesia and delirium in critically ill patients. A systematic review of randomized controlled trials. | 31202161 | Garcia Guerra G, Almeida L, Zorzela L, King-Jones S, Joffe AR, Hartling L, Jou H, Vohra S; Canadian Critical Care Trials Group. Efficacy of music on sedation, analgesia and delirium in critically ill patients. A systematic review of randomized controlled trials. J Crit Care. 2019 Jun 4;53:75-80. PMID: 31202161 |
| Turgeon AF | CMAJ | 2019 | Factors influencing decisions by critical care physicians to withdraw life-sustaining treatments in critically ill adult patients with severe traumatic brain injury. | 31209132 | Turgeon AF, Dorrance K, Archambault P, Lauzier F, Lamontagne F, Zarychanski R, Fowler R, Moore L, Lacroix J, English S, Boutin A, Muscedere J, Burns KEA, Griesdale D, McIntyre LA, Scales D, Bernard F, Yamada J, Squires JE; Canadian Traumatic Brain Injury Research Consortium and the Canadian Critical Care Trials Group. Factors influencing decisions by critical care physicians to withdraw life-sustaining treatments in critically ill adult patients with severe traumatic brain injury. CMAJ. 2019 Jun 17;191(24):E652-E663. PMID: 31209132 |
| Johnstone J | BMJ Open | 2019 | Evaluating probiotics for the prevention of ventilator-associated pneumonia: a randomised placebo-controlled multicentre trial protocol and statistical analysis plan for PROSPECT. | 31227528 | Johnstone J, Heels-Ansdell D, Thabane L, Meade M, Marshall J, Lauzier F, Duan EH, Zytaruk N, Lamarche D, Surette M, Cook DJ; PROSPECT Investigators and the Canadian Critical Care Trials Group.Evaluating probiotics for the prevention of ventilator-associated pneumonia: a randomised placebo-controlled multicentre trial protocol and statistical analysis plan for PROSPECT. BMJ Open. 2019 Jun 20;9(6):e025228. PMID: 31227528 |
| Wood MD | BMJ Open | 2019 | Assessing the relationship between near-infrared spectroscopy-derived regional cerebral oxygenation and neurological dysfunction in critically ill adults: a prospective observational multicentre protocol, on behalf of the Canadian Critical Care Trials Group. | 31243036 | Wood MD, Khan J, Lee KFH, Maslove DM, Muscedere J, Hunt M, Scott SH, Day A, Jacobson JA, Ball I, Slessarev M, O'Regan N, English SW, McCredie V, Chasse M, Griesdale D, Boyd JG. Assessing the relationship between near-infrared spectroscopy-derived regional cerebral oxygenation and neurological dysfunction in critically ill adults: a prospective observational multicentre protocol, on behalf of the Canadian Critical Care Trials Group. BMJ Open. 2019 Jun 25;9(6):e029189. PMID: 31243036 |
| Burns KEA | BMJ Open | 2019 | Variation in the practice of discontinuing mechanical ventilation in critically ill adults: study protocol for an international prospective observational study. | 31501132 | Burns KEA, Rizvi L, Cook DJ, Dodek P, Slutsky AS, Jones A, Villar J, Kapadia FN, Gattas DJ, Epstein SK, Meade MO; Canadian Critical Care Trials Group. Variation in the practice of discontinuing mechanical ventilation in critically ill adults: study protocol for an international prospective observational study. BMJ Open. 2019 Sep 8;9(9):e031775. PMID: 31501132 |
| Burns KEA | Trials | 2019 | Frequency of Screening and SBT Technique Trial - North American Weaning Collaboration (FAST-NAWC): a protocol for a multicenter, factorial randomized trial. | 31604480 | Burns KEA, Rizvi L, Cook DJ, Seely AJE, Rochwerg B, Lamontagne F, Devlin JW, Dodek P, Mayette M, Tanios M, Gouskos A, Kay P, Mitchell S, Kiedrowski KC, Hill NS; Canadian Critical Care Trials Group. Frequency of Screening and SBT Technique Trial - North American Weaning Collaboration (FAST-NAWC): a protocol for a multicenter, factorial randomized trial Trials. 2019 Oct 11;20(1):587. PMID: 31604480 |
| Weiss MJ | Can J Anaesth. | 2019 | Survey of Canadian intensivists on physician non-referral and family override of deceased organ donation. | 31768789 | Weiss MJ, English SW, D'Aragon F, Lauzier F, Turgeon AF, Dhanani S, McIntyre L, Shemie SD, Knoll G, Fergusson DA, Anthony SJ, Haj-Moustafa A, Hartell D, Mohr J, Chassé M; Canadian Critical Care Trials Group. Survey of Canadian intensivists on physician non-referral and family override of deceased organ donation. Can J Anaesth. 2019, 67(3):313-323. PMID: 31768789 |
| Spinella PC | JAMA | 2019 | Effect of Fresh vs Standard-issue Red Blood Cell Transfusions on Multiple Organ Dysfunction Syndrome in Critically Ill Pediatric Patients: A Randomized Clinical Trial. | 31821429 | Spinella PC, Tucci M, Fergusson DA, Lacroix J, Hébert PC, Leteurtre S, Schechtman KB, Doctor A, Berg RA, Bockelmann T, Caro JJ, Chiusolo F, Clayton L, Cholette JM, Guerra GG, Josephson CD, Menon K, Muszynski JA, Nellis ME, Sarpal A, Schafer S, Steiner ME, Turgeon AF; ABC-PICU Investigators, the Canadian Critical Care Trials Group, the Pediatric Acute Lung Injury and Sepsis Investigators Network, the BloodNet Pediatric Critical Care Blood Research Network, and the Groupe Francophone de Réanimation et Urgences P. Effect of Fresh vs Standard-issue Red Blood Cell Transfusions on Multiple Organ Dysfunction Syndrome in Critically Ill Pediatric Patients: A Randomized Clinical Trial. JAMA. 2019 Dec 10;322(22):2179-2190. PMID: 31821429 |
| Crawshaw J | BMJ Open | 2019 | Exploring the experiences and perspectives of substitute decision-makers involved in decisions about deceased organ donation: a qualitative study protocol. | 31874899 | Crawshaw J, Presseau J, van Allen Z, Pinheiro Carvalho L, Jordison K, English S, Fergusson DA, Lauzier F, Turgeon AF, Sarti AJ, Martin C, D'Aragon F, Li AH, Knoll G, Ball I, Brehaut J, Burns KEA, Fortin MC, Weiss M, Meade M, Marsolais P, Shemie S, Zaabat S, Dhanani S, Kitto SC, Chassé M; Canadian Donation and Transplantation Research Program and the Canadian Critical Care Trials Group. Exploring the experiences and perspectives of substitute decision-makers involved in decisions about deceased organ donation: a qualitative study protocol. BMJ Open. 2019 Dec 23;9(12):e034594. PMID: 31874899 |
| McIntyre LA | Am J Respir Crit Care Med. | 2018 | Cellular Immunotherapy for Septic Shock (CISS): A Phase I Clinical Trial. | 28960096 | McIntyre LA, Stewart DJ, Mei SHJ, Courtman D, Watpool I, Granton J, Marshall J, Dos Santos C, Walley KR, Winston BW, Schlosser K, Fergusson DA; Canadian Critical Care Trials Group and the Canadian Critical Care Translational Biology Group. Cellular Immunotherapy for Septic Shock (CISS): A Phase I Clinical Trial. Am J Respir Crit Care Med. 2018 Feb 1;197(3):337-347. PMID: 28960096 |
| Ball IM | Can J Anaesth. | 2018 | The Young Investigator Retreat of the Canadian Critical Care Trials Group: mentorship and self-discovery. | 29150787 | Ball IM, Burry L, Dodek P, Hutchison JS, Leigh JP, McCredie V, Murthy S, Rochwerg B, Cook D; Canadian Critical Care Trials Group and the Canadian Critical Care Translational Biology Group. The Young Investigator Retreat of the Canadian Critical Care Trials Group: mentorship and self-discovery.
Can J Anaesth. 2018 Mar;65(3):239-245. PMID: 29150787 |
| Lai AT | Crit Care Med | 2018 | Chloride and Other Electrolyte Concentrations in Commonly Available 5% Albumin Products. | 29293151 | Lai AT, Zeller MP, Millen T, Kavsak P, Szczeklik W, Elahie A, Alhazzani W, D'Aragon F, Jaeschke R, Lamontagne F, Karachi T, Cook D, Meade M, Rochwerg B; Canadian Critical Care Trials Group. Chloride and Other Electrolyte Concentrations in Commonly Available 5% Albumin Products. Crit Care Med. 2018 Apr;46(4):e326-e329. PMID: 29293151 |
| Garcia Guerra G | J Crit Care | 2018 | Prospective cohort study on noise levels in a pediatric cardiac intensive care unit. | 29274594 | Garcia Guerra G, Joffe AR, Sheppard C, Pugh J, Moez EK, Dinu IA, Jou H, Hartling L, Vohra S; Sedation Withdrawal and Analgesia Team (SWAT); Canadian Critical Care Trials Group (CCCTG). Prospective cohort study on noise levels in a pediatric cardiac intensive care unit.
J Crit Care. 2018 Apr;44:318-322. PMID: 29274594 |
| Parshuram CS | JAMA | 2018 | Effect of a Pediatric Early Warning System on All-Cause Mortality in Hospitalized Pediatric Patients: The EPOCH Randomized Clinical Trial. | 29486493 | Parshuram CS, Dryden-Palmer K, Farrell C, Gottesman R, Gray M, Hutchison JS, Helfaer M, Hunt EA, Joffe AR, Lacroix J, Moga MA, Nadkarni V, Ninis N, Parkin PC, Wensley D, Willan AR, Tomlinson GA; Canadian Critical Care Trials Group and the EPOCH Investigators. Effect of a Pediatric Early Warning System on All-Cause Mortality in Hospitalized Pediatric Patients: The EPOCH Randomized Clinical Trial. JAMA. 2018 Mar 13;319(10):1002-1012. PMID: 29486493 |
| Daneman N | Trials | 2018 | 7 versus 14 days of antibiotic treatment for critically ill patients with bloodstream infection: a pilot randomized clinical trial. | 29452598 | Daneman N, Rishu AH, Pinto R, Aslanian P, Bagshaw SM, Carignan A, Charbonney E, Coburn B, Cook DJ, Detsky ME, Dodek P, Hall R, Kumar A, Lamontagne F, Lauzier F, Marshall JC, Martin CM, McIntyre L, Muscedere J, Reynolds S, Sligl W, Stelfox HT, Wilcox ME, Fowler RA; Canadian Critical Care Trials Group. 7 versus 14 days of antibiotic treatment for critically ill patients with bloodstream infection: a pilot randomized clinical trial. Trials. 2018 Feb 17;19(1):111. doi: 10.1186/s13063-018-2474-1. PMID: 29452598 |
| Shears M | J Crit Care | 2018 | Assessing frailty in the intensive care unit: A reliability and validity study. | 29574340 | Shears M, Takaoka A, Rochwerg B, Bagshaw SM, Johnstone J, Holding A, Tharmalingam S, Millen T, Clarke F, Rockwood K, Li G, Thabane L, Muscedere J, Stelfox HT, Cook DJ; Canadian Critical Care Trials Group. Assessing frailty in the intensive care unit: A reliability and validity study. J Crit Care. 2018 Feb 8;45:197-203. PMID: 29574340 |
| Burns KEA | Am J Respir Crit Care Med. | 2018 | Patient and Family Engagement in the ICU: Untapped Opportunities and Under Recognized Challenges. | 29624408 | Burns KEA, Misak C, Herridge M, Meade MO, Oczkowski S; Patient and Family Partnership Committee of the Canadian Critical Care Trials Group. Patient and Family Engagement in the ICU: Untapped Opportunities and Under Recognized Challenges. Am J Respir Crit Care Med. 2018 Aug 1;198(3):310-319. PMID: 29624408 |
| Alhazzani W | Intensive Care Med. | 2018 | Efficacy and safety of stress ulcer prophylaxis in critically ill patients: a network meta-analysis of randomized trials. | 29199388 | Alhazzani W, Alshamsi F, Belley-Cote E, Heels-Ansdell D, Brignardello-Petersen R, Alquraini M, Perner A, Møller MH, Krag M, Almenawer S, Rochwerg B, Dionne J, Jaeschke R, Alshahrani M, Deane A, Perri D, Thebane L, Al-Omari A, Finfer S, Cook D, Guyatt G. Efficacy and safety of stress ulcer prophylaxis in critically ill patients: a network meta-analysis of randomized trials. Intensive Care Med. 2018 Jan;44(1):1-11. PMID: 29199388 |
| Green RS | Transfusion | 2018 | Age of transfused blood in critically ill adult trauma patients: a prespecified nested analysis of the Age of Blood Evaluation randomized trial. | 29672869 | Green RS, Erdogan M, Lacroix J, Hébert PC, Tinmouth AT, Sabri E, Zhang T, Fergusson DA, Turgeon AF; ABLE Investigators and the Canadian Critical Care Trials Group. Age of transfused blood in critically ill adult trauma patients: a prespecified nested analysis of the Age of Blood Evaluation randomized trial. Transfusion. 2018 Aug;58(8):1846-1854. PMID: 29672869 |
| Gerges PRA | Can J Anaesth | 2018 | Intensity of care and withdrawal of life-sustaining therapies in severe traumatic brain injury patients: a post-hoc analysis of a multicentre retrospective cohort study. | 29949093 | Gerges PRA, Moore L, Léger C, Lauzier F, Shemilt M, Zarychanski R, Scales DC, Burns KEA, Bernard F, Zygun D, Neveu X, Turgeon AF; Canadian Critical Care Trials Group. Intensity of care and withdrawal of life-sustaining therapies in severe traumatic brain injury patients: a post-hoc analysis of a multicentre retrospective cohort study. Can J Anaesth. 2018 Sep;65(9):996-1003. PMID: 29949093 |
| Menon K | J Pediatr Endocrinol Metab | 2018 | Random serum free cortisol and total cortisol measurements in pediatric septic shock. | 29953408 | Menon K, McNally D, Acharya A, O'Hearn K, Choong K, Wong HR, McIntyre L, Lawson M; Canadian Critical Care Trials Group. Random serum free cortisol and total cortisol measurements in pediatric septic shock. J Pediatr Endocrinol Metab. 2018 Jul 26;31(7):757-762. doi: 10.1515/jpem-2018-0027. PMID: 29953408 |
| English SW | Crit Care. | 2018 | Anemia prevalence and incidence and red blood cell transfusion practices in aneurysmal subarachnoid hemorrhage: results of a multicenter cohort study. | 29973245 | English SW, Chassé M, Turgeon AF, Lauzier F, Griesdale D, Garland A, Fergusson D, Zarychanski R, van Walraven C, Montroy K, Ziegler J, Dupont-Chouinard R, Carignan R, Dhaliwal A, Mallick R, Sinclair J, Boutin A, Pagliarello G, Tinmouth A, McIntyre L; Canadian Critical Care Trials Group. Anemia prevalence and incidence and red blood cell transfusion practices in aneurysmal subarachnoid hemorrhage: results of a multicenter cohort study. Crit Care. 2018 Jul 4;22(1):169. PMID: 29973245 |
| D'Aragon F | Can J Anaesth | 2018 | Hamilton-DONATE: a city-wide pilot observational study of the ICU management of deceased organ donors. | 29987806 | D'Aragon F, Cook D, Dhanani S, Ribic C, Burns KEA, Akhtar A, Hand L, Arseneau E, Cupido C, Whittigham H, Healey A, Frenette AJ, Lamontagne F, Meade MO; Canadian Critical Care Trials Group and the Canadian National Transplant Research Program. Hamilton-DONATE: a city-wide pilot observational study of the ICU management of deceased organ donors. Can J Anaesth. 2018 Oct;65(10):1110-1119. PMID: 29987806 |
| Tucci M | Trials. | 2018 | The age of blood in pediatric intensive care units (ABC PICU): study protocol for a randomized controlled trial. | 30055634 | Tucci M, Lacroix J, Fergusson D, Doctor A, Hébert P, Berg RA, Caro J, Josephson CD, Leteurtre S, Menon K, Schechtman K, Steiner ME, Turgeon AF, Clayton L, Bockelmann T, Spinella PC; Canadian Critical Care Trials Group; Pediatric Critical Care Blood Research Network (BloodNet); Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. The age of blood in pediatric intensive care units (ABC PICU): study protocol for a randomized controlled trial. Trials. 2018 Jul 28;19(1):404. PMID: 30055634 |
| Hutchison JS | J Neurotrauma. | 2018 | The Canadian Traumatic Brain Injury Research Consortium: Epitomizing Collaborative Research in Canada. | 30074867 | Hutchison JS, Emery C, Gagnon I, Léger C, Riopelle R, Wellington C, Wilson E, Turgeon AF. The Canadian Traumatic Brain Injury Research Consortium: Epitomizing Collaborative Research in Canada. J Neurotrauma. 2018 Aug 15;35(16):1858-1863. PMID: 30074867 |
| Merritt C | Pediatr Crit Care Med. | 2018 | Beyond Survival: Pediatric Critical Care Interventional Trial Outcome Measure Preferences of Families and Healthcare Professionals. | 29394234 | Merritt C, Menon K, Agus MSD, Choong K, McNally D, O'Hearn K, Watson RS, Wong HR, Duffett M, Wypij D, Zimmerman JJ. Beyond Survival: Pediatric Critical Care Interventional Trial Outcome Measure Preferences of Families and Healthcare Professionals. Pediatr Crit Care Med. 2018 Feb;19(2):e105-e111. PMID: 29394234 |
| Wood MD | J Crit Care | 2018 | Robotic technology provides objective and quantifiable metrics of neurocognitive functioning in survivors of critical illness:A feasibility study. | 30243203 | Wood MD, Maslove DM, Muscedere J, Scott SH, Boyd JG; Canadian Critical Care Trials Group. Robotic technology provides objective and quantifiable metrics of neurocognitive functioning in survivors of critical illness:A feasibility study. J Crit Care. 2018 Sep 12;48:228-236. PMID: 30243203 |
| Lamarche D | Respir Res. | 2018 | Microbial dysbiosis and mortality during mechanical ventilation: a prospective observational study. | 30526610 | Lamarche D, Johnstone J, Zytaruk N, Clarke F, Hand L, Loukov D, Szamosi JC, Rossi L, Schenck LP, Verschoor CP, McDonald E, Meade MO, Marshall JC, Bowdish DME, Karachi T, Heels-Ansdell D, Cook DJ, Surette MG; PROSPECT Investigators; Canadian Critical Care Trials Group; Canadian Critical Care Translational Biology Group. Microbial dysbiosis and mortality during mechanical ventilation: a prospective observational study. Respir Res. 2018 Dec 7;19(1):245. PMID: 30526610 |
| McIntyre L | BMJ Open | 2018 | FLUID trial: a protocol for a hospital-wide open-label cluster crossover pragmatic comparative effectiveness randomised pilot trial. | 30139908 | McIntyre L, Taljaard M, McArdle T, Fox-Robichaud A, English SW, Martin C, Marshall J, Menon K, Muscedere J, Cook DJ, Weijer C, Saginur R, Maybee A, Iyengar A, Forster A, Graham ID, Hawken S, McCartney C, Seely AJ, Stiell IG, Thavorn K, Fergusson DA. FLUID trial: a protocol for a hospital-wide open-label cluster crossover pragmatic comparative effectiveness randomised pilot trial. BMJ Open. 2018 Aug 23;8(8):e022780. PMID: 30139908 |
| Burns KEA | Ann Am Thorac Soc. | 2018 | International Practice Variation in Weaning Critically Ill Adults from Invasive Mechanical Ventilation. | 29509509 | Burns KEA, Raptis S, Nisenbaum R, Rizvi L, Jones A, Bakshi J, Tan W, Meret A, Cook DJ, Lellouche F, Epstein SK, Gattas D, Kapadia FN, Villar J, Brochard L, Lessard MR, Meade MO. International Practice Variation in Weaning Critically Ill Adults from Invasive Mechanical Ventilation. Ann Am Thorac Soc. 2018 Apr;15(4):494-502. PMID: 29509509 |
| Lamontagne F | Intensive Care Med. | 2018 | Pooled analysis of higher versus lower blood pressure targets for vasopressor therapy septic and vasodilatory shock. | 29260272 | Lamontagne F, Day AG, Meade MO, Cook DJ, Guyatt GH, Hylands M, Radermacher P, Chrétien JM, Beaudoin N, Hébert P, D'Aragon F, Meziani F, Asfar P. Pooled analysis of higher versus lower blood pressure targets for vasopressor therapy septic and vasodilatory shock. Intensive Care Med. 2018 Jan;44(1):12-21. PMID: 29260272 |
| Burns KE | Ann Am Thorac Soc. | 2017 | A Multicenter Study of Surrogate Decision-Makers Experiences in Being Approached for Consent for Patient Participation in Research. | 27849142 | Burns KE, Juando Prats C, Maione M, Lanceta M, Zubrinich C Md, Jeffs L PhD, Smith OM; Canadian Critical Care Trials Group. A Multicenter Study of Surrogate Decision-Makers Experiences in Being Approached for Consent for Patient Participation in Research. Ann Am Thorac Soc. 2017 Feb;14(2):238-245. PMID: 27849142 |
| McCredie VA | Ann Am Thorac Soc | 2017 | Airway Management Strategies for Brain-injured Patients Meeting Standard Criteria to Consider Extubation. A Prospective Cohort Study. | 27870576 | McCredie VA, Ferguson ND, Pinto RL, Adhikari NK, Fowler RA, Chapman MG, Burrell A, Baker AJ, Cook DJ, Meade MO, Scales DC; Canadian Critical Care Trials Group.Airway Management Strategies for Brain-injured Patients Meeting Standard Criteria to Consider Extubation. A Prospective Cohort Study.
Ann Am Thorac Soc. 2017 Jan;14(1):85-93. PMID: 27870576 |
| Gilfoyle E | Pediatr Crit Care Med | 2017 | Improved Clinical Performance and Teamwork of Pediatric Interprofessional Resuscitation Teams With a Simulation-Based Educational Intervention. | 28157808 | Gilfoyle E, Koot DA, Annear JC, Bhanji F, Cheng A, Duff JP, Grant VJ, St George-Hyslop CE, Delaloye NJ, Kotsakis A, McCoy CD, Ramsay CE, Weiss MJ, Gottesman RD; Teams4Kids Investigators and the Canadian Critical Care Trials Group. Improved Clinical Performance and Teamwork of Pediatric Interprofessional Resuscitation Teams With a Simulation-Based Educational Intervention. Pediatr Crit Care Med. 2017 Feb;18(2):e62-e69. PMID: 28157808 |
| Rishu AH | J Crit Care | 2017 | Time required to initiate outbreak and pandemic observational research. | 28288355 | Rishu AH, Marinoff N, Julien L, Dumitrascu M, Marten N, Eggertson S, Willems S, Ruddell S, Lane D, Light B, Stelfox HT, Jouvet P, Hall R, Reynolds S, Daneman N, Fowler RA; Canadian Critical Care Trials Group. Time required to initiate outbreak and pandemic observational research. J Crit Care. 2017 Mar 1;40:7-10. PMID: 28288355 |
| Peters MJ | Intensive Care Med | 2017 | The intensive care medicine clinical research agenda in paediatrics. | 28315043 | Peters MJ, Argent A, Festa M, Leteurtre S, Piva J, Thompson A, Willson D, Tissières P, Tucci M, Lacroix J. The intensive care medicine clinical research agenda in paediatrics. Intensive Care Med. 2017 Sep;43(9):1210-1224. PMID: 28315043 |
| Duffett M | Pediatr Crit Care Med. | 2017 | High-Quality Randomized Controlled Trials in Pediatric Critical Care: A Survey of Barriers and Facilitators. | 28328786 | Duffett M, Choong K, Foster J, Meade M, Menon K, Parker M, Cook DJ; Canadian Critical Care Trials Group. High-Quality Randomized Controlled Trials in Pediatric Critical Care: A Survey of Barriers and Facilitators. Pediatr Crit Care Med. 2017 May;18(5):405-413. PMID: 28328786 |
| Menon K | Pediatr Crit Care Med. | 2017 | A Randomized Controlled Trial of Corticosteroids in Pediatric Septic Shock: A Pilot Feasibility Study. | 28406862 | Menon K, McNally D, O'Hearn K, Acharya A, Wong HR, Lawson M, Ramsay T, McIntyre L, Gilfoyle E, Tucci M, Wensley D, Gottesman R, Morrison G, Choong K; Canadian Critical Care Trials Group. A Randomized Controlled Trial of Corticosteroids in Pediatric Septic Shock: A Pilot Feasibility Study.
