CCCTG Logo  

Contact | How to Join 

  
       
  HOME
  ABOUT US
  NEWS & EVENTS
  PUBLICATIONS
  » Peer Reviewed
  » Submitted Manuscripts
  » Affiliated Publications
  » Abstracts
   
  GRANTS
  LINKS
  MEMBER LOGIN
 
what's new  
The CCCTG 2010 Spring Meeting will be held on June 14 - 17, 2010 at the Rodd Brudenell River Resort, Charlottetown, PEI More »  
   
 
focus on  

 
   
CCCTG Executive Board
 
 

Publications

Peer Reviewed Publications

  1. Keenan SP, Sinuff T, Burns K, Muscedere J, Kutsogiannis J, Sangeeta M, Dodek P, Cook DJ, Ayas N, Adhikari N, Hand L, Scales D, Pagnotta R, Lazosky L, Rocker G, Dial S, Laupland K, Sanders K for the Canadian Critical Care Trials Group and Canadian Critical Care Society. Noninvasive Ventilation Guidelines Group. Clinical practice guidelines for noninvasive positive pressure ventilation (NPPV) and noninvasive continuous positive airway pressure (nCPAP) in the acute care setting. Can Med Assoc J 2010 (in press)
  2. Gauvin F, Spinella PC, Lacroix J, Choker G, Ducruet T, Karam O, Hébert PC, Hutchison JS, Hume HA, Tucci M, on behalf of the Canadian Critical Care Trials Group and the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.  Association between length of storage of transfused red blood cells and multiple organ dysfunction syndrome in pediatric intensive care patients. Transfusion 2010 (in press).
  3. Rouette J, Trottier H, Ducruet T, Beaunoyer M, Lacroix J, Tucci M for the CCCTG and PALISI.  Red blood cell transfusion threshold in post-surgical pediatric intensive care patients: a randomized clinical trial.  Annals of Surgery 2010; 251:421-7.
  4. Willems A, Harrington K, Lacroix J, Biarent D, Joffe ARI, Wensley D, Ducruet T, Hébert PC, Tucci M, on behalf of the TRIPICU investigators, for the Canadian Critical Care Trials Group and the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.  Comparison of two red-cell transfusion strategies after pediatric cardiac surgery: a subgroup analysis.  Crit Care Med 2010;38(2):649-56.
  5. Freed DH, Henzler D, White CW, Fowler R, Zarychanski R, Hutchison J, Arora RC, Manji RA, Legare JF, Drews T, Veroukis S, Kesselman M, Guerguerian AM, Kumar A; for the Canadian Critical Care Trials Group. Extracorporeal lung support for patients who had severe respiratory failure secondary to influenza A (H1N1) 2009 infection in Canada. Can J Anaesth 2010;57(3):240-7.
  6. Jouvet P, Hutchison J, Pinto R, Menon K, Rodin R, Choong K, Kesselman M, Veroukis S, André Dugas M, Santschi M, Guerguerian AM, Withington D, Alsaati B, Joffe AR, Drews T, Skippen P, Rolland E, Kumar A, Fowler RA, for the Canadian Critical Care Trials Group H1N1 Collaborative. Critical illness in children with influenza A/pH1N1 2009 infection in Canada. Pediatr Crit Care Med 2010 Mar 19. [Epub ahead of print].
  7. Menon K, Ward RE, Lawson ML, Gaboury I, Hutchison JS, Hébert PC, and Canadian Critical Care Trials Group.  A Prospective Multi-Center Study of Adrenal Function in Critically Ill Children.  Am J Respir Crit Care Med 2010; published ahead of print on March 18, 2010
  8. Crowther MA, Cook DJ, Albert M, Williamson D, Meade M, Granton J, Skrobik Y, Langevin S, Mehta S, Hebert PC, Guyatt GH, Geerts W, Rabbat C. Douketis J, Zytaruk N, Sheppard J, Greinacher A, Warkentin TE for the Canadian Critical Care Trials Group.   The 4Ts Scoring System for Heparin Induced Thrombocytopenia In Medical-Surgical ICU Patients. J Crit Care 2010 (in press).
