• Canadian Critical Care Trials Group
    The Canadian Critical Care Trials Group (CCCTG) is a highly collegial group that is dedicated to the pursuit of excellence and advancement of critical care research in Canada.
  • Canadian Critical Care Trials Group
    The CCCTG has are more than 30 research programs underway and over 100 peer-reviewed publications to its credit, with direct impact on clinical practice in critical care.
  • Canadian Critical Care Trials Group
    The Canadian Critical Care Trials Group (CCCTG) is a national organization of more than 300 individuals with research interests in the management of the critically ill patient.
  • Canadian Critical Care Trials Group
    Endorsement by the CCCTG communicates our full commitment to ensure that the work is undertaken in a rigorous and ethical manner, and communicated in a timely and effective way.

Recipients of the 2015 CCCTG Research Fellowship Awards

CONGRATULATIONS to Drs. Kimberly Macala and Simon Oczkowski!

The CCCTG has a long and successful history of developing and facilitating investigator-initiated, patient-focused, multi-centre research programs. We strive to improve the lives and quality of care of critically ill adults and children by conducting relevant research and evaluation of care in response to health care needs.  We are also devoted to build strong, sustainable career development and mentorship programs for researchers and research coordinators at all career stages, across disciplines, and including the Intensive Care Units of community’s hospitals. The Fellowship Award program provides support for highly qualified candidates in the areas of critical care that are relevant to the CCCTG at the post-PhD degree or the post-health professional degree stages to add to their experience by engaging in health research in Canada.

The specific objectives of the CCCTG Research Fellowship Awards are to:
  • Promote critical care research in Canada;
  • Provide a reliable supply of highly skilled and qualified critical care researchers;
  • Provide recognition and funding to academic critical care researchers at the beginning of their career;
  • Enhance the culture of science and innovation within the critical care community;
  • Improve the health and health care delivered to critically ill patients through knowledge creation and knowledge translation.

The research projects funded in 2015 are:



Dr. Kimberly Macala, Department of Critical Care Medicine, University of Alberta

In her project entitled Preclinical testing of novel treatment strategies for septic shock in a mouse model of advanced age, Dr. Macala aims to examine the blood pressure and cardiac changes in an aged versus adult septic models to better define the aged response to sepsis.  This study will examine bloodwork, tissue and organ samples for evidence of differing effects of sepsis on the aged organ systems that may possibly contribute to increased death.  Three novel medications will be tested separately and in combination, that have been shown to have hemodynamic benefits in healthy models, but not used previously in sepsis.  This study will equip physicians with a better understanding of the older patient's response to sepsis with the goal of developing strategies to improve the care of older critically ill patients.

We are thankful to the Critical Care Strategic Clinical Network and Alberta Health Services for their support to the CCCTG Research Fellowship Award by providing matched funds to Dr. Macala.


Dr. Simon Oczkowski, Division of Critical Care of the Department of Medicine, McMaster University

In his project entitled The Canada-DONATE Clinical Qualitative Study: A mixed-method study of the organ donation process in a high-volume intensive care unit, Dr. Oczkowski aims to discover potential facilitators and barriers which affect the identification and management of organ donors. The study will incorporate both quantitative and qualitative data in order to provide descriptive statistics and rich descriptions, culminating in development of a theoretical model of the organ donation process. The study will have three phases consisting of 1) a document analysis describing policies and protocols relating to organ donation in the ICU; 2) a quantitative practice survey of HCPs who work in the ICU; and 3) a series of semi-structured interviews with HCPs who have recently managed potential donors in the ICU.  The study will provide a comprehensive model of how HCPs identify and manage potential organ donors, and a foundation for future interventions aimed at improving the rate of successful organ donation in the ICU.

We are thankful to the Division of Critical Care of the Department of Medicine, McMaster University, for their support to the CCCTG Research Fellowship Award by providing matched funds to Dr. Oczkowski.