Pediatr Crit Care Med. 2017 Jun;18(6):505-512. PMID: 28406862 |
| Duffett M | Pilot Feasibility Stud | 2017 | Pediatric intensive care stress ulcer prevention (PIC-UP): a protocol for a pilot randomized trial. | 28533916 | Duffett M, Choong K, Foster J, Gilfoyle E, Lacroix J, Pai N, Thabane L, Cook DJ; Canadian Critical Care Trials Group. Pediatric intensive care stress ulcer prevention (PIC-UP): a protocol for a pilot randomized trial. Pilot Feasibility Stud. 2017 May 19;3:26. PMID: 28533916 |
| Alhazzani W | Crit Care Med. | 2017 | Withholding Pantoprazole for Stress Ulcer Prophylaxis in Critically Ill Patients: A Pilot Randomized Clinical Trial and Meta-Analysis. | 28459708 | Alhazzani W, Guyatt G, Alshahrani M, Deane AM, Marshall JC, Hall R, Muscedere J, English SW, Lauzier F, Thabane L, Arabi YM, Karachi T, Rochwerg B, Finfer S, Daneman N, Alshamsi F, Zytaruk N, Heel-Ansdell D, Cook D; Canadian Critical Care Trials Group.Withholding Pantoprazole for Stress Ulcer Prophylaxis in Critically Ill Patients: A Pilot Randomized Clinical Trial and Meta-Analysis. Crit Care Med. 2017 Jul;45(7):1121-1129. PMID: 28459708 |
| Turgeon AF | BMJ Open. | 2017 | Prognostication in critically ill patients with severe traumatic brain injury: the TBI-Prognosis multicentre feasibility study. | 28416497 | Turgeon AF, Lauzier F, Zarychanski R, Fergusson DA, Léger C, McIntyre LA, Bernard F, Rigamonti A, Burns K, Griesdale DE, Green R, Scales DC, Meade MO, Savard M, Shemilt M, Paquet J, Gariépy JL, Lavoie A, Reddy K, Jichici D, Pagliarello G, Zygun D, Moore L; TBI-Prognosis Study Team and the Canadian Critical Care Trials Group. Prognostication in critically ill patients with severe traumatic brain injury: the TBI-Prognosis multicentre feasibility study. BMJ Open. 2017 Apr 17;7(4):e013779. PMID: 28416497 |
| Fontela PS | Pediatr Crit Care Med. | 2017 | Determinants of Antibiotic Tailoring in Pediatric Intensive Care: A National Survey. | 28661973 | Fontela PS, Quach C, Karim ME, Willson DF, Gilfoyle E, McNally JD, Gonzales M, Papenburg J, Reynolds S, Lacroix J; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network; on behalf of the Canadian Critical Care Trials Group. Determinants of Antibiotic Tailoring in Pediatric Intensive Care: A National Survey. Pediatr Crit Care Med. 2017 Sep;18(9):e395-e405. PMID: 28661973 |
| Wood MD | J Crit Care | 2017 | Low brain tissue oxygenation contributes to the development of delirium in critically ill patients: A prospective observational study. | 28668768 | Wood MD, Maslove DM, Muscedere JG, Day AG, Gordon Boyd J. Cerebral Oxygenation and Neurological Outcomes Following Critical Illness (CONFOCAL) Research Group; Canadian Critical Care Trials Group. Low brain tissue oxygenation contributes to the development of delirium in critically ill patients: A prospective observational study. J Crit Care. 2017 Jun 15;41:289-295. PMID: 28668768 |
| Delaloye NJ | J Patient Saf. | 2017 | Errors During Resuscitation: The Impact of Perceived Authority on Delivery of Care. | 28671912 | Delaloye NJ, Tobler K, OʼNeill T, Kotsakis A, Cooper J, Bank I, Gilfoyle E; Teams4Kids Investigators and the Canadian Critical Care Trials Group. Errors During Resuscitation: The Impact of Perceived Authority on Delivery of Care. J Patient Saf. 2017 Jun 30. doi: 10.1097/PTS.0000000000000359. [Epub ahead of print] PMID: 28671912 |
| DELIRIUM-CS Investigators | CMAJ Open | 2017 | Incidence of delirium after cardiac surgery: protocol for the DELIRIUM-CS Canada cross-sectional cohort study. | 28743102 | DELIRIUM-CS Investigators*; Canadian Cardiovascular Critical Care Society Investigator Group and the Canadian Critical Care Trials Group. Incidence of delirium after cardiac surgery: protocol for the DELIRIUM-CS Canada cross-sectional cohort study. CMAJ Open. 2017 Jul 13;5(3):E565-E569. PMID: 28743102 |
| Rochwerg B | BMJ Open | 2017 | Fluids in Sepsis and Septic Shock (FISSH): protocol for a pilot randomised controlled trial. | 28729329 | Rochwerg B, Millen T, Austin P, Zeller M, D'Aragon F, Jaeschke R, Masse MH, Mehta S, Lamontagne F, Meade M, Guyatt G, Cook DJ; Canadian Critical Care Trials Group. Fluids in Sepsis and Septic Shock (FISSH): protocol for a pilot randomised controlled trial. BMJ Open. 2017 Jul 20;7(7):e017602. PMID: 28729329 |
| Wilkinson AA | BMC Pediatr | 2017 | Brain biomarkers and pre-injury cognition are associated with long-term cognitive outcome in children with traumatic brain injury. | 28738850 | Wilkinson AA, Dennis M, Simic N, Taylor MJ, Morgan BR, Frndova H, Choong K, Campbell C, Fraser D, Anderson V, Guerguerian AM, Schachar R, Hutchison J; Canadian Critical Care Trials Group (CCCTG); Canadian Critical Care Translational Biology Group (CCCTBG). Brain biomarkers and pre-injury cognition are associated with long-term cognitive outcome in children with traumatic brain injury. BMC Pediatr. 2017 Jul 24;17(1):173. PMID: 28738850 |
| Kimawi I | Phys Ther | 2017 | Safety and Feasibility of a Protocolized Approach to In-Bed Cycling Exercise in the Intensive Care Unit: Quality Improvement Project. | 28379571 | Kimawi I, Lamberjack B, Nelliot A, Toonstra AL, Zanni J, Huang M, Mantheiy E, Kho ME, Needham DM.Safety and Feasibility of a Protocolized Approach to In-Bed Cycling Exercise in the Intensive Care Unit: Quality Improvement Project. Phys Ther. 2017 Jun 1;97(6):593-602. PMID: 28379571 |
| Choong K | Pediatr Crit Care Med | 2017 | Early Exercise in Critically Ill Youth and Children, a Preliminary Evaluation: The wEECYCLE Pilot Trial. | 28922268 | Choong K, Awladthani S, Khawaji A, Clark H, Borhan A, Cheng J, Laskey S, Neu C, Sarti A, Thabane L, Timmons BW, Zheng K, Al-Harbi S; Canadian Critical Care Trials Group. Early Exercise in Critically Ill Youth and Children, a Preliminary Evaluation: The wEECYCLE Pilot Trial. Pediatr Crit Care Med. 2017 Nov;18(11):e546-e554. PMID: 28922268 |
| D'Aragon F | BMJ Open | 2017 | Canada-DONATE study protocol: a prospective national observational study of the medical management of deceased organ donors. | 28963316 | D'Aragon F, Dhanani S, Lamontagne F, Cook DJ, Burns K, Akhtar A, Chassé M, Frenette AJ, Keenan S, Lize JF, Kutsogiannis DJ, Kramer A, Hand LE, Arseneau E, Masse MH, Ribic C, Ball I, Baker A, Boyd G, Rochwerg B, Healey A, Hanna S, Guyatt GH, Meade MO; Canadian Critical Care Trials Group and the Canadian National Transplant Research Program. Canada-DONATE study protocol: a prospective national observational study of the medical management of deceased organ donors. BMJ Open. 2017 Sep 28;7(9). PMID: 28963316 |
| Wilkinson AA | Child Neurol Open. | 2017 | Performance Monitoring in Children Following Traumatic Brain Injury Compared to Typically Developing Children. | 29051909 | Wilkinson AA, Dennis M, Taylor MJ, Guerguerian AM, Boutis K, Choong K, Campbell C, Fraser D, Hutchison J, Schachar R; Canadian Critical Care Trials Group (CCCTG). Performance Monitoring in Children Following Traumatic Brain Injury Compared to Typically Developing Children. Child Neurol Open. 2017 Oct 12;4. eCollection 2017 Jan-Dec. PMID: 29051909 |
| Jung JJ | PLoS One. | 2017 | 2009-2010 Influenza A(H1N1)-related critical illness among Aboriginal and non-Aboriginal Canadians. | 29049285 | Jung JJ, Pinto R, Zarychanski R, Cook DJ, Jouvet P, Marshall JC, Kumar A, Long J, Rodin R, Fowler RA; Canadian Critical Care Trials Group H1N1 Collaborative. 2009-2010 Influenza A(H1N1)-related critical illness among Aboriginal and non-Aboriginal Canadians. PLoS One. 2017 Oct 19;12(10):e0184013. eCollection 2017. PMID: 29049285 |
| Lamontagne F | PLoS One | 2017 | Vasopressor Use for Severe Hypotension-A Multicentre Prospective Observational Study. | 28107357 | Lamontagne F, Cook DJ, Meade MO, Seely A, Day AG, Charbonney E, Serri K, Skrobik Y, Hebert P, St-Arnaud C, Quiroz-Martinez H, Mayette M, Heyland DK. Vasopressor Use for Severe Hypotension-A Multicentre Prospective Observational Study. PLoS One. 2017 Jan 20;12(1):e0167840. PMID: 28107357 |
| Hylands M | BMJ Open | 2017 | Vasopressor use following traumatic injury: protocol for a systematic review. | 28246141 | Hylands M, Toma A, Beaudoin N, Frenette AJ, D'Aragon F, Belley-Côté E, Hylander M, Lauzier F, Siemieniuk RA, Charbonney E, Kwong J, Laake JH, Guyatt G, Vandvik PO, Rochwerg B, Green R, Ball I, Scales D, Murthy S, Rizoli S, Asfar P, Lamontagne F. Vasopressor use following traumatic injury: protocol for a systematic review. BMJ Open. 2017 Feb 28;7(2):e014166. PMID: 28246141 |
| Hylands M | PLoS One | 2017 | Vasopressor use following traumatic injury - A single center retrospective study. | 28448605 | Hylands M, Godbout MP, Mayer SK, Fraser WD, Vanasse A, Leclair MA, Turgeon AF, Lauzier F, Charbonney E, Trottier V, Razek TS, Roy A, D'Aragon F, Belley-Côté E, Day AG, Le Guillan S, Sabbagh R, Lamontagne F. Vasopressor use following traumatic injury - A single center retrospective study. PLoS One. 2017 Apr 27;12(4):e0176587. PMID: 28448605 |
| Rochwerg B | Intensive Care Med. | 2017 | CCCS-SSAI WikiRecs clinical practice guideline: vasopressor blood pressure targets in critically ill adults with hypotension and vasopressor use in early traumatic shock. | 28497273 | Rochwerg B, Hylands M, Møller MH, Asfar P, Cohen D, Khadaroo RG, Laake JH, Perner A, Tanguay T, Widder S, Vandvik P, Kristiansen A, Lamontagne F. CCCS-SSAI WikiRecs clinical practice guideline: vasopressor blood pressure targets in critically ill adults with hypotension and vasopressor use in early traumatic shock. Intensive Care Med. 2017 Jul;43(7):1062-1064. PMID: 28497273 |
| Hylands M | Can J Anaesth | 2017 | A systematic review of vasopressor blood pressure targets in critically ill adults with hypotension. | 28497426 | Hylands M, Moller MH, Asfar P, Toma A, Frenette AJ, Beaudoin N, Belley-Côté É, D'Aragon F, Laake JH, Siemieniuk RA, Charbonney E, Lauzier F, Kwong J, Rochwerg B, Vandvik PO, Guyatt G, Lamontagne F.A systematic review of vasopressor blood pressure targets in critically ill adults with hypotension. Can J Anaesth. 2017 Jul;64(7):703-715. PMID: 28497426 |
| Rochwerg B | Can J Anaesth. | 2017 | CCCS-SSAI WikiRecs Clinical Practice Guideline: vasopressor blood pressure targets in critically ill adults with hypotension. | 28497427 | Rochwerg B, Hylands M, Møller M, Asfar P, Cohen D, Khadaroo RG, Laake JH, Perner A, Tanguay T, Widder S, Vandvik P, Kristiansen A, Lamontagne F. CCCS-SSAI WikiRecs Clinical Practice Guideline: vasopressor blood pressure targets in critically ill adults with hypotension. Can J Anaesth. 2017 Jul;64(7):763-765. PMID: 28497427 |
| Rochwerg B | Can J Anaesth. | 2017 | CCCS-SSAI WikiRecs Clinical Practice Guideline: vasopressors in early traumatic shock | 28497428 | Rochwerg B, Hylands M, Møller M, Asfar P, Cohen D, Khadaroo RG, Laake JH, Perner A, Tanguay T, Widder S, Vandvik P, Kristiansen A, Lamontagne F. CCCS-SSAI WikiRecs Clinical Practice Guideline: vasopressors in early traumatic shock. Can J Anaesth. 2017 Jul;64(7):766-768. PMID: 28497428 |
| D'Aragon F | BMJ Open | 2017 | Effect of corticosteroid administration on neurologically deceased organ donors and transplant recipients: a systematic review and meta-analysis. | 28667204 | D'Aragon F, Belley-Cote E, Agarwal A, Frenette AJ, Lamontagne F, Guyatt G, Dhanani S, Meade MO. Effect of corticosteroid administration on neurologically deceased organ donors and transplant recipients: a systematic review and meta-analysis. BMJ Open. 2017 Jun 30;7(6):e014436. PMID: 28667204 |
| McNally D | Pilot Feasibility Stud | 2017 | Study protocol for a phase II dose evaluation randomized controlled trial of cholecalciferol in critically ill children with vitamin D deficiency (VITdAL-PICU study). | 29234503 | McNally D, Amrein K, O'Hearn K, Fergusson D, Geier P, Henderson M, Khamessan A, Lawson ML, McIntyre L, Redpath S, Weiler HA, Menon K; Canadian Critical Care Trials Group.. Study protocol for a phase II dose evaluation randomized controlled trial of cholecalciferol in critically ill children with vitamin D deficiency (VITdAL-PICU study). Pilot Feasibility Stud. 2017 Dec 8;3:70. PMID: 29234503 |
| Duan EH | Ann Am Thorac Soc. | 2017 | Management of Acute Respiratory Distress Syndrome and Refractory Hypoxemia. A Multicenter Observational Study. | 28910146 | Duan EH, Adhikari NKJ, D'Aragon F, Cook DJ, Mehta S, Alhazzani W, Goligher E, Charbonney E, Arabi YM, Karachi T, Turgeon AF, Hand L, Zhou Q, Austin P, Friedrich J, Lamontagne F, Lauzier F, Patel R, Muscedere J, Hall R, Aslanian P, Piraino T, Albert M, Bagshaw SM, Jacka M, Wood G, Henderson W, Dorscheid D, Ferguson ND, Meade MO; Canadian Critical Care Trials Group. Management of Acute Respiratory Distress Syndrome and Refractory Hypoxemia. A Multicenter Observational Study. Ann Am Thorac Soc. 2017 Dec;14(12):1818-1826. PMID: 28910146 |
| Hylands M | BMJ Open | 2017 | Early vasopressor use following traumatic injury: a systematic review. | 29151048 | Hylands M, Toma A, Beaudoin N, Frenette AJ, D'Aragon F, Belley-Côté É, Charbonney E, Møller MH, Laake JH, Vandvik PO, Siemieniuk RA, Rochwerg B, Lauzier F, Green RS, Ball I, Scales D, Murthy S, Kwong JSW, Guyatt G, Rizoli S, Asfar P, Lamontagne F. Early vasopressor use following traumatic injury: a systematic review.
BMJ Open. 2017 Nov 17;7(11):e017559. Review. PMID: 29151048 |
| McNally JD | Crit Care. | 2017 | Vitamin D deficiency in critically ill children: a systematic review and meta-analysis. | 29169388 | McNally JD, Nama N, O'Hearn K, Sampson M, Amrein K, Iliriani K, McIntyre L, Fergusson D, Menon K.
Vitamin D deficiency in critically ill children: a systematic review and meta-analysis. Crit Care. 2017 Nov 23;21(1):287. PMID: 29169388 |
| Menon K | Pediatr Crit Care Med. | 2017 | Primary Outcome Measures in Pediatric Septic Shock Trials: A Systematic Review. | 28099233 | Menon K, McNally JD, Zimmerman JJ, Agus MS, O'Hearn K, Watson RS, Wong HR, Duffett M, Wypij D, Choong K. Primary Outcome Measures in Pediatric Septic Shock Trials: A Systematic Review. Pediatr Crit Care Med. 2017 Mar;18(3):e146-e154. PMID: 28099233 |
| Howes D | Resuscitation | 2016 | Canadian Guidelines for the Use of Targeted Temperature Management (Therapeutic Hypothermia) After Cardiac Arrest: A joint statement from The Canadian Association of Emergency Physicians (CAEP), the Canadian Critical Care Society (CCCS), Canadian Neurocritical Care Society (CNCCS), and the Canadian Critical Care Trials Group (CCCTG) | 26417702 | Howes D, Gray SH, Brooks SC, Boyd JG, Djogovic D, Golan E, Green RS, Jacka MJ, Sinuff T, Chaplin T, Smith OM, Owen J, Szulewski A, Murphy L, Irvine S, Jichici D, Muscedere J. Canadian Guidelines for the Use of Targeted Temperature Management (Therapeutic Hypothermia) After Cardiac Arrest: A joint statement from The Canadian Association of Emergency Physicians (CAEP), the Canadian Critical Care Society (CCCS), Canadian Neurocritical Care Society (CNCCS), and the Canadian Critical Care Trials Group (CCCTG). Resuscitation. 2016 Jan;98:48-63. PMID: 26417702 |
| Daneman N | Crit Care Med. | 2016 | Duration of Antimicrobial Treatment for Bacteremia in Canadian Critically Ill Patients. | 26496448 | Daneman N, Rishu AH, Xiong W, Bagshaw SM, Dodek P, Hall R, Kumar A, Lamontagne F, Lauzier F, Marshall J, Martin CM, McIntyre L, Muscedere J, Reynolds S, Stelfox HT, Cook DJ, Fowler RA; Canadian Critical Care Trials Group. Duration of Antimicrobial Treatment for Bacteremia in Canadian Critically Ill Patients. Crit Care Med.2016 Feb;44(2):256-64. PMID: 26496448 |
| Wind J | J Crit Care | 2016 | Determination of death after circulatory arrest by intensive care physicians: A survey of current practice in the Netherlands. | 26431638 | Wind J, van Mook WN, Dhanani S, van Heurn EW.Determination of death after circulatory arrest by intensive care physicians: A survey of current practice in the Netherlands. J Crit Care. 2016 Feb;31(1):2-6. PMID: 26431638 |
| English SW | J Clin Epidemiol. | 2016 | Enriched Administrative Data Can Be Used To Retrospectively Identify All Known Cases of Primary Subarachnoid Hemorrhage. | 26399902 | English SW, McIntyre L, Fergusson D, Turgeon A, Sun C, Dos Santos MP, Lum C, Sinclair J, Forster A, van Walraven C. Enriched Administrative Data Can Be Used To Retrospectively Identify All Known Cases of Primary Subarachnoid Hemorrhage. J Clin Epidemiol. 2016 Feb;70:146-54. PMID: 26399902 |
| Lee ZY | Nutr Clin Pract. | 2016 | Enhanced Protein-Energy Provision via the Enteral Route in Critically Ill Patients (PEP uP Protocol): A Review of Evidence. | 26385874 | Lee ZY, Barakatun-Nisak MY, Airini IN, Heyland DK. Enhanced Protein-Energy Provision via the Enteral Route in Critically Ill Patients (PEP uP Protocol): A Review of Evidence.Nutr Clin Pract. 2016 Feb;31(1):68-79. PMID: 26385874 |
| Smith OM | Crit Care Med. | 2016 | Nurse Research Experiences and Attitudes Toward the Conduct of Intensive Care Research: A Questionnaire Study | 26672924 | Smith, OM, Dale, C, Mehta, S, Pinto, R, Rose, LN. Nurse Research Experiences and Attitudes Toward the Conduct of Intensive Care Research: A Questionnaire Study. Crit Care Med. 2016 Jan;44(1):153-61. PMID: 26672924 |
| Marshall JC | Crit Care Med. | 2016 | Determinants of Citation Impact in Large Clinical Trials in Critical Care: The Role of Investigator-led Clinical Trials Groups. | 26571189 | Marshall JC, Kwong W, Kommaraju K, Burns KE. Determinants of Citation Impact in Large Clinical Trials in Critical Care: The Role of Investigator-Led Clinical Trials Groups. Crit Care Med. 2016 Apr;44(4):663-70. PMID: 26571189 |
| Boutin A | Transfus Med Rev | 2016 | Red Blood Cell Transfusion in Patients With Traumatic Brain Injury: A Systematic Review and Meta-Analysis. | 26409622 | Boutin A, Chassé M, Shemilt M, Lauzier F, Moore L, Zarychanski R, Griesdale D, Desjardins P, Lacroix J, Fergusson D, Turgeon AF. Red Blood Cell Transfusion in Patients With Traumatic Brain Injury: A Systematic Review and Meta-Analysis. Transfus Med Rev. 2016 Jan;30(1):15-24. PMID: 26409622 |
| Lamontagne F | Intensive Care Med | 2016 | Higher versus lower blood pressure targets for vasopressor therapy in shock: a multicentre pilot randomized controlled trial. | 26891677 | Lamontagne F, Meade MO, Hébert PC, Asfar P, Lauzier F, Seely AJ, Day AG, Mehta S, Muscedere J, Bagshaw SM, Ferguson ND, Cook DJ, Kanji S, Turgeon AF, Herridge MS, Subramanian S, Lacroix J, Adhikari NK, Scales DC, Fox-Robichaud A, Skrobik Y, Whitlock RP, Green RS, Koo KK, Tanguay T, Magder S, Heyland DK; Canadian Critical Care Trials Group. Higher versus lower blood pressure targets for vasopressor therapy in shock: a multicentre pilot randomized controlled trial.
Intensive Care Med. 2016 Feb 18. [Epub ahead of print] PMID: 26891677 |
| Shears M | Can J Anaesth. | 2016 | Stress ulcer prophylaxis in critical illness: a Canadian survey. | 26911559 | Shears M, Alhazzani W, Marshall JC, Muscedere J, Hall R, English SW, Dodek PM, Lauzier F, Kanji S, Duffett M, Barletta J, Alshahrani M, Arabi Y, Deane A, Cook DJ. Stress ulcer prophylaxis in critical illness: a Canadian survey. Can J Anaesth. 2016 Feb 24. [Epub ahead of print] PMID: 26911559 |
| Delaney JW | Crit Care | 2016 | The influence of corticosteroid treatment on the outcome of influenza A(H1N1pdm09)-related critical illness | 27036638 | Delaney JW, Pinto R, Long J, Lamontagne F, Adhikari NK, Kumar A, Marshall JC, Cook DJ, Jouvet P, Ferguson ND, Griesdale D, Burry LD, Burns KE, Hutchison J, Mehta S, Menon K, Fowler RA; Canadian Critical Care Trials Group H1N1 Collaborative. The influence of corticosteroid treatment on the outcome of influenza A(H1N1pdm09)-related critical illness. Crit Care. 2016 Mar 30;20(1):75. PMID: 27036638 |
| Kho ME | BMJ Open | 2016 | CYCLE pilot: a protocol for a pilot randomised study of early cycle ergometry versus routine physiotherapy in mechanically ventilated patients | 27059469 | Kho, ME, Molloy,AJ, Clarke, F, Herridge, MS, Koo, KKY, Rudkowski, J, Seely, AJE, Pellizzari, JR, Tarride, JE, Mourtzakis, M, Karachi, T, Cook, DJ, the Canadian Critical Care Trials Group. CYCLE pilot: a protocol for a pilot randomised study of early cycle ergometry versus routine physiotherapy in mechanically ventilated patients. BMJ Open. 2016 Apr 8;6(4):e011659. PMID: 27059469 |
| Heyland DK | Crit Care Med | 2016 | Predicting Performance Status 1 Year After Critical Illness in Patients 80 Years or Older: Development of a Multivariable Clinical Prediction Model. | 27075141 | Heyland DK, Stelfox HT, Garland A, Cook D, Dodek P, Kutsogiannis J, Jiang X, Turgeon AF, Day AG; Canadian Critical Care Trials Group and the Canadian Researchers at the End of Life Network. Predicting Performance Status 1 Year After Critical Illness in Patients 80 Years or Older: Development of a Multivariable Clinical Prediction Model. Crit Care Med. 2016 Sep;44(9):1718-26. PMID: 27075141 |
| Herridge MS | Intensive Care Med. | 2016 | Recovery and outcomes after the acute respiratory distress syndrome (ARDS) in patients and their family caregivers. | 27025938 | Herridge MS, Moss M, Hough CL, Hopkins RO, Rice TW, Bienvenu OJ, Azoulay E.Recovery and outcomes after the acute respiratory distress syndrome (ARDS) in patients and their family caregivers. Intensive Care Med. 2016 May;42(5):725-38. PMID: 27025938 |
| O'Hearn K | Trials | 2016 | Steroids in fluid and/or vasoactive infusion dependent pediatric shock: study protocol for a randomized controlled trial. | 27153945 | O'Hearn K, McNally D, Choong K, Acharya A, Wong HR, Lawson M, Ramsay T, McIntyre L, Gilfoyle E, Tucci M, Wensley D, Gottesman R, Morrison G, Menon K; Canadian Critical Care Trials Group. Steroids in fluid and/or vasoactive infusion dependent pediatric shock: study protocol for a randomized controlled trial.
Trials. 2016 May 6;17(1):238. PMID: 27153945 |
| Cameron JI | N Engl J Med | 2016 | One-Year Outcomes in Caregivers of Critically Ill Patients | 27168433 | Cameron JI, Chu LM, Matte A, Tomlinson G, Chan L, Thomas C, Friedrich JO, Mehta S, Lamontagne F, Levasseur M, Ferguson ND, Adhikari NK, Rudkowski JC, Meggison H, Skrobik Y, Flannery J, Bayley M, Batt J, dos Santos C, Abbey SE, Tan A, Lo V, Mathur S, Parotto M, Morris D, Flockhart L, Fan E, Lee CM, Wilcox ME, Ayas N, Choong K, Fowler R, Scales DC, Sinuff T, Cuthbertson BH, Rose L, Robles P, Burns S, Cypel M, Singer L, Chaparro C, Chow CW, Keshavjee S, Brochard L, Hébert P, Slutsky AS, Marshall JC, Cook D, Herridge MS; RECOVER Program Investigators (Phase 1: towards RECOVER); Canadian Critical Care Trials Group. One-Year Outcomes in Caregivers of Critically Ill Patients.