  9. Choong K, Bohn D, Fraser DD, Gaboury I, Hutchison JS, Joffe AR, Litalien C, Menon K, McNamara P, Ward RB with the Canadian Critical Care Trials Group.  Vasopressin in Pediatric Vasodilatory Shock - A Multi-center Randomized Controlled Trial.  Am J Respir Crit Care Med 2009;180(7)632-9.
  10. Burns KE, Meade MO, Lessard M, Keenan SP, Lelouche F.  Wean Earlier and Automatically with New Technology: The WEAN Study: a protocol of a multicenter randomized controlled trial.  Trials 2009;10:81.
  11. Kumar A, Zarychanski R, Pinto R, Cook DJ, Marshall J, Lacroix J, Stelfox T, Bagshaw S, Choong K, Lamontagne F, Turgeon A, Lapinsky S, Ahern SP, Smith O, Siddiqui F, Jouvet J, Khwaja K, McIntyre L, Menon K, Hutchison J, Hornstein D, Joffe A, Lauzier F, Singh J, Karachi T, Wiebe K, Olafson K, Ramsey C, Sharma S, Dodek P, Meade M, Hall R, Fowler R for the Canadian Critical Care Trials Group H1N1 Collaborative. Critically Ill Patients with Novel Swine Origin Influenza Virus A/H1N1 Infection in Canada JAMA 2009; 302(17):1872-1879.
  12. Henderson W, Dhingra V, Chittock D, Foster D, Hebert P, Cook DJ, Heyland D, Dodek P, Schulzer M, Ronco R in association with the Canadian Critical Care Trials Group. The efficacy and Safety of Glucose Control Algorithms in Intensive Care: A Pilot Study of the Survival using Glucose Algorithm Regulation Trial (SUGAR). Polish Archives of Internal Medicine 2009;119:440-445.
  13. Doherty DR, Parshuram CS, Aparna Hoskote A, Lacroix J, Tucci M, Joffe A, Choong K, Gaboury I, Farrell R, Bohn DJ, Hutchison J, on behalf of the Canadian Critical Care Trials Group.   Hypothermia Therapy after Pediatric Cardio-respiratory Arrest.  Circulation 2009;119:1492-1500.
  14. Scales DC, Riva-Cambrin J, Le T, Pinto R, Cook DJ, Granton JT for the Canadian Critical Care Trials Group. Prophylaxis Against Venous Thromboembolism in Neuro-Intensive Care Patients: Survey of Canadian Practice.  J Crit Care 2009; 24(2):176-184.
  15. Scales DC, Orla M. Smith OM, Pinto R, Barrett KA, Friedrich JO, Lazar NM, Cook DJ, Ferguson ND for the Canadian Critical Care Trials Group.  Patients' Preferences For Enrolment into Critical Care Trials.  Intensive Care Medicine 2009; online June 24, 2009.
  16. The NICE SUGAR Study Investigators for the Australian and New Zealand Intensive Care Society, the George Institute for International Health, the Canadian Critical Care Trials Group, and the Vancouver Coastal Health Research Institute . Intensive versus conventional glucose control in critically ill patients.  N Engl J Med 2009;360(13):1283-1297.
  17. McIntyre LA, Fergusson D, Cook DJ, Rankin N, Dhingra V, Granton J, Magder S, Taljjard M, Hebert PC for the Canadian Critical Care Trials Group. Fluid Resuscitation in the Management of Early Septic Shock (FINESS): A pilot randomized controlled feasibility study Can J Anesth 2008, 55: 12; 819-826.
  18. Marshall JC, Cook DJ for the Canadian Critical Care Trials Group.  Investigator-led clinical research consortia: The Canadian Critical Care Trials Group.  Crit Care Med 2009; 36(7):S165-S172.
  19. Douketis J, Cook D, Meade M, Guyatt G, Geerts W, Skrobik Y, Albert M, Granton J, Hebert PC, Pagliarello G, Marshall JC, Fowler R, Freitag A, Rabbat C, Anderson D, Zytaruk N, Heels-Ansdell D, Crowther MA for the Canadian Critical Care Trials Group. Renal Insufficiency with the Low-molecular-weight Heparin Dalteparin: An Assessment of Safety and Pharmacodynamics. The DIRECT (Dalteparin's Influence on REnally Compromised anti-Ten-A) Study.  Arch Intern Med 2008;168(16):1805-1812.
