• Excellence

    The Canadian Critical Care Trials Group (CCCTG) is a highly collegial group that is dedicated to the pursuit of excellence and advancement of critical care research in Canada.

  • National

    The CCCTG is a national organization of more than 350 individuals with research interests in the management of the critically ill patient.

  • Research

    The CCCTG has are more than 75 research programs underway and over 230 peer-reviewed publications to its credit, with direct impact on clinical practice in critical care.

  • Impact

    Endorsement by the CCCTG communicates our full commitment to ensure that the work is undertaken in a rigorous & ethical manner, and communicated in a timely & effective way to maximise impact.

  • Direction

    Leading Science, Saving Lives — 5-year Strategic Plan to further enhance the impact of the CCCTG in Canada and around the world.

  • Focus on
    Sedation management in the critically ill

    All critically ill, mechanically ventilated patients in the Intensive Care Unit receive medications to relieve pain and anxiety. However, accumulation of these medications can be associated with serious complications. Researchers from the CCCTG compared sedation strategies in critically ill mechanically ventilated patients.

  • Focus on
    How to define death?

    Article in Critical Care Medicine showed that it is feasible and acceptable to study the natural history of death after withdrawal of life sustaining therapy in the ICU.  The DePPaRT study aims to aims to provide much needed information to provide guidance to "donation after circulatory death (DCD)" practice.

  • Focus on
    Outcome and Research Priorities in Intensive Care Studies (OPTICS)

    The OPTICS research program lead by Drs. John Muscedere and François Lamontagne aims to understand differences in priorities between patients, citizens, decision-makers and researchers about research priorities and outcomes assessment in critical care clinical research.  Click on Learn More for a short video (in French only) presenting the OPTICS study.

  • Focus on
    Old blood as good as fresh blood in critically ill patients

    Blood used for transfusions is perishable. But contrary to general belief, results from a new study from CCCTG researchers published today in the New England Journal of Medicine shows that blood stored for three weeks is just as good as fresh blood.

  • Focus on
    Better treatment strategies for critically ill patients and the potential impact for the healthcare system

    The results of the PROTECT Trial and the recent corresponding cost-effectiveness study showed better health outcomes and overall, lower health care costs when using low molecular weight heparin dalteparin for the prevention of venous thromboembolism in the ICU.

  • Focus on
    Ebola Outbreaks - CCCTG Members at the Front

    Critical care clinicians François Lamontagne and Rob Fowler have made several trips to West Africa as part of the World Health Organization and Médecins sans Frontières.  Read their perspective in the New England Journal of Medicine on what constitute the primary barrier to efficient intervention and care.

  • Focus on
    Changes in Practice Reduces Need for Blood Transfusions.

    Article in The New York Times reveals transfusions are down almost one-third.  One reason cited for declining demand is that recent studies have found many transfusions unnecessary, so patients are no longer getting expensive services that did them no good.

  • Focus on
    Minister of Health and CIHR Messages for CCCTG's 25th Anniversary

    The CCCTG receives messages from Hon. Rona Ambrose, Minister of Health, and Dr. Alain Beaudet, President of the Canadian Institutes of Health Research congratulating the CCCTG on its 25th anniversary.

  • 2014 Annual Report

    We are pleased to announce the CCCTG 2014 Annual Activity Report is now available. Click Learn More to access it.

  • Fellowship

    Request for applications for the CCCTG Research Fellowship Award 2015.  The application deadline is Friday July 31, 2015 at 5 pm EDT.

  • 2015 Meeting

    The CCCTG Fall 2015 Scientific Meeting will be held October 24-25, 2015 at the Peter Gilgan Centre for Research and Learning (Hospital for Sick Children), Toronto ON.

  • CCCRCG

    The CCCRCG Fall 2015 Meeting will be held at the LiKaShing Knowledge Institute (St. Michael’s Hospital), Toronto ON October 23, 2015.

  • Dr. Menon

    Kusum Menon receives a Tier 2 Research Chair in Pediatric Shock from the University of Ottawa!

  • Dr. Lamontagne

    François Lamontagne receives a Research Chair on Critical Care Patients from the Université de Sherbrooke!

  • CCCF 2015

    The Critical Care Canada Forum 2015 will be held in Toronto ON, October 25-28, 2015.

  • Dr. Cook

    Deborah Cook has been named an Officer of the Order of Canada, one of our country’s highest civilian honours.

  • Dr. Meade

    In recognition to her exceptional contributions to the promotion of critical care research through mentorship, Maureen Meade receives the first Deborah J. Cook Mentorship Award.