N Engl J Med. 2016 May 12;374(19):1831-41. PMID: 27168433 |
| Wilkinson AA | Pediatr Crit Care Med. | 2016 | Serum Biomarkers Help Predict Attention Problems in Critically Ill Children With Traumatic Brain Injury. | 27167007 | Wilkinson AA, Simic N, Frndova H, Taylor MJ, Choong K, Fraser D, Campbell C, Dhanani S, Kuehn S, Beauchamp MH, Farrell C, Anderson V, Guerguerian AM, Dennis M, Schachar R, Hutchison JS; Attention and Traumatic Brain Injury Investigators, the Canadian Critical Care Trials Group, and the Canadian Critical Care Translational Biology Group. Serum Biomarkers Help Predict Attention Problems in Critically Ill Children With Traumatic Brain Injury. Pediatr Crit Care Med. 2016 Jul;17(7):638-48. PMID: 27167007 |
| McIntyre LL | BMJ Open | 2016 | Multicountry survey of emergency and critical care medicine physicians' fluid resuscitation practices for adult patients with early septic shock. | 27388345 | McIntyre L, Rowe BH, Walsh TS, Gray A, Arabi Y, Perner A, Gordon A, Marshall J, Cook D, Fox-Robichaud A, Bagshaw SM, Green R, Schweitzer I, Turgeon A, Zarychanski R, English S, Chassé M, Stiell I, Fergusson D; Canadian Critical Care Trials Group. Multicountry survey of emergency and critical care medicine physicians' fluid resuscitation practices for adult patients with early septic shock. BMJ Open. 2016 Jul 7;6(7). PMID: 27388345 |
| Li G | Respir Res. | 2016 | Risk factors for mortality in patients admitted to intensive care units with pneumonia. | 27401184 | Li G, Cook DJ, Thabane L, Friedrich JO, Crozier TM, Muscedere J, Granton J, Mehta S, Reynolds SC, Lopes RD, Francois L, Freitag AP, Levine MA; PROTECT Investigators for the Canadian Critical Care Trials Group, and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Risk factors for mortality in patients admitted to intensive care units with pneumonia. Respir Res. 2016 Jul 11;17(1):80. PMID: 27401184 |
| Garcia Guerra G | Pediatr Crit Care Med. | 2016 | Survey of Sedation and Analgesia Practice Among Canadian Pediatric Critical Care Physicians | 27467012 | Guerra GG, Joffe AR, Cave D, Duff J, Duncan S, Sheppard C, Tawfik G, Hartling L, Jou H, Vohra S; Sedation Withdrawal and Analgesia Team, and the Canadian Critical Care Trials Group. Survey of Sedation and Analgesia Practice Among Canadian Pediatric Critical Care Physicians. Pediatr Crit Care Med. 2016 Sep;17(9):823-30. PMID: 27467012 |
| Cook DJ | Trials | 2016 | Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial-PROSPECT: a pilot trial. | 27480757 | Cook DJ, Johnstone J, Marshall JC, Lauzier F, Thabane L, Mehta S, Dodek PM, McIntyre L, Pagliarello J, Henderson W, Taylor RW, Cartin-Ceba R, Golan E, Herridge M, Wood G, Ovakim D, Karachi T, Surette MG, Bowdish DM, Lamarche D, Verschoor CP, Duan EH, Heels-Ansdell D, Arabi Y, Meade M; PROSPECT Investigators and the Canadian Critical Care Trials Group. Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial-PROSPECT: a pilot trial. Trials. 2016 Aug 2;17:377. PMID: 27480757 |
| Mehta S | Crit Care | 2016 | Variation in diurnal sedation in mechanically ventilated patients who are managed with a sedation protocol alone or a sedation protocol and daily interruption. | 27480314 | Mehta S, Meade M, Burry L, Mallick R, Katsios C, Fergusson D, Dodek P, Burns K, Herridge M, Devlin JW, Tanios M, Fowler R, Jacka M, Skrobik Y, Olafson K, Cook D; SLEAP Investigators and the Canadian Critical Care Trials Group. Variation in diurnal sedation in mechanically ventilated patients who are managed with a sedation protocol alone or a sedation protocol and daily interruption.
Crit Care. 2016 Aug 1;20(1):233. PMID: 27480314 |
| Jain S | Can Respir J. | 2016 | The Development of a Critical Care Resident Research Curriculum: A Needs Assessment. | 27610029 | Jain S, Menon K, Piquette D, Gottesman R, Hutchison J, Gilfoyle E, Group CC. The Development of a Critical Care Resident Research Curriculum: A Needs Assessment. Can Respir J. 2016; Epub 2016 Aug 16. PMID: 27610029 |
| Parker MJ | Trials | 2016 | A trial to determine whether septic shock-reversal is quicker in pediatric patients randomized to an early goal-directed fluid-sparing strategy versus usual care (SQUEEZE): study protocol for a pilot randomized controlled trial. | 27876084 | Parker MJ, Thabane L, Fox-Robichaud A, Liaw P, Choong K; Canadian Critical Care Trials Group and the Canadian Critical Care Translational Biology Group.A trial to determine whether septic shock-reversal is quicker in pediatric patients randomized to an early goal-directed fluid-sparing strategy versus usual care (SQUEEZE): study protocol for a pilot randomized controlled trial. Trials. 2016 Nov 22;17(1):556. PMID: 27876084 |
| English SW | BMJ Open | 2016 | Aneurysmal SubArachnoid Hemorrhage-Red Blood Cell Transfusion And Outcome (SAHaRA): a pilot randomised controlled trial protocol. | 27927658 | English SW, Fergusson D, Chassé M, Turgeon AF, Lauzier F, Griesdale D, Algird A, Kramer A, Tinmouth A, Lum C, Sinclair J, Marshall S, Dowlatshahi D, Boutin A, Pagliarello G, McIntyre LA; Canadian Critical Care Trials Group. Aneurysmal SubArachnoid Hemorrhage-Red Blood Cell Transfusion And Outcome (SAHaRA): a pilot randomised controlled trial protocol. BMJ Open. 2016 Dec 7;6(12):e012623. PMID: 27927658 |
| Savage RD | PLoS One | 2016 | The Effect of Inadequate Initial Empiric Antimicrobial Treatment on Mortality in Critically Ill Patients with Bloodstream Infections: A Multi-Centre Retrospective Cohort Study. | 27152615 | Savage RD, Fowler RA, Rishu AH, Bagshaw SM, Cook D, Dodek P, Hall R, Kumar A, Lamontagne F, Lauzier F, Marshall J, Martin CM, McIntyre L, Muscedere J, Reynolds S, Stelfox HT, Daneman N. The Effect of Inadequate Initial Empiric Antimicrobial Treatment on Mortality in Critically Ill Patients with Bloodstream Infections: A Multi-Centre Retrospective Cohort Study. PLoS One. 2016 May 6;11(5):e0154944. PMID:27152615 |
| Kho ME | PLoS One | 2016 | Ventilated Patients. | 28030555 | Kho ME, Molloy AJ, Clarke FJ, Ajami D, McCaughan M, Obrovac K, Murphy C, Camposilvan L, Herridge MS, Koo KK, Rudkowski J, Seely AJ, Zanni JM, Mourtzakis M, Piraino T, Cook DJ; Canadian Critical Care Trials Group.TryCYCLE: A Prospective Study of the Safety and Feasibility of Early In-Bed Cycling in Mechanically Ventilated Patients. PLoS One. 2016 Dec 28;11(12). PMID: 28030555 |
| Alhazzani W, | Ann Saudi Med. | 2016 | Re-evaluating the Inhibition of Stress Erosions (REVISE): a protocol for pilot randomized controlled trial. | 27920416 | Alhazzani W, Guyatt G, Marshall JC, Hall R, Muscedere J, Lauzier F, Thabane L, Alshahrani M, English SW, Arabi YM, Deane AM, Karachi T, Rochwerg B, Finfer S, Daneman N, Zytaruk N, Heel-Ansdell D, Cook D, Of OB. Re-evaluating the Inhibition of Stress Erosions (REVISE): a protocol for pilot randomized controlled trial. Ann Saudi Med. 2016 Nov-Dec;36(6):427-433. PMID: 27920416 |
| Herridge MS | Am J Respir Crit Care Med | 2016 | The RECOVER Program: Disability Risk Groups & One Year Outcome after ≥ 7 Days of Mechanical Ventilation. | 26974173 | Herridge MS, Chu LM, Matte A, Tomlinson G, Chan L, Thomas C, Friedrich JO, Mehta S, Lamontagne F, Levasseur M, Ferguson ND, Adhikari NK, Rudkowski JC, Meggison H, Skrobik Y, Flannery J, Bayley M, Batt J, Dos Santos C, Abbey SE, Tan A, Lo V, Mathur S, Parotto M, Morris D, Flockhart L, Fan E, Lee CM, Wilcox ME, Ayas N, Choong K, Fowler R, Scales DC, Sinuff T, Cuthbertson BH, Rose L, Robles P, Burns S, Cypel M, Singer L, Chaparro C, Chow CW, Keshavjee S, Brochard L, Hebert P, Slutsky AS, Marshall JC, Cook D, Cameron JI; RECOVER Program Investigators (Phase 1: towards RECOVER) and the Canadian Critical Care Trials Group. The RECOVER Program: Disability Risk Groups & One Year Outcome after ≥ 7 Days of Mechanical Ventilation. Am J Respir Crit Care Med. 2016 Mar 14. [Epub ahead of print] PMID: 26974173 |
| Koo KK | CMAJ Open | 2016 | Early mobilization of critically ill adults: a survey of knowledge, perceptions and practices of Canadian physicians and physiotherapists. | 27730109 | Koo KK, Choong K, Cook DJ, Herridge M, Newman A, Lo V, Guyatt G, Priestap F, Campbell E, Burns KE, Lamontagne F, Meade MO; Canadian Critical Care Trials Group. Early mobilization of critically ill adults: a survey of knowledge, perceptions and practices of Canadian physicians and physiotherapists. CMAJ Open. 2016 Aug 18;4(3):E448-E454. PMID: 27730109 |
| Fléchelles, O | World J Clin Pediatr | 2016 | Pandemic influenza 2009: Impact of vaccination coverage on critical illness in children, a Canada and France observational study | | Fléchelles, O, Brissaud, O, Fowler, R, Ducruet, T, Jouvet, P. The Pediatric Canadian
Critical Care Trials Group H1N1 Collaborative and Groupe Francophone de Réanimation et Urgences
Pédiatriques. Pandemic influenza 2009: Impact of vaccination coverage on critical illness in children, a Canada and France observational study. World J Clin Pediatr 2016 November 8; 5(4): 374-382 |
| Mehta S | Crit Care Med | 2015 | Prevalence, Risk Factors, and Outcomes of Delirium in Mechanically Ventilated Adults. | 25493968 | Mehta S, Cook D, Devlin JW, Skrobik Y, Meade M, Fergusson D, Herridge M, Steinberg M, Granton J, Ferguson N, Tanios M, Dodek P, Fowler R, Burns K, Jacka M, Olafson K, Mallick R, Reynolds S, Keenan S, Burry L; for the SLEAP Investigators and the Canadian Critical Care Trials Group. Prevalence, Risk Factors, and Outcomes of Delirium in Mechanically Ventilated Adults.Crit Care Med. 2015, 43(3):557-66. PMID: 25493968 |
| Lim W | Crit Care Med | 2015 | Failure of Anticoagulant Thromboprophylaxis: Risk Factors in Medical-Surgical Critically Ill Patients. | 25474533 | Lim W, Meade M, Lauzier F, Zarychanski R, Mehta S, Lamontagne F, Dodek P, McIntyre L, Hall R, Heels-Ansdell D, Fowler R, Pai M, Guyatt G, Crowther MA, Warkentin TE, Devereaux PJ, Walter SD, Muscedere J, Herridge M, Turgeon AF, Geerts W, Finfer S, Jacka M, Berwanger O, Ostermann M, Qushmaq I, Friedrich JO, Cook DJ; for the PROphylaxis for ThromboEmbolism in Critical Care Trial Investigators, the Canadian Critical Care Trials Group, and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Failure of Anticoagulant Thromboprophylaxis: Risk Factors in Medical-Surgical Critically Ill Patients.Crit Care Med. 2015; 43(2):401-10. PMID: 25474533 |
| Downar J | Crit Care Med | 2015 | Nonbeneficial Treatment Canada: Definitions, Causes, and Potential Solutions From the Perspective of Healthcare Practitioners. | 25377017 | Downar J, You JJ, Bagshaw SM, Golan E, Lamontagne F, Burns K, Sridhar SK, Seely A, Meade MO, Fox-Robichaud A, Cook D, Turgeon AF, Dodek P, Xiong W, Fowler R; on behalf of the Canadian Critical Care Trials Group.Nonbeneficial Treatment Canada: Definitions, Causes, and Potential Solutions From the Perspective of Healthcare Practitioners.Crit Care Med. 2015 43(2):270-81. PMID: 25377017 |
| Rose L | J Crit Care | 2015 | Clinician perspectives on protocols designed to minimize sedation. | 25466317 | Rose L, Fitzgerald E, Cook D, Kim S, Steinberg M, Devlin JW, Ashley BJ, Dodek P, Smith O, Poretta K, Lee Y, Burns K, Harvey J, Skrobik Y, Fergusson D, Meade M, Kraguljac A, Burry L, Mehta S; SLEAP Investigators and the Canadian Critical Care Trials Group.Clinician perspectives on protocols designed to minimize sedation.J Crit Care. 30(2):348-52. PMID: 25466317 |
| Cook DJ | Crit Care Med | 2015 | Coenrollment in a Randomized Trial of High-Frequency Oscillation: Prevalence, Patterns, Predictors, and Outcomes. | 25393702 | Cook DJ, Ferguson ND, Hand L, Austin P, Zhou Q, Adhikari NK, Danesh V, Arabi Y, Matte AL, Clarke FE, Mehta S, Smith O, Wise MP, Friedrich JO, Keenan SP, Hanna S, Meade MO; for the OSCILLation for ARDS Treated Early Investigators and the Canadian Critical Care Trials Group.Coenrollment in a Randomized Trial of High-Frequency Oscillation: Prevalence, Patterns, Predictors, and Outcomes. Crit Care Med. 2015 Feb;43(2):328-38 PMID: 25393702
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| Choong K | Pediatr Crit Care Med | 2015 | Functional Recovery Following Critical Illness in Children: The "Wee-Cover" Pilot Study. | 25651047 | Choong K, Al-Harbi S, Siu K, Wong K, Cheng J, Baird B, Pogorzelski D, Timmons B, Gorter JW, Thabane L, Khetani M; on behalf of the Canadian Critical Care Trials Group.Functional Recovery Following Critical Illness in Children: The "Wee-Cover" Pilot Study. Pediatr Crit Care Med. 2015 May;16(4):310-8. PMID: 25651047 |
| Heyland DK | Palliat Med. | 2015 | Admission of the very elderly to the intensive care unit: Family members' perspectives on clinical decision-making from a multicenter cohort study. | 25645668 | Heyland DK, Dodek P, Mehta S, Cook D, Garland A, Stelfox HT, Bagshaw SM, Kutsogiannis DJ, Burns K, Muscedere J, Turgeon AF, Fowler R, Jiang X, Day AG; on behalf of the Canadian Critical Care Trials Group and the Canadian Researchers at the End of Life Network (CARENET).Admission of the very elderly to the intensive care unit: Family members' perspectives on clinical decision-making from a multicenter cohort study. Palliat Med. 2015 Apr;29(4):324-35. PMID: 25645668 |
| Burns KE | Intensive Care Med | 2015 | Is There a Role for Physician Involvement in Introducing Research to Surrogate Decision Makers in the Intensive Care Unit? (The Approach Trial: A Mixed Methods Study) | 25491659 | Burns KEA, Rizvi L, Smith O, Lee Y, Lee J, Wang M, Brown M, Parker M, Premji A, Leung D, Hammond Mobilio M, Gotlib-Conn L, Nisenbaum R, Santos M, Li Y, Mehta S. Is There a Role for Physician Involvement in Introducing Research to Surrogate Decision Makers in the Intensive Care Unit? (The Approach Trial: A Mixed Methods Study) Intensive Care Med 2015;41:58-67. PMID: 25491659 |
| Stelfox H | Chest | 2015 | A Scoping Review of Patient Discharge from Intensive Care: Opportunities and Tools to Improve Care | 25210942 | Stelfox H, Lane D, Boyd J, Taylor S, Perrier L, Straus S, Zygun D, Zuege D. A Scoping Review of Patient Discharge from Intensive Care: Opportunities and Tools to Improve Care. Chest. 2015;147(2):317-27. PMID: 25210942 |
| Li P | Can Respir J. | 2015 | Stakeholder Views regarding Patient Discharge from Intensive Care: Suboptimal Quality and Opportunities for Improvement. | 25522304 | Li P, Boyd JM, Ghali WA, Stelfox HT. Stakeholder Views regarding Patient Discharge from Intensive Care: Suboptimal Quality and Opportunities for Improvement. Can Respir J. 2015, 22(2):115-4. PMID: 25522304 |
| Archambault P | JMIR Res Protoc | 2015 | Implementation and Evaluation of a Wiki Involving Multiple Stakeholders Including Patients in the Promotion of Best Practices in Trauma Care:The WikiTrauma Interrupted Time Series Protocol. | | Archambault PM, Turgeon AF, Witteman HO, Lauzier F, Moore L, Lamontagne F, Horsley T, Gagnon M-P, Droit A, Weiss M, Tremblay S, Lachaine J, Le Sage N, Émond M, Berthelot S, Plaisance A, Lapointe J, Razek T, van de Belt TH, Brand K, Bérubé M, Clément J, Grajales FJ, Eysenbach G, Kuziemsky G, Friedman D, Lang E, Muscedere J, Rizoli S, Roberts DJ, Scales DC, Sinuff T, Stelfox HT, Gagnon I, Chabot C, Grenier R, Légaré F, Canadian Critical Care Trials Group. Implementation and Evaluation of a Wiki Involving Multiple Stakeholders Including Patients in the Promotion of Best Practices in Trauma Care:The WikiTrauma Interrupted Time Series Protocol. JMIR Res Protoc 2015,4(1): e21p.2.
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| Zarychanski R | Crit Care Med | 2015 | The efficacy and safety of heparin in patients with sepsis: A systematic review and meta-analysis. | 25493972 | Zarychanski R, Abou-Setta AM, Kanji S, Turgeon AF, Kumar A, Houston DS, Rimmer E, Houston BL, McIntyre L, Fox-Robichaud AE, Hébert P, Cook DJ, Fergusson DA, for the Canadian Critical Care Trials Group. The efficacy and safety of heparin in patients with sepsis: A systematic review and meta-analysis. Critical Care Medicine. 2015;43(3):511-8. PMID:25493972 |
| Czerwonka AI | J Crit Care | 2015 | Changing support needs of survivors of complex critical illness and their family caregivers across the care continuum: A qualitative pilot study of Towards RECOVER | 25466314 | Czerwonka AI, Herridge MS, Chan L, Chu LM, Matte A, Cameron JI. Changing support needs of survivors of complex critical illness and their family caregivers across the care continuum: A qualitative pilot study of Towards RECOVER. J Crit Care. 2015;30(2):242-9. PMID: 25466314
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| Lacroix J | N Engl J Med | 2015 | Age of Transfused Blood in Critically Ill Adults | 25776801 | Lacroix, J, Hébert, PC, Fergusson, DA, Tinmouth, A, Cook, DJ, Marshall, JC, Clayton, L, McIntyre, L, Callum, J, Turgeon, AF, Blajchman, MA, Walsh, TS, Stanworth, SJ, Campbell, H, Capellier, G, Tiberghien, P, Bardiaux, L, van de Watering, L, van der Meer, NJ, Sabri, E, Vo, D for the ABLE Investigators and the Canadian Critical Care Trials Group. Age of Transfused Blood in Critically Ill Adults.N Engl J Med. 2015, 372(15):1410-8. PMID: 25776801 |
| Parshuram CS | CMAJ | 2015 | Patient safety, resident well-being and continuity of care with different resident duty schedules in the intensive care unit: a randomized trial. | 25667258 | Parshuram CS, Amaral AC, Ferguson ND, Baker GR, Etchells EE, Flintoft V, Granton J, Lingard L, Kirpalani H, Mehta S, Moldofsky H, Scales DC, Stewart TE, Willan AR, Friedrich JO; Canadian Critical Care Trials Group. Patient safety, resident well-being and continuity of care with different resident duty schedules in the intensive care unit: a randomized trial. CMAJ. 2015 Mar 17;187(5):321-9. PMID: 25667258 |
| Karam O | Am J Respir Crit Care Med | 2015 | Indications and Effects of Plasma Transfusions in Critically Ill Children. | 25859890 | Karam O, Demaret P, Shefler A, Leteurtre S, Spinella P, Stanworth S, Tucci M; Canadian Critical Care Trials Group (CCCTG), Pediatric Acute Lung Injury and Sepsis Investigators (PALISI), BloodNet, and the PlasmaTV investigators. Indications and Effects of Plasma Transfusions in Critically Ill Children. Am J Respir Crit Care Med. 2015 Jun 15;191(12):1395-402. PMID: 25859890 |
| Fowler RA | Crit Care | 2015 | Critical Care capacity in Canada: results of a national cross-sectional study. | 25888116 | Fowler RA, Abdelmalik P, Wood G, Foster D, Gibney N, Bandrauk N, Turgeon AF, Lamontagne F, Kumar A, Zarychanski R, Green R, Bagshaw SM, Stelfox HT, Foster R, Dodek P, Shaw S, Granton J, Lawless B, Hill A, Rose L, Adhikari NK, Scales DC, Cook DJ, Marshall JC, Martin C, Jouvet P; Canadian Critical Care Trials Group and The Canadian ICU Capacity Group. Critical Care capacity in Canada: results of a national cross-sectional study. Crit Care. 2015 Apr 1;19(1):133. PMID: 25888116 |
| Daneman N | Trials | 2015 | Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE): study protocol for a pilot randomized controlled trial. | 25903783 | Daneman N, Rishu AH, Xiong W, Bagshaw SM, Cook DJ, Dodek P, Hall R, Kumar A, Lamontagne F, Lauzier F, Marshall JC, Martin CM, McIntyre L, Muscedere J, Reynolds S, Stelfox HT, Fowler RA; Canadian Critical Care Trials Group. Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE): study protocol for a pilot randomized controlled trial. Trials. 2015 Apr 18;16(1):173. PMID: 25903783 |
| van Beinum A | J Intensive Care Med | 2015 | Exploration of Withdrawal of Life-Sustaining Therapy in Canadian Intensive Care Units. | 25680980 | van Beinum A, Hornby L, Ramsay T, Ward R, Shemie SD, Dhanani S. Exploration of Withdrawal of Life-Sustaining Therapy in Canadian Intensive Care Units. J Intensive Care Med. 2015 Feb 12. [Epub ahead of print] PMID: 25680980 |
| Munshi L | Intensive Care Med | 2015 | Predicting time to death after withdrawal of life-sustaining therapy. | 25944573 | Munshi L, Dhanani S, Shemie SD, Hornby L, Gore G, Shahin J. Predicting time to death after withdrawal of life-sustaining therapy. Intensive Care Med. 2015 Jun;41(6):1014-28. PMID: 25944573 |
| Heyland DK | Crit Care Med | 2015 | The Very Elderly Admitted to ICU: A Quality Finish? | 25901550 | Heyland DK, Cook D, Bagshaw SM, Garland A, Stelfox HT, Mehta S, Dodek P, Kutsogiannis J, Burns K, Muscedere J, Turgeon AF, Fowler R, Jiang X, Day AG; Canadian Critical Care Trials Group and the Canadian Researchers at the End of Life Network. The Very Elderly Admitted to ICU: A Quality Finish?
Crit Care Med. 2015Jul;43(7):1352-60. PMID: 25901550 |
| Parshuram CS | Trials | 2015 | Evaluating processes of care and outcomes of children in hospital (EPOCH): study protocol for a randomized controlled trial. | 26033094 | Parshuram CS, Dryden-Palmer K, Farrell C, Gottesman R, Gray M, Hutchison JS, Helfaer M, Hunt E, Joffe A, Lacroix J, Nadkarni V, Parkin P, Wensley D, Willan AR; Canadian Critical Care Trials Group .Evaluating processes of care and outcomes of children in hospital (EPOCH): study protocol for a randomized controlled trial. Trials. 2015;16(1):245. PMID: 26033094 |
| NICE-SUGAR Study Investigators | Intensive Care Med | 2015 | Intensive versus conventional glucose control in critically ill patients with traumatic brain injury: long-term follow-up of a subgroup of patients from the NICE-SUGAR study | 26088909 | NICE-SUGAR Study Investigators for the Australian and New Zealand Intensive Care Society Clinical Trials Group and the Canadian Critical Care Trials Group. Intensive versus conventional glucose control in critically ill patients with traumatic brain injury: long-term follow-up of a subgroup of patients from the NICE-SUGAR study.