  20. Mehta S, Burry L, Martinez-Motta C, Stewart TE, Hallett D, McDonald E, Clarke F, MacDonald R, Granton J, Matte A, Wong C, Suri A, Cook D for the Canadian Critical Care Trials Group.  A randomized trial of daily awakening in critically ill patients managed with a sedation protocol - A pilot study.  Crit Care Med 2008;36(7):2092-2099.
  21. Cook DJ, Blythe D, Rischbieth A, Hebert PC, Zytaruk N, Menon K, Erikson S, Fowler R, Heels-Ansdell D, Meade MO for the Canadian Critical Care Trials Group. Enrolment of ICU Patients into Clinical Studies: A Tri-national Survey.  Crit Care Med2008; 36(7):2100-2105.
  22. Hutchison SJ, Ward RE, Lacroix J, Hébert PC, Barnes MA, Bohn DJ, Dirks PB, Doucette S, Ferguson D, Gottesman R, Joffe AR, Kirpalani HM, Meyer PG, Morris KP, Moher D, Singh RN, Skippen PW, for the Hypothermia Pediatric Head Injury Trial investigators and the Canadian Critical Care Trials Group. Hypothermia Therapy Following Traumatic Brain Injury in Children. N Engl J Med 2008;358(24):47-56.
  23. Cheung CZ, Alibhai SMH, Robinson M, Tomlinson G, Chittock D, Drover J, Skrobik Y for the Canadian Critical Care Trials Group.  Recognition and labeling of delirium symptoms by intensivists: Does it matter?  Intensive Care Medicine 2008;34:437-446.
  24. Heyland DK, Dodek P, Muscedere J, Day A, Cook DJ for the Canadian Critical Care Trials Group.  A Randomized Trial of Combination Versus Monotherapy for the Empiric Treatment of Suspected Ventilator-Associated Pneumonia.  Crit Care Med 2008; 36: 737-744.
  25. Muscedere J, Dodek PE, Keenan S, Fowler R, Cook DJ, Heyland DK for the VAP Guidelines Committee and the Canadian Critical Care Trials Group.   Comprehensive Evidence-Based Clinical Practice Guidelines for Ventilator-Associated Pneumonia: Diagnosis and Treatment. J Crit Care 2008; 23: 138-147.
  26. Muscedere J, Dodek PE, Keenan S, Fowler R, Cook DJ, Heyland D for the VAP Guidelines Committee and the Canadian Critical Care Trials Group.  Comprehensive Evidence-Based Clinical Practice Guidelines for Ventilator-Associated Pneumonia: Prevention.  J Crit Care 2008; 23: 126-137.
  27. Sinuff T, Muscedere J, Cook D, Dodek P, Heyland D for the Canadian Critical Care Trials Group.  Ventilator-associated pneumonia: Improving outcomes through guideline implementation.  J Crit Care 2008; 23: 118-125.
  28. Joffe AR, Muscedere J, Marshall JC, Su Y, Heyland DK for the Canadian Critical Care Trials Group. The safety of targeted antibiotic therapy for ventilator-associated pneumonia: A multicenter observational study.  J Crit Care 2008; 23: 82-90 
  29. Albert M, Friedrich JO, Adhikari NKJ, Day AG, Verdant C, Heyland DK for the   Canadian Critical Care Trials Group. Utility of gram stain in the clinical management of suspected ventilator-associated pneumonia: Secondary analysis of a multicenter randomized trial. J Crit Care 2008; 23: 74-81.
  30. Shorr AF, Cook D, Jiang X, Muscedere J, Heyland D for the Canadian Critical Care Trials Group.  Correlates of clinical failure in ventilator-associated pneumonia: Insights from a large, randomized trial.  J Crit Care 2008; 23: 64-73.
  31. Sanders KM, Adhikari N, Friedrich JO, Day A, Jiang S, Heyland D for the Canadian Critical Care Trials Group.  Previous cultures are not clinically useful for guiding empiric antibiotics in suspected ventilator-associated pneumonia: Secondary analysis from a randomized trial.  J Crit Care 2008; 23: 58-63.