Intensive Care Med. 2015 Jun;41(6):1037-47. PMID: 26088909 |
| Green RS | J Crit Care | 2015 | Postintubation hypotension in intensive care unit patients: A multicenter cohort study. | 26117220 | Green RS, Turgeon AF, McIntyre LA, Fox-Robichaud AE, Fergusson DA, Doucette S, Butler MB, Erdogan M; Canadian Critical Care Trials Group (CCCTG). Postintubation hypotension in intensive care unit patients: A multicenter cohort study. J Crit Care. 2015 Oct;30(5):1055-60. PMID: 26117220 |
| Wald R | Kidney Int | 2015 | Comparison of standard and accelerated initiation of renal replacement therapy in acute kidney injury | 26154928 | Wald, R, Adhikari, NKJ, Smith, OM, Weir, MA, Pope, K, Cohen, A, Thorpe, K, McIntyre, L, Lamontagne, F, Soth, M, Herridge, M, Lapinsky, S, Clark, E, Garg, AX, Hiremath, S, Klein, D, Mazer, CD, Richardson, RMA, Wilcox, EM, Friedrich, JO, Burns, KEA and Bagshaw, SM on behalf of the Canadian Critical Care Trials Group. Comparison of standard and accelerated initiation of renal replacement therapy in acute kidney injury. Kidney Int. 2015 Oct;88(4):897-904. PMID: 26154928 |
| Lacroix J | Transfus Clin Biol | 2015 | The ABLE study: A randomized controlled trial on the efficacy of fresh red cell units to improve the outcome of transfused critically ill adult | 26049675 | Lacroix J, Hébert PC, Fergusson D, Tinmouth A, Capellier G, Tiberghien P, Bardiaux L; Canadian Critical Care Trials Group. The ABLE study: A randomized controlled trial on the efficacy of fresh red cell units to improve the outcome of transfused critically ill adults. Transfus Clin Biol. 2015 Aug;22(3):107-11. French. PMID: 26049675 |
| Burry L | Crit Care Med | 2015 | Recall of ICU Stay in Patients Managed With a Sedation Protocol or a Sedation Protocol With Daily Interruption. | 26181221 | Burry L, Cook D, Herridge M, Devlin JW, Fergusson D, Meade M, Steinberg M, Skrobik Y, Olafson K, Burns K, Dodek P, Granton J, Ferguson N, Jacka M, Tanios M, Fowler R, Reynolds S, Keenan S, Mallick R, Mehta S; SLEAP Investigators and the Canadian Critical Care Trials Group. Recall of ICU Stay in Patients Managed With a Sedation Protocol or a Sedation Protocol With Daily Interruption. Crit Care Med. 2015 Oct;43(10):2180-90. PMID: 26181221 |
| Arabi YM | Am J Respir Crit Care Med | 2015 | Characteristics and Outcomes of Eligible Non-Enrolled Patients in a Mechanical Ventilation Trial of Acute Respiratory Distress Syndrome. | 26192398 | Arabi YM, Cook DJ, Zhou Q, Smith O, Hand L, Turgeon AF, Matte A, Mehta S, Graham R, Brierley K, Adhikari NK, Meade MO, Ferguson ND; Canadian Critical Care Trials Group. Characteristics and Outcomes of Eligible Non-Enrolled Patients in a Mechanical Ventilation Trial of Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2015 Jul 20. [Epub ahead of print] PMID: 26192398 |
| D'Aragon F | Shock | 2015 | Blood pressure targets for vasopressor therapy: a systematic review. | 25895147 | D'Aragon F, Belley-Cote EP, Meade MO, Lauzier F, Adhikari NK, Briel M, Lalu M, Kanji S, Asfar P, Turgeon AF, Fox-Robichaud A, Marshall JC, Lamontagne F; Canadian Critical Care Trials Group. Blood pressure targets for vasopressor therapy: a systematic review. Shock. 2015 Jun;43(6):530-9. PMID: 25895147 |
| McNally JD | Trials | 2015 | Prevention of vitamin D deficiency in children following cardiac surgery: study protocol for a randomized controlled trial. | 26353829 | McNally JD, O'Hearn K, Lawson ML, Maharajh G, Geier P, Weiler H, Redpath S, McIntyre L, Fergusson D, Menon K; Canadian Critical Care Trials Groups. Prevention of vitamin D deficiency in children following cardiac surgery: study protocol for a randomized controlled trial. Trials. 2015 Sep 9;16(1):402. PMID: 26353829 |
| Li G | Medicine | 2015 | Competing Risk Analysis for Evaluation of Dalteparin Versus Unfractionated Heparin for Venous Thromboembolism in Medical-Surgical Critically Ill Patients. | 26356708 | Li G, Cook DJ, Levine MA, Guyatt G, Crowther M, Heels-Ansdell D, Holbrook A, Lamontagne F, Walter SD, Ferguson ND, Finfer S, Arabi YM, Bellomo R, Cooper DJ, Thabane L; PROTECT Investigators for the Canadian Critical Care Trials Group, and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Competing Risk Analysis for Evaluation of Dalteparin Versus Unfractionated Heparin for Venous Thromboembolism in Medical-Surgical Critically Ill Patients. Medicine (Baltimore). 2015 Sep;94(36):e1479. PMID: 26356708 |
| Amrein K | Intensive Care Med. | 2015 | Understanding vitamin D deficiency in intensive care patients. | 26142054 | Amrein K, Christopher KB, McNally JD.Understanding vitamin D deficiency in intensive care patients. Intensive Care Med. 2015 Jul 4. [Epub ahead of print] PMID: 26142054 |
| McNally JD | J Clin Endocrinol Metab | 2015 | 1,25-Dihydroxyvitamin D Levels in Pediatric Intensive Care Units: Risk Factors and Association With Clinical Course. | 26052726 | McNally JD, Menon K, Lawson ML, Williams K, Doherty DR.1,25-Dihydroxyvitamin D Levels in Pediatric Intensive Care Units: Risk Factors and Association With Clinical Course. J Clin Endocrinol Metab. 2015 Aug;100(8):2942-5.PMID: 26052726 |
| McNally JD | Pediatrics | 2015 | Rapid normalization of vitamin D levels: a meta-analysis. | 25511115 | McNally JD, Iliriani K, Pojsupap S, Sampson M, O'Hearn K, McIntyre L, Fergusson D, Menon K. Rapid normalization of vitamin D levels: a meta-analysis. Pediatrics. 2015 Jan;135(1):e152-66. PMID: 25511115 |
| van Beinum A | Crit Care Med | 2015 | Variations in the Operational Process of Withdrawal of Life-Sustaining Therapy. | 26121072 | van Beinum A, Hornby L, Ward R, Ramsay T, Dhanani S. Variations in the Operational Process of Withdrawal of Life-Sustaining Therapy. Crit Care Med. 2015 Oct;43(10):e450-7. PMID: 26121072 |
| van Zanten AR | Crit Care | 2015 | Enteral glutamine supplementation in critically ill patients: a systematic review and meta-analysis. | 26283217 | van Zanten AR, Dhaliwal R, Garrel D, Heyland DK. Enteral glutamine supplementation in critically ill patients: a systematic review and meta-analysis. Crit Care. 2015 Aug 18;19:294. PMID: 26283217 |
| Heyland DK | Intensive Care Med. | 2015 | Recovery after critical illness in patients aged 80 years or older: a multi-center prospective observational cohort study. | 26306719 | Heyland DK, Garland A, Bagshaw SM, Cook D, Rockwood K, Stelfox HT, Dodek P, Fowler RA, Turgeon AF, Burns K, Muscedere J, Kutsogiannis J, Albert M, Mehta S, Jiang X, Day AG. Recovery after critical illness in patients aged 80 years or older: a multi-center prospective observational cohort study.
Intensive Care Med. 2015 Nov;41(11):1911-20. PMID: 26306719 |
| Heyland DK | JPEN J Parenter Enteral Nutr. | 2015 | Glutamine and antioxidants in the critically ill patient: a post hoc analysis of a large-scale randomized trial. | 24803474 | Heyland DK, Elke G, Cook D, Berger MM, Wischmeyer PE, Albert M, Muscedere J, Jones G, Day AG; Canadian Critical Care Trials Group. Glutamine and antioxidants in the critically ill patient: a post hoc analysis of a large-scale randomized trial. JPEN J Parenter Enteral Nutr. 2015 May;39(4):401-9. PMID: 24803474 |
| Rewa O | J Crit Care | 2015 | Whole-blood neutrophil gelatinase-associated lipocalin to predict adverse events in acute kidney injury: A prospective observational cohort study. | 26421697 | Rewa O, Wald R, Adhikari NK, Hladunewich M, Lapinsky S, Muscedere J, Bagshaw SM, Smith OM, Lebovic G, Kuint R, Klein DJ. Whole-blood neutrophil gelatinase-associated lipocalin to predict adverse events in acute kidney injury: A prospective observational cohort study. J Crit Care. 2015 Dec;30(6):1359-64. PMID: 26421697 |
| English SW | Syst Rev. | 2015 | Red blood cell transfusion and mortality effect in aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis protocol. | 25927348 | English SW, Chassé M, Turgeon AF, Tinmouth A, Boutin A, Pagliarello G, Fergusson D, McIntyre L. Red blood cell transfusion and mortality effect in aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis protocol. Syst Rev. 2015 Apr 3;4:41. PMID: 25927348 |
| Duan EH | Intensive Care Med Exp | 2015 | Contemporary Ventilation Strategies And Adjunctive Therapies For Acute Respiratory Distress Syndrome (Ards). | 27290167 | Duan EH, Adhikari NK, Hand L, D'Aragon F, Austin P, Zhou Q, Alhazzani W, Cook DJ, Ferguson ND, Meade MO; Canadian Critical Care Trials Group. Contemporary Ventilation Strategies And Adjunctive Therapies For Acute Respiratory Distress Syndrome (Ards). Intensive Care Med Exp. 2015 Dec;3(Suppl 1):A6. PMID: 27290167 |
| Menon K | Shock | 2015 | A Cohort Study of Pediatric Shock: Frequency of Corticosteriod Use and Association with Clinical Outcomes. | 25692259 | Menon K, McNally JD, Choong K, Lawson ML, Ramsay T, Hutchison JS, Foster J, Wong HR; Canadian Critical Care Trials Group STRIPES Investigators. A Cohort Study of Pediatric Shock: Frequency of Corticosteriod Use and Association with Clinical Outcomes. Shock. 2015 Nov;44(5):402-9. PMID: 25692259 |
| Lamontagne F | JAMA Intern Med. | 2014 | Non-leg venous thrombi during critical illness: a nested prospective cohort study. | 24638843 | Lamontagne F, Heels-Ansdell D, McIntyre L, Dodek P, Meade M, Skrobik Y, McDonald E, Vallance S, Zytaruk N, Cook D, for the PROTECT Investigators, on behalf of the CCCTG and the ANZICS-CTG. Non-leg venous thrombi during critical illness: a nested prospective cohort study. JAMA Intern Med. 2014;174(5):689-96. PMID:24638843 |
| Crowther M | J Crit Care | 2014 | Heparin-induced thrombocytopenia in the critically ill: interpreting the 4Ts test in a randomized trial. | 24726205 | Crowther M, Cook D, Guyatt G, Zytaruk N, McDonald E, Williamson D, Albert M, Dodek P, Finfer S, Vallance S, Heels-Ansdell D, McIntyre L, Mehta S, Lamontagne F, Muscedere J, Jacka M, Lesur O, Kutsiogiannis J, Friedrich J1, Klinger JR, Qushmaq I, Burry L, Khwaja K, Sheppard JA, Warkentin TE; PROTECT collaborators; Canadian Critical Care Trials Group; Australian and New Zealand Intensive Care Society Clinical Trials Group.Heparin-induced thrombocytopenia in the critically ill: interpreting the 4Ts test in a randomized trial. J Crit Care. 2014 Jun;29(3):470.e7-15. PMID:24726205 |
| Lauzier F | Crit Care | 2014 | Thromboprophylaxis patterns and determinants in critically ill patients: a multicenter audit. | 24766968 | Lauzier F, Muscedere J, Deland E, Kutsogiannis DJ, Jacka M, Heels-Ansdell D, Crowther M, Cartin-Ceba R, Cox MJ, Zytaruk N, Foster D, Sinuff T, Clarke F, Thompson P, Hanna S, Cook D; Co-operative Network of Critical Care Knowledge Translation for Thromboprophylaxis (CONECCKT-T) Investigators; Canadian Critical Care Trials Group. Thromboprophylaxis patterns and determinants in critically ill patients: a multicenter audit. Crit Care. 2014;18(2):R82. PMID:24766968 |
| Choong K | Pediatr Crit Care Med | 2014 | Acute rehabilitation practices in critically ill children: a multicenter study | 24777303 | Choong K1, Foster G, Fraser DD, Hutchison JS, Joffe AR, Jouvet PA, Menon K, Pullenayegum E, Ward RE. Canadian Critical Care Trials Group. Acute rehabilitation practices in critically ill children: a multicenter study. Pediatr Crit Care Med. 2014;15(6):e270-9. PMID:24777303 |
| Heyland DK | J Parenter Enteral Nutr | 2014 | Glutamine and Antioxidants in the Critically Ill Patient: A Post Hoc Analysis of a Large-Scale Randomized Trial. | 24803474 | Heyland DK, Elke G, Cook D, Berger MM, Wischmeyer PE, Albert M, Muscedere J, Jones G, Day AG on behalf of the Canadian Critical Care Trials Group.Glutamine and Antioxidants in the Critically Ill Patient: A Post Hoc Analysis of a Large-Scale Randomized Trial. JPEN J Parenter Enteral Nutr. 2014 May 5. PMID: 24803474 |
| Cook D | J Crit Care | 2014 | Barriers and facilitators of thromboprophylaxis for medical-surgical intensive care unit patients: a multicenter survey. | 24629574 | Cook D, Duffett M2, Lauzier F3, Ye C4, Dodek P5, Paunovic B6, Fowler R7, Kho ME8, Foster D9, Stelfox T10, Sinuff T7, Zytaruk N4, Clarke F4, Wood G11, Cox M12, Kutsiogiannis J13, Jacka M13, Roussos M14, Kumar H15, Guyatt G16; CONECCKT-T (Co-operative Network of Critical Care Knowledge Translation for Thromboprophylaxis) Investigators; Canadian Critical Care Trials Group.Barriers and facilitators of thromboprophylaxis for medical-surgical intensive care unit patients: a multicenter survey.
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| Burns K | Can Respir J | 2014 | Evaluation of an internal review process for grants and manuscripts in the Canadian Critical Care Trials Group. | 24712017 | Burns KE, Caon E, Dodek PM. Evaluation of an internal review process for grants and manuscripts in the Canadian Critical Care Trials Group. Can Respir J. 2014 21(5):283-6. PMID: 24712017 |
| Steinberg M | J Intensive Care Med | 2014 | A National Survey of Critical Care Physicians' Knowledge, Attitudes, and Perceptions of Antimicrobial Stewardship Programs. | 25005699 | Steinberg M, Dresser LD, Daneman N, Smith OM, Matte A, Marinoff N, Bell CM, Morris AM.A National Survey of Critical Care Physicians' Knowledge, Attitudes, and Perceptions of Antimicrobial Stewardship Programs.J Intensive Care Med. 2014 Jul 8. [Epub ahead of print]. PMID: 25005699 |
| Dhanani S | Crit Care Med | 2014 | Vital signs after cardiac arrest following withdrawal of life-sustaining therapy: a multicenter prospective observational study | 24810533 | Dhanani S, Hornby L, Ward R, Baker A, Dodek P, Chamber-Evans J, Fowler R, Friedrich JO, Gow RM, Kutsogiannis DJ, Mcintyre L, Momoli F, Morin K, Ramsay T, Scales D, Writer H, Yildirim S, Young B, Shemie S; Canadian Critical Care Trials Group and in collaboration with the Bertram Loeb Chair and Research Consortium in Organ and Tissue Donation.Vital signs after cardiac arrest following withdrawal of life-sustaining therapy: a multicenter prospective observational study*. Crit Care Med. 2014 Nov;42(11):2358-69. PMID: 24810533 |
| Fowler RA | JAMA | 2014 | Cost-effectiveness of Dalteparin vs Unfractionated Heparin for the Prevention of Venous Thromboembolism in Critically Ill Patients. | 25362228 | Fowler RA, Mittmann N, Geerts W, Heels-Ansdell D, Gould MK, Guyatt G, Krahn M, Finfer S, Pinto R, Chan B, Ormanidhi O, Arabi Y, Qushmaq I, Rocha MG, Dodek P, McIntyre L, Hall R, Ferguson ND, Mehta S, Marshall JC, Doig CJ, Muscedere J, Jacka MJ, Klinger JR, Vlahakis N, Orford N, Seppelt I, Skrobik YK, Sud S, Cade JF, Cooper J, Cook D; for the Canadian Critical Care Trials Group and the Australia and New Zealand Intensive Care Society Clinical Trials Group.Cost-effectiveness of Dalteparin vs Unfractionated Heparin for the Prevention of Venous Thromboembolism in Critically Ill Patients.JAMA. 2014 312(20):2135-45.PMID:25362228 |
| Cahill NE | Crit Care | 2014 | Implementing a multifaceted tailored intervention to improve nutrition adequacy in critically ill patients: results of a multicenter feasibility study | 24887445 | Cahill NE, Murch L, Cook D, Heyland DK; Canadian Critical Care Trials Group. Implementing a multifaceted tailored intervention to improve nutrition adequacy in critically ill patients: results of a multicenter feasibility study.Crit Care. 2014 May 11;18(3):R96. PMID: 24887445 |
| Cahill NE | Nutr Clin Pract. | 2014 | Improving the provision of enteral nutrition in the intensive care unit: a description of a multifaceted intervention tailored to overcome local barriers. | 24344255 | Cahill NE, Murch L, Cook D, Heyland DK; Canadian Critical Care Trials Group.Improving the provision of enteral nutrition in the intensive care unit: a description of a multifaceted intervention tailored to overcome local barriers.Nutr Clin Pract. 2014 Feb;29(1):110-7. PMID: 24344255 |
| Seely A | Crit Care | 2014 | Do heart and respiratory rate variability improve prediction of extubation outcomes in critically ill patients? | 24713049 | Seely A, Bravi A, Herry C, Green G, Longtin A, Ramsay T, Fergusson D, McIntyre L, Kubelik D, Maziak DE, Ferguson N, Brown SM, Mehta S, Martin C, Rubenfeld G, Jacono FJ, Clifford G, Fazekas A, Marshall J; The Canadian Critical Care Trials Group (CCCTG); The Canadian Critical Care Trials Group CCCTG. Do heart and respiratory rate variability improve prediction of extubation outcomes in critically ill patients?Crit Care. 2014 Dec 2;18(6):620. PMID: 24713049 |
| Archambault, PM | JMIR Res Protoc | 2014 | Development and validation of questionnaires exploring health care professionals' intention to use wiki-based reminders to promote best practices in trauma | 25281856 | Archambault PM, Gagnon S, Gagnon MP, Turcotte S, Lapointe J, Fleet R, Côté M, Beaupré P, Le Sage N, Emond M, Légaré F., Canadian Critical Care Trials Group. Development and validation of questionnaires exploring health care professionals' intention to use wiki-based reminders to promote best practices in trauma. JMIR Res Protoc., 2014;3(3):e50. PMID: 25281856 |
| Wald R | Am J Kidney Dis | 2014 | Changing Incidence and Outcomes Following Dialysis-Requiring Acute Kidney Injury Among Critically Ill Adults: A Population-Based Cohort Study. | 25533599 | Wald R, McArthur E, Adhikari NK, Bagshaw SM, Burns KE, Garg AX, Harel Z, Kitchlu A, Mazer CD, Nash DM, Scales DC, Silver SA, Ray JG, Friedrich JO. Changing Incidence and Outcomes Following Dialysis-Requiring Acute Kidney Injury Among Critically Ill Adults: A Population-Based Cohort Study. Am J Kidney Dis. 2015 Jun;65(6):870-7. PMID: 25533599 |
| Burns KE | Cochrane Database of Systematic Reviews | 2014 | Automated weaning and SBT systems versus non-automated weaning strategies for weaning time in invasively ventilated critically ill adults | 25203308 | Burns KEA, Lellouche F, Nisenbaum R, Lessard MR, Friedrich JO. Automated weaning and SBT systems versus non-automated weaning strategies for weaning time in invasively ventilated critically ill adults. Cochrane Database of Systematic Reviews 2014, Sep 9;9:CD008638. PMID: 25203308 |
| Burns KE | J Clin Trials | 2014 | The Approach Trial: A Mixed Methods Pilot RCT Comparing Alternative Strategies for Approaching Substitute Decision Makers for Proxy Consent for Research Participation. | | Burns KEA, Rizvi L, Smith OM, Mehta S. The Approach Trial: A Mixed Methods Pilot RCT Comparing Alternative Strategies for Approaching Substitute Decision Makers for Proxy Consent for Research Participation. J Clin Trials 2014, 4:164. DOI:10.4172/2167-0870.1000164. |
| Burns KE | Cochrane Database of Systematic Review | 2014 | SmartCare™ versus non-automated mechanical ventilation strategies on discontinuation time for adults in the postoperative period | 24526330 | Burns KEA, Lellouche F, Nisenbaum R, Lessard M, Friedrich J, Blackwood B. SmartCare™ versus non-automated mechanical ventilation strategies on discontinuation time for adults in the postoperative period. Cochrane Database of Systematic Reviews 2014. Issue 2. Art. No.: CD008639. DOI: 10.1002/14651858.CD008639.pub2).PMID: 24526330 |
| Hosein FS | Crit Care | 2014 | A meta-analysis to derive literature-based benchmarks for readmission and hospital mortality after patient discharge from intensive care. | 25551448 | Hosein FS, Roberts DJ, Turin TC, Zygun D, Ghali WA, Stelfox HT. A meta-analysis to derive literature-based benchmarks for readmission and hospital mortality after patient discharge from intensive care. Crit Care. 2014;18(6):2558.PMID: 25551448 |
| Menon K | J Med Ethics | 2014 | A Study of Consent for Participation in a Non-Therapeutic Study in the Pediatric Intensive Care Population. | 23345569 | Menon K, Ward R. A Study of Consent for Participation in a Non-Therapeutic Study in the Pediatric Intensive Care Population. J Med Ethics 2014;40(2):123-6. PMID: 23345569 |
| Mehta S | Ann Intensive Care | 2014 | A ventilator strategy combining low tidal volume ventilation, recruitment maneuvers, and high positive end-expiratory pressure does not increase sedative, opioid, or neuromuscular blocker use in adults with acute respiratory distress syndrome and may improve patient comfort. | 25593749 | Mehta S, Cook DJ, Skrobik Y, Muscedere J, Martin CM, Stewart TE, Burry LD, Zhou Q, Meade M.A ventilator strategy combining low tidal volume ventilation, recruitment maneuvers, and high positive end-expiratory pressure does not increase sedative, opioid, or neuromuscular blocker use in adults with acute respiratory distress syndrome and may improve patient comfort.Ann Intensive Care. 2014;4:33. PMID: 25593749 |
| Fowler RA | Trials | 2014 | Economic evaluation of the prophylaxis for thromboembolism in critical care trial (E-PROTECT): study protocol for a randomized controlled trial. | 25528663 | Fowler RA, Mittmann N, Geerts WH, Heels-Ansdell D, Gould MK, Guyatt G, Krahn M, Finfer S, Pinto R, Chan B, Ormanidhi O, Arabi Y, Qushmaq I, Rocha MG, Dodek P, McIntyre L, Hall R, Ferguson ND, Mehta S, Marshall JC, Doig CJ, Muscedere J, Jacka MJ, Klinger JR, Vlahakis N, Orford N, Seppelt I, Skrobik YK, Sud S, Cade JF, Cooper J, Cook D.Economic evaluation of the prophylaxis for thromboembolism in critical care trial (E-PROTECT): study protocol for a randomized controlled trial. Trials. 2014;15(1):502. PMID: 25528663 |
| Francis JJ | Health Technol Assess | 2014 | Selective decontamination of the digestive tract in critically ill patients treated in intensive care units: a mixed-methods feasibility study (the SuDDICU study). | 24775071 | Francis JJ, Duncan EM, Prior ME, Maclennan GS, Dombrowski S, Bellingan GU, Campbell MK, Eccles MP, Rose L, Rowan KM, Shulman R, Peter R Wilson A, Cuthbertson BH. Selective decontamination of the digestive tract in critically ill patients treated in intensive care units: a mixed-methods feasibility study (the SuDDICU study). Health Technol Assess. 2014;18(25):1-170.PMID: 24775071 |
| Canter RR | Br J Anaesth | 2014 | Observational study of current use of selective decontamination of the digestive tract in UK critical care units. | 24829442 | Canter RR, Harvey SE, Harrison DA, Campbell MK, Rowan KM, Cuthbertson BH; Selective Decontamination of the Digestive tract in critically ill patients treated in Intensive Care Unit (SuDDICU) Investigators.Observational study of current use of selective decontamination of the digestive tract in UK critical care units. Br J Anaesth. 2014;113(4):610-7. PMID: 24829442 |
| Duncan EM | J Crit Care. | 2014 | For the SuDDICU International Study Group. The views of health care professionals about selective decontamination of the digestive tract: An international, theoretically informed interview study | 24747038 | Duncan EM, Cuthbertson BH, Prior ME, Marshall AP, Wells EC, Todd LE, Bolsover D, Newlands RS, Webster F, Rose L, Campbell MK, Bellingan G, Seppelt IM, Francis JJ; For the SuDDICU International Study Group. The views of health care professionals about selective decontamination of the digestive tract: An international, theoretically informed interview study. J Crit Care. 2014;29(4):634-10.PMID: 24747038 |
| Francis JJ | Br J Health Psychol. | 2014 | Comparison of four methods for assessing the importance of attitudinal beliefs: An international Delphi study in intensive care settings. | 24112280 | Francis JJ, Duncan EM, Prior ME, Maclennan G, Marshall AP, Wells EC, Todd L, Rose L, Campbell MK, Webster F, Eccles MP, Bellingan G, Seppelt IM, Grimshaw JM, Cuthbertson BH; for the SuDDICU study groups. Comparison of four methods for assessing the importance of attitudinal beliefs: An international Delphi study in intensive care settings. Br J Health Psychol. 2014;19(2):274-91. PMID: 24112280 |
| Marshall AP | Heart Lung. | 2014 | Implementing selective digestive tract decontamination in the intensive care unit: A qualitative analysis of nurse-identified consideration | 24239299 | Marshall AP, Weisbrodt L, Rose L, Duncan E, Prior M, Todd L, Wells E, Seppelt I, Cuthbertson B, Francis J. Implementing selective digestive tract decontamination in the intensive care unit: A qualitative analysis of nurse-identified considerations. Heart Lung. 2014;43(1):13-8. PMID: 24239299 |
| Albert M | Intensive Care Med | 2014 | Candida in the Respiratory Tract Secretions of Critically Ill Patients and The Efficacy of Antifungal Treatment: a randomized placebo controlled trial (CANTREAT Study) | 24981955 | Albert, M, Williamson, D, Muscedere, J, Lauzier, F, Rotstein, C, Kanji, S, Jiang, X, Hall, M, Heyland, DK.