  32. Lauzier F, Ruest A, Cook D, Dodek P, Albert M, Shorr AF, Day A, Jiang X, Heyland D for the Canadian Critical Care Trials Group. The value of pretest probability and modified clinical pulmonary infection score to diagnose ventilator-associated pneumonia.  J Crit Care 2008; 23: 50-57.
  33. Muscedere JG, McColl C, Shorr A, Jiang X, Marshall J, Heyland DK for the Canadian Critical Care Trials Group.  Determinants of outcome in patients with a clinical suspicion of ventilator-associated pneumonia.  J Crit Care 2008; 23: 41-49.
  34. Parker CM,  Kutsogiannis J, Muscedere J, Cook D, Dodek P, Day AG, Heyland DK for the Canadian Critical Care Trials Group.  Ventilator-associated pneumonia caused by multidrug-resistant organisms or Pseudomonas aeruginosa: Prevalence, incidence, risk factors, and outcomes.  J Crit Care 2008;23: 18-26. 
  35. Delisle MS, Williamson DR, Perreault MM, Albert M, Jiang X, Heyland DK.  The clinical significance of Candida colonization of respiratory tract secretions in critically ill patients.  J Crit Care 2008; 23: 11-17.
  36. Muscedere JG, Martin CM, Heyland DK.  The impact of ventilator-associated pneumonia on the Canadian health care system.  J Crit Care 2008; 23: 5-10.
  37. McIntyre LL, Fergusson D, Cook DJ, Nair RC, Bell D, Dhingra V, Hutton B, Magder S, Hébert PC for the Canadian Critical Care Trials Group. Resuscitating patients with early severe sepsis: A Canadian multicenter observational study.  Can J Anesth 2007;54:779-785.
  38. McIntyre LA, Hebert PC, Fergusson D, Cook DJ, Aziz A for the Canadian Critical Care Trials Group. A Survey of Canadian Intensivists Resuscitation Practices in Early Septic Shock. Crit Care 2007;11:R74-79.
  39. Lacroix J, Hébert PC, Hutchison JS, Hume HA, Tucci M, Ducruet T, Gauvin F, Collet JP, Toledano BJ, Robillard P, Joffe A, Biarent D, Meert K, Peters MJ on behalf of the TRIPICU investigators, for the Canadian Critical Care Trials Group and the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. Transfusion Requirements In Pediatric Intensive Care Units: A Noninferiority Trial. N Engl J Med 2007;356(16):1609-1619.
  40. The Canadian Critical Care Trials Group. A randomized trial of diagnostic techniques and empiric  broad-spectrum antibiotics for suspected ventilator-associated pneumonia.  N Engl J Med 2006;355(25):2619-2630.
  41. Cook DJ, Rocker G, Marshall J, Griffith L, McDonald E, Guyatt GH for the Level of Care Study Investigators and the Canadian Critical Care Trials Group. Levels of Care in the Intensive Care Unit: A Research Program. Am J of Crit Care 2006; 15:269-279.
  42. McIntyre L, Fergusson D, Hutchinson J, Pagliarello G, Marshall J, Yetisir E, Hare GMT, Blajchman MJ, Hebert PC for The Canadian Care Trials Group.  Effect of a liberal versus restrictive transfusion strategies on mortality in patients with moderate to severe head injury? J Neuro Critical Care 2006;5:4-9.
  43. Hutchison J, Ward R, Lacroix J, Hébert P, Skippen P, Barnes M,  Meyer P, Morris K, Kirpalani H, Singh R, Dirks P, Bohn D, Moher D, for the HyP-HIT investigators and the Canadian Critical Care Trials Group. Hypothermia Pediatric Head Injury Trial (HyP-HIT): The value of a pre-trial clinical evaluation phase.  Developmental Neuroscience 2006;28:291-301.