Candida in the Respiratory Tract Secretions of Critically Ill Patients and The Efficacy of Antifungal Treatment: a randomized placebo controlled trial (CANTREAT Study) Intensive Care Medecine 2014; 40: 1313–1322. PMID: 24981955 |
| Shemie S | Intensive Care Med | 2014 | International guideline development for the determination of death. | 24664151 | Shemie SD, Hornby L, Baker A, Teitelbaum J, Torrance S, Young K, Capron AM, Bernat JL, Noel L; The International Guidelines for Determination of Death phase 1 participants, in collaboration with the World Health Organization. International guideline development for the determination of death. Intensive Care Med. 2014;40(6):788-97. PMID: 24664151 |
| Demaret P | Transfusion | 2014 | Red blood cell transfusion in critically ill children (CME) | 24517132 | Demaret P, Tucci M, Ducruet T, Trottier H, Lacroix J. Red blood cell transfusion in critically ill children (CME). Transfusion. 2014 Feb;54(2):365-75. PMID: 24517132 |
| Karam O | Transfusion | 2014 | International survey on plasma transfusion practices in critically ill children. | 24032693 | Karam O, Tucci M, Lacroix J, Rimensberger PC; Canadian Critical Care Trials Group and of the Pediatric Acute Lung Injury and Sepsis Investigator Network.. International survey on plasma transfusion practices in critically ill children. Transfusion. 2014 Apr;54(4):1125-32. PMID: 24032693 |
| Du Pont-Thibodeau G | Pediatr Crit Care Med | 2014 | Survey on stated transfusion practices in PICUs | 24732292 | Du Pont-Thibodeau G1, Tucci M, Ducruet T, Lacroix J. Survey on stated transfusion practices in PICUs. Pediatr Crit Care Med. 2014 Jun;15(5):409-16. PMID: 24732292
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| Wald R | Crit Care Med. | 2014 | The association between renal replacement therapy modality and long-term outcomes among critically ill adults with acute kidney injury: a retrospective cohort study*. | 24275513 | Wald R, Shariff SZ, Adhikari NK, Bagshaw SM, Burns KE, Friedrich JO, Garg AX, Harel Z, Kitchlu A, Ray JG.The association between renal replacement therapy modality and long-term outcomes among critically ill adults with acute kidney injury: a retrospective cohort study*. Crit Care Med. 2014 Apr;42(4):868-77. PMID: 24275513 |
| Menon K | Pediatr Crit Care Med | 2013 | A Survey of Physician Practices and Beliefs on the Use of Steroids in Pediatric Shock | 23628832 | Menon K, McNally D, Choong K, Lawson M, Ward R, Ramsay T, Wong H for the Canadian Critical Care Trials Group. A Survey of Physician Practices and Beliefs on the Use of Steroids in Pediatric Shock. Pediatric Critical Care Medicine. Pediatr Crit Care Med. 2013;14(5):462-6. PMID:23628832 |
| Sinuff T. | Critical Care Medicine | 2013 | Clinical Practice Guidelines for Ventilator Associated Pneumonia: A Multicentre Prospective Study | 23222254 | T. Sinuff, J. Muscedere, D.J. Cook, P. M. Dodek, W. Anderson, S. P. Keenan, G. Wood, R. Tan, M.T. Haupt, M. Miletin, R. Bouali, X. Jiang, Day A.G., Overvelde J, D.K. Heyland for the Canadian Critical Care Trials Group. Implementation of clinical practice guidelines for ventilator-associated pneumonia: a multicenter prospective study. Crit Care Med. 2013;41(1):15-23. PMID:23222254 |
| Burns KE | Critical Care Medicine | 2013 | Participation of Intensive Care Units in Critical Care Pandemic Research: A Province Wide, Cross-Sectional Survey | 23385105 | Burns KEA, Rizvi L, Tan W, Marshall JC, Pope K for the Canadian Critical Care Trials Group. Participation of Intensive Care Units in Critical Care Pandemic Research: A Province Wide, Cross-Sectional Survey. Crit Care Med. 2013;41(4):1009-16. PMID:23385105 |
| Thomas M | Dynamics | 2013 | Consenting to Pediatric Research: Understanding the Parent’s Perspective. | 24288878 | Thomas M, Menon K for the Canadian Critical Care Trials Group. Consenting to Pediatric Research: Understanding the Parent’s Perspective. Dynamics 2013;24(3):18-24. PMID:24288878 |
| McNally DJ | Anesthesiology | 2013 | Impact of Anesthesia and Surgery for Congenital Heart Disease on the Vitamin D Status of Infants and Children A Prospective Longitudinal Study | 23470437 | McNally DJ, Menon K, Chakraborty P, Fisher L, Williams KA, Al-Dirbashi OY, Girolamo T, Maharajh T, Doherty DR. Impact of Anesthesia and Surgery for Congenital Heart Disease on the Vitamin D Status of Infants and Children A Prospective Longitudinal Study. Anesthesiology 2013;119(1):71-80. PMID:23470437 |
| Havey TC | Can J. of ID & MM | 2013 | Duration of Antibiotic Therapy for Critically Ill Patients with Bloodstream Infections: A Retrospective Cohort Study. | 24421823 | Havey TC, Fowler RA, Pinto R, Elligsen M, Daneman N. Duration of Antibiotic Therapy for Critically Ill Patients with Bloodstream Infections: A Retrospective Cohort Study. Can J Infect Dis Med Microbiol. 2013;24(3):129-37. PMID:24421823 |
| Burns KE | Am J Respir Crit Care Med. | 2013 | Wean Earlier and Automatically with New Technology (The WEAN Study): A Multicentre Pilot RCT. | | Burns KE, Meade MO, Lessard MR, Hand L, Zhou Q, Keenan SP, Lellouche F. Wean Earlier and Automatically with New Technology (The WEAN Study): A Multicentre Pilot RCT. Am J Respir Crit Care Med. 2013 Jun 1;187(11):1203-11. |
| Cook DJ | Crit Care | 2013 | Coenrolment of Critically Ill Patients into Multiple Studies: Patterns, Predictors and Consequences. | | Cook DJ, McDonald E, Smith O, Zytaruk N, Heels-Ansdell D, Watpool I, McArdle T, Matte A, Clarke F, Vallance S, Finfer S, Galt P, Crozier T, Fowler R, Arabi Y, Woolfe C, Orford N, Hall R, Adhikari N, Ferland MC, Marshall JD, Meade M for the PROTECT Investigators, CCCTG and ANZICS-CTG. Coenrolment of Critically Ill Patients into Multiple Studies: Patterns, Predictors and Consequences. Crit Care 2013;17:R1-R8. |
| Daneman N | Lancet Infect Dis. | 2013 | Effect of selective decontamination on antimicrobial resistance in intensive care units: a systematic review and meta-analysis. | | Daneman N, Sarwar S, Fowler RA, Cuthbertson BH. Effect of selective decontamination on antimicrobial resistance in intensive care units: a systematic review and meta-analysis. Lancet Infect Dis. 2013 Apr;13(4):328-41. |
| Burns K | Crit Care Med. | 2013 | Participation of Ontario Intensive Care Units in Critical Care Pandemic Research. | | Burns K, Rizvi L, Tan W, Marshall JC, Pope K. Participation of Ontario Intensive Care Units in Critical Care Pandemic Research. Crit Care Med. 2013 Apr;41(4):1009-1016. |
| Lamontagne F | Can J Anaesth. | 2013 | Corticosteroid in the Intensive Care Unit: A Survey of Intensivists. | | Lamontagne F, Martinez HQ, Adhikari N, Cook D, Koo K, Lauzier F, Turgeon A, Kho M, Burns KEA, Chant C, Fowler R, Douglas I, Poulin Y, Choong K, Ferguson ND, Meade MO. Corticosteroid in the Intensive Care Unit: A Survey of Intensivists. Can J Anaesth. 2013 Apr 19. [Epub ahead of print] |
| Turgeon AF | Crit Care Med. | 2013 | Determination of neurologic prognosis and clinical decision making in adult patients with severe traumatic brain injury: a survey of Canadian intensivists, neurosurgeons, and neurologists. | 23385104 | Turgeon AF, Lauzier F, Burns KE, Meade MO, Scales DC, Zarychanski R, Moore L, Zygun DA, McIntyre LA, Kanji S, Hébert PC, Murat V, Pagliarello G, Fergusson DA; for the Canadian Critical Care Trials Group. Determination of neurologic prognosis and clinical decision making in adult patients with severe traumatic brain injury: a survey of Canadian intensivists, neurosurgeons, and neurologists. Crit Care Med. 2013 Apr;41(4):1086-93. PMID: 23385104 |
| Burns KE | Am J Respir Crit Care Med. | 2013 | Research Recruitment Practices of Critically Ill Patients: A Multicenter, Cross-Sectional Study (The Consent Study) | 23525935 | Burns KE, Zubrinich C, Tan W, Raptis S, Xiong W, Smith O, McDonald E, Marshall JC, Saginur R, Heslegrave R, Rubenfeld G, Cook DJ; for the Canadian Critical Care Trials Group. Research Recruitment Practices of Critically Ill Patients: A Multicenter, Cross-Sectional Study (The Consent Study). Am J Respir Crit Care Med. 2013 Jun 1;187(11):1212-8. [Epub ahead of print]. PMID: 23525935 |
| Smith OM | J Crit Care | 2013 | Rates and determinants of informed consent: A case study of an international thromboprophylaxis trial. | 23089679 | Smith OM, McDonald E, Zytaruk N, Foster D, Matte A, Clarke F, Meade L, O’Callaghan N, Vallance S, Galt P, Rajbhandari D, Rocha M, Mehta S, Ferguson ND, Hall R, Fowler R, Burns K, Qushmaq I, Ostermann M, Heels-Ansdell, Cook DJ for the PROTECT Research Coordinators, PROTECT Investigators, Canadian Critical Care Trials Group, and the Australian, New Zealand Intensive Care Society Clinical Trials Group. Rates and determinants of informed consent: A case study of an international thromboprophylaxis trial. J Crit Care 2013;28: 28-39. PMID: 23089679 |
| Koo KK | Am J Respir Crit Care Med (in press) | 2013 | Inter-rater Reliability of Observed, Stated and Documented Acute Rehabilitation in Canadian Intensive Care Units. | | Koo KK, Cook DJ, Lamontagne F, Campbell E, Hand L, Clarke F, Zytaruk N, McLeod A, Soucy I, Boutin M, Priestap F, Meade MO on behalf of the Canadian Critical Care Trials Group. Inter-rater Reliability of Observed, Stated and Documented Acute Rehabilitation in Canadian Intensive Care Units. Am J Respir Crit Care Med 2013 (in press) |
| Clarke F | Crit Care Med | 2013 | Knowledge Translation for Thromboprophylaxis (CONECCKT-T) | | Clarke F, Foster D, Laberge A, O'Callaghan N, Thompson P, Meade L, Julien L, Watpool I, Ashley BJ, Marinoff N, Cook D, for the Co-operative Network of Critical Care Knowledge Translation for Thromboprophylaxis (CONECCKT-T) Investigators and the CCCTG REB and Contract Approval Times for a Multicenter Audit. Crit Care Med 2013 (in press). |
| Cook D | Intensive Care Med | 2013 | Physicians declining patient enrollment in a critical care trial: a case study in thromboprophylaxis | 24022796 | Cook D, Arabi Y, Ferguson N, Heels-Ansdell D, Freitag A, McDonald E, Clarke F, Keenan S, Pagliarello G, Plaxton W, Herridge M, Karachi T, Vallance S, Cade J, Crozier T, Alves da Silva S, Costa Filho R, Brandao N, Watpool I, McArdle T, Hollinger G, Mandourah Y, Al-Hazmi M, Zytaruk N, Adhikari NK; PROTECT Research Coordinators; PROTECT Investigators; Canadian Critical Care Trials Group; Australian and New Zealand Intensive Care Society Clinical Trials Group. Physicians declining patient enrollment in a critical care trial: a case study in thromboprophylaxis. Intensive Care Med. 2013;39(12):2115-25. PMID:24022796 |
| Bagshaw SM | BMC Nephrol. | 2013 | Acute kidney injury among critically ill patients with pandemic H1N1 influenza A in Canada: cohort study. | 23763900 | Bagshaw SM,Sood MM, Long J, Fowler RA, Adhikari NK; Canadian Critical Care Trials Group H1N1 Collaborative. Acute kidney injury among critically ill patients with pandemic H1N1 influenza A in Canada: cohort study. BMC Nephrol. 2013;14:123. PMID:23763900 |
| Muscedere J | Chest | 2013 | The occurrence and impact of bacterial organisms complicating critical care illness associated with 2009 influenza A(H1N1) infection. | 23392627 | Muscedere J, Ofner M, Kumar A, Long J, Lamontagne F, Cook D, McGeer A, Chant C, Marshall J, Jouvet P, Fowler R; ICU-FLU Group; Canadian Critical Care Trials Group. The occurrence and impact of bacterial organisms complicating critical care illness associated with 2009 influenza A(H1N1) infection. Chest. 2013 Jul;144(1):39-47. PMID:23392627 |
| Feguson ND | Am J Respir Crit Care Med | 2013 | Integrating mortality and morbidity outcomes: using quality-adjusted life years in critical care trials. | 23204250 | Ferguson ND, Scales DC, Pinto R, Wilcox ME, Cook DJ, Guyatt GH, Schünemann HJ, Marshall JC, Herridge MS, Meade MO; Canadian Critical Care Trials Group. Integrating mortality and morbidity outcomes: using quality-adjusted life years in critical care trials. Am J Respir Crit Care Med. 2013;187(3):256-61. PMID:23204250 |
| Muscedere J | Chest | 2013 | The clinical impact and preventability of ventilator-associated conditions in critically ill patients who are mechanically ventilated | 24030318 | Muscedere J, Sinuff T, Heyland DK, Dodek PM, Keenan SP, Wood G, Jiang X, Day AG, Laporta D, Klompas M; Canadian Critical Care Trials Group. The clinical impact and preventability of ventilator-associated conditions in critically ill patients who are mechanically ventilated. Chest. 2013 Nov;144(5):1453-60. PMID: 24030318 |
| Sinuff T | Crit Care Med | 2013 | Knowledge translation interventions for critically ill patients: a systematic review | 23939356 | Sinuff T, Muscedere J, Adhikari NK, Stelfox HT, Dodek P, Heyland DK, Rubenfeld GD, Cook DJ, Pinto R, Manoharan V, Currie J, Cahill N, Friedrich JO, Amaral A, Piquette D, Scales DC, Dhanani S, Garland A; KRITICAL Working Group, the Canadian Critical Care Trials Group, and the Canadian Critical Care Society. Knowledge translation interventions for critically ill patients: a systematic review. Crit Care Med. 2013;41(11):2627-4. PMID: 23939356 |
| Williamson DR | Chest | 2013 | Thrombocytopenia in critically ill patients receiving thromboprophylaxis: frequency, risk factors, and outcomes. | 23788287 | Williamson DR, Albert M, Heels-Ansdell D, Arnold DM, Lauzier F, Zarychanski R, Crowther M, Warkentin TE, Dodek P, Cade J, Lesur O, Lim W, Fowler R, Lamontagne F, Langevin S, Freitag A, Muscedere J, Friedrich JO, Geerts W, Burry L, Alhashemi J, Cook D; PROTECT collaborators; Canadian Critical Care Trials Group; Australian and New Zealand Intensive Care Society Clinical Trials Group. Thrombocytopenia in critically ill patients receiving thromboprophylaxis: frequency, risk factors, and outcomes. Chest. 2013 Oct;144(4):1207-15. PMID: 23788287 |
| Warkentin TE | Chest | 2013 | Heparin-induced thrombocytopenia in medical surgical critical illness. | 23722881 | Warkentin TE, Sheppard JA, Heels-Ansdell D, Marshall JC, McIntyre L, Rocha MG, Mehta S, Davies AR, Bersten AD, Crozier TM, Ernest D, Vlahakis NE, Hall RI, Wood GG, Poirier G, Crowther MA, Cook DJ; Canadian Critical Care Trials Group; Australian and New Zealand Intensive Care Society Clinical Trials Group. Heparin-induced thrombocytopenia in medical surgical critical illness. Chest. 2013 Sep;144(3):848-58. PMID: 23722881 |
| Heyland DK | N Engl J Med | 2013 | A randomized trial of glutamine and antioxidants in critically ill patients | 23594003 | Heyland D, Muscedere J, Wischmeyer PE, Cook D, Jones G, Albert M, Elke G, Berger MM, Day AG; Canadian Critical Care Trials Group. A randomized trial of glutamine and antioxidants in critically ill patients.N Engl J Med. 2013;368(16):1489-97. PMID: 23594003 |
| Smith OM | Trials | 2013 | Standard versus accelerated initiation of renal replacement therapy in acute kidney injury (STARRT-AKI): study protocol for a randomized controlled trial. | 24093950 | Smith OM, Wald R, Adhikari NK, Pope K, Weir MA, Bagshaw SM; Canadian Critical Care Trials Group. Standard versus accelerated initiation of renal replacement therapy in acute kidney injury (STARRT-AKI): study protocol for a randomized controlled trial. Trials. 2013;14:320. PMID: 24093950 |
| Ferguson ND | N Engl J Med | 2013 | High-frequency oscillation in early acute respiratory distress syndrome. | 23339639 | Ferguson ND, Cook DJ, Guyatt GH, Mehta S, Hand L, Austin P, Zhou Q, Matte A, Walter SD, Lamontagne F, Granton JT, Arabi YM, Arroliga AC, Stewart TE, Slutsky AS, Meade MO; OSCILLATE Trial Investigators; Canadian Critical Care Trials Group.High-frequency oscillation in early acute respiratory distress syndrome.N Engl J Med. 2013 Feb 28;368(9):795-805. PMID: 23339639 |
| Cahill NE | Implement Sci | 2013 | Development and psychometric properties of a questionnaire to assess barriers to feeding critically ill patients. | 24305039 | mplement Sci. 2013 Dec 4;8:140. doi: 10.1186/1748-5908-8-140.
Development and psychometric properties of a questionnaire to assess barriers to feeding critically ill patients.
Cahill NE, Day AG, Cook D, Heyland DK; Canadian Critical Care Trials Group.Development and psychometric properties of a questionnaire to assess barriers to feeding critically ill patients.Implement Sci. 2013 Dec 4;8:140. PMID: 24305039 |
| Arnold DM | Thromb Res. | 2013 | Adjudication of bleeding outcomes in an international thromboprophylaxis trial in critical illness. | 23317632 | Arnold DM, Lauzier F, Rabbat C, Zytaruk N, Barlow Cash B, Clarke F, Heels-Ansdell D, Guyatt G, Walter SD, Davies A, Cook DJ; PROTECT Investigators, on behalf of the Canadian Critical Care Trials Group and the Australian and New Zealand Intensive Care Society Clinical Trials Group.Adjudication of bleeding outcomes in an international thromboprophylaxis trial in critical illness.Thromb Res. 2013 Mar;131(3):204-9. PMID: 23317632 |
| Lauzier F | Intensive Care Med | 2013 | Risk factors and impact of major bleeding in critically ill patients receiving heparin thromboprophylaxis. | 23942857 | Lauzier F, Arnold DM, Rabbat C, Heels-Ansdell D, Zarychanski R, Dodek P, Ashley BJ, Albert M, Khwaja K, Ostermann M, Skrobik Y, Fowler R, McIntyre L, Nates JL, Karachi T, Lopes RD, Zytaruk N, Finfer S, Crowther M, Cook D. Risk factors and impact of major bleeding in critically ill patients receiving heparin thromboprophylaxis. Intensive Care Med. 2013;39(12):2135-43. PMID: 23942857 |
| Smith OM | Intensive Crit Care Nurs | 2013 | Enhancing the informed consent process for critical care research: strategies from a thromboprophylaxis trial. | 23871290 | Smith OM, McDonald E, Zytaruk N, Foster D, Matte A, Clarke F, Fleury S, Krause K, McArdle T, Skrobik Y, Cook DJ.Enhancing the informed consent process for critical care research: strategies from a thromboprophylaxis trial. Intensive Crit Care Nurs. 2013;29(6):300-9. PMID: 23871290 |
| Cuthbertson BH | Critical care | 2013 | Clinical stakeholders' opinions on the use of selective decontamination of the digestive tract in critically ill patients in intensive care units: an international Delphi study | 24207137 | Cuthbertson BH, Campbell MK, Maclennan G, Duncan EM, Marshall AP, Wells EC, Prior ME, Todd
L, Rose L, Seppelt IM, Bellingan G, Francis JJ. (2013). Clinical stakeholders' opinions on the use
of selective decontamination of the digestive tract in critically ill patients in intensive care units: an
international Delphi study. Critical care (London, England). 17(6): R266. PMID: 24207137 |
| Dombrowski SU | Aust Crit Care. | 2013 | Clinical components and associated behavioural aspects of a complex healthcare intervention: Multi-methods study of selective decontamination of the digestive tract in critical care. | 23680533 | Dombrowski SU, Prior ME, Duncan E, Cuthbertson BH, Bellingan G, Campbell MK, Rose L, Binning AR, Gordon AC, Wilson P, Shulman R, Francis JJ; the SuDDICU UK Study Group. Clinical components and associated behavioural aspects of a complex healthcare intervention: Multi-methods study of selective decontamination of the digestive tract in critical care. Aust Crit Care. 2013;26(4):173-9. PMID: 23680533 |
| Carson JL | JAMA | 2013 | Outcomes using lower vs higher hemoglobin thresholds for red blood cell transfusion. | 23280228 | Carson JL, Carless PA, Hébert PC.Outcomes using lower vs higher hemoglobin thresholds for red blood cell transfusion. JAMA;309(1):83-4. PMID: 23280228 |
| Karam O | Cochrane Database Syst Rev | 2013 | Plasma transfusion strategies for critically ill patients. | 24374651 | Karam O, Tucci M, Combescure C, Lacroix J, Rimensberger PC. Plasma transfusion strategies for critically ill patients. Cochrane Database Syst Rev. 2013 Dec 28;12:CD010654. PMID: 24374651
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| Karam O | Vox Sang | 2013 | Association between plasma transfusions and clinical outcome in critically ill children: a prospective observational study. | 23294337 | Karam O, Lacroix J, Robitaille N, Rimensberger PC, Tucci M. Association between plasma transfusions and clinical outcome in critically ill children: a prospective observational study. Vox Sang. 2013 May;104(4):342-9. PMID: 23294337 |
| Menon K | Pediatr Crit Care Med. | 2013 | A systematic review and meta-analysis on the effect of steroids in pediatric shock. | 23867428 | Menon K, McNally D, Choong K, Sampson M. A systematic review and meta-analysis on the effect of steroids in pediatric shock.Pediatr Crit Care Med. 2013 Jun;14(5):474-80. doi: 10.1097/PCC.0b013e31828a8125. Review. PMID: 23867428 |
| McNally JD | J Clin Endocrinol Metab. | 2013 | The relationship between vitamin D status and adrenal insufficiency in critically ill children. | 23547046 | McNally JD, Doherty DR, Lawson ML, Al-Dirbashi OY, Chakraborty P, Ramsay T, Menon K. The relationship between vitamin D status and adrenal insufficiency in critically ill children.