  44. Cheung AM, Tansey CM, Tomlinson G, Diaz-Granados N, Matte-Martyn A, Mehta S, Mazer D, Guest CB, Stewart TE, Al-Saidi F, Cooper AB, Cook DJ, Slutsky AS, Herridge MS for The Canadian Critical Care Trials Group. Two-year health care utilization, costs and outcomes in survivors of the acute respiratory distress syndrome.  Am J Resp Crit Care Med 2006; 174:538-544.  
  45. Heyland DK, Dhaliwal R, Day A, Muscedere J, Drover J, Suchner U, Cook DJ, For the Canadian Critical Care Trials Group.  REducing Deaths due to OXidative Stress: The REDOXS© Study: Rationale and study design for a randomized trial of glutamine and antioxidant supplementation in critically ill patients.   Proc Nutr Soc 2006;65(3):250-263.
  46. Parshuram CS, Mehta G, Kirpalani H, Granton J, Cook DJ, for The Canadian Critical Care Trials Group.  In-house, overnight physician staffing:  A cross-sectional survey of Canadian adult and paediatric ICUs.  Crit Care Med 2006;34(6):1674-1678.
  47. Mehta S, Burry L, Fischer S, Martinez-Motta JC, Hallett D, Bowman D, Wong C, Meade MO, Stewart TE, Cook DJ for The Canadian Critical Care Trials Group.  A Canadian survey of the use of sedatives, analgesics, and neuromuscular blocking agents in critically ill patients.  Crit Care Med 2006; 34:374-380.
  48. Hebert PC, Chin-Yee I, Fergusson D, Blajchman M, Martineau R, Clinch J, Olberg B for the Canadian Critical Care Trials Group.  A pilot trial evaluating the clinical effects of prolonged storage of red cell. Anasthesia and Analgesia 2005; 100(5):1433-38.
  49. Patel R, Cook DJ, Meade MO, Griffith L, Mehta S, Rocker G, Marshall J, Hodder R, Martin C, Heyland D, Peters S, Muscadere J, Soth M, Campbell N, Guyatt GH, for The Canadian Critical Care Trials Group.  Burden of illness:  Thrombo-embolism in critical care (BITEC) study.  J Crit Care 2005;20:341-347.
  50. Cook DJ, Rocker G, Meade MO, Guyatt GH, Geerts W, Anderson D, Skrobik Y, Hébert P, Albert M, Cooper DJ, Bates S, Caco C, Finfer S, Freitag A, Granton J, Jones G, Langevin S, Mehta G, Pagliarello G, Poirier G, Rabbat C, Schiff D, Griffith LE, Crowther MA, for the PROTECT Investigators and the Canadian Critical Care Trials Group. Prophylaxis of ThromboEmbolism in Critical Care Trial: (PROTECT): A Pilot Study.  J Crit Care 2005;20:364-372.
  51. Kotsakis A, Cook DJ, Griffith LE, Anton N, Massicotte P, MacFarland K, Farrell R, Hutchison J, for the Canadian Critical Care Trials Group.  Clinically Important Venous Thromboembolism in Pediatric Critical Care: A Canadian Survey.  J Crit Care 2005;20:373-380.
  52. Liet JM, Millotte B, Tucci M, LaFlamme S, Hutchison J, Creery D, Ducruet T, Lacroix J, for The Canadian Critical Care Trials Group.  Non-invasive therapy with helium-oxygen for severe RSV bronchiolitis:  A multicenter randomized controlled trial. J Pediatrics 2005;147:812-817.
  53. Cook DJ, Meade MO, Guyatt GH, Griffith LE, Granton J, Geerts W, Crowther M for the Canadian Critical Care Trials Group. Clinically important deep vein thrombosis in the ICU: A survey of intensivists. Crit Care 2004;8:R145-R152.
  54. Sinuff T, Cook DJ, Rocker GM, Griffith L, Walter SD, Fisher M, Dodek P, Sjokvist P, McDonald E, Marshall J, Levy M, Guyatt G, and The Canadian Critical Care Trials Group.  Resuscitation directives in the intensive care unit.  Can J Anesth 2004;51(10):1034-1041.
  55. Hébert PC, Fergusson DA, McIntyre LL, Martin C, Doucette S,  Blajchman M, Graham ID,for the The Canadian Critical Care Trials Group. Revisiting transfusion practices in critically ill patients. Crit Care Med 2005;33:7-12.

  56. McIntyre L, Hébert PC, Wells G, Fergusson D, Marshall J, Yetisir E, Blajchman MJ, for The Canadian Critical Care Trials Group.  Is a restrictive transfusion strategy safe in resuscitated and critically ill trauma victims? Journal of Trauma Injury Infection and Critical Care 2004;57(3):563-568.
  57. Griffith L, Cook D, Hanna S, Rocker G, Sjokvist P, Dodek P, Marshall JC, Levy M, Varon J, Finfer S, Jaeschke R, Buckingham L, Guyatt G for The Canadian Critical Care Trials Group.  Predictors of clinician discomfort with daily life support plans for mechanically ventilated patients.  Intensive Care Med 2004;30:1783-1790.
  58. Rocker G, Cook D, Sjokvist P, Weaver B, Finfer S, McDonald E, Marshall J, Kirby A, Levy M, Dodek P, Heyland D, Guyatt G, for the Canadian Critical Care Trials Group.  Clinician predictions of mortality in the intensive care unit. Crit Care Med 2004;32(5):1149-1154.
  59. Dodek PM, Cook DJ, Keenan S, Heyland DK, Brun-Buisson C, Hall R, Jacka M, Foster D, Hand L, Mehta N, Muscedere J, for The Canadian Critical Care Trials Group.  Evidence based clinical practice guideline for the prevention of ventilator-associated pneumonia.  Ann Intern Med 2004;141:305-313.
  60. Meade MO, Jacka MJ, Cook DJ, Dodek P, Griffith L, Guyatt GH, for The Canadian Critical Care Trials Group.  A provincial survey of interventions for the prevention and treatment of acute respiratory distress syndrome. Crit Care Med 2004;32(4):946-954.
  61. Guyatt G, Cook D, Weaver B, Rocker G, Dodek P, Sjokvist P, Hamielec C, Puksa S, Marshall J, Foster D, Levy M, Varon J, Thorpe K, Fisher M, Walter S for the Level of Care Investigators and The Canadian Critical Care Trials Group.  The influence of perceived functional and employment status on cardiopulmonary resuscitation directives.  J Crit Care 2003;18(3):133-141.
  62. Cook DJ, Rocker G, Marshall J, Sjokvist P, Dodek P, Griffith L, Freitag A, Varon J, Bradley C, Levy M, Finfer S, Walter, S Guyatt GH, for the Level of Care Study Investigators and  The Canadian Critical Care Trials Group.  Withdrawal of mechanical ventilation in anticipation of death in the intensive care unit.  N Engl J Med 2003;349:1123-1132.
  63. Herridge MS, Cheung AM, Tansey CM, Matte-Martyn A, Diaz-Granados N, Al-Saidi F, Cooper A, Guest C, Mazer D, Mehta S, Stewart T, Barr A, Cook DJ, Slutsky A, for The Canadian Critical Care Trials Group.  One year outcomes in survivors of the acute respiratory distress syndrome N Engl J Med 2003;348:683-93.
  64. Sandham JD, Hull RD, Brant RF, Knox L, Pineo GF, Doig CJ, Laporta DP, Viner S, Passerini L, Devitt H, Kirby A, Jacka M, for The Canadian Critical Care Trials Group.  A randomised controlled trial of the use of pulmonary-artery catheters in high-risk surgical patients  N Engl J Med 2003;38:5-14.
  65. Laverdiere C, Gauvin F, Hébert PC, Infante-Rivard C, Hume H, Toledano BJ, Guertin M-C, Lacroix J, for The Canadian Critical Care Trials Group.  Survey on transfusion practices of pediatric intensivists.  Pediatric Crit Care Med 2002;3:335-340.
  66. Cook DJ, Guyatt GH, Rocker G, Sjokvist P, Weaver B, Dodek P, Marshall J, Leasa D, Levy M, Varon J, Fisher M, Cook DJ, for The Canadian Critical Care Trials Group.  Cardiopulmonary resuscitation directives on admission to the Intensive Care Unit: an international observational study.  Lancet 2001;358:1941-1945.
  67. Cook R, Cook DJ, Tilley J, Lee KA, Marshall J, for The Canadian Critical Care Trials Group.  Multiple organ dysfunction: Baseline and serial component scores. Crit Care Med 2001;29(11):2046-2050.
  68. Hébert PC, Blajchman MA, Cook DJ, Yetisir E, Wells G, Marshall J, Schweitzer I, and the Transfusion Requirements in Critical Care Investigators for The Canadian Critical Care Trials Group.  Do blood transfusions improve outcomes from mechanical ventilation? Chest 2001;119(6):1850-1857.
  69. Cook DJ, Heyland D, Marshall J, for The Canadian Critical Care Trials Group.  On the need for observational studies to design and interpret randomized trials in ICU patients: a case study in stress ulcer prophylaxis.  Intensive Care Med  2001;27:347-354.
  70. Heyland DK, Wood G, Cook DJ, for The Canadian Critical Care Trials Group.  Is the stomach an important source of tracheal contamination and subsequent pneumonia?  Clin Intensive Care 2001;12(1):29-35.
  71. Hébert PC, Yetisir E, Martin C, Blajchman MA, Wells G, Marshall J, Tweeddale M, Pagliarello G, Schweitzer I, and the Transfusion Requirements in Critical Care Investigators for The Canadian Critical Care Trials Group.  Is a low transfusion threshold safe in critically ill patients with cardiovascular diseases?  Crit Care Med  2001;29(2):227-234.
  72. Foster D, Cook DJ, Granton J, Steinberg M, Marshall J. for The Canadian Critical Care Trials Group. Use of a screen log to audit patient recruitment into multiple randomized trials in the ICU.  Crit Care Med 2000;28(3):867-871.
  73. Cook DJ, Heyland D, Griffith LE, Cook RJ, Marshall JC, Pagliarello G, for The Canadian Critical Care Trials Group.  Risk factors for clinically important upper gastrointestinal bleeding in patients requiring mechanical ventilation.  Crit Care Med 1999;27(12):2812-2817.
  74. Cook DJ, Giacomini M, Johnson N, Willms D, for The Canadian Critical Care Trials Group.  Life support in the intensive care unit:  a qualitative investigation of technological purposes.  Can Med Assoc J 1999;161(9):1109-1113.
  75. Heyland DK, Cook DJ, Schoenfeld PS, Freitag A, Varon J, Wood G, for The Canadian Critical Care Trials Group.  The effect of acidified enteral feeds on gastric colonization in critically ill patients:  Results of a multicenter randomized trial.  Crit Care Med 1999;27(11):2399-1406.
  76. Hébert PC, Wells G, Martin C, Tweeddale M, Marshall J, Blajchman M, Pagliarello G, Sandham D, Schweitzer I, Boisvert D, Calder L, for the Transfusion Requirements in Critical Care (TRICC) Investigators and The Canadian Critical Care Trials Group. Variation in red cell transfusion practice in the intensive care unit.  Crit Care 1999;3(2):57-63.
  77. Heyland DK, Cook DJ, Marshall J, Heule M, Guslits B, Lang J, Jaeschke R, for The Canadian Critical Care Trials Group.  The clinical utility of invasive diagnostic techniques in the setting of ventilator-associated pneumonia.  Chest 1999;115(4):1076-1084.
  78. Heyland DK, Cook DJ, Griffith LE, Keenan SP, Brun-Buisson C, for The Canadian Critical Care Trials Group.  The attributable morbidity and mortality of ventilator-associated pneumonia.  Am J Respir Crit Care Med 1999;159(4):1249-1256.
  79. Hébert PC, Wells G, Blajchman MA, Marshall J, Martin C, Pagliarello G, Tweeddale M, Schweitzer I, Yetisier E and the Transfusion Requirements in Critical Care Investigators, for The Canadian Critical Care Trials Group.  Transfusion requirements in critical care:  a multicenter randomized controlled clinical trial.  N Engl J Med 1999;340(6):409-417.