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| McMullen S | PLoS ONE | 2012 | Partial Ventilatory Support Modalities in Acute Lung Injury and Acute Respiratory Distress Syndrome – A systematic review | 22916094 | McMullen S, Meade M, Rose L, Mehta S, Burns K, Doyle R and Henzler D for the Canadian Critical Care Trials Group. Partial Ventilatory Support Modalities in Acute Lung Injury and Acute Respiratory Distress Syndrome – A systematic review. PLoS ONE 2012, 7(8): e40190. PMID: 22916094. |
| Dhanani S | J Intensive Care Med | 2012 | Variability in the determination of death after cardiac arrest: a review of guidelines and statements | 21841147 | Dhanani S, Hornby L, Ward R, Shemie S for the Canadian Critical Care Trials Group. Variability in the determination of death after cardiac arrest: a review of guidelines and statements. J Intensive Care Med 2012;27:238-52. PMID: 21841147 |
| Dhanani S | Crit Care Med | 2012 | Survey of determination of death after cardiac arrest by intensive care physicians | 22430244 | Dhanani S, Ward R, Hornby L, Barrowman NJ, Hornby K, Shemie SD for the Canadian Critical Care Trials Group. Survey of determination of death after cardiac arrest by intensive care physicians. Crit Care Med 2012;40:1449-55. PMID: 22430244 |
| Côte N | Neurocrit Care | 2012 | Factors Associated with the Withdrawal of Life-Sustaining Therapies in Patients with Severe Traumatic Brain Injury: A Multicenter Cohort Study | 23099846 | Côte N, Turgeon AF, Lauzier F, Moore L, Scales DC, Bernard F, Zarychanski R, Burns KE, Meade MO, Zygun D, Simard JF, Boutin A, Brochu JG, Fergusson DA for the Canadian Critical Care Trials Group. Factors Associated with the Withdrawal of Life-Sustaining Therapies in Patients with Severe Traumatic Brain Injury: A Multicenter Cohort Study. Neurocrit Care. 2012 Oct 26. [Epub ahead of print] PMID: 23099846 |
| Wald R | Crit Care | 2012 | Optimal Mode of clearance in critically ill patients with Acute Kidney Injury (OMAKI) - a pilot randomized controlled trial of hemofiltration versus hemodialysist | 23095370 | Wald R, Friedrich JO, Bagshaw SM, Burns KE, Garg AX, Hladunewich MA, House AA, Lapinsky S, Klein D, Pannu NI, Pope K, Richardson RM, Thorpe K, Adhikari NK for the Canadian Critical Care Trials Group. Optimal Mode of clearance in critically ill patients with Acute Kidney Injury (OMAKI) - a pilot randomized controlled trial of hemofiltration versus hemodialysist. Crit Care. 2012 Oct 24;16(5):R205. [Epub ahead of print] PMID: 23095370. |
| McIntyre L | Transfus Med Rev | 2012 | The PRECISE RCT: Evolution of an early septic shock fluid resuscitation tria | 22222146 | McIntyre L, Fergusson DA, Rowe B, Cook DJ, Arabi Y, Bagshaw S, Emond M, Finfer S Fox-Robichaud A, Gray A, Green R, Hebert P, Lang E, Marshall J, Stiell I, Tinmouth A, Pagliarello J, Turgeon A, Walsh T, Worster A, Zarychanski R for the Canadian Critical Care Trials Group: The PRECISE RCT: Evolution of an early septic shock fluid resuscitation trial. Transfus Med Rev. 2012 Oct;26(4):333-341. Epub 2012 Jan 4. PMID: 22222146 |
| Friedrich JO | Crit Care | 2012 | Hemofiltration compared to hemodialysis for acute kidney injury: systematic review and meta-analysis | 22867021 | Friedrich JO, Wald R, Bagshaw SM, Burns KE, Adhikari NK for the Canadian Critical Care Trials Group. Hemofiltration compared to hemodialysis for acute kidney injury: systematic review and meta-analysis. Crit Care. 2012 Aug 6;16(4):R146. [Epub ahead of print] PMID: 22867021 |
| McIntyre LL | J Crit Care | 2012 | Fluid Resuscitation with 5% Albumin versus Normal Saline in Early Septic Shock (PRECISE): A Pilot Randomized Controlled Tria | 22176806 | McIntyre LL, Fergusson DA, Cook DJ, Rowe B, Bagshaw S, Easton D, Edmond M, Finfer S, Fox-Robichaud A, Green R, Hebert P, Marshall J, Rankin N, Stiell I, Tinmouth A, Pagliarello J, Turgeon A, Worster A, Zarychanski R for the Canadian Critical Care Trials Group. Fluid Resuscitation with 5% Albumin versus Normal Saline in Early Septic Shock (PRECISE): A Pilot Randomized Controlled Trial. J Crit Care. 2012 Jun;27(3):317.e1-6. Epub 2011 Dec 15. PMID: 22176806 |
| Muscedere J | J Crit Care | 2012 | The adequacy of timely empiric antibiotic therapy for ventilator-associated pneumonia: an important determinant of outcome | 22137378 | Muscedere J., Shorr A.F., Jiang X., Day A., Heyland DK on behalf of the Canadian Critical Care Trials Group. The adequacy of timely empiric antibiotic therapy for ventilator-associated pneumonia: an important determinant of outcome. J Crit Care. 2012 Jun;27(3):322.e7-14. Epub 2011 Dec 1. PMID: 22137378 |
| Cahill NE | J Crit Care | 2012 | Barriers to feeding critically ill patients: a multicenter survey of critical care nurses | 22981532 | Cahill NE, Murch L, Cook D, Heyland DK; Canadian Critical Care Trials Group. Barriers to feeding critically ill patients: a multicenter survey of critical care nurses. J Crit Care. 2012 Dec;27(6):727-34. PMID: 22981532 |
| Kanji S | J Crit Care | 2012 | Epidemiology and management of atrial fibrillation in medical and noncardiac surgical adult intensive care unit patients | 22226423 | Kanji S, Williamson DR, Yaghchi BM, Albert M, McIntyre L, On behalf of the Canadian Critical Care Trials Group. J Epidemiology and management of atrial fibrillation in medical and noncardiac surgical adult intensive care unit patients. J Crit Care. 2012 Jun;27(3):326.e1-8. Epub 2012 Jan 4. PMID: 22226423 |
| Dodek PM | Am J Respir Crit Care Med 185 | 2012 | Evaluation of an Internal Review Process for Grants and Manuscripts at the Canadian Critical Care Trials Group | | Dodek PM, Caon E, Burns K, On behalf of the Canadian Critical Care Trials Group. Evaluation of an Internal Review Process for Grants and Manuscripts at the Canadian Critical Care Trials Group. Am J Respir Crit Care Med 185;2012:A2542. |
| McNally D | Pediatrics | 2012 | The Association of Vitamin D Status with Pediatric Critical Illness | 22869837 | McNally D, Menon K, Williams K, Chakraborty P, Doherty D for the Canadian Critical Care Trials Group. Vitamin D Status in Pediatric Critical Illness. Pediatrics. 2012;130(3):429-36. PMID:22869837 |
| Lutz K | J Crit Care | 2012 | Research Ethics Board Approval. For An International Thromboprophylaxis Trial | 22305662 | Lutz K, Wilton K, Zytaruk N, Julien L, Hall R, Harvey J, Skrobik Y, Vlahakis N, Meade L, Matte A, Meade M, Burns KB, Albert M, Barlow Cash B, Vallance S, Klinger J, Heels-Ansdell D, Cook D, for the PROTECT Investigators in collaboration with the Canadian Critical Care Trials Group and ANZICS-CTG. Research Ethics Board Approval. For An International Thromboprophylaxis Trial. J Crit Care. 2012;27(3):225-31. PMID:22305662 |
| Turgeon AF | Crit Care Med | 2012 | Determination of neurological prognosis in adult patients with severe traumatic brain injury: a survey of Canadian intensivists, neurosurgeons and neurologists | | Turgeon AF, Lauzier F, Burns K, Fergusson DA, Zygun D, Meade M, Scales D, Zarychanski R, McIntyre L, Kanji S, Pagliarello J, Hébert P for the Canadian Critical Care Trials Group. Determination of neurological prognosis in adult patients with severe traumatic brain injury: a survey of Canadian intensivists, neurosurgeons and neurologists. Crit Care Med 2012; (in press). |
| Mehta S | JAMA | 2012 | A randomized trial of daily sedation interruption in mechanically ventilated critically ill patients cared for with a sedation protocol | 23180503 | Mehta S, Burry L, Cook D, Fergusson D, Steinberg M, Granton J, Herridge M, Ferguson N, Devlin J, Tanios M, Dodek P, Fowler R, Burns K, Jacka M, Olafson K, Skrobik Y, Hebert P, Sabri E, and Meade M, for the SLEAP Investigators and the Canadian Critical Care Trials Group. A randomized trial of daily sedation interruption in mechanically ventilated critically ill patients cared for with a sedation protocol. JAMA. 2012;308(19):1985-92. PMID: 23180503 |
| Menon K | Int Care Med | 2012 | Understanding the Consent Process in Pediatric Critical Care Research | | Menon K, Ward R, Gaboury I, Thomas M, Joffe A, Burns K, Cook D for the Canadian Critical Care Trials Group. Understanding the Consent Process in Pediatric Critical Care Research. Int Care Med. Volume 38, Issue 1 (2012), Page 153-159. |
| Potter BJ | J Crit Care | 2012 | Cardiac output responses in a flow-driven protocol of resuscitation following cardiac surgery. | 23159133 | Potter BJ, Deverenne B, Doucette S, Fergusson D, Magder S; for the Canadian Critical Care Trials Group. Cardiac output responses in a flow-driven protocol of resuscitation following cardiac surgery. J Crit Care. 2013 Jun;28(3):265-9. Epub 2012 Nov 14. PMID: 23159133. |
| L Rose | Crit Care Med | 2012 | Sleep, cognitive and psychological morbidity following sedation protocol and daily sedative interruption vs sedation protocol alone in critically ill, mechanically ventilated adults (SLEAP-SCP) | | L Rose, R Maunder, J Hunter, A Day, M Steinberg, M Herridge, J Devlin, P Dodek, L Burry, S Mehta, for the Canadian Critical Care Trials Group. Sleep, cognitive and psychological morbidity following sedation protocol and daily sedative interruption vs sedation protocol alone in critically ill, mechanically ventilated adults (SLEAP-SCP). Crit Care Med 2012; 40 (12 Suppl.): Abstract 1104 |
| The NICE-SUGAR Study Investigators | N Engl J Med | 2012 | Hypoglycemia and risk of death in critically ill patients. | 22992074 | NICE-SUGAR Study Investigators, Finfer S, Liu B, Chittock DR, Norton R, Myburgh JA, McArthur C, Mitchell I, Foster D, Dhingra V, Henderson WR, Ronco JJ, Bellomo R, Cook D, McDonald E, Dodek P, Hébert PC, Heyland DK, Robinson BG.Hypoglycemia and risk of death in critically ill patients.N Engl J Med. 2012 Sep 20;367(12):1108-18. PMID: 22992074 |
| Carson JL | Cochrane Database Syst Rev. | 2012 | Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion. | 22513904 | Carson JL, Carless PA, Hebert PC. Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion. Cochrane Database Syst Rev. 2012;4. PMID: 22513904 |
| Desjardins D | Crit Care | 2012 | Hemoglobin levels and transfusion in neurocritically ill patients: a systematic review of comparative studies | 22471943 | Desjardins *, Turgeon AF, Tremblay MH, Lauzier F, Zarychanski R, Moore L, McIntyre L, English S, Boutin A, Lacroix J, Fergusson DA. Hemoglobin levels and transfusion in neurocritically ill patients: a systematic review of comparative studies. Crit Care 2012;Apr 2;16(2):R54. PMID: 22471943 |
| Clark E | Can J Anaesth. | 2012 | Timing the initiation of renal replacement therapy for acute kidney injury in Canadian intensive care units: a multicentre observational study. | 22752716 | Clark E, Wald R, Levin A, Bouchard J, Adhikari NK, Hladunewich M, Richardson RM, James MT, Walsh MW, House AA, Moist L, Stollery DE, Burns KE, Friedrich JO, Barton J, Lafrance JP, Pannu N, Bagshaw SM; Canadian Acute Kidney Injury (CANAKI) Investigators. Timing the initiation of renal replacement therapy for acute kidney injury in Canadian intensive care units: a multicentre observational study.
Can J Anaesth. 2012 Sep;59(9):861-70. PMID: 22752716 |
| Bagshaw SM | J Crit Care | 2012 | Clinical factors associated with initiation of renal replacement therapy in critically ill patients with acute kidney injury-a prospective multicenter observational stud | 21798709 | Bagshaw SM, Wald R, Barton J, Burns KE, Friedrich JO, House AA, James MT, Levin A, Moist L, Pannu N, Stollery DE, Walsh MW. Clinical factors associated with initiation of renal replacement therapy in critically ill patients with acute kidney injury-a prospective multicenter observational study.
J Crit Care. 2012 Jun;27(3):268-75. PMID: 21798709 |
| Clark E | Nephrol Dial Transplant. | 2012 | Timing of initiation of renal replacement therapy for acute kidney injury: a survey of nephrologists and intensivists in Canada. | 22207332 | Clark E, Wald R, Walsh M, Bagshaw SM; Canadian Acute Kidney Injury (CANAKI) Investigators. Timing of initiation of renal replacement therapy for acute kidney injury: a survey of nephrologists and intensivists in Canada.
Nephrol Dial Transplant. 2012 Jul;27(7):2761-7. PMID: 22207332 |
| Dwivedi DJ | Journal of Critical Care | 2012 | Prognostic utility and characterization of cell-free DNA in patients with severe sepsis | | Dwivedi DJ, Toltl LJ, Swystun LL, Pogue J, Liaw KL, Weitz JI, Cook DJ, Fox-Robichaud AE, Liaw PC and Canadian Critical Care Translational Biology Group. Prognostic utility and characterization of cell-free DNA in patients with severe sepsis. Critical Care 2012, 16:R151.
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| Safiah Mai | InTech | 2012 | Experimental Sepsis Models, Sepsis - An Ongoing and Significant Challenge | | Safiah Mai, Momina Khan, Patricia Liaw and Alison Fox-Robichaud (2012). Experimental Sepsis Models, Sepsis - An Ongoing and Significant Challenge, Luciano Azevedo (Ed.), ISBN: 978-953-51-0780-4, InTech, Available from:
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| Lamontagne F | J Crit Care | 2011 | Vasopressor administration and sepsis: a survey of Canadian intensivists | 21454040 | Lamontagne F, Cook DJ, Adhikari NK, Briel M, Duffett M, Kho ME, Burns KE, Guyatt G, Turgeon AF, Zhou Q, Meade MO for the Canadian Critical Care Trials Group. Vasopressor administration and sepsis: a survey of Canadian intensivists. J Crit Care. 2011 Oct;26(5):532.e1-7. Epub 2011 Mar 30. PMID: 21454040 |
| Duffett M | J Crit Care | 2011 | Consent in critical care trials: a survey of Canadian research ethics boards and critical care researchers | 21376518 | Duffett M, Burns KEA, Kho M, Lauzier L, Meade M,, Arnold D, Adhikari N, Lamontagne L, Cook DJ for ACCADEMY and for the Canadian Critical Care Trials Group. Consent in critical care trials: a survey of Canadian research ethics boards and critical care researchers. J Crit Care. 2011;26(5):533. PMID: 21376518 |
| Parshuram C | Critical Care | 2011 | Multi-centre validation of the Bedside Paediatric Early Warning System Score: A severity of illness score to detect evolving critical illness in hospitalized children | 21812993 | Parshuram C, Duncan H, Joffe A, Farrell C, Lacroix J, Middaugh K, Hutchison JS, Wensley D, Beyene J, Parkin P, for the Canadian Critical Care Trials Group. Multi-centre validation of the Bedside Paediatric Early Warning System Score: A severity of illness score to detect evolving critical illness in hospitalized children. Critical Care 2011 Aug 3;15(4):R184. PMID: 21812993 |
| Adhikari NK | Crit Care Med | 2011 | High frequency oscillation in adults: a utilization review | 21765359 | Adhikari NK, Bashir A, Lamontagne F, Mehta S, Ferguson ND, Zhou Q, Hand L, Czarnecka K, Cook DJ, Granton JT, Friedrich JO, Freitag A, Watpool I, Meade MO for the Canadian Critical Care Trials Group. High frequency oscillation in adults: a utilization review. Crit Care Med. 2011 Dec;39(12):2631-44. PMID: 21765359 |
| Katsios C | Crit Care | 2011 | Red blood cell transfusion and increased length of storage are not associated with deep vein thrombosis in medical-surgical critically ill patients: a prospective observational cohort study | 22044745 | Katsios C, Griffith L, Spinella P, Lacroix J, Crowther M, Hebert P, Meade M, Geerts W, Rabbat C, Cook D for the Canadian Critical Care Trials Group. Red blood cell transfusion and increased length of storage are not associated with deep vein thrombosis in medical-surgical critically ill patients: a prospective observational cohort study. Crit Care 2011; 15:R263. PMID: 22044745 |
| The PROTECT | N Engl J Med | 2011 | A Randomized Trial of Dalteparin versus Unfractionated Heparin in Critically Ill Patients | 21417952 | The PROTECT Investigators for the Canadian Critical Care Trials Group & the Australian and New Zealand Intensive Care Society Clinical Trials Group. A Randomized Trial of Dalteparin versus Unfractionated Heparin in Critically Ill Patients. N Engl J Med 2011;364(14):1305-1314. PMID: 21417952 |
| Cook DJ | J Crit Care | 2011 | PROTECT (Prophylaxis for ThromboEmbolism in Critical Care Trial) Protocol and Analysis Plan | 21482348 | Cook DJ, Meade M, Guyatt G, Walter SD, Heels-Ansdell D, Geerts W, Warkentin T, Cooper DJ, Zytaruk N, Vallance S, Berwanger O, Rocha M, Qushmaq I, Crowther MA for the PROTECT Investigators, for the Canadian Critical Care Trials Group and the Australian and New Zealand Intensive Care Society Clinical Trials Group. PROTECT (Prophylaxis for ThromboEmbolism in Critical Care Trial) Protocol and Analysis Plan. J Crit Care 2011;26(2); e223.e9 & doi:10.1016/j.jcrc.2011.02.010) PMID: 21482348 |
| Turgeon AF | CMAJ | 2011 | Mortality associated with withdrawal of life-sustaining therapy for patients with severe traumatic brain injury: a Canadian multicentre cohort study | 21876014 | Turgeon AF, Lauzier F, Simard JF, Scales DC, Burns KEA, Moore L, Zygun DA, Bernard F, Meade MO, Dung TC, Ratnapalan M, Todd S, Harlock J, Fergusson DA for the Canadian Critical Care Trials Group. Mortality associated with withdrawal of life-sustaining therapy for patients with severe traumatic brain injury: a Canadian multicentre cohort study. CMAJ October 4, 2011 vol. 183 no. 14 First published August 29, 2011. PMID: 21876014 |
| Karam O | Pediatr Crit Care Med | 2011 | Red blood cell transfusion thresholds in pediatric patients with sepsis | 21057356 | Karam O, Tucci M, Ducruet T, Hume HA, Lacroix J, Gauvin F; for the Canadian Critical Care Trials Group and the PALISI Network. Red blood cell transfusion thresholds in pediatric patients with sepsis. Pediatr Crit Care Med. 2011 Sep;12(5):512-518. PMID: 21057356 |
| Sud S | Am J Respir Crit Care Med | 2011 | Screening and Prevention of Venous Thromboembolism in Critically Ill Patients: A Decision Analysis and Economic Evaluation | 21868500 | Sud S, Mittmann N, Cook DJ, Geerts W, Chan B, Dodek P, Gould MK, Guyatt G, Arabi Y, Fowler RA; On Behalf of the E-PROTECT Investigators and for the Canadian Critical Care Trials Group. Screening and Prevention of Venous Thromboembolism in Critically Ill Patients: A Decision Analysis and Economic Evaluation. Am J Respir Crit Care Med. 2011 Aug 25. [Epub ahead of print] PMID: 21868500 |
| Lacroix J | Transfusion Medicine Reviews | 2011 | The age of blood evaluation (ABLE) randomized controlled trial: Study design | 21550205 | Lacroix J, Hébert PC, Fergusson D, Tinmouth A, Blajchman MA, Callum J, Cook D, Marshall J, McIntyre L, Turgeon A, for the ABLE study group, and for the Canadian Critical Care Trials Group. The age of blood evaluation (ABLE) randomized controlled trial: Study design. Transfusion Medicine Reviews 2011;25:197-205. PMID: 21550205 |
| Herridge MS | N Engl J Med | 2011 | Functional disability 5 years after acute respiratory distress syndrome | 21470008 | Herridge MS, Tansey CM, Matté A, Tomlinson G, Diaz-Granados N, Cooper A, Guest CB, Mazer CD, Mehta S, Stewart TE, Kudlow P, Cook D, Slutsky AS, Cheung AM; for the Canadian Critical Care Trials Group. Functional disability 5 years after acute respiratory distress syndrome. N Engl J Med. 2011 Apr 7;364(14):1293-304. PMID: 21470008 |
| Burns KE | Trials | 2011 | A Canadian Critical Care Trials Group project in collaboration with the international forum for acute care trialists - Collaborative H1N1 Adjuvant Treatment pilot trial (CHAT): study protocol and design of a randomized controlled trial | 21388549 | Burns KE, Chant C, Smith O, Cuthbertson B, Fowler R, Cook DJ, Kruger P, Webb S, Alhashemi J, Dominguez-Cherit G, Zala C, Rubenfeld GD, Marshall JC for the Canadian Critical Care Trials Group. A Canadian Critical Care Trials Group project in collaboration with the international forum for acute care trialists - Collaborative H1N1 Adjuvant Treatment pilot trial (CHAT): study protocol and design of a randomized controlled trial. Trials. 2011 Mar 9;12:70. PMID: 21388549 |
| Heyland DK | Crit Care | 2011 | Persistent organ dysfunction plus death: a novel, composite outcome measure for critical care trials | 21418560 | Heyland DK, Muscedere J, Drover J, Jiang X, Day AG for the Canadian Critical Care Trials Group. Persistent organ dysfunction plus death: a novel, composite outcome measure for critical care trials. Crit Care. 2011;15(2):R98. Epub 2011 Mar 18. PMID: 21418560 |
| Keenan SP | Can Med Assoc J | 2011 | Clinical practice guidelines for noninvasive positive pressure ventilation (NPPV) and noninvasive continuous positive airway pressure (nCPAP) in the acute care setting | 21324867 | Keenan SP, Sinuff T, Burns K, Muscedere J, Kutsogiannis J, Sangeeta M, Dodek P, Cook DJ, Ayas N, Adhikari N, Hand L, Scales D, Pagnotta R, Lazosky L, Rocker G, Dial S, Laupland K, Sanders K for the Canadian Critical Care Trials Group and Canadian Critical Care Society. Noninvasive Ventilation Guidelines Group. Clinical practice guidelines for noninvasive positive pressure ventilation (NPPV) and noninvasive continuous positive airway pressure (nCPAP) in the acute care setting. Can Med Assoc J 2011 Feb 22;183(3):E195-214. Epub 2011 Feb 14. PMID: 21324867 |
| Ethier C | J of Crit Care | 2011 | Recall of ICU stay in patients managed with a Sedation Protocol or a Sedation Protocol with Daily Sedative Interruption: A Pilot Study | 20889289 | Ethier C, Burry L, Martinez-Motta C, Tirgari S, Jiang D, McDonald E, Granton J, Cook D, Mehta S, for the Canadian Critical Care Trials Group. Recall of ICU stay in patients managed with a Sedation Protocol or a Sedation Protocol with Daily Sedative Interruption: A Pilot Study. J of Crit Care 2011;26:127-132. Epub Oct 1, 2010. PMID: 20889289 |
| Delisle MS | Can Respir J | 2011 | Impact of Candida species on clinical outcomes in patients with suspected ventilator-associated pneumonia. | 21766075 | Delisle MS, Williamson DR, Albert M, Perreault MM, Jiang X, Day AG, Heyland DK. Impact of Candida species on clinical outcomes in patients with suspected ventilator-associated pneumonia. Can Respir J. 2011;18(3):131-6. PMID: 21766075 |
| Williamson DR | Can J Anaesth. | 2011 | The relationship between Candida species cultured from the respiratory tract and systemic inflammation in critically ill patients with ventilator-associated pneumonia. | 2128730 | Williamson DR, Albert M, Perreault MM, Delisle MS, Muscedere J, Rotstein C, Jiang X, Heyland DK. The relationship between Candida species cultured from the respiratory tract and systemic inflammation in critically ill patients with ventilator-associated pneumonia. Can J Anaesth. 2011;58(3):275-84. PMID: 2128730 |
| Fraser DD | Pediatr Crit Care Med | 2011 | Severe traumatic brain injury in children elevates glial fibrillary acidic protein in cerebrospinal fluid and serum | 20625342 | Fraser DD, Close TE, Rose KL, Ward R, Mehl M, Farrell C, Lacroix J, Creery D, Kesselman M, Stanimirovic D, Hutchison JS, for the Canadian Critical Care Translational Biology Group. Severe traumatic brain injury in children elevates glial fibrillary acidic protein in cerebrospinal fluid and serum. Pediatr Crit Care Med 2011;12:319-24. PMID: 20625342 |
| Stiff D | Pediatr Crit Care Med | 2011 | Potential pediatric intensive care unit demand/capacity mismatch due to novel pH1N1 in Canada. | 20473239 | Stiff D1, Kumar A, Kissoon N, Fowler R, Jouvet P, Skippen P, Smetanin P, Kesselman M, Veroukis S. Potential pediatric intensive care unit demand/capacity mismatch due to novel pH1N1 in Canada. Pediatr Crit Care Med. 2011 Mar;12(2):e51-7. PMID: 20473239
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| Karvellas CJ | Crit Care | 2011 | A comparison of early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury: a systematic review and meta-analysis. | 21352532 | Karvellas CJ, Farhat MR, Sajjad I, Mogensen SS, Leung AA, Wald R, Bagshaw SM. A comparison of early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury: a systematic review and meta-analysis. Crit Care. 2011;15(1):R72. PMID: 21352532 |
| Daneman N | Int J Antimicrob Agents | 2011 | Antibiotic treatment duration for bloodstream infections in critically ill patients: a national survey of Canadian infectious diseases and critical care specialists. | 21982833 | Daneman N, Shore K, Pinto R, Fowler R.. Antibiotic treatment duration for bloodstream infections in critically ill patients: a national survey of Canadian infectious diseases and critical care specialists.Int J Antimicrob Agents. 2011 Dec;38(6):480-5. PMID: 21982833
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| Havey TC | Crit Care | 2011 | Duration of antibiotic therapy for bacteremia: a systematic review and meta-analysis. | 22085732 | Havey TC, Fowler RA, Daneman N.Duration of antibiotic therapy for bacteremia: a systematic review and meta-analysis. Crit Care. 2011;15(6):R267. PMID: 22085732 |
| Gauvin F | Transfusion | 2010 | Association between length of storage of transfused red blood cells and multiple organ dysfunction syndrome in pediatric intensive care patients | 20456697 | Gauvin F, Spinella PC, Lacroix J, Choker G, Ducruet T, Karam O, Hébert PC, Hutchison JS, Hume HA, Tucci M, on behalf of the Canadian Critical Care Trials Group and the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. Association between length of storage of transfused red blood cells and multiple organ dysfunction syndrome in pediatric intensive care patients. Transfusion. 2010 Sep;50(9):1902-13 PMID: 20456697 |
| Rouette J | Annals of Surgery | 2010 | Red blood cell transfusion threshold in post-surgical pediatric intensive care patients: a randomized clinical trial | 20118780 | Rouette J, Trottier H, Ducruet T, Beaunoyer M, Lacroix J, Tucci M for the Canadian Critical Care Trials Group and PALISI. Red blood cell transfusion threshold in post-surgical pediatric intensive care patients: a randomized clinical trial. Annals of Surgery 2010; 251:421-7. PMID: 20118780 |
| Willems A | Crit Care Med | 2010 | Comparison of two red-cell transfusion strategies after pediatric cardiac surgery: a subgroup analysis | 19789443 | Willems A, Harrington K, Lacroix J, Biarent D, Joffe ARI, Wensley D, Ducruet T, Hébert PC, Tucci M, on behalf of the TRIPICU investigators, for the Canadian Critical Care Trials Group and the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. Comparison of two red-cell transfusion strategies after pediatric cardiac surgery: a subgroup analysis. Crit Care Med 2010;38(2):649-56. PMID: 19789443 |
| Hutchison JS | Dev Neurosci | 2010 | Impact of hypotension and low cerebral perfusion pressure on outcomes in children treated with hypothermia therapy following severe traumatic brain injury: A post hoc analysis of the hypothermia pediatric head injury trial | 21252486 | Hutchison JS, Frndova H, Lo TY, Guerguerian AM for the Hypothermia Pediatric Head Injury Trial Investigators and for the Canadian Critical Care Trials Group. Impact of hypotension and low cerebral perfusion pressure on outcomes in children treated with hypothermia therapy following severe traumatic brain injury: A post hoc analysis of the hypothermia pediatric head injury trial. Dev Neurosci 2010;32:406-412. PMID: 21252486 |
| Freed DH | Can J Anaesth | 2010 | Extracorporeal lung support for patients who had severe respiratory failure secondary to influenza A (H1N1) 2009 infection in Canada | 20082167 | Freed DH, Henzler D, White CW, Fowler R, Zarychanski R, Hutchison J, Arora RC, Manji RA, Legare JF, Drews T, Veroukis S, Kesselman M, Guerguerian AM, Kumar A; for the Canadian Critical Care Trials Group. Extracorporeal lung support for patients who had severe respiratory failure secondary to influenza A (H1N1) 2009 infection in Canada. Can J Anaesth 2010;57(3):240-7. PMID: 20082167 |
| Jouvet P | Pediatr Crit Care Med | 2010 | Critical illness in children with influenza A/pH1N1 2009 infection in Canada | 20308929 | Jouvet P, Hutchison J, Pinto R, Menon K, Rodin R, Choong K, Kesselman M, Veroukis S, André Dugas M, Santschi M, Guerguerian AM, Withington D, Alsaati B, Joffe AR, Drews T, Skippen P, Rolland E, Kumar A, Fowler RA, for the Canadian Critical Care Trials Group H1N1 Collaborative. Critical illness in children with influenza A/pH1N1 2009 infection in Canada. Pediatr Crit Care Med. 2010 Sep;11(5):603-9. PMID: 20308929 |
| Menon K | Am J Respir Crit Care Med | 2010 | A Prospective Multi-Center Study of Adrenal Function in Critically Ill Children | 20299532 | Menon K, Ward RE, Lawson ML, Gaboury I, Hutchison JS, Hébert PC, and for the Canadian Critical Care Trials Group. A Prospective Multi-Center Study of Adrenal Function in Critically Ill Children. Am J Respir Crit Care Med. 2010 Jul 15;182(2):246-51. Epub 2010 Mar 18. PMID: 20299532 |
| Crowther MA | J Crit Care | 2010 | The 4Ts scoring system for heparin induced thrombocytopenia in medical-surgical ICU patients | 20149589 | Crowther MA, Cook DJ, Albert M, Williamson D, Meade M, Granton J, Skrobik Y, Langevin S, Mehta S, Hebert PC, Guyatt GH, Geerts W, Rabbat C, Douketis J, Zytaruk N, Sheppard J, Greinacher A, Warkentin TE for the Canadian Critical Care Trials Group. The 4Ts scoring system for heparin induced thrombocytopenia in medical-surgical ICU patients. J Crit Care 2010; 25(2):287-293. doi:10.1016/j.jcrc.2009.12.006 PMID: 20149589 |
| Fraser DD | Pediatr Crit Care Med | 2010 | Severe traumatic brain injury in children elevates glial fibrillary acidic protein in cerebrospinal fluid and serum | | Severe traumatic brain injury in children elevates glial fibrillary acidic protein in cerebrospinal fluid and serum. Fraser DD, Close TE, Rose KL, Ward R, Mehl M, Farrell C, Lacroix J, Creery D, Kesselman M, Stanimirovic D, Hutchison JS; for the Canadian Critical Care Translational Biology Group. Pediatr Crit Care Med. 2010 Jul 9. [Epub ahead of print]
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| Yazdan-Ashoori P | Journal of Critical Care | 2010 | Elevated plasma matrix metalloproteinases and their tissue inhibitors in patients with severe sepsis | | Yazdan-Ashoori P, Liaw P, Toltl L, Webb B, Kilmer G, Carter D, Fraser DD (2011) Elevated plasma matrix metalloproteinases and their tissue inhibitors in patients with severe sepsis. Journal of Critical Care. Mar 23 [Epub ahead of print].
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| Menon K | Am J Respir Crit Care Med. | 2010 | A prospective multicenter study of adrenal function in critically ill children. | 20299532 | Menon K, Ward RE, Lawson ML, Gaboury I, Hutchison JS, Hébert PC; Canadian Critical Care Trials Group.
A prospective multicenter study of adrenal function in critically ill children. Am J Respir Crit Care Med. 2010 Jul 15;182(2):246-51. PMID: 20299532 |
| Choong K | Am J Respir Crit Care Med | 2009 | Vasopressin in Pediatric Vasodilatory Shock - A Multi-center Randomized Controlled Trial | 19608718 | Choong K, Bohn D, Fraser DD, Gaboury I, Hutchison JS, Joffe AR, Litalien C, Menon K, McNamara P, Ward RB with the Canadian Critical Care Trials Group. Vasopressin in Pediatric Vasodilatory Shock - A Multi-center Randomized Controlled Trial. Am J Respir Crit Care Med 2009;180(7)632-9. PMID: 19608718 |
| Burns KE | Trials | 2009 | The WEAN Study: a protocol of a multicenter randomized controlled trial | 2749823 | Burns KE, Meade MO, Lessard M, Keenan SP, Lelouche F for the Canadian Critical Care Trials Group. Wean Earlier and Automatically with New Technology: The WEAN Study: a protocol of a multicenter randomized controlled trial. Trials 2009;10:81. PMCID: PMC2749823 |
| Kumar A | JAMA | 2009 | Critically Ill Patients with Novel Swine Origin Influenza Virus A/H1N1 Infection in Canada | 19822627 | Kumar A, Zarychanski R, Pinto R, Cook DJ, Marshall J, Lacroix J, Stelfox T, Bagshaw S, Choong K, Lamontagne F, Turgeon A, Lapinsky S, Ahern SP, Smith O, Siddiqui F, Jouvet J, Khwaja K, McIntyre L, Menon K, Hutchison J, Hornstein D, Joffe A, Lauzier F, Singh J, Karachi T, Wiebe K, Olafson K, Ramsey C, Sharma S, Dodek P, Meade M, Hall R, Fowler R for the Canadian Critical Care Trials Group H1N1 Collaborative. Critically Ill Patients with Novel Swine Origin Influenza Virus A/H1N1 Infection in Canada JAMA 2009; 302(17):1872-1879. PMID: 19822627 |
| Henderson W | Pol Arch Med Wewn | 2009 | The efficacy and Safety of Glucose Control Algorithms in Intensive Care: A Pilot Study of the Survival using Glucose Algorithm Regulation Trial (SUGAR) | 19776683 | Henderson W, Dhingra V, Chittock D, Foster D, Hebert P, Cook DJ, Heyland D, Dodek P, Schulzer M, Ronco R in association with the Canadian Critical Care Trials Group. The efficacy and Safety of Glucose Control Algorithms in Intensive Care: A Pilot Study of the Survival using Glucose Algorithm Regulation Trial (SUGAR). Pol Arch Med Wewn 2009 Jul-Aug;119(7-8):439-46. PMID: 19776683 |
| Doherty DR | Circulation | 2009 | Hypothermia Therapy after Pediatric Cardio-respiratory Arres | 19273725 | Doherty DR, Parshuram CS, Aparna Hoskote A, Lacroix J, Tucci M, Joffe A, Choong K, Gaboury I, Farrell R, Bohn DJ, Hutchison J, on behalf of the Canadian Critical Care Trials Group. Hypothermia Therapy after Pediatric Cardio-respiratory Arrest. Circulation 2009;119:1492-1500. PMID: 19273725 |
| Scales DC | Intensive Care Med | 2009 | Patients’ Preferences For Enrolment into Critical Care Trials | 19551372 | Scales DC, Orla M. Smith OM, Pinto R, Barrett KA, Friedrich JO, Lazar NM, Cook DJ, Ferguson ND for the Canadian Critical Care Trials Group. Patients’ Preferences For Enrolment into Critical Care Trials. Intensive Care Med. 2009 Oct;35(10):1703-12. Epub 2009 Jun 24. PMID: 19551372 |
| The NICE SUGAR Study Investigators | N Engl J Med | 2009 | Intensive versus conventional glucose control in critically ill patients | 19318384 | The NICE SUGAR Study Investigators for the Australian and New Zealand Intensive Care Society, the George Institute for International Health, for the Canadian Critical Care Trials Group, and the Vancouver Coastal Health Research Institute . Intensive versus conventional glucose control in critically ill patients. N Engl J Med 2009;360(13):1283-1297. PMID: 19318384 |
| Marshall JC | Crit Care Med | 2009 | Investigator-led clinical research consortia: The Canadian Critical Care Trials Group | 19104219 | Marshall JC, Cook DJ for the Canadian Critical Care Trials Group. Investigator-led clinical research consortia: The Canadian Critical Care Trials Group. Crit Care Med 2009; 36(7):S165-S172. PMID: 19104219 |
| Cook D | J Crit Care | 2009 | Event adjudication and data monitoring in an intensive care unit observational study of thromboprophylaxis. | 19327956 | Cook D, Sinuff T, Zytaruk N, Rabbat C, Lee A, O'Donnell M, Thabane L, Linkins L, Treleaven D, Patel R, Meade M, Crowther M, Marshall JC, Douketis J; DIRECT Investigators and Canadian Critical Care Trials Group. Event adjudication and data monitoring in an intensive care unit observational study of thromboprophylaxis.J Crit Care. 2009;24(2):168-75. PMID: 19327956 |
| Scales DC | J Crit Care | 2009 | Prophylaxis against venous thromboembolism in neurointensive care patients: survey of Canadian practice. | 19501306 | Scales DC, Riva-Cambrin J, Le TL, Pinto R, Cook DJ, Granton JT; Canadian Critical Care Trials Group.J
Prophylaxis against venous thromboembolism in neurointensive care patients: survey of Canadian practice. Crit Care. 2009 Jun;24(2):176-84. PMID: 19501306 |
| Karam O | Transfusion | 2009 | Length of storage and in vitro immunomodulation induced by prestorage leukoreduced red blood cells | 19624600 | Karam O, Tucci M, Toledano BJ, Robitaille N, Cousineau J, Thibault L, Lacroix J, Le Deist F. Length of storage and in vitro immunomodulation induced by prestorage leukoreduced red blood cells. Transfusion. 2009;49(11):2326-34. PMID: 19624600
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| McIntyre LA | Can J Anesth | 2008 | Fluid Resuscitation in the Management of Early Septic Shock (FINESS): A pilot randomized controlled feasibility study | 19050085 | McIntyre LA, Fergusson D, Cook DJ, Rankin N, Dhingra V, Granton J, Magder S, Taljjard M, Hebert PC for the Canadian Critical Care Trials Group. Fluid Resuscitation in the Management of Early Septic Shock (FINESS): A pilot randomized controlled feasibility study Can J Anesth 2008, 55: 12; 819-826. PMID: 19050085 |
| Douketis J | Arch Intern Med | 2008 | Renal Insufficiency with the Low-molecular-weight Heparin Dalteparin: An Assessment of Safety and Pharmacodynamics. The DIRECT (Dalteparin’s Influence on REnally Compromised anti-Ten-A) Study | 18779469 | Douketis J, Cook D, Meade M, Guyatt G, Geerts W, Skrobik Y, Albert M, Granton J, Hebert PC, Pagliarello G, Marshall JC, Fowler R, Freitag A, Rabbat C, Anderson D, Zytaruk N, Heels-Ansdell D, Crowther MA for the Canadian Critical Care Trials Group. Renal Insufficiency with the Low-molecular-weight Heparin Dalteparin: An Assessment of Safety and Pharmacodynamics. The DIRECT (Dalteparin’s Influence on REnally Compromised anti-Ten-A) Study. Arch Intern Med 2008;168(16):1805-1812. PMID: 18779469 |
| Mehta S | Crit Care Med | 2008 | A randomized trial of daily awakening in critically ill patients managed with a sedation protocol – A pilot study | 18552687 | Mehta S, Burry L, Martinez-Motta C, Stewart TE, Hallett D, McDonald E, Clarke F, MacDonald R, Granton J, Matte A, Wong C, Suri A, Cook D for the Canadian Critical Care Trials Group. A randomized trial of daily awakening in critically ill patients managed with a sedation protocol – A pilot study. Crit Care Med 2008;36(7):2092-2099. PMID: 18552687 |
| Cook DJ | Crit Care Med | 2008 | Enrolment of ICU Patients into Clinical Studies: A Tri-national Survey | 18552686 | Cook DJ, Blythe D, Rischbieth A, Hebert PC, Zytaruk N, Menon K, Erikson S, Fowler R, Heels-Ansdell D, Meade MO for the Canadian Critical Care Trials Group. Enrolment of ICU Patients into Clinical Studies: A Tri-national Survey. Crit Care Med 2008; 36(7):2100-2105. PMID: 18552686 |
| Hutchison SJ | N Engl J Med | 2008 | Hypothermia Therapy Following Traumatic Brain Injury in Children | 18525042 | Hutchison SJ, Ward RE, Lacroix J, Hébert PC, Barnes MA, Bohn DJ, Dirks PB, Doucette S, Ferguson D, Gottesman R, Joffe AR, Kirpalani HM, Meyer PG, Morris KP, Moher D, Singh RN, Skippen PW, for the Hypothermia Pediatric Head Injury Trial investigators and for the Canadian Critical Care Trials Group. Hypothermia Therapy Following Traumatic Brain Injury in Children. N Engl J Med. 2008 Jun 5;358(23):2447-56. PMID: 18525042 |
| Cheung CZ | Intensive Care Medicine | 2008 | Recognition and labeling of delirium symptoms by intensivists: Does it matter? | 18087692 | Cheung CZ, Alibhai SMH, Robinson M, Tomlinson G, Chittock D, Drover J, Skrobik Y for the Canadian Critical Care Trials Group. Recognition and labeling of delirium symptoms by intensivists: Does it matter? Intensive Care Medicine 2008;34:437-446. PMID: 18087692 |
| Heyland DK | Crit Care Med | 2008 | A Randomized Trial of Combination Versus Monotherapy for the Empiric Treatment of Suspected Ventilator-Associated Pneumonia | 18091545 | Heyland DK, Dodek P, Muscedere J, Day A, Cook DJ for the Canadian Critical Care Trials Group. A Randomized Trial of Combination Versus Monotherapy for the Empiric Treatment of Suspected Ventilator-Associated Pneumonia. Crit Care Med 2008; 36: 737-744. PMID: 18091545 |
| Muscedere J | J Crit Care | 2008 | Comprehensive Evidence-Based Clinical Practice Guidelines for Ventilator-Associated Pneumonia: Diagnosis and Treatment | 18359431 | Muscedere J, Dodek PE, Keenan S, Fowler R, Cook DJ, Heyland DK for the VAP Guidelines Committee and for the Canadian Critical Care Trials Group.Comprehensive Evidence-Based Clinical Practice Guidelines for Ventilator-Associated Pneumonia: Diagnosis and Treatment. J Crit Care 2008; 23: 138-147. PMID: 18359431 |
| Muscedere J | J Crit Care | 2008 | Comprehensive Evidence-Based Clinical Practice Guidelines for Ventilator-Associated Pneumonia: Prevention | 18359430 | Muscedere J, Dodek PE, Keenan S, Fowler R, Cook DJ, Heyland D for the VAP Guidelines Committee and for the Canadian Critical Care Trials Group. Comprehensive Evidence-Based Clinical Practice Guidelines for Ventilator-Associated Pneumonia: Prevention. J Crit Care 2008; 23: 126-137. PMID: 18359430 |
| Sinuff T | J Crit Care | 2008 | Ventilator-associated pneumonia: Improving outcomes through guideline implementation | 18359429 | Sinuff T, Muscedere J, Cook D, Dodek P, Heyland D for the Canadian Critical Care Trials Group. Ventilator-associated pneumonia: Improving outcomes through guideline implementation. J Crit Care 2008; 23: 118-125. PMID: 18359429 |
| Joffe AR | J Crit Care | 2008 | The safety of targeted antibiotic therapy for ventilator-associated pneumonia: A multicenter observational study | 18359425 | Joffe AR, Muscedere J, Marshall JC, Su Y, Heyland DK for the Canadian Critical Care Trials Group. The safety of targeted antibiotic therapy for ventilator-associated pneumonia: A multicenter observational study. J Crit Care 2008; 23: 82-90. PMID: 18359425 |
| Albert M | J Crit Care | 2008 | Utility of gram stain in the clinical management of suspected ventilator-associated pneumonia: Secondary analysis of a multicenter randomized trial | 18359424 | Albert M, Friedrich JO, Adhikari NKJ, Day AG, Verdant C, Heyland DK for the Canadian Critical Care Trials Group. Utility of gram stain in the clinical management of suspected ventilator-associated pneumonia: Secondary analysis of a multicenter randomized trial. J Crit Care 2008; 23: 74-81. PMID: 18359424 |
| Shorr AF | J Crit Care | 2008 | Correlates of clinical failure in ventilator-associated pneumonia: Insights from a large, randomized trial | 18359423 | Shorr AF, Cook D, Jiang X, Muscedere J, Heyland D for the Canadian Critical Care Trials Group. Correlates of clinical failure in ventilator-associated pneumonia: Insights from a large, randomized trial. J Crit Care 2008; 23: 64-73. PMID: 18359423 |
| Sanders KM | J Crit Care | 2008 | Previous cultures are not clinically useful for guiding empiric antibiotics in suspected ventilator-associated pneumonia: Secondary analysis from a randomized trial | 18359422 | Sanders KM, Adhikari N, Friedrich JO, Day A, Jiang S, Heyland D for the Canadian Critical Care Trials Group. Previous cultures are not clinically useful for guiding empiric antibiotics in suspected ventilator-associated pneumonia: Secondary analysis from a randomized trial. J Crit Care 2008; 23: 58-63. PMID: 18359422 |
| Lauzier F | J Crit Care | 2008 | The value of pretest probability and modified clinical pulmonary infection score to diagnose ventilator-associated pneumonia | 18359421 | Lauzier F, Ruest A, Cook D, Dodek P, Albert M, Shorr AF, Day A, Jiang X, Heyland D for the Canadian Critical Care Trials Group. The value of pretest probability and modified clinical pulmonary infection score to diagnose ventilator-associated pneumonia. J Crit Care 2008; 23: 50-57. PMID: 18359421 |
| Muscedere JG | J Crit Care | 2008 | Determinants of outcome in patients with a clinical suspicion of ventilator-associated pneumonia | 18359420 | Muscedere JG, McColl C, Shorr A, Jiang X, Marshall J, Heyland DK for the Canadian Critical Care Trials Group. Determinants of outcome in patients with a clinical suspicion of ventilator-associated pneumonia. J Crit Care 2008; 23: 41-49. PMID: 18359420 |
| Parker CM | J Crit Care | 2008 | Ventilator-associated pneumonia caused by multidrug-resistant organisms or Pseudomonas aeruginosa: Prevalence, incidence, risk factors, and outcomes | 18359417 | Parker CM, Kutsogiannis J, Muscedere J, Cook D, Dodek P, Day AG, Heyland DK for the Canadian Critical Care Trials Group. Ventilator-associated pneumonia caused by multidrug-resistant organisms or Pseudomonas aeruginosa: Prevalence, incidence, risk factors, and outcomes. J Crit Care 2008;23: 18-26. PMID: 18359417 |
| Delisle MS | J Crit Care | 2008 | The clinical significance of Candida colonization of respiratory tract secretions in critically ill patients | 18359416 | Delisle MS, Williamson DR, Perreault MM, Albert M, Jiang X, Heyland DK. The clinical significance of Candida colonization of respiratory tract secretions in critically ill patients. J Crit Care 2008; 23: 11-17. PMID: 18359416 |
| Muscedere JG | J Crit Care | 2008 | The impact of ventilator-associated pneumonia on the Canadian health care system | 18359415 | Muscedere JG, Martin CM, Heyland DK. The impact of ventilator-associated pneumonia on the Canadian health care system. J Crit Care 2008; 23: 5-10. PMID: 18359415 |
| Cook D | Crit Care Med | 2008 | Venous thromboembolism and bleeding in critically ill patients with severe renal insufficiency receiving dalteparin thromboprophylaxis: prevalence, incidence and risk factors. | 18315876 | Cook D, Douketis J, Meade M, Guyatt G, Zytaruk N, Granton J, Skrobik Y, Albert M, Fowler R, Hebert P, Pagliarello G, Friedrich J, Freitag A, Karachi T, Rabbat C, Heels-Ansdell D, Geerts W, Crowther M; Canadian Critical Care Trials Group.Venous thromboembolism and bleeding in critically ill patients with severe renal insufficiency receiving dalteparin thromboprophylaxis: prevalence, incidence and risk factors.Crit Care. 2008;12(2):R32. PMID: 18315876 |
| Beaudin S | Journal of Immunology | 2008 | Activated protein C up-regulates IL-10 and inhibits tissue factor in bloodmonocytes | | Toltl LJ, Beaudin S, Liaw PC; Canadian Critical Care Translational Biology Group. Activated protein C up-regulates IL-10 and inhibits tissue factor in bloodmonocytes. J Immunol. 2008 Aug 1;181(3):2165-73. |
| McIntyre LL | Can J Anaesth | 2007 | Resuscitating patients with early severe sepsis: A Canadian multicenter observational study | 17934160 | McIntyre LL, Fergusson D, Cook DJ, Nair RC, Bell D, Dhingra V, Hutton B, Magder S, Hébert PC for the Canadian Critical Care Trials Group. Resuscitating patients with early severe sepsis: A Canadian multicenter observational study. Can J Anaesth. 2007 Oct;54(10):790-8. PMID: 17934160 |
| McIntyre LA | Crit Care | 2007 | A Survey of Canadian Intensivists Resuscitation Practices in Early Septic Shock | 17623059 | McIntyre LA, Hebert PC, Fergusson D, Cook DJ, Aziz A for the Canadian Critical Care Trials Group. A Survey of Canadian Intensivists Resuscitation Practices in Early Septic Shock. Crit Care. 2007;11(4):R74. PMID: 17623059 |
| Lacroix J | N Engl J Med | 2007 | Transfusion Requirements In Pediatric Intensive Care Units: A Noninferiority Tria | 17442904 | Lacroix J, Hébert PC, Hutchison JS, Hume HA, Tucci M, Ducruet T, Gauvin F, Collet JP, Toledano BJ, Robillard P, Joffe A, Biarent D, Meert K, Peters MJ on behalf of the TRIPICU investigators, for the Canadian Critical Care Trials Group and the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. Transfusion Requirements In Pediatric Intensive Care Units: A Noninferiority Trial. N Engl J Med 2007;356(16):1609-1619. PMID: 17442904 |
| Hutchison JS | Journal of Neurotrauma | 2007 | Protein biomarkers in sera of paediatric patients with severe traumatic brain injury identified | | Arsalan S. Haqqani, James S. Hutchison, Roxanne Ward, Danica B. Stanimirovic for the Canadian Critical Care Translational Biology Group. Biomarkers and diagnosis; Protein biomarkers in sera of paediatric patients with severe traumatic brain injury identified by ICAT-LC-MS/MS. Journal of Neurotrauma, 2007, 24:54-74. |
| Menon K | Pediatr Crit Care Med. | 2007 | Identification of adrenal insufficiency in pediatric critical illness. | 17417118 | Menon K, Lawson M.Identification of adrenal insufficiency in pediatric critical illness. Pediatr Crit Care Med. 2007 May;8(3):276-8. PMID: 17417118 |
| Heyland DK | N Engl J Med | 2006 | A randomized trial of diagnostic techniques and empiric broad-spectrum antibiotics for suspected ventilator-associated pneumonia | 17182987 | Heyland DK, Cook D, Dodek P, Muscedere J, Day A. The Canadian Critical Care Trials Group. A randomized trial of diagnostic techniques and empiric broad-spectrum antibiotics for suspected ventilator-associated pneumonia. N Engl J Med 2006;355(25):2619-2630. PMID: 17182987 |
| Cook DJ | Am J Crit Care | 2006 | Levels of Care in the Intensive Care Unit: A Research Program | 16632769 | Cook DJ, Rocker G, Marshall J, Griffith L, McDonald E, Guyatt GH for the Level of Care Study Investigators and the Canadian Critical Care Trials Group. Levels of Care in the Intensive Care Unit: A Research Program. Am J Crit Care 2006 May;15(3):269-79. PMID: 16632769 |
| McIntyre L | J Neuro Critical Care | 2006 | Effect of a liberal versus restrictive transfusion strategies on mortality in patients with moderate to severe head injury? | 16960287 | McIntyre L, Fergusson D, Hutchinson J, Pagliarello G, Marshall J, Yetisir E, Hare GMT, Blajchman MJ, Hebert PC for The Canadian Care Trials Group. Effect of a liberal versus restrictive transfusion strategies on mortality in patients with moderate to severe head injury? J Neuro Critical Care 2006;5:4-9. PMID: 16960287 |
| Hutchison J | Developmental Neuroscience | 2006 | Hypothermia Pediatric Head Injury Trial (HyP-HIT): The value of a pre-trial clinical evaluation phase | 16943652 | Hutchison J, Ward R, Lacroix J, Hébert P, Skippen P, Barnes M, Meyer P, Morris K, Kirpalani H, Singh R, Dirks P, Bohn D, Moher D, for the HyP-HIT investigators and the Canadian Critical Care Trials Group. Hypothermia Pediatric Head Injury Trial (HyP-HIT): The value of a pre-trial clinical evaluation phase. Developmental Neuroscience 2006;28:291-301. PMID: 16943652 |
| Cheung AM | Am J Resp Crit Care Med | 2006 | Two-year health care utilization, costs and outcomes in survivors of the acute respiratory distress syndrome | 16763220 | Cheung AM, Tansey CM, Tomlinson G, Diaz-Granados N, Matte-Martyn A, Mehta S, Mazer D, Guest CB, Stewart TE, Al-Saidi F, Cooper AB, Cook DJ, Slutsky AS, Herridge MS for The Canadian Critical Care Trials Group. Two-year health care utilization, costs and outcomes in survivors of the acute respiratory distress syndrome. Am J Resp Crit Care Med 2006; 174:538-544. PMID: 16763220 |
| Heyland DK | Proc Nutr Soc | 2006 | REducing Deaths due to OXidative Stress: The REDOXS© Study: Rationale and study design for a randomized trial of glutamine and antioxidant supplementation in critically ill patients | 16923310 | Heyland DK, Dhaliwal R, Day A, Muscedere J, Drover J, Suchner U, Cook DJ, For the Canadian Critical Care Trials Group. REducing Deaths due to OXidative Stress: The REDOXS© Study: Rationale and study design for a randomized trial of glutamine and antioxidant supplementation in critically ill patients. Proc Nutr Soc 2006;65(3):250-263. PMID: 16923310 |
| Parshuram CS | Crit Care Med | 2006 | In-house, overnight physician staffing: A cross-sectional survey of Canadian adult and paediatric ICUs | 16625115 | Parshuram CS, Mehta G, Kirpalani H, Granton J, Cook DJ, for The Canadian Critical Care Trials Group. In-house, overnight physician staffing: A cross-sectional survey of Canadian adult and paediatric ICUs. Crit Care Med 2006;34(6):1674-1678. PMID: 16625115 |
| Mehta S | Crit Care Med | 2006 | A Canadian survey of the use of sedatives, analgesics, and neuromuscular blocking agents in critically ill patients | 16424717 | Mehta S, Burry L, Fischer S, Martinez-Motta JC, Hallett D, Bowman D, Wong C, Meade MO, Stewart TE, Cook DJ for The Canadian Critical Care Trials Group. A Canadian survey of the use of sedatives, analgesics, and neuromuscular blocking agents in critically ill patients. Crit Care Med 2006; 34:374-380. PMID: 16424717 |