  80. Hébert PC for the Transfusion Requirements in Critical Care Investigators and The Canadian Critical Care Trials Group.  Transfusion requirements in critical care:  a multicentre randomized controlled clinical study.  Br J Anaesth 1998;81(Suppl):25-34.
  81. Cook DJ, Walter SD, Freitag A, Guyatt GH, Devitt H, Meade MO, Griffith LE, Sarabia A, Fuller, H, Turner M, Gough K, for The Canadian Critical Care Trials Group.  Lessons from adjudicating pneumonia in a randomized trial of critically ill patients.  J Crit Care 1998;13(4):159-163.
  82. Cook DJ, Walter S, Cook RJ, Griffith LE, Guyatt GH, Leasa D, Jaeschke R, Brun-Buisson C, for The Canadian Critical Care Trials Group.  Incidence of and risk factors for ventilator-associated pneumonia in critically ill patients.  Ann Intern Med 1998;129(6):433-440.
  83. Cook DJ, Guyatt GH, Marshall J, Leasa D, Fuller H, Hall R, Peters S, Rutledge F, Griffith L, McLellan PA, Wood G, Kirby A, Tweeddale M, Pagliarello J, Johnston R, for The Canadian Critical Care Trials Group.  A comparison of sucralfate and ranitidine for prevention of upper gastrointestinal bleeding in patients requiring mechanical ventilation.  N Engl J Med 1998;338(12):791-797.
  84. Hébert PC, Wells G, Tweeddale M, Martin C, Marshall JC, Pham B, Blajchman M, Schweitzer I, Pagliarello G for the Canadian Critical Care Trials Group.  Does transfusion practice affect mortality in critically ill patients?  Am J Resp Crit Care Med 1998;155:1618-1623.
  85. Hébert PC, Wells G, Martin C, Tweeddale M, Marshall J, Blajchman M, Pagliarello G, Schweitzer I, Calder L, for the Transfusion Requirements in Critical Care Investigators and The Canadian Critical Care Trials Group.  A Canadian survey of transfusion practices in critically ill patients.  Crit Care Med 1998;26(3):482-487.
  86. Walter S, Cook DJ, Guyatt GH, Spanier A, Jaeschke R, Todd T, Streiner DL, for The Canadian Critical Care Trials Group.  Confidence and decision making in the withdrawal of life support from the critically ill.  Crit Care Med 1998;26(1):44-49.
  87. Cook DJ, Todd TRJ.  The Canadian Critical Care Trials Group:  A collaborative, educational organisation for the advancement of adult ICU research.  Intens Care World 1997;14(2):68-70.
  88. Heyland DK, Gafni A, Griffith L, Cook DJ, Marshall JC, Fuller HD, Todd TRJ, Guslits B, Heule M, Hewson JR, Lacroix J, Noseworthy T, Powles ACP, for The Canadian Critical Care Trials Group.  The clinical and economic consequence of clinically important gastrointestinal bleeding in critically ill patients.  Clin Intens Care 1996;7(3):121-125.
  89. Cook DJ, Guyatt GH, Jaeschke R, Reeve J, Spanier A, King D, Molloy DW, Willan A, Streiner D, for The Canadian Critical Care Trials Group. Determinants in Canadian health care workers of the decision to withdraw life support from the critically ill.  JAMA 1995;273(9):703-708.
  90. Hébert PC, Wells G, Marshall JC, Martin C, Tweeddale M, Pagliarello G, Blajchman M, for The Canadian Critical Care Trials Group.  Transfusion requirements in critical care:  A pilot study.  JAMA 1995;273:1439-1444.
  91. Cook DJ, Fuller H, Guyatt GH, Marshall JC, Leasa D, Hall R, Winton TL, Rutledge F, Todd TRJ, Roy P, Lacroix J, Griffith LE, Willan A, for The Canadian Critical Care Trials Group.  Risk factors for gastrointestinal bleeding in critically ill patients.  N Engl J Med 1994;330:377-381.

 

  
     
 
 

Home | About Us | News & Events | Publications | Grants | Links
 

© 2005, CCCTG. All rights reserved.