| Tinmouth A | Transfusion | 2006 | Clinical consequences of red cell storage in the critically ill. | 17076859 | Tinmouth A, Fergusson D, Yee IC, Hébert PC; ABLE Investigators; Canadian Critical Care Trials Group. Clinical consequences of red cell storage in the critically ill. Transfusion. 2006;46(11):2014-27. PMID: 17076859 |
| Turgeon AF | Can J Anaesth. | 2006 | Red blood cell transfusion practices amongst Canadian anesthesiologists: a survey. | 16575031 | Turgeon AF, Fergusson DA, Doucette S, Khanna MP, Tinmouth A, Aziz A, Hébert PC. Red blood cell transfusion practices amongst Canadian anesthesiologists: a survey. Can J Anaesth. 2006;53(4):344-52. PMID: 16575031 |
| Hebert PC | Anesth Analg | 2005 | A pilot trial evaluating the clinical effects of prolonged storage of red cell | 15845701 | Hebert PC, Chin-Yee I, Fergusson D, Blajchman M, Martineau R, Clinch J, Olberg B for the Canadian Critical Care Trials Group. A pilot trial evaluating the clinical effects of prolonged storage of red cell. Anesth Analg 2005 May;100(5):1433-8. PMID: 15845701 |
| Patel R | J Crit Care | 2005 | Burden of illness: Thrombo-embolism in critical care (BITEC) study | 16310605 | Patel R, Cook DJ, Meade MO, Griffith L, Mehta S, Rocker G, Marshall J, Hodder R, Martin C, Heyland D, Peters S, Muscadere J, Soth M, Campbell N, Guyatt GH, for The Canadian Critical Care Trials Group. Burden of illness: Thrombo-embolism in critical care (BITEC) study. J Crit Care 2005;20:341-347. PMID: 16310605 |
| Cook DJ | J Crit Care | 2005 | Prophylaxis of ThromboEmbolism in Critical Care Trial: (PROTECT): A Pilot Study | 16310609 | Cook DJ, Rocker G, Meade MO, Guyatt GH, Geerts W, Anderson D, Skrobik Y, Hébert P, Albert M, Cooper DJ, Bates S, Caco C, Finfer S, Freitag A, Granton J, Jones G, Langevin S, Mehta G, Pagliarello G, Poirier G, Rabbat C, Schiff D, Griffith LE, Crowther MA, for the PROTECT Investigators and the Canadian Critical Care Trials Group. Prophylaxis of ThromboEmbolism in Critical Care Trial: (PROTECT): A Pilot Study. J Crit Care 2005;20:364-372. PMID: 16310609 |
| Kotsakis A | J Crit Care | 2005 | Clinically Important Venous Thromboembolism in Pediatric Critical Care: A Canadian Survey | 16310610 | Kotsakis A, Cook DJ, Griffith LE, Anton N, Massicotte P, MacFarland K, Farrell R, Hutchison J, for the Canadian Critical Care Trials Group. Clinically Important Venous Thromboembolism in Pediatric Critical Care: A Canadian Survey. J Crit Care 2005;20:373-380. PMID: 16310610 |
| Liet JM | J Pediatrics | 2005 | Non-invasive therapy with helium-oxygen for severe RSV bronchiolitis: A multicenter randomized controlled trial | 16356437 | Liet JM, Millotte B, Tucci M, LaFlamme S, Hutchison J, Creery D, Ducruet T, Lacroix J, for The Canadian Critical Care Trials Group. Non-invasive therapy with helium-oxygen for severe RSV bronchiolitis: A multicenter randomized controlled trial. J Pediatrics 2005;147:812-817. PMID: 16356437 |
| Hutton B | Can J Anaesth. | 2005 | Transfusion rates vary significantly amongst Canadian medical centres. | 15983142 | Hutton B, Fergusson D, Tinmouth A, McIntyre L, Kmetic A, Hébert PC. Transfusion rates vary significantly amongst Canadian medical centres. Can J Anaesth. 2005;52(6):581-90. PMID: 15983142 |
| Tinmouth A | Arch Intern Med. | 2005 | Reducing the amount of blood transfused: a systematic review of behavioral interventions to change physicians' transfusion practices. | 15851633 | Tinmouth A, Macdougall L, Fergusson D, Amin M, Graham ID, Hebert PC, Wilson K. Reducing the amount of blood transfused: a systematic review of behavioral interventions to change physicians' transfusion practices. Arch Intern Med. 2005;165(8):845-52. PMID: 15851633 |
| Hébert PC | Crit Care Med. | 2005 | Revisiting transfusion practices in critically ill patients. | 15644642 | Hébert PC, Fergusson DA, Stather D, McIntyre L, Martin C, Doucette S, Blajchman M, Graham ID; Canadian Critical Care Trials Group. Revisiting transfusion practices in critically ill patients. Crit Care Med. 2005;33(1):7-12. PMID: 15644642 |
| Cook DJ | Crit Care | 2004 | Clinically important deep vein thrombosis in the ICU: A survey of intensivists | 15153243 | Cook DJ, Meade MO, Guyatt GH, Griffith LE, Granton J, Geerts W, Crowther M for the Canadian Critical Care Trials Group. Clinically important deep vein thrombosis in the ICU: A survey of intensivists. Crit Care 2004;8:R145-R152. PMID: 15153243 |
| Sinuff T | Can J Anesth | 2004 | Resuscitation directives in the intensive care unit | 15574557 | Sinuff T, Cook DJ, Rocker GM, Griffith L, Walter SD, Fisher M, Dodek P, Sjokvist P, McDonald E, Marshall J, Levy M, Guyatt G, and The Canadian Critical Care Trials Group. Resuscitation directives in the intensive care unit. Can J Anesth 2004;51(10):1034-1041. PMID: 15574557 |
| McIntyre L | J. Trauma | 2004 | Is a restrictive transfusion strategy safe in resuscitated and critically ill trauma victims? | 15454803 | McIntyre L, Hébert PC, Wells G, Fergusson D, Marshall J, Yetisir E, Blajchman MJ, for The Canadian Critical Care Trials Group. Is a restrictive transfusion strategy safe in resuscitated and critically ill trauma victims? J. Trauma 2004;57(3):563-568. PMID: 15454803 |
| Griffith L | Intensive Care Med | 2004 | Predictors of clinician discomfort with daily life support plans for mechanically ventilated patients | 15221128 | Griffith L, Cook D, Hanna S, Rocker G, Sjokvist P, Dodek P, Marshall JC, Levy M, Varon J, Finfer S, Jaeschke R, Buckingham L, Guyatt G for The Canadian Critical Care Trials Group. Predictors of clinician discomfort with daily life support plans for mechanically ventilated patients. Intensive Care Med 2004;30:1783-1790. PMID: 15221128 |
| Rocker G | Crit Care Med | 2004 | Clinician predictions of mortality in the intensive care unit | 15190965 | Rocker G, Cook D, Sjokvist P, Weaver B, Finfer S, McDonald E, Marshall J, Kirby A, Levy M, Dodek P, Heyland D, Guyatt G, for the Canadian Critical Care Trials Group. Clinician predictions of mortality in the intensive care unit. Crit Care Med 2004;32(5):1149-1154. PMID: 15190965 |
| Dodek PM | Ann Intern Med | 2004 | Evidence based clinical practice guideline for the prevention of ventilator-associated pneumonia | 15313747 | Dodek PM, Cook DJ, Keenan S, Heyland DK, Brun-Buisson C, Hall R, Jacka M, Foster D, Hand L, Mehta N, Muscedere J, for The Canadian Critical Care Trials Group. Evidence based clinical practice guideline for the prevention of ventilator-associated pneumonia. Ann Intern Med. 2004 Aug 17;141(4):305-13. PMID: 15313747 |
| Meade MO | Crit Care Med | 2004 | Survey of interventions for the prevention and treatment of acute respiratory distress syndrome | 15071383 | Meade MO, Jacka MJ, Cook DJ, Dodek P, Griffith L, Guyatt GH, for The Canadian Critical Care Trials Group. Survey of interventions for the prevention and treatment of acute respiratory distress syndrome. Crit Care Med 2004;32(4):946-954. PMID: 15071383 |
| Hébert PC | Crit Care Clin. | 2004 | Clinical consequences of anemia and red cell transfusion in the critically ill. | 15135462 | Hébert PC, McDonald BJ, Tinmouth A.Clinical consequences of anemia and red cell transfusion in the critically ill. Crit Care Clin. 2004;20(2):225-35. PMID: 15135462 |
| Guyatt G | J Crit Care | 2003 | The influence of perceived functional and employment status on cardiopulmonary resuscitation directives. | 14595566 | Guyatt G, Cook D, Weaver B, Rocker G, Dodek P, Sjokvist P, Hamielec C, Puksa S, Marshall J, Foster D, Levy M, Varon J, Thorpe K, Fisher M, Walter S for the Level of Care Investigators and The Canadian Critical Care Trials Group. The influence of perceived functional and employment status on cardiopulmonary resuscitation directives. J Crit Care 2003;18(3):133-141. PMID: 14595566 |
| Herridge MS | N Engl J Med | 2003 | One year outcomes in survivors of the acute respiratory distress syndrome | 12594312 | Herridge MS, Cheung AM, Tansey CM, Matte-Martyn A, Diaz-Granados N, Al-Saidi F, Cooper A, Guest C, Mazer D, Mehta S, Stewart T, Barr A, Cook DJ, Slutsky A, for The Canadian Critical Care Trials Group. One year outcomes in survivors of the acute respiratory distress syndrome. N Engl J Med. 2003 Feb 20;348(8):683-93. PMID: 12594312 |
| Sandham JD | N Engl J Med | 2003 | A randomised controlled trial of the use of pulmonary-artery catheters in high-risk surgical patients | 12510037 | Sandham JD, Hull RD, Brant RF, Knox L, Pineo GF, Doig CJ, Laporta DP, Viner S, Passerini L, Devitt H, Kirby A, Jacka M, for The Canadian Critical Care Trials Group. A randomised controlled trial of the use of pulmonary-artery catheters in high-risk surgical patients. N Engl J Med. 2003 Jan 2;348(1):5-14. PMID: 12510037 |
| Cook DJ | N Engl J Med | 2003 | Withdrawal of mechanical ventilation in anticipation of death in the intensive care unit | 13679526 | Cook DJ, Rocker G, Marshall J, Sjokvist P, Dodek P, Griffith L, Freitag A, Varon J, Bradley C, Levy M, Finfer S, Walter, S Guyatt GH, for the Level of Care Study Investigators and The Canadian Critical Care Trials Group. Withdrawal of mechanical ventilation in anticipation of death in the intensive care unit. N Engl J Med 2003;349:1123-1132. PMID: 13679526 |
| Laverdiere C | Pediatr Crit Care Med | 2002 | Survey on transfusion practices of pediatric intensivists | 12780950 | Laverdiere C, Gauvin F, Hébert PC, Infante-Rivard C, Hume H, Toledano BJ, Guertin M-C, Lacroix J, for The Canadian Critical Care Trials Group. Survey on transfusion practices of pediatric intensivists. Pediatr Crit Care Med. 2002 Oct;3(4):335-40. PMID: 12780950 |
| Heyland DK | J Crit Care | 2002 | Prevention of ventilator-associated pneumonia: current practice in Canadian intensive care units. | 12297991 | Heyland DK, Cook DJ, Dodek PM.Prevention of ventilator-associated pneumonia: current practice in Canadian intensive care units.J Crit Care. 2002 Sep;17(3):161-7. PMID: 12297991 |
| Menon K | Pediatr Crit Care Med. | 2002 | Adrenal function in pediatric critical illness | 12780978 | Menon K, Clarson C. Adrenal function in pediatric critical illness.Pediatr Crit Care Med. 2002 Apr;3(2):112-116. PMID: 12780978
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| Cook DJ | Lancet | 2001 | Cardiopulmonary resuscitation directives on admission to the Intensive Care Unit: an international observational study | 11747918 | Cook DJ, Guyatt GH, Rocker G, Sjokvist P, Weaver B, Dodek P, Marshall J, Leasa D, Levy M, Varon J, Fisher M, Cook DJ, for The Canadian Critical Care Trials Group. Cardiopulmonary resuscitation directives on admission to the Intensive Care Unit: an international observational study. Lancet 2001;358:1941-1945. PMID: 11747918 |
| Cook R | Crit Care Med | 2001 | Multiple organ dysfunction: Baseline and serial component scores | 11700393 | Cook R, Cook DJ, Tilley J, Lee KA, Marshall J, for The Canadian Critical Care Trials Group. Multiple organ dysfunction: Baseline and serial component scores. Crit Care Med 2001;29(11):2046-2050. PMID: 11700393 |
| Hébert PC | Chest | 2001 | Do blood transfusions improve outcomes from mechanical ventilation? | 11399714 | Hébert PC, Blajchman MA, Cook DJ, Yetisir E, Wells G, Marshall J, Schweitzer I, and the Transfusion Requirements in Critical Care Investigators for The Canadian Critical Care Trials Group. Do blood transfusions improve outcomes from mechanical ventilation? Chest 2001;119(6):1850-1857. PMID: 11399714 |
| Cook DJ | ntensive Care Med | 2001 | On the need for observational studies to design and interpret randomized trials in ICU patients: a case study in stress ulcer prophylaxis | 11396278 | Cook DJ, Heyland D, Marshall J, for The Canadian Critical Care Trials Group. On the need for observational studies to design and interpret randomized trials in ICU patients: a case study in stress ulcer prophylaxis. Intensive Care Med. 2001 Feb;27(2):347-54. PMID: 11396278 |
| Hébert PC | Crit Care Med | 2001 | Is a low transfusion threshold safe in critically ill patients with cardiovascular diseases? | 11246298 | Hébert PC, Yetisir E, Martin C, Blajchman MA, Wells G, Marshall J, Tweeddale M, Pagliarello G, Schweitzer I, and the Transfusion Requirements in Critical Care Investigators for The Canadian Critical Care Trials Group. Is a low transfusion threshold safe in critically ill patients with cardiovascular diseases? Crit Care Med 2001;29(2):227-234. PMID: 11246298 |
| Cook DJ | Crit Care | 2001 | The attributable mortality and length of intensive care unit stay of clinically important gastrointestinal bleeding in critically ill patients. | 11737927 | Cook DJ, Griffith LE, Walter SD, Guyatt GH, Meade MO, Heyland DK, Kirby A, Tryba M; Canadian Critical Care Trials Group.The attributable mortality and length of intensive care unit stay of clinically important gastrointestinal bleeding in critically ill patients. Crit Care. 2001;5(6):368-75. PMID: 11737927 |
| Foster D | Crit Care Med | 2000 | Use of a screen log to audit patient recruitment into multiple randomized trials in the ICU | 10752843 | Foster D, Cook DJ, Granton J, Steinberg M, Marshall J. for The Canadian Critical Care Trials Group. Use of a screen log to audit patient recruitment into multiple randomized trials in the ICU. Crit Care Med 2000;28(3):867-871. PMID: 10752843 |
| Cook DJ | Crit Care Med | 1999 | Risk factors for clinically important upper gastrointestinal bleeding in patients requiring mechanical ventilation | 10628631 | Cook DJ, Heyland D, Griffith LE, Cook RJ, Marshall JC, Pagliarello G, for The Canadian Critical Care Trials Group. Risk factors for clinically important upper gastrointestinal bleeding in patients requiring mechanical ventilation. Crit Care Med 1999;27(12):2812-2817. PMID: 10628631 |
| Cook DJ | CMAJ | 1999 | Life support in the intensive care unit: a qualitative investigation of technological purposes | 10569086 | Cook DJ, Giacomini M, Johnson N, Willms D, for The Canadian Critical Care Trials Group. Life support in the intensive care unit: a qualitative investigation of technological purposes. CMAJ 1999 Nov 2;161(9):1109-13. PMID: 10569086 |
| Heyland DK | Crit Care Med | 1999 | The effect of acidified enteral feeds on gastric colonization in critically ill patients: Results of a multicenter randomized trial | 10579255 | Heyland DK, Cook DJ, Schoenfeld PS, Freitag A, Varon J, Wood G, for The Canadian Critical Care Trials Group. The effect of acidified enteral feeds on gastric colonization in critically ill patients: Results of a multicenter randomized trial. Crit Care Med 1999;27(11):2399-1406. PMID: 10579255 |
| Hébert PC | Crit Care Med | 1999 | Variation in red cell transfusion practice in the intensive care unit | 11056725 | Hébert PC, Wells G, Martin C, Tweeddale M, Marshall J, Blajchman M, Pagliarello G, Sandham D, Schweitzer I, Boisvert D, Calder L, for the Transfusion Requirements in Critical Care (TRICC) Investigators and The Canadian Critical Care Trials Group. Variation in red cell transfusion practice in the intensive care unit. Crit Care 1999;3(2):57-63. PMID: 11056725 |
| Heyland DK | Chest | 1999 | The clinical utility of invasive diagnostic techniques in the setting of ventilator-associated pneumonia | 10208211 | Heyland DK, Cook DJ, Marshall J, Heule M, Guslits B, Lang J, Jaeschke R, for The Canadian Critical Care Trials Group. The clinical utility of invasive diagnostic techniques in the setting of ventilator-associated pneumonia. Chest 1999;115(4):1076-1084. PMID: 10208211 |
| Heyland DK | Am J Respir Crit Care Med | 1999 | The attributable morbidity and mortality of ventilator-associated pneumonia | 10194173 | Heyland DK, Cook DJ, Griffith LE, Keenan SP, Brun-Buisson C, for The Canadian Critical Care Trials Group. The attributable morbidity and mortality of ventilator-associated pneumonia. Am J Respir Crit Care Med 1999;159(4):1249-1256. PMID: 10194173 |
| Hébert PC | N Engl J Med | 1999 | Transfusion requirements in critical care: a multicenter randomized controlled clinical trial | 9971864 | Hébert PC, Wells G, Blajchman MA, Marshall J, Martin C, Pagliarello G, Tweeddale M, Schweitzer I, Yetisier E and the Transfusion Requirements in Critical Care Investigators, for The Canadian Critical Care Trials Group. Transfusion requirements in critical care: a multicenter randomized controlled clinical trial. N Engl J Med 1999;340(6):409-417. PMID: 9971864 |
| Hébert PC | Br J Anaesth | 1998 | Transfusion requirements in critical care: a multicentre randomized controlled clinical study | 10318985 | Hébert PC for the Transfusion Requirements in Critical Care Investigators and The Canadian Critical Care Trials Group. Transfusion requirements in critical care: a multicentre randomized controlled clinical study. Br J Anaesth 1998 Dec;81 Suppl 1:25-33. PMID: 10318985 |
| Cook DJ | J Crit Care | 1998 | Lessons from adjudicating pneumonia in a randomized trial of critically ill patients | 9869541 | Cook DJ, Walter SD, Freitag A, Guyatt GH, Devitt H, Meade MO, Griffith LE, Sarabia A, Fuller, H, Turner M, Gough K, for The Canadian Critical Care Trials Group. Lessons from adjudicating pneumonia in a randomized trial of critically ill patients. J Crit Care 1998;13(4):159-163. PMID: 9869541 |
| Cook DJ | Ann Intern Med | 1998 | Incidence of and risk factors for ventilator-associated pneumonia in critically ill patients | 9735080 | Cook DJ, Walter S, Cook RJ, Griffith LE, Guyatt GH, Leasa D, Jaeschke R, Brun-Buisson C, for The Canadian Critical Care Trials Group. Incidence of and risk factors for ventilator-associated pneumonia in critically ill patients. Ann Intern Med 1998 Sep 15;129(6):433-40. PMID: 9735080 |
| Cook DJ | N Engl J Med | 1998 | A comparison of sucralfate and ranitidine for prevention of upper gastrointestinal bleeding in patients requiring mechanical ventilation | 9504939 | Cook DJ, Guyatt GH, Marshall J, Leasa D, Fuller H, Hall R, Peters S, Rutledge F, Griffith L, McLellan PA, Wood G, Kirby A, Tweeddale M, Pagliarello J, Johnston R, for The Canadian Critical Care Trials Group. A comparison of sucralfate and ranitidine for prevention of upper gastrointestinal bleeding in patients requiring mechanical ventilation. N Engl J Med 1998;338(12):791-797. PMID: 9504939 |
| Hébert PC | Crit Care Med | 1998 | A Canadian survey of transfusion practices in critically ill patients | 9504576 | Hébert PC, Wells G, Martin C, Tweeddale M, Marshall J, Blajchman M, Pagliarello G, Schweitzer I, Calder L, for the Transfusion Requirements in Critical Care Investigators and The Canadian Critical Care Trials Group. A Canadian survey of transfusion practices in critically ill patients. Crit Care Med 1998;26(3):482-487. PMID: 9504576 |
| Walter S | Crit Care Med | 1998 | Confidence and decision making in the withdrawal of life support from the critically ill | 9428542 | Walter S, Cook DJ, Guyatt GH, Spanier A, Jaeschke R, Todd T, Streiner DL, for The Canadian Critical Care Trials Group. Confidence and decision making in the withdrawal of life support from the critically ill. Crit Care Med 1998;26(1):44-49. PMID: 9428542 |
| Hébert PC | Am J Respir Crit Care Med | 1997 | Does transfusion practice affect mortality in critically ill patients? | 9154866 | Hébert PC, Wells G, Tweeddale M, Martin C, Marshall JC, Pham B, Blajchman M, Schweitzer I, Pagliarello G for the Canadian Critical Care Trials Group. Does transfusion practice affect mortality in critically ill patients? Am J Respir Crit Care Med. 1997 May;155(5):1618-23. PMID: 9154866 |
| Cook DJ | Intensive Care World | 1997 | The Canadian Critical Care Trials Group: A collaborative, educational organization for the advancement of adult ICU research | No PMID found | Cook DJ, Todd TRJ. The Canadian Critical Care Trials Group: A collaborative, educational organization for the advancement of adult ICU research. Intensive Care World 1997;14(2):68-70. No PMID found. |
| Heyland DK | Clin Intens Care | 1996 | The clinical and economic consequence of clinically important gastrointestinal bleeding in critically ill patients | No PMID found | Heyland DK, Gafni A, Griffith L, Cook DJ, Marshall JC, Fuller HD, Todd TRJ, Guslits B, Heule M, Hewson JR, Lacroix J, Noseworthy T, Powles ACP, for The Canadian Critical Care Trials Group. The clinical and economic consequence of clinically important gastrointestinal bleeding in critically ill patients. Clin Intens Care 1996;7(3):121-125. No PMID found |
| Cook DJ | JAMA | 1995 | Determinants in Canadian health care workers of the decision to withdraw life support from the critically ill | 7853627 | Cook DJ, Guyatt GH, Jaeschke R, Reeve J, Spanier A, King D, Molloy DW, Willan A, Streiner D, for The Canadian Critical Care Trials Group. Determinants in Canadian health care workers of the decision to withdraw life support from the critically ill. JAMA 1995;273(9):703-708. PMID: 7853627 |
| Hébert PC | JAMA | 1995 | ransfusion requirements in critical care: A pilot study | 7723158 | Hébert PC, Wells G, Marshall JC, Martin C, Tweeddale M, Pagliarello G, Blajchman M, for The Canadian Critical Care Trials Group. Transfusion requirements in critical care: A pilot study. JAMA 1995;273:1439-1444. PMID: 7723158 |
| Cook DJ | N Engl J Med | 1994 | Risk factors for gastrointestinal bleeding in critically ill patients | 8284001 | Cook DJ, Fuller H, Guyatt GH, Marshall JC, Leasa D, Hall R, Winton TL, Rutledge F, Todd TRJ, Roy P, Lacroix J, Griffith LE, Willan A, for The Canadian Critical Care Trials Group. Risk factors for gastrointestinal bleeding in critically ill patients. N Engl J Med 1994;330:377-381. PMID: 8284